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1. Full Text Efficacy, safety, and immunology of an inactivated alum-adjuvant enterovirus 71 vaccine in children in China: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
by Zhu, Feng-Cai, MSc and Meng, Fan-Yue, MSc and Li, Jing-Xin, MSc and Li, Xiu-Ling, MSc and Mao, Qun-Ying, PhD and Tao, Hong, BS and Zhang, Yun-Tao, PhD and Yao, Xin, PhD and Chu, Kai, MSc and Chen, Qing-Hua, MSc and Hu, Yue-Mei, BS and Wu, Xing, MSc and Liu, Pei, PhD and Zhu, Lin-Yang, BS and Gao, Fan, MSc and Jin, Hui, PhD and Chen, Yi-Juan, MSc and Dong, Yu-Ying, MSc and Liang, Yong-Chun, BS and Shi, Nian-Min, MSc and Ge, Heng-Ming, BS and Liu, Lin, BS and Chen, Sheng-Gen, BS and Ai, Xing, MSc and Zhang, Zhen-Yu, BS and Ji, Yu-Guo, BS and Luo, Feng-Ji, MSc and Chen, Xiao-Qin, BS and Zhang, Ya, BS and Zhu, Li-Wen, BS and Liang, Zheng-Lun, PhD and Shen, Xin-Liang, MSc
Lancet, The, ISSN 0140-6736, 2013, Volume 381, Issue 9882, pp. 2024 - 2032
Summary Background A vaccine for enterovirus 71 (EV71) is needed to address the high burden of disease associated with infection. We assessed the efficacy,... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | IMMUNOGENICITY | RISK-FACTORS | MOUTH-DISEASE | TAIWAN | INFECTION | CLINICAL-FEATURES | EPIDEMIC | PULMONARY-EDEMA | HAND | FOOT | Enterovirus Infections - prevention & control | Double-Blind Method | Humans | Enterovirus A, Human - immunology | Kaplan-Meier Estimate | Child, Preschool | Infant | Male | Viral Vaccines - adverse effects | Antibodies, Viral - blood | Adjuvants, Immunologic - adverse effects | Alum Compounds | Immunity, Active - physiology | Vaccines, Inactivated - adverse effects | Vaccines, Inactivated - immunology | Enterovirus Infections - immunology | Female | Viral Vaccines - immunology | Prevention | Usage | Viral vaccines | Health aspects | Enterovirus diseases | Hospitals | Illnesses | Vaccines | Family medical history | Drug dosages | Antibodies
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2. Full Text Sleep duration and risk of all-cause mortality: A flexible, non-linear, meta-regression of 40 prospective cohort studies
by Liu, Tong-Zu, PhD and Xu, Chang, MD and Rota, Matteo, PhD and Cai, Hui, PhD and Zhang, Chao, MD and Shi, Ming-Jun, PhD and Yuan, Rui-Xia, PhD and Weng, Hong and Meng, Xiang-Yu, MD and Kwong, Joey S.W., PhD and Sun, Xin, PhD
Sleep Medicine Reviews, ISSN 1087-0792, 2016, Volume 32, pp. 28 - 36
Summary Approximately 27–37% of the people experienced prolonged sleep duration and 12–16% reported shortened sleep duration. However, prolonged or shortened... 
