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Human Molecular Genetics, ISSN 0964-6906, 2016, Volume 25, Issue 20, pp. 4556 - 4565
Lipid traits (total, low-density and high-density lipoprotein cholesterol, and triglycerides) are risk factors for cardiovascular disease. DNA methylation is... 
DENSITY-LIPOPROTEIN CHOLESTEROL | THIOREDOXIN INTERACTING PROTEIN | GENE PROMOTER | RISK-FACTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | FAMILIAL COMBINED HYPERLIPIDEMIA | BODY-MASS INDEX | ASSOCIATION | CORONARY-ARTERY-DISEASE | LOWERING DRUGS | BLOOD | Carnitine O-Palmitoyltransferase - genetics | Cholesterol - blood | Epigenesis, Genetic | Humans | Amino Acid Transport System y+ - genetics | Male | Genetic Loci | ATP Binding Cassette Transporter, Subfamily G, Member 1 - metabolism | Cardiovascular Diseases - enzymology | Cardiovascular Diseases - genetics | Cholesterol - chemistry | ras GTPase-Activating Proteins - genetics | DNA Methylation | Amino Acid Transport System y+ - metabolism | ATP Binding Cassette Transporter, Subfamily G, Member 1 - genetics | Carnitine O-Palmitoyltransferase - metabolism | Female | Lipid Metabolism - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Genetic Predisposition to Disease | Phosphoric Monoester Hydrolases - genetics | ras GTPase-Activating Proteins - metabolism | Cardiovascular Diseases - metabolism | Genetic Association Studies | Ubiquitin-Protein Ligases - metabolism | Cholesterol - metabolism | Sequence Analysis, DNA | Triglycerides - metabolism | Carrier Proteins - genetics | Carrier Proteins - metabolism | Sterol Regulatory Element Binding Protein 1 - genetics | Triglycerides - blood | CpG Islands | Triglycerides - genetics | Phosphoric Monoester Hydrolases - metabolism | Ubiquitin-Protein Ligases - genetics | Index Medicus | Epigènesi | ADN
Journal Article
by Simino, Jeannette and Shi, Gang and Bis, Joshua C and Chasman, Daniel I and Ehret, Georg B and Gu, Xiangjun and Guo, Xiuqing and Hwang, Shih-Jen and Sijbrands, Eric and Smith, Albert V and Verwoert, Germaine C and Bragg-Gresham, Jennifer L and Cadby, Gemma and Chen, Peng and Cheng, Ching-Yu and Corre, Tanguy and de Boer, Rudolf A and Goel, Anuj and Johnson, Andrew D and Johnson, Toby and Khor, Chiea-Chuen and Alizadeh, Behrooz Z and Boezen, H. Marike and Bruinenberg, Marcel and Franke, Lude and van der Harst, Pim and Hillege, Hans L and van der Klauw, Melanie M and Navis, Gerjan and Ormel, Johan and Postma, Dirkje S and Rosmalen, Judith G.M and Slaets, Joris P and Snieder, Harold and Stolk, Ronald P and Stolk, Ronald P and Wolffenbuttel, Bruce H.R and Wijmenga, Cisca and Lluís-Ganella, Carla and Luan, Jian’an and Lyytikäinen, Leo-Pekka and Nolte, Ilja M and Sim, Xueling and Sõber, Siim and van der Most, Peter J and Verweij, Niek and Zhao, Jing Hua and Amin, Najaf and Boerwinkle, Eric and Bouchard, Claude and Dehghan, Abbas and Eiriksdottir, Gudny and Elosua, Roberto and Franco, Oscar H and Gieger, Christian and Harris, Tamara B and Hercberg, Serge and Hofman, Albert and James, Alan L and Kähönen, Mika and Khaw, Kay-Tee and Kutalik, Zoltan and Larson, Martin G and Launer, Lenore J and Li, Guo and Liu, Kiang and Liu, Jianjun and Morrison, Alanna C and Ong, Rick Twee-Hee and Papanicolau, George J and Penninx, Brenda W and Psaty, Bruce M and Raffel, Leslie J and Raitakari, Olli T and Rice, Kenneth and Rivadeneira, Fernando and Rose, Lynda M and Sanna, Serena and Scott, Robert A and Siscovick, David S and Uitterlinden, Andre G and Vaidya, Dhananjay and van der Klauw, Melanie M and Vasan, Ramachandran S and Vithana, Eranga Nishanthie and Völker, Uwe and Völzke, Henry and Watkins, Hugh and Young, Terri L and Aung, Tin and Bochud, Murielle and Farrall, Martin and Hartman, Catharina A and Laan, Maris and Lakatta, Edward G and Lehtimäki, Terho and Loos, Ruth J.F and Lucas, Gavin and Meneton, Pierre and Palmer, Lyle J and ... and LifeLines Cohort Study
The American Journal of Human Genetics, ISSN 0002-9297, 07/2014, Volume 95, Issue 1, pp. 24 - 38
Journal Article
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2017, Volume 70, Issue 14, pp. 1732 - 1740
Genetic screening programs in unselected individuals with increased levels of low-density lipoprotein cholesterol (LDL-C) have shown modest results in... 
