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Nucleic Acids Research, ISSN 0305-1048, 11/2016, Volume 44, Issue 19, pp. e147 - e147
Genome assemblies that are accurate, complete and contiguous are essential for identifying important structural and functional elements of genomes and for... 
MOLECULE SEQUENCING READS | QUALITY | MICROBIAL GENOMES | HYBRID ERROR-CORRECTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DROSOPHILA | Cell Line | Computational Biology - methods | Animals | Humans | High-Throughput Nucleotide Sequencing | Genome | Genomics - methods | Drosophila melanogaster - genetics | Sequence Analysis, DNA | Methods Online
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 10/2019, Volume 10, Issue 1, pp. 1 - 11
It has been hypothesized that individually-rare hidden structural variants (SVs) could account for a significant fraction of variation in complex traits. Here... 
GENETIC-VARIATION | FUNCTIONAL ELEMENTS | POPULATION | DNA | MULTIDISCIPLINARY SCIENCES | NATURAL-SELECTION | MUTATION | LIFE-HISTORY | MISSING HERITABILITY | DROSOPHILA INSULIN-RECEPTOR | MELANOGASTER | Quantitative trait loci | Heterogeneity | Phenotypes | Insects | Genotyping | Gene frequency | Drosophila | Genes | Alleles | Amino acids | Genomes | Gene mapping
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 11/2019, Volume 9, Issue 1, pp. 1 - 13
The cricetine rodents Peromyscus leucopus and P. maniculatus are key reservoirs for several zoonotic diseases in North America. We determined the complete... 
BORRELIA-BURGDORFERI | SPP | EVOLUTION | RNA-SEQ | MULTIDISCIPLINARY SCIENCES | RESISTANCE | POPULATIONS | INFECTION | MICE | COMPETENCE | ASSOCIATION
Journal Article
JOURNAL OF NEUROSCIENCE, ISSN 0270-6474, 11/2019, Volume 39, Issue 47, pp. 9453 - 9464
Seizures are common in humans with various etiologies ranging from congenital aberrations to acute injuries that alter the normal balance of brain excitation... 
DEFICIENCY LEADS | STEM-CELLS | ACTIVATION | MOSSY FIBER | immature projections | ADULT NEUROGENESIS | SPINAL MICROGLIA | CULTURED NEURONS | NEUROSCIENCES | P2Y12R | neurogenesis | ANIMAL-MODELS | seizures | INFLAMMATORY CYTOKINES | microglia | HIPPOCAMPAL NEUROGENESIS
Journal Article
MOLECULAR BRAIN, ISSN 1756-6606, 08/2019, Volume 12, Issue 1, pp. 71 - 10
The P2Y12 receptor (P2Y12R) is a purinoceptor that is selectively expressed in microglia in the central nervous system. As a signature receptor, microglial... 
CELLS | ACTIVATION | BEHAVIOR | SPINAL MICROGLIA | GATE | NEUROSCIENCES | Microglia | PAIN | P2Y | SURVEILLANCE | Conditional knockout | Innate fear | Anxiety | NEURAL CIRCUITS | MUTATIONS | Hippocampus | Neurons | Nervous system diseases | Batteries | P2Y12 receptors
Journal Article
PLoS genetics, ISSN 1553-7390, 01/2017, Volume 13, Issue 1, p. e1006573
The genetic component of complex disease risk in humans remains largely unexplained. A corollary is that the allelic spectrum of genetic variants contributing... 
Genetic Predisposition to Disease | Phenotype | Epistasis, Genetic | Gene Frequency | Humans | Genotype | Heterozygote | Models, Genetic | Polymorphism, Single Nucleotide | Genome, Human | Genome-Wide Association Study - standards | Genome-wide association studies | Usage | Heterozygosis | Research | Analysis | Heterozygosity
Journal Article
Genetics, ISSN 0016-6731, 01/2015, Volume 199, Issue 1, pp. 85 - 93
Journal Article
Genetics, ISSN 0016-6731, 01/2015, Volume 199, Issue 1, pp. 85 - 85
Transposable elements are a common source of genetic variation that may play a substantial role in contributing to gene expression variation. However, the... 
Journal Article
PLoS Genetics, ISSN 1553-7390, 11/2015, Volume 11, Issue 11
  Natural populations exhibit a great deal of interindividual genetic variation in the response to toxins, exemplified by the variable clinical efficacy of... 
Cytochrome | Genotype & phenotype | Enzymes | Insects | Pesticides | Population | Toxins | Gene expression | Caffeine
Journal Article
Molecular Biology and Evolution, ISSN 0737-4038, 12/2014, Volume 31, Issue 12, p. 3228
  In "evolve-and-resequence" (E&R) experiments, whole-genome sequence data from laboratory-evolved populations can potentially uncover mechanisms of adaptive... 
