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perioperative care (10) 10
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1. Full Text Improving outcomes with a little EFFORT
by Lobo, Dileep N
The Lancet, ISSN 0140-6736, 06/2019, Volume 393, Issue 10188, pp. 2278 - 2280
The potential importance of these observations was emphasised by a study from the 1990s showing that 30% of 500 patients admitted to hospital for treatment had... 
Elderly people | Intervention | Medical services | Clinical trials | Recovery of function | Risk | Mental depression | Nutritional requirements | Clinical outcomes | Proteins | Motivation | Food quality | Malnutrition | Nutritional status | Food | Medical personnel | Appetite | Gastrointestinal symptoms | Dietitians | Complications | Mortality | Medical treatment | Patients | Discharge | Nutrition research | Hospitals | Mood | Diet | Food intake
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2. Full Text Intraoperative Goal-directed Fluid Therapy in Elective Major Abdominal Surgery: A Meta-analysis of Randomized Controlled Trials
by Rollins, Katie E and Lobo, Dileep N
Annals of Surgery, ISSN 0003-4932, 03/2016, Volume 263, Issue 3, pp. 465 - 476
OBJECTIVES:To compare the effects of intraoperative goal-directed fluid therapy (GDFT) with conventional fluid therapy, and determine whether there was a... 
intraoperative | metaanalysis | Complications | goal-directed fluid therapy | outcome | COLORECTAL SURGERY | SURGERY | complications | CLINICAL-TRIAL | ENHANCED RECOVERY PROTOCOL | HOSPITAL STAY | meta-analysis | PULSE PRESSURE VARIATION | COLONIC RESECTION | BOWEL SURGERY | HEMODYNAMIC THERAPY | STROKE VOLUME | RISK SURGICAL-PATIENTS | Outcome and Process Assessment (Health Care) | Fluid Therapy - methods | Humans | Intraoperative Care | Abdomen - surgery | Randomized Controlled Trials as Topic | Index Medicus | Abridged Index Medicus | Meta-Analyses
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3. Full Text Fragility, Spin, and Interpretation of Randomized Clinical Trials
by Lobo, Dileep N
Critical Care Medicine, ISSN 0090-3493, 03/2019, Volume 47, Issue 3, pp. 486 - 488
fragility index | interpretation | spin | robustness | INDEX | randomized controlled trials | reporting | CRITICAL CARE MEDICINE
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4. Full Text The death of Charlotte Brontë from hyperemesis gravidarum and refeeding syndrome: A new perspective
by Allison, Simon P and Lobo, Dileep N
Clinical Nutrition, ISSN 0261-5614, 2019
Many theories have been advanced concerning the cause of Charlotte Brontë's death, none of which fully explain all the symptoms she experienced in the course... 
Appetite | Hyperemesis gravidarum | Charlotte Brontë | Cause of death | Refeeding syndrome
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5. Full Text Outcomes Following an Index Emergency Admission With Cholecystitis: A National Cohort Study
by Mytton, Jemma and Daliya, Prita and Singh, Pritam and Parsons, Simon L and Lobo, Dileep N and Lilford, Richard and Vohra, Ravinder S
Annals of Surgery, ISSN 0003-4932, 09/2019, p. 1
OBJECTIVE:The objective of this study was to evaluate the differences between patients who undergo cholecystectomy following index admission for cholecystitis,... 
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6. Full Text Intravenous 0.9% saline and general surgical patients: A problem, not a solution
by Lobo, Dileep N
Annals of Surgery, ISSN 0003-4932, 05/2012, Volume 255, Issue 5, pp. 830 - 832
SALT | SURGERY | LACTATED RINGERS SOLUTION | FLUID | METABOLISM | ACID-BASE | INFUSIONS | Sodium Chloride - adverse effects | Digestive System Surgical Procedures | Cardioplegic Solutions - adverse effects | Humans | Sodium Acetate - adverse effects | Potassium Chloride - adverse effects | Gluconates - adverse effects | Magnesium Chloride - adverse effects
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7. Full Text Non-operative management of uncomplicated acute appendicitis in children: where is the evidence?
by Rollins, Katie E and Lobo, Dileep N
Archives of Disease in Childhood, ISSN 0003-9888, 12/2017, Volume 102, Issue 12, pp. 1099 - 1100
[...]in addition to the need for general anaesthetia, there are potential risks and complications associated with the procedure. [...]in children, surgical... 
General paediatrics | Appendicitis | Appendicectomy | Antibiotic therapy | PEDIATRICS | ANTIBIOTICS | METAANALYSIS | APPENDECTOMY | Appendectomy | Systematic review | Appendix | Meta-analysis | Studies | Inflammatory bowel disease | Pain | Antibiotics | Surgery | Surgeons | Adults | Children
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8. Full Text Expert’s comment concerning Grand Rounds Case entitled “pancreatic fracture: a rare complication following scoliosis surgery” by Mélodie Juricic Jr. et al. (Eur Spine J; [2017]: doi: 10.1007/s00586-017-5318-x)
by Bartlett, David C and Lobo, Dileep N
European Spine Journal, ISSN 0940-6719, 9/2018, Volume 27, Issue 9, pp. 2100 - 2101
Medicine & Public Health | Surgical Orthopedics | Neurosurgery | Pancreas | Scoliosis | Spine | Surgery
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9. Full Text The Role of Oral Antibiotic Preparation in Elective Colorectal Surgery: A Meta-analysis
by Rollins, Katie E and Javanmard-Emamghissi, Hannah and Acheson, Austin G and Lobo, Dileep N
Annals of Surgery, ISSN 0003-4932, 07/2019, Volume 270, Issue 1, pp. 43 - 58
OBJECTIVES:To compare the impact of the use of oral antibiotics (OAB) with or without mechanical bowel preparation (MBP) on outcome in elective colorectal... 
SYSTEMIC ANTIBIOTICS | mechanical bowel preparation | RISK-FACTORS | surgical site infection | RANDOMIZED CLINICAL-TRIAL | INTRAVENOUS ANTIMICROBIAL PROPHYLAXIS | colorectal | COLON SURGERY | anastomotic leak | oral antibiotics | ENHANCED RECOVERY | PERIOPERATIVE CARE | surgery | Prevention | Complications and side effects | Usage | Antibiotics | Dosage and administration | Surgical wound infections | Colorectal surgery | Risk factors
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10. Full Text Expert's comment concerning Grand Rounds Case entitled "pancreatic fracture: a rare complication following scoliosis surgery" by Mélodie Juricic Jr. et al. (Eur Spine J; [2017]: doi: 10.1007/s00586-017-5318-x)
by Bartlett, David C and Lobo, Dileep N
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, ISSN 0940-6719, 02/2018, Volume 27, Issue 9
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00586-018-5480-9 
Medicine, Experimental | Medical research | Orthopedic surgery | Scoliosis | Gastrointestinal diseases
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11. Full Text Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials
by Chowdhury, Abeed H and Adiamah, Alfred and Kushairi, Anisa and Varadhan, Krishna K and Krznaric, Zeljko and Kulkarni, Anil D and Neal, Keith R and Lobo, Dileep N
Annals of surgery, ISSN 0003-4932, 08/2019, p. 1
To define the impact of perioperative treatment with probiotics or synbiotics on postoperative outcome in patients undergoing abdominal surgery. Postoperative... 
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12. Full Text Should chloride-rich crystalloids remain the mainstay of fluid resuscitation to prevent ‘pre-renal’ acute kidney injury?: con
by Lobo, Dileep N and Awad, Sherif
Kidney International, ISSN 0085-2538, 12/2014, Volume 86, Issue 6, pp. 1096 - 1105
The high chloride content of 0.9% saline leads to adverse pathophysiological effects in both animals and healthy human volunteers, changes not seen after... 
