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Journal of the International AIDS Society, ISSN 1758-2652, 07/2016, Volume 19, Issue 6 Suppl 5, pp. 21264 - n/a
Journal Article
by Kim, J and Kim, YJ and Londhe, AM and Pae, AN and Choo, H and Kim, HJ and Min, SJ
MOLECULES, ISSN 1420-3049, 09/2019, Volume 24, Issue 18, p. 3234
Here, we describe the synthesis of disubstituted pyrimidine derivatives and their biological evaluation as selective 5-HT2C agonists. To improve selectivity... 
binding affinity | selectivity | IN-VITRO | DESIGN | cell-based assay | RECEPTOR AGONISTS | BEHAVIOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | disubstituted pyrimidine | 5-HT2C receptor | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2017, Volume 141, pp. 657 - 675
Tyrosine kinases including LCK and FMS are involved in inflammatory disorders as well as many types of cancer. Our team has designed and synthesized thirty... 
Inflammation | Synthesis | LCK | FMS | Molecular docking and RAW 264.7 macrophages | CHEMISTRY, MEDICINAL | COLONY-STIMULATING FACTORS | ORGAN ALLOGRAFT-REJECTION | TYROSINE KINASE | LYMPHOCYTE-SPECIFIC KINASE | ACUTE MYELOID-LEUKEMIA | SRC-FAMILY KINASES | SIGNAL-TRANSDUCTION | macrophages | ORALLY-ACTIVE INHIBITORS | IN-VIVO | Molecular docking and RAW 264.7 | VIVO ANTIINFLAMMATORY ACTIVITY | Cell Survival - drug effects | Protein Kinase Inhibitors - chemical synthesis | Pyrimidines - chemical synthesis | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - metabolism | Structure-Activity Relationship | Pyrimidines - pharmacology | Pyrimidines - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Dose-Response Relationship, Drug | Lymphocyte Specific Protein Tyrosine Kinase p56(lck) - antagonists & inhibitors | Arthritis, Rheumatoid - metabolism | Inflammation - metabolism | Protein Kinase Inhibitors - chemistry | Receptors, Colony-Stimulating Factor - antagonists & inhibitors | Animals | Arthritis, Rheumatoid - drug therapy | Inflammation - drug therapy | RAW 264.7 Cells | Mice | Molecular Docking Simulation | Molecular Structure | Protein Kinase Inhibitors - pharmacology | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis | Schiff bases | Rheumatoid factor | Care and treatment | Arthritis | Macrophages | Analysis
Journal Article
American Journal of Orthodontics & Dentofacial Orthopedics, ISSN 0889-5406, 02/2019, Volume 155, Issue 2, pp. 207 - 215
The aim of this study was to evaluate the stability of pharyngeal airway space changes with the use of acoustic pharyngometry 1 year after bilateral sagittal... 
BIMAXILLARY SURGERY | ORTHOGNATHIC SURGERY | STABILITY | DENTISTRY, ORAL SURGERY & MEDICINE | VOLUME | MAXILLARY | BEAM COMPUTED-TOMOGRAPHY
Journal Article
Journal Article
Journal of Computer-Aided Molecular Design, ISSN 0920-654X, 10/2017, Volume 31, Issue 10, pp. 929 - 941
Journal Article
Journal of Computer-Aided Molecular Design, ISSN 0920-654X, 10/2017, Volume 31, Issue 10, pp. 877 - 889
ERG-associated protein with the SET domain (ESET/SET domain bifurcated 1/SETDB1/KMT1E) is a histone lysine methyltransferase (HKMT) and it preferentially... 
