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Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2017, Volume 23, Issue 15, pp. 3980 - 3993
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 09/2008, Volume 295, Issue 3, pp. 836 - 843
Glucose transport is a highly regulated process and is dependent on a variety of signaling events. Glycogen synthase kinase-3 (GSK-3) has been implicated in... 
S6 kinase | Metabolism | Glycogen synthetase kinase | Cell signaling | Tuberous sclerosis complex | Mammalian target of rapamycin | BINDING PARTNER | glycogen synthetase kinase | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | tuberous sclerosis complex | TUBEROUS-SCLEROSIS-2 TSC2 GENE | DOMINANTLY INHERITED CANCER | CELL-GROWTH | MTOR | CELL BIOLOGY | GLYCOGEN-SYNTHASE KINASE-3-BETA | GAP ACTIVITY | SKELETAL-MUSCLE | mammalian target of rapamycin | cell signaling | metabolism | EKER RAT MODEL | Protein Kinases - metabolism | Phosphorylation | Maleimides - pharmacology | Glucose Transporter Type 1 - metabolism | Glycogen Synthase Kinase 3 beta | RNA, Messenger - metabolism | Transfection | Time Factors | Tumor Suppressor Proteins - genetics | Indoles - pharmacology | Cell Line | Protein Kinases - drug effects | Tumor Suppressor Proteins - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Rats | Glycogen Synthase Kinase 3 - metabolism | Sirolimus - pharmacology | Animals | Glucose Transporter Type 1 - genetics | Glycogen Synthase Kinase 3 - genetics | Signal Transduction - drug effects | Glucose - metabolism | Protein Kinase Inhibitors - pharmacology | TOR Serine-Threonine Kinases | Mutation | Cell growth | Biochemistry | Glucose | Kinases | Cells | Index Medicus | Receptors and Signal Transduction
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0149405 - e0149405
Journal Article
Cancer, ISSN 0008-543X, 03/2017, Volume 123, Issue 6, pp. 1061 - 1070
In a large study, MET gene amplification, Met protein overexpression, or both, as assessed by various assays, are associated with a poor prognosis in... 
fluorescence in situ hybridization | protein overexpression | gastroesophageal adenocarcinoma | selected reaction monitoring mass spectrometry | immunohistochemistry | negative prognostic biomarker | MET tyrosine kinase | gene amplification | PHASE-III | TUMOR-TISSUE | CELL LUNG-CANCER | PROTEIN-LEVELS | THERAPY | ONCOLOGY | GASTRIC-CANCER | PATHWAY | C-MET | DOUBLE-BLIND | PATIENTS PTS | Immunohistochemistry | Stomach Neoplasms - genetics | Gene Expression | Prognosis | Humans | Proportional Hazards Models | In Situ Hybridization, Fluorescence | Biomarkers, Tumor | Proto-Oncogene Proteins c-met - genetics | Gene Amplification | Esophageal Neoplasms - genetics | Mass Spectrometry | Esophageal Neoplasms - mortality | Adenocarcinoma - genetics | Stomach Neoplasms - mortality | Adenocarcinoma - mortality | Tyrosine | Usage | Fluorescence in situ hybridization | Research | Biological markers | Esophageal cancer | Adenocarcinoma | Therapy | Correlation | Copy number | Fluorescence | Decisions | Assaying | c-Met protein | Proteins | Confidence intervals | Water analysis | Protein-tyrosine kinase receptors | Bioindicators | MET protein | Protein-tyrosine kinase | Monitoring | Spectroscopy | Enumeration | Chromosome 7 | Mass spectroscopy | Hazards | Gene expression | Patients | Survival | Amplification | Gene amplification | Medical prognosis | Proteomics | Biomarkers | Sampling methods | Scientific imaging | Mass spectrometry | Tumors | Cancer | Index Medicus | Abridged Index Medicus | Original
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2019, Volume 25, Issue 8, pp. 2403 - 2413
Purpose: This first-in-human, open-label phase I study evaluated AMG 337, an oral, highly selective small-molecule inhibitor of MET in advanced solid tumors.... 
ONCOLOGY | C-MET | DOUBLE-BLIND | PLACEBO PLUS ERLOTINIB | GENE AMPLIFICATION | RECEPTOR | KINASE INHIBITOR | GROWTH-FACTOR | TARGETING MET | COMBINATION | PREVIOUSLY TREATED PATIENTS | Index Medicus
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 11/2018
This first-in-human, open-label phase I study evaluated AMG 337, an oral, highly selective small-molecule inhibitor of MET in advanced solid tumors. Patients... 
Journal Article
JOURNAL OF CLINICAL ONCOLOGY, ISSN 0732-183X, 05/2014, Volume 32, Issue 15, pp. 4048 - 4048
Conference Proceeding