balanced crystalloids | 0.9% saline | acute kidney injury | hyperchloremic acidosis | intravenous fluids | morbidity | Acute kidney injury | Hyperchloremic acidosis | Balanced crystalloids | Morbidity | Intravenous fluids | SODIUM-CHLORIDE | DIABETIC-KETOACIDOSIS | HYPERCHLOREMIC METABOLIC-ACIDOSIS | NORMAL SALINE | DOUBLE-BLIND CROSSOVER | BLOOD-FLOW | UNCONTROLLED HEMORRHAGIC-SHOCK | LACTATED RINGERS SOLUTION | 0.9-PERCENT SALINE | UROLOGY & NEPHROLOGY | PLASMA-LYTE | Sodium Chloride - adverse effects | Isotonic Solutions - therapeutic use | Resuscitation - methods | Chlorine - blood | Humans | Isotonic Solutions - administration & dosage | Isotonic Solutions - adverse effects | Sodium Chloride - administration & dosage | Acute Kidney Injury - prevention & control | Animals | Isotonic Solutions - chemistry | Fluid Therapy - methods | Potassium - blood | Acute Kidney Injury - chemically induced | Review
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13. Full Text Fluid overload and surgical outcome: Another piece in the jigsaw
by Lobo, Dileep N
Annals of Surgery, ISSN 0003-4932, 02/2009, Volume 249, Issue 2, pp. 186 - 188
SURGERY | TRIAL | RECOVERY | MANAGEMENT | OXYGEN-TENSION | SALINE | RESTRICTION | DOUBLE-BLIND CROSSOVER | TRAUMA RESUSCITATION | Water-Electrolyte Balance - physiology | Animals | Fluid Therapy - methods | Humans | Intestines - surgery | Water-Electrolyte Imbalance - physiopathology | Rats | Water-Electrolyte Imbalance - prevention & control | Anastomosis, Surgical | Water-Electrolyte Imbalance - etiology | Wound Healing - physiology | Fluid Therapy - adverse effects | Index Medicus | Abridged Index Medicus
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14. Full Text Opioid stewardship: a need for opioid discharge guidance. Comment on Br J Anaesth 2019; 122: e198–e208
by Levy, Nicholas and Lobo, Dileep N and Fawcett, William J and Ljungqvist, Olle and Scott, Michael J
British Journal of Anaesthesia, ISSN 0007-0912, 06/2019, Volume 122, Issue 6, pp. e215 - e216
ANESTHESIOLOGY | PAIN | MANAGEMENT | DEPENDENCE
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15. Full Text Pancreas preserving distal duodenectomy: A versatile operation for a range of infra-papillary pathologies
by W Kyle Mitchell Pradeep F Thomas Abed M Zaitoun Adam J Brooks Dileep N Lobo
世界胃肠病学杂志：英文版, ISSN 1007-9327, 2017, Volume 23, Issue 23, pp. 4252 - 4261
AIM To investigate the range of pathologies treated by pancreas preserving distal duodenectomy(PPDD) and present the outcome of follow-up.METHODS Neoplastic... 
Treatment | Duodenal disease | Outcome | Indications | Adults | Duodenojejunostomy | Surgical technique | Pancreas preserving distal duodenectomy | SURGERY | SPARING DUODENECTOMY | 3RD | DUODENAL PATHOLOGY | LEIOMYOSARCOMA | GASTROENTEROLOGY & HEPATOLOGY | Lymph Nodes - pathology | Follow-Up Studies | Humans | Middle Aged | Organ Sparing Treatments | Male | Case-Control Studies | Pancreaticoduodenectomy - methods | Blood Transfusion | Aged, 80 and over | Adult | Female | Duodenal Neoplasms - surgery | Duodenal Neoplasms - pathology | Gastrointestinal Stromal Tumors - surgery | Catheterization | Postoperative Period | Pancreas - pathology | Treatment Outcome | Pancreas - surgery | Duodenoscopy | Algorithms | Duodenum - surgery | Duodenum - pathology | Ampulla of Vater - surgery | Anastomosis, Surgical | Aged | Adenocarcinoma - surgery | Case Control Study
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16. Fluid Management in Abdominal Surgery. What, When, and When Not to Administer
by Raghunathan, Karthik and Singh, Mandeep and Lobo, Dileep N
Anesthesiology Clinics, ISSN 1932-2275, 03/2015, Volume 33, Issue 1, pp. 51 - 64
The entire team (including anesthesiologists, surgeons, and intensive care physicians) must work together (before, during, and after abdominal surgery) to... 