Neurology | Sleep Medicine | All-cause mortality | Sleep duration | Dose–response relationship | Meta-analysis | C-REACTIVE PROTEIN | BLADDER-CANCER | OLDER-ADULTS | 9-YEAR FOLLOW-UP | NEUROSCIENCES | CLINICAL NEUROLOGY | DOSE-RESPONSE DATA | HEALTHY-ADULTS | Dose-response relationship | CARDIOVASCULAR-DISEASE | PHYSICAL-ACTIVITY | NIGHTTIME SLEEP | GENDER-DIFFERENCES | Mortality - trends | Sleep Wake Disorders - mortality | Time Factors | Humans | Risk Factors | Sex Factors | Medical colleges | Yuan (China) | Sleep | Health aspects | Mortality | Epidemiology
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3. Full Text Transmission of multidrug-resistant Mycobacterium tuberculosis in Shanghai, China: a retrospective observational study using whole-genome sequencing and epidemiological investigation
by Yang, Chongguang, PhD and Luo, Tao, PhD and Shen, Xin, PhD and Wu, Jie, MPH and Gan, Mingyu, MSc and Xu, Peng, PhD and Wu, Zheyuan, MSc and Lin, Senlin, MSc and Tian, Jiyun, MSc and Liu, Qingyun, PhD and Yuan, ZhengAn, MSc and Mei, Jian, PhD and DeRiemer, Kathryn, PhD and Gao, Qian, Dr
Lancet Infectious Diseases, The, ISSN 1473-3099, 2017, Volume 17, Issue 3, pp. 275 - 284
Summary Background Multidrug-resistance is a substantial threat to global elimination of tuberculosis. Understanding transmission patterns is crucial for... 
Infectious Disease | ANTIBIOTIC-RESISTANCE | POPULATION | INFECTIOUS DISEASES | MUTATIONS | EPIDEMICS | BURDEN | Genome, Bacterial | Humans | Middle Aged | Antitubercular Agents - pharmacology | Male | Tuberculosis, Multidrug-Resistant - genetics | Sequence Analysis, DNA | Tuberculosis, Multidrug-Resistant - epidemiology | Mycobacterium tuberculosis - isolation & purification | Molecular Epidemiology | China | Adolescent | Tuberculosis, Multidrug-Resistant - transmission | Adult | Female | Aged | Polymorphism, Single Nucleotide | Retrospective Studies | Drug Resistance, Multiple, Bacterial - genetics | Mycobacterium tuberculosis - genetics | Prevention | Drug resistance in microorganisms | Tuberculosis | Disease transmission | Genomics | Genetic research | Nucleotide sequencing | Epidemiology | Investigations | Risk factors | DNA sequencing | Medical research | Genomes | Analysis | Medicine, Experimental | Single nucleotide polymorphisms | Chromosomes | Rifampin | Studies | Epidemics | Population | multidrug-resistance | recent transmission | whole-genome sequencing
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4. Full Text Immunogenicity and safety of an enterovirus 71 vaccine in healthy Chinese children and infants: a randomised, double-blind, placebo-controlled phase 2 clinical trial
by Zhu, Feng-Cai, MSc and Liang, Zheng-Lun, PhD and Li, Xiu-Ling, MSc and Ge, Heng-Ming, BSc and Meng, Fan-Yue, MSc and Mao, Qun-Ying, PhD and Zhang, Yun-Tao, PhD and Hu, Yue-Mei, BSc and Zhang, Zhen-Yu, BSc and Li, Jing-Xin, MSc and Gao, Fan, MSc and Chen, Qing-Hua, MSc and Zhu, Qi-Yan, BSc and Chu, Kai, MSc and Wu, Xing, MSc and Yao, Xin, PhD and Guo, Hui-Jie, MSc and Chen, Xiao-Qin, BSc and Liu, Pei, Prof and Dong, Yu-Ying, MSc and Li, Feng-Xiang, PhD and Shen, Xin-Liang, MSc and Wang, Jun-Zhi, Dr
Lancet, The, ISSN 0140-6736, 2013, Volume 381, Issue 9871, pp. 1037 - 1045
Summary Background Enterovirus 71 (EV71) outbreaks are a socioeconomic burden, especially in the western Pacific region. Results of phase 1 clinical trials... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | MOUTH-DISEASE | TOLERABILITY | ANTIBODY | INFECTION | HAND | FOOT | SCHEDULES | Enterovirus Infections - prevention & control | Double-Blind Method | Humans | Enterovirus A, Human - immunology | Child, Preschool | Infant | Male | Treatment Outcome | Viral Vaccines - adverse effects | Antibodies, Viral - blood | Immunity, Cellular - drug effects | Antibody Formation - drug effects | Female | Viral Vaccines - immunology | Enteroviruses | Immunology | Safety and security measures | Demographic aspects | Physiological aspects | Chinese | Infants | Research | Vaccines | Health aspects | Health care | Mortality | Infections | Autoimmune diseases | Drug dosages | Children & youth | Adjuvants
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5. Full Text CXCL12/CXCR4 axis promotes mesenchymal stem cell mobilization to burn wounds and contributes to wound repair
by Hu, Changjiang, PhD and Yong, Xin, PhD and Li, Changzhu, PhD and Lü, Muhan, PhD and Liu, Dengqun, PhD and Chen, Lin, PhD and Hu, Jiongyu, PhD and Teng, Miao, PhD and Zhang, Dongxia, PhD and Fan, Yahan, PhD and Liang, Guangping, PhD
Journal of Surgical Research, ISSN 0022-4804, 2013, Volume 183, Issue 1, pp. 427 - 434
Abstract Background Bone marrow–derived mesenchymal stem cells (BM-MSCs) play a crucial role in tissue repair. Their role in thermal burn wound regeneration... 