Dutch Lipid Clinic | cholesterol | genetics | low-density lipoprotein cholesterol | Simon Broome criteria | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | MYOCARDIAL-INFARCTION | GUIDELINES | RISK | PREVALENCE | DENSITY-LIPOPROTEIN CHOLESTEROL | GENERAL-POPULATION | CARDIOVASCULAR-DISEASE | MUTATIONS | Risk Assessment - methods | Prevalence | Prognosis | Humans | Middle Aged | Hyperlipoproteinemia Type II - diagnosis | Male | Genetic Testing - methods | Patient Selection | Cholesterol, LDL - blood | Female | Hyperlipoproteinemia Type II - drug therapy | Multifactorial Inheritance - genetics | Receptors, LDL - genetics | Reproducibility of Results | Acute Coronary Syndrome - epidemiology | Comorbidity | Risk Factors | Proprotein Convertase 9 - genetics | Apolipoprotein B-100 - genetics | Sterol Esterase - genetics | Hyperlipoproteinemia Type II - epidemiology | Spain - epidemiology | Apolipoproteins E - genetics | Acute Coronary Syndrome - diagnosis | Adaptor Proteins, Signal Transducing - genetics | Hypolipidemic Agents - therapeutic use | Acute Coronary Syndrome - prevention & control | Hyperlipoproteinemia Type II - genetics | Care and treatment | Genetic aspects | Hypercholesterolemia | Coronary heart disease | Cardiac patients | Low density lipoproteins | Analysis | Medical genetics | Medical screening | Lipoproteins (low density) | Test procedures | Criteria | Patients | Low density lipoprotein | Cholesterol | Genetic screening | Disease prevention | Algorithms | Apolipoprotein E | Lipoprotein (low density) receptors | Diagnostic systems | Health risk assessment | Acute coronary syndromes | Statins | Index Medicus | Abridged Index Medicus
Journal Article
Atherosclerosis, ISSN 0021-9150, 2012, Volume 222, Issue 2, pp. 456 - 463
Journal Article
Journal Article
by Simino, J and Shi, G and Bis, J.C and Chasman, D.I and Ehret, G.B and Gu, X.J and Guo, X.Q and Hwang, S.J and Sijbrands, E and Smith, A.V and Verwoert, G.C and Bragg-Gresham, J.L and Cadby, G and Chen, P and Cheng, C.Y and Corre, T.G and de Boer, R.A and Goel, A and Johnson, T and Khor, C.C and Lluis-Ganella, C and Luan, J and Lyytikainen, L.P and Nolte, I.M and Sim, X.L and Sober, S and van der Most, P.J and Verweij, N and Zhao, J.H and Amin, N and Boerwinkle, E and Bouchard, C and Dehghan, A and Eiriksdottir, G and Elosua, R and Franco, O.H and Gieger, C and Harris, T.B and Hercberg, S and Hofman, A and James, A.L and Johnson, A.D and Kahonen, M and Khaw, K.T and Kutalik, Z and Larson, M.G and Launer, L.J and Li, G and Liu, J.J and Liu, K and Morrison, A.C and Navis, G and Ong, R.T.H and Papanicolau, G.J and Penninx, B.W and Psaty, B.M and Raffel, L.J and Raitakari, O.T and Rice, K and Rivadeneira, F and Rose, L.M and Sanna, S and Scott, R.A and Siscovick, D.S and Stolk, R.P and Uitterlinden, A. G and Vaidya, D and van der Klauw, M.M and Vasan, R.S and Vithana, E.N and Volker, U and Volzke, H and Watkins, H and Young, T.L and Aung, T and Bochud, M and Farrall, M and Hartman, C.A and Laan, M and Lakatta, E.G and Lehtimaki, T and Loos, R.J.F and Lucas, G and Meneton, P and Palmer, L.J and Rettig, R and Snieder, H and Tai, E.S and Teo, Y.Y and van der Harst, P and Wareham, N.J and Wijmenga, C and Wong, T.Y and Fornage, M and Gudnason, V and Levy, D and Palmas, W and Ridker, P.M and Rotter, J.I and van Duijn, C.M and ...
American Journal of Human Genetics, ISSN 0002-9297, 2014, Volume 95, Issue 1, pp. 24 - 38
Although age-dependent effects on blood pressure (BP) have been reported, they have not been systematically investigated in large-scale genome-wide association... 
Journal Article
REVISTA ESPANOLA DE CARDIOLOGIA, ISSN 0300-8932, 08/2010, Volume 63, Issue 8, pp. 925 - 933
Introduction and objectives. Coronary artery disease (CAD) has a substantial genetic component and, in recent years, a number of genetic variants associated... 
CARDIAC & CARDIOVASCULAR SYSTEMS | SCORE | CARDIOVASCULAR EVENTS | COMMUNITIES | Polymorphisms | Coronary artery disease | LOCUS | ATHEROSCLEROSIS RISK | PREDICTION | WOMEN | IMPACT | CHROMOSOME 9P21.3 | Genetics | Genetic risk | Genetic variants | GENOME-WIDE ASSOCIATION
Journal Article