Trimethylated H3K9 (H3K9me3) | Chemistry | Physical Chemistry | Homology modeling | Peptide-competitive small molecule inhibitors | Virtual screening | Huntington’s disease | Animal Anatomy / Morphology / Histology | Pharmacophore | SETDB1/ESET | Computer Applications in Chemistry | METHYLTRANSFERASE | CHROMATIN-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | Huntington's disease | G9A | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | BIOPHYSICS | ALIGNMENT | LYSINE METHYLATION | HETEROCHROMATIN | INHIBITOR | ESET | EXPRESSION | Cell Line | Cell Survival | Humans | Neurons - cytology | Structure-Activity Relationship | Protein Methyltransferases - antagonists & inhibitors | Protein Methyltransferases - metabolism | Databases, Pharmaceutical | Histone-Lysine N-Methyltransferase - metabolism | Computer Simulation | Protein Binding | Ligands | Molecular Docking Simulation | Histones - metabolism | Benzene Derivatives - chemistry | Methylation | Neurons - drug effects | Binding Sites | Benzene Derivatives - pharmacology | Medical research | Epigenetic inheritance | Nervous system diseases | Peptides | Lysine | Analysis | Medicine, Experimental | Development and progression | Genetic engineering | Drug discovery | Investigations | Evaluation | Molecular structure | Toxicity | Disorders | Homology | Cytotoxicity | Bifurcations | Pharmacology | Lead compounds | Inhibitors | Epigenetics | Pharmaceutical sciences
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 12/2017, Volume 141, pp. 240 - 256
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 09/2016, Volume 9, Issue 5, pp. 704 - 712
Seventeen (E)-1-(8-hydroxyquinolin-7-yl)-3-phenylprop-2-en-1 one derivatives were synthesized via aldol condensation of substituted benzaldehydes with... 
Quinoline | Anti-asthmatic | Docking | Cyclooxygenase | Analgesic | Phosphodiesterase | PIPERINE | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
by Park, JH and Ju, YH and Choi, JW and Song, HJ and Jang, BK and Woo, J and Chun, H and Kim, HJ and Shin, SJ and Yarishkin, O and Jo, S and Park, M and Yeon, SK and Kim, S and Kim, J and Nam, MH and Londhe, AM and Cho, SJ and Cho, S and Lee, C and Hwang, SY and Kim, SW and Oh, SJ and Cho, J and Pae, AN and Lee, CJ and Park, KD
SCIENCE ADVANCES, ISSN 2375-2548, 03/2019, Volume 5, Issue 3, p. eaav0316
Monoamine oxidase-B (MAO-B) has recently emerged as a potential therapeutic target for Alzheimer's disease (AD) because of its association with aberrant... 
MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | GABA | SELEGILINE | L-DEPRENYL | UPDATE | ASTROCYTES | BRAIN
Journal Article
01/2004, ISBN 9788190210911, Volume 2
The knowledge of tide prediction is very much essential in effective planning and implementation of projects related to coastal and harbor engineering... 
Book Chapter
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2018, Volume 197, Issue 2, pp. 272 - 272
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2002, Volume 110, Issue 11, pp. 1703 - 1716
Mortality related to adult respiratory distress syndrome (ARDS) ranges from 35% to 65%. Lung-protective ventilator strategies can reduce mortality during ARDS.... 
Receptors, Interleukin-8B - physiology | Lung - pathology | Phosphorylation | Animals | Peroxidase - analysis | Respiration, Artificial - adverse effects | Humans | Chemokines, CXC - physiology | Ligands | Models, Animal | Lung Injury | Mice
Journal Article
Medical Journal Armed Forces India, ISSN 0377-1237, 01/2017, Volume 73, Issue 1, pp. 65 - 73
Nonsurgical correction of deep bite involves either extrusion of posterior teeth, intrusion of incisors, or combination of both. The introduction of skeletal... 
Microimplants | Intrusion | Skeletal anchorage device (SAD) | Connecticut intrusion arches (CIA) | Deep bite | Original
Journal Article
Beilstein Journal of Organic Chemistry, ISSN 1860-5397, 12/2017, Volume 13, Issue 1, pp. 2895 - 2901
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2014, Volume 111, Issue 12, pp. 4525 - 4529
Journal Article
Journal of medical systems, 12/2016, Volume 40, Issue 12, p. 279
Ultrasound with harmonics has emerged as an exceptional alternative to competitively low resolution fundamental ultrasound imaging. The use of second harmonic... 
Transducers | Humans | Image Enhancement - methods | Ultrasonography - methods
Journal Article