Surgery | CXCR4 | CXCL12 | Bone marrow–derived mesenchymal stem cells | Burn wound | Bone marrow-derived mesenchymal stem cells | MIGRATION | SURGERY | CHEMOKINES | BONE-MARROW | INJURY | SDF-1 | MODEL | IN-VITRO | LIVER | Re-Epithelialization | Green Fluorescent Proteins | Mice, Inbred C57BL | Male | Mice, Transgenic | Chemotaxis | Receptors, CXCR4 - metabolism | Hair Follicle - cytology | Animals | Chemokine CXCL12 - metabolism | Burns - metabolism | Female | Mice | Mesenchymal Stromal Cells - physiology | Chimera | Epidermis - cytology | Care and treatment | Burns and scalds | Wounds and injuries | Stem cells
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6. Full Text miR-187-3p inhibits the metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting S100A4
by Dou, Changwei, MD and Liu, Zhikui, MD and Xu, Meng, MD and Jia, Yuli, MD and Wang, Yufeng, MD and Li, Qing, MD and Yang, Wei, PhD, MD and Zheng, Xin, PhD, MD and Tu, Kangsheng, PhD, MD and Liu, Qingguang, PhD, MD
Cancer Letters, ISSN 0304-3835, 2016, Volume 381, Issue 2, pp. 380 - 390
Highlights of this study • MiR-187-3p is significantly down-regulated in HCC, and is correlated with adverse clinical features and poor prognosis of HCC... 
Hematology, Oncology and Palliative Medicine | Hepatocellular carcinoma | miR-187-3p | S100A4 | Metastasis | EMT | MIGRATION | TUMOR PROGRESSION | PROGNOSIS | MICRORNAS | HYPOXIA | BREAST-CANCER | INVASIVENESS | ONCOLOGY | THERAPEUTIC TARGET | GROWTH | REGULATORS | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Male | MicroRNAs - metabolism | Carcinoma, Hepatocellular - secondary | Tumor Hypoxia | Transfection | RNA Interference | S100 Calcium-Binding Protein A4 - genetics | Time Factors | Carcinoma, Hepatocellular - genetics | Epithelial-Mesenchymal Transition | Female | Liver Neoplasms - pathology | Liver Neoplasms - genetics | Signal Transduction | Neoplasm Invasiveness | Kaplan-Meier Estimate | Carcinoma, Hepatocellular - surgery | Liver Neoplasms - surgery | Disease Progression | Hep G2 Cells | Disease-Free Survival | Animals | Mice, Nude | Liver Neoplasms - metabolism | MicroRNAs - genetics | S100 Calcium-Binding Protein A4 - metabolism | Carcinoma, Hepatocellular - metabolism | Cell Movement | Stem cells | Genotype & phenotype | Liver cancer | Wound healing | Medical prognosis | MicroRNAs | Conflicts of interest | Hypoxia | Breast cancer | Lymphomas | Gene expression
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7. Full Text Immunity duration of a recombinant adenovirus type-5 vector-based Ebola vaccine and a homologous prime-boost immunisation in healthy adults in China: final report of a randomised, double-blind, placebo-controlled, phase 1 trial
by Li, Jing-Xin, PhD and Hou, Li-Hua, PhD and Meng, Fan-Yue, MSc and Wu, Shi-Po, PhD and Hu, Yue-Mei, BS and Liang, Qi, BS and Chu, Kai, MSc and Zhang, Zhe, BS and Xu, Jun-Jie, PhD and Tang, Rong, MSc and Wang, Wen-Juan, MSc and Liu, Pei, Prof and Hu, Jia-Lei, MSc and Luo, Li, MSc and Jiang, Rong, MSc and Zhu, Feng-Cai, MSc and Chen, Wei, PhD
Lancet Global Health, ISSN 2214-109X, 2017, Volume 5, Issue 3, pp. e324 - e334
Summary Background The 2013–15 Ebola virus disease epidemic in west Africa greatly accelerated the development of Ebola vaccine. We aimed to analyse the immune... 
Internal Medicine | NONHUMAN-PRIMATES | MVA | PROTECTIVE IMMUNITY | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | VIRUS INFECTION | DISEASE | Adenoviridae | Double-Blind Method | Hemorrhagic Fever, Ebola - prevention & control | Humans | Middle Aged | Vaccination | Male | Vaccines, Synthetic - immunology | Ebolavirus - immunology | Immunization, Secondary | China | Hemorrhagic Fever, Ebola - virology | Adult | Ebola Vaccines - immunology | Female | Genetic Vectors
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8. Full Text Prognostic factors in malignant sublingual salivary gland tumors
by Liu, Yanbin, DDS, PhD and Li, Hong, DDS and Qin, Lizheng, DDS, PhD and Huang, Xin, DDS, PhD and Su, Ming, MD and Han, Zhengxue, DDS, PhD
Journal of Oral and Maxillofacial Surgery, ISSN 0278-2391, 2016, Volume 75, Issue 7, pp. 1542 - 1548
Abstract Purpose This study identified the prognostic factors and outcomes for malignant sublingual salivary gland tumors, which are rare. Materials and... 
Surgery | HEAD | SUBMANDIBULAR-GLAND | MANAGEMENT | DENTISTRY, ORAL SURGERY & MEDICINE | ADENOID CYSTIC CARCINOMA | NECK | RADIATION | CELL-CARCINOMA | Sublingual Gland Neoplasms - mortality | Prognosis | Sublingual Gland Neoplasms - surgery | Humans | Middle Aged | Male | Survival Rate | Neoplasm Metastasis | Adult | Female | Aged | Neoplasm Recurrence, Local - epidemiology | Retrospective Studies | Sublingual Gland Neoplasms - pathology | Cohort Studies | Medical colleges | Medical societies | Tumors | Medical research | Analysis | Mortality | Medicine, Experimental | Metastasis
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9. Full Text Meta-Analysis of Effects of Voluntary Slow Breathing Exercises for Control of Heart Rate and Blood Pressure in Patients With Cardiovascular Diseases
by Zou, Yan, MN and Zhao, Xin, PhD and Hou, Yun-Ying, MN and Liu, Ting, MN and Wu, Qing, MN and Huang, Yu-Hui, PhD and Wang, Xiao-Hua, PhD
American Journal of Cardiology, The, ISSN 0002-9149, 2017, Volume 120, Issue 1, pp. 148 - 153
Rising heart rate (HR) and elevated blood pressure (BP) cause a greater frequency of cardiovascular events. Many patients cannot maintain target HR and BP... 
Cardiovascular | CONTROLLED-TRIAL | CARDIAC & CARDIOVASCULAR SYSTEMS | ESSENTIAL-HYPERTENSION | RISK-FACTOR | FAILURE | Heart Rate - physiology | Cardiovascular Diseases - physiopathology | Blood Pressure - physiology | Humans | Breathing Exercises - methods | Cardiovascular Diseases - therapy | Care and treatment | Heart beat | Analysis | Cardiac patients | Blood pressure | Breathing exercises | Cardiovascular diseases | Heart attacks | Compliance | Syngeneic grafts | Bias | Clinical trials | Cardiovascular disease | Blood | Training | Quality | Xenografts | Heart diseases | Heart failure | Hypertension | Statistical analysis | Pharmacology | Patients | Coronary artery disease | Diseases | Meta-analysis | Heart rate | Studies | Reviews | Coronary vessels | Diabetes | Breathing | Respiration
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10. Full Text Poor Vitamin D Status Is Prospectively Associated with Greater Muscle Mass Loss in Middle-Aged and Elderly Chinese Individuals
by Liu, Gang, MSc and Lu, Ling, PhD and Sun, Qi, PhD and Ye, Xingwang, PhD and Sun, Liang, PhD and Liu, Xin, PhD and Zong, Geng, PhD and Jin, Qianlu and Li, Huaixing, PhD and Lin, Xu, MD, PhD
Journal of the Academy of Nutrition and Dietetics, ISSN 2212-2672, 2014, Volume 114, Issue 10, pp. 1544 - 1551.e2
Abstract Background Poor vitamin D status can increase age-related muscle mass loss. However, existing prospective evidence is limited and controversial.... 
Internal Medicine | Gastroenterology and Hepatology | Inflammation | 25-hydroxyvitamin D | Dual-energy x-ray absorptiometry | Cohort study | Muscle mass | KOREA NATIONAL-HEALTH | METABOLIC SYNDROME | BONE-MINERAL DENSITY | D SUPPLEMENTATION | D DEFICIENCY | OLDER CHINESE | SKELETAL-MUSCLE | NUTRITION & DIETETICS | FAT-FREE MASS | 25-HYDROXYVITAMIN D CONCENTRATION | PARATHYROID-HORMONE | Severity of Illness Index | Prospective Studies | Calcifediol - blood | Humans | Middle Aged | Sarcopenia - blood | Male | Biomarkers - blood | Sex Characteristics | Vitamin D Deficiency - physiopathology | Sarcopenia - physiopathology | Health Surveys | Sarcopenia - etiology | China | Sarcopenia - pathology | Aging | Female | 25-Hydroxyvitamin D 2 - blood | Aged | Nutritional Status | Muscle, Skeletal - pathology | Longitudinal Studies | Cohort Studies | Physiological aspects | Muscles | Calcifediol | Alfacalcidol | Vitamin D | Growth
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11. Full Text MicroRNAs in oral lichen planus and potential miRNA–mRNA pathogenesis with essential cytokines: a review
by Ma, Hui, MD, DDS and Wu, Yuanqin, MD, DDS and Yang, Huamei, MD, DDS and Liu, Jiajia, MD, DDS and Dan, Hongxia, PhD, DDS and Zeng, Xin, PhD, DDS and Zhou, Yu, PhD, DDS and Jiang, Lu, PhD, DDS and Chen, Qianming, PhD, DDS
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, ISSN 2212-4403, 2016, Volume 122, Issue 2, pp. 164 - 173
Oral lichen planus (OLP) is a potentially premalignant condition with unknown pathogenesis. Immune and inflammatory factors are thought to play important roles... 
Surgery | RHEUMATOID-ARTHRITIS | PRO-INFLAMMATORY CYTOKINES | TUMOR-NECROSIS-FACTOR | AUTOIMMUNE INFLAMMATION | NITRIC-OXIDE SYNTHASE | DENTISTRY, ORAL SURGERY & MEDICINE | REGULATES TNF-ALPHA | DOWN-REGULATION | CD4(+) T-CELLS | NF-KAPPA-B | FEEDBACK LOOP | Lichen Planus, Oral - prevention & control | Lichen Planus, Oral - pathology | Humans | Precancerous Conditions - pathology | MicroRNAs - genetics | Precancerous Conditions - prevention & control | Cytokines - genetics | Lichen Planus, Oral - genetics | Precancerous Conditions - genetics | Interferon | Messenger RNA | MicroRNA | Interleukins | Biological response modifiers | Lichen planus
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