Balanced fluids | Noninvasive monitoring | Colloids | Fluid responsiveness | Crystalloids | Intravenous fluids | Administration, Intravenous | Isotonic Solutions - therapeutic use | Colloids - administration & dosage | Fluid Therapy - methods | Humans | Isotonic Solutions - administration & dosage | Perioperative Care - methods | Colloids - therapeutic use | Abdomen - surgery
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17. Full Text Response to Dr Hahn, ANNSURG-D-12-01545
by Chowdhury, Abeed H and Lobo, Dileep N and Cox, Eleanor F and Francis, Susan T
Annals of Surgery, ISSN 0003-4932, 10/2015, p. 1
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18. Full Text (Ab)normal saline and physiological Hartmann's solution: A randomized double-blind crossover study
by Reid, Fiona and Lobo, Dileep N and Williams, Robert N and Rowlands, Brian J and Allison, Simon P
Clinical Science, ISSN 0143-5221, 01/2003, Volume 104, Issue 1, pp. 17 - 24
In this double-blind crossover study, the effects of bolus infusions of 0.9% saline (NaCl) and Hartmann's solution on serum albumin, haematocrit and serum and... 
Water | Dilution | Albumin | Electrolytes | Hartmann's solution | Sodium chloride | Crossover study | Crystalloids | crossover study | MEDICINE, RESEARCH & EXPERIMENTAL | LACTATED RINGERS | SODIUM-CHLORIDE | VOLUNTEERS | crystalloids | HYPERCHLOREMIC METABOLIC-ACIDOSIS | INFUSION | electrolytes | water | BASE | PLASMA | dilution | albumin | 0.9-PERCENT SALINE | ANION GAP | sodium chloride | Isotonic Solutions - pharmacology | Double-Blind Method | Natriuresis - drug effects | Sodium Chloride - pharmacology | Humans | Hematocrit | Body Weight - drug effects | Male | Urea - blood | Sodium - blood | Cross-Over Studies | Osmolar Concentration | Fluid Therapy - methods | Sodium Chloride - pharmacokinetics | Urination - drug effects | Adult | Potassium - blood | Isotonic Solutions - pharmacokinetics | Serum Albumin - metabolism
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19. Full Text A meta-analysis of randomised controlled trials of intravenous fluid therapy in major elective open abdominal surgery: getting the balance right
by Varadhan, Krishna K and Lobo, Dileep N
Proceedings of the Nutrition Society, ISSN 0029-6651, 11/2010, Volume 69, Issue 4, pp. 488 - 498
The terminology used for describing intervention groups in randomised controlled trials (RCT) on the effect of intravenous fluid on outcome in abdominal... 
Restriction | Overload | Outcome | Crystalloid | Fluid therapy | Saline | Peri-operative | Meta-analysis | COLORECTAL SURGERY | OXYGEN-TENSION | DOUBLE-BLIND CROSSOVER | TRAUMA RESUSCITATION | RECOVERY | NUTRITION & DIETETICS | 0.9-PERCENT SALINE | COMPLICATIONS | PERIOPERATIVE FLUID | CHLORIDE | Fluid Therapy | Length of Stay | Digestive System Surgical Procedures | Humans | Terminology as Topic | Water-Electrolyte Balance | Infusions, Intravenous - methods | Postoperative Complications | Abdomen - surgery | Elective Surgical Procedures | Randomized Controlled Trials as Topic
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20. Full Text A randomized, controlled, double-blind crossover study on the effects of 2-L infusions of 0.9% saline and plasma-lyte® 148 on renal blood flow velocity and renal cortical tissue perfusion in healthy volunteers
by Chowdhury, Abeed H and Cox, Eleanor F and Francis, Susan T and Lobo, Dileep N
Annals of Surgery, ISSN 0003-4932, 07/2012, Volume 256, Issue 1, pp. 18 - 24
Objective: We compared the effects of intravenous infusions of 0.9% saline ([Cl-] 154 mmol/L) and Plasma-Lyte 148 ([Cl-] 98 mmol/L, Baxter Healthcare) on renal... 
KIDNEYS | SURGERY | RESPONSES | LACTATED RINGERS SOLUTION | SODIUM-CHLORIDE | PLASMA | RENIN | CONTRACTION | HYPERCHLOREMIA | GLOMERULAR-FILTRATION RATE | MACULA DENSA | Double-Blind Method | Sodium Chloride - pharmacology | Humans | Sodium Acetate - pharmacology | Cardioplegic Solutions - pharmacology | Male | Gluconates - pharmacology | Kidney | Cross-Over Studies | Young Adult | Magnetic Resonance Imaging | Magnesium Chloride - pharmacology | Potassium Chloride - pharmacology | Adult | Infusions, Intravenous | Blood Flow Velocity - drug effects
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