Eukaryotes | Yeast | Genetics | Evolution | Experiments
Journal Article
Molecular Ecology, ISSN 0962-1083, 10/2012, Volume 21, Issue 20, p. 4913
  Combining experimental evolution with whole-genome resequencing is a promising new strategy for investigating the dynamics of evolutionary change. Published... 
Evolutionary biology | Insects | Genomics | Genetic diversity | Population genetics
Journal Article
Clinical Infectious Diseases, ISSN 1058-4838, 10/2016, Volume 63, Issue 8, p. 999
  Background. Respiratory viral infections (RVIs) are frequent complications of hematopoietic stem cell transplant (HSCT). Surgical masks are a simple and... 
Transplants & implants | Risk assessment | Stem cells | Nosocomial infections | Viral infections
Journal Article
Genetics, ISSN 0016-6731, 09/2014, Volume 198, Issue 1, pp. 31 - 31
The severity of the toxic side effects of chemotherapy shows a great deal of interindividual variability, and much of this variation is likely genetically... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2001, Volume 276, Issue 23, pp. 19937 - 19944
We describe statistical methods based on the t test that can be conveniently used on high density array data to test for statistically significant differences... 
CDNA FILTER ANALYSIS | PATTERNS | SCALE | QUANTITATIVE HYBRIDIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ARRAYS | Genes, Bacterial | Gene Expression Profiling | Oligonucleotide Array Sequence Analysis | Escherichia coli - genetics | Bayes Theorem
Journal Article
Molecular Biology and Evolution, ISSN 0737-4038, 04/2014, Volume 31, Issue 4, p. 1040
  A novel approach for dissecting complex traits is to experimentally evolve laboratory populations under a controlled environment shift, resequence the... 
Haplotypes | Simulation | Genomics | Polymorphism
Journal Article
Genetics, ISSN 0016-6731, 09/2014, Volume 198, Issue 1, pp. 45 - 45
Animals in nature are frequently challenged by toxic compounds, from those that occur naturally in plants as a defense against herbivory, to pesticides used to... 
Journal Article
by James, Spencer L and Abate, Kalkidan Hassen and Abate, Degu and Abay, Solomon M and Abbafati, Cristiana and Abbasi, Nooshin and Abbastabar, Hedayat and Abd-Allah, Foad and Abdela, Jemal and Abdelalim, Ahmed and Abdollahpour, Ibrahim and Abdulkader, Rizwan Suliankatchi and Abebe, Zegeye and Abera, Semaw F and Abil, Olifan Zewdie and Abraha, Haftom Niguse and Abu-Raddad, Laith Jamal and Abu-Rmeileh, Niveen M E and Accrombessi, Manfred Mario Kokou and Acharya, Dilaram and Acharya, Pawan and Ackerman, Ilana N and Adamu, Abdu A and Adebayo, Oladimeji M and Adekanmbi, Victor and Adetokunboh, Olatunji O and Adib, Mina G and Adsuar, Jose C and Afanvi, Kossivi Agbelenko and Afarideh, Mohsen and Afshin, Ashkan and Agarwal, Gina and Agesa, Kareha M and Aggarwal, Rakesh and Aghayan, Sargis Aghasi and Agrawal, Sutapa and Ahmadi, Mehdi and Ahmadi, Alireza and Ahmadieh, Hamid and Ahmed, Muktar Beshir and Aichour, Ibtihel and Aichour, Miloud Taki Eddine and Aichour, Amani Nidhal and Akinyemiju, Tomi and Akseer, Nadia and Al-Aly, Ziyad and Al-Eyadhy, Ayman and Al-Mekhlafi, Hesham M and Al-Raddadi, Rajaa M and Alahdab, Fares and Alam, Tahiya and Alam, Khurshid and Alashi, Alaa and Alavian, Seyed Moayed and Alene, Kefyalew Addis and Alijanzadeh, Mehran and Alizadeh-Navaei, Reza and Aljunid, Syed Mohamed and Alkerwi, Ala'a and Alla, François and Allebeck, Peter and Alouani, Mohamed M L and Altirkawi, Khalid and Alvis-Guzman, Nelson and Amare, Azmeraw T and Aminde, Leopold N and Ammar, Walid and Amoako, Yaw Ampem and Anber, Nahla Hamed and Andrei, Catalina Liliana and Androudi, Sofia and Animut, Megbaru Debalkie and Anjomshoa, Mina and Ansha, Mustafa Geleto and Antonio, Carl Abelardo T and Anwari, Palwasha and Arabloo, Jalal and Arauz, Antonio and Aremu, Olatunde and Ariani, Filippo and Armoon, Bahroom and Ärnlöv, Johan and Arora, Amit and Artaman, Al and Aryal, Krishna K and Asayesh, Hamid and Asghar, Rana Jawad and Ataro, Zerihun and Atre, Sachin R and Ausloos, Marcel and Avila-Burgos, Leticia and Avokpