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Journal Article
Journal of Oncology, ISSN 1687-8450, 11/2019, Volume 2019, pp. 1 - 2
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 114, Issue 10, pp. 2159 - 2167
Journal Article
Frontiers in Pediatrics, ISSN 2296-2360, 11/2019, Volume 7
Acute myeloid leukemia (AML) is a hematopoietic disorder characterized by numerous cytogenetic and molecular aberrations that accounts for ~25% of childhood... 
Pediatrics | targeted therapy | FLT-3 inhibitors | Pediatric AML | Hedgehog pathway inhibitors | DOT1L inhibitors
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 66, pp. 109915 - 109923
L-Asparaginase (L-Asp) is an enzyme that catalyzes the hydrolysis of L-asparagine to L-aspartic acid, and its depletion induces leukemic cell death. L-Asp is... 
ASNS gene | Monosomy chromosome 7 | Acute myeloid leukemia | L-Asparaginase | CELLS | METHYLATION | MONOSOMY-7 | monosomy chromosome 7 | DRUG-RESISTANCE | CHILDREN | CELL BIOLOGY | TRIAL | IN-VITRO | THERAPY | acute myeloid leukemia | ACUTE LYMPHOBLASTIC-LEUKEMIA
Journal Article
JOURNAL OF ONCOLOGY, ISSN 1687-8450, 07/2019, Volume 2019, pp. 7239206 - 36
The last two decades of genome-scale research revealed a complex molecular picture of acute myeloid leukemia (AML). On the one hand, a number of mutations were... 
GENE-EXPRESSION SIGNATURE | BONE-MARROW MICROENVIRONMENT | MESSENGER-RNA | ONCOLOGY | ACUTE MYELOGENOUS LEUKEMIA | HEMATOPOIETIC STEM-CELLS | DNA MICROARRAY ANALYSIS | DISTINCT GENE | NUCLEOPHOSMIN NPMC(+) AML | RNA-SEQ ANALYSIS | MICRORNA EXPRESSION | RNA | Oncology, Experimental | Genes | Genomics | Genomes | Research | Gene expression | Health aspects | Biotechnology industry | Cancer
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 05/2016, Volume 1368, pp. 143 - 159
Genetic variations in patients have strong impact on their drug therapies and responses because the variations may contribute to the efficacy and/or produce... 
Drug metabolizing enzymes and transporters | Single nucleotide polymorphisms | DNA - genetics | DNA - isolation & purification | Pharmacogenetics - methods | Genetic Markers - genetics | Staining and Labeling | Polymorphism, Single Nucleotide | Software | Statistics as Topic | Nucleic Acid Amplification Techniques
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40934
Journal Article
Advances in Biological Regulation, ISSN 2212-4926, 12/2019, Volume 74, p. 100649
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disorder characterized by malignant transformation of immature progenitors primed towards T-cell... 
Mutations | Cell signaling pathways | Drug-resistance | Metabolism | Target therapies
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 03/2016, Volume 1863, Issue 3, pp. 449 - 463
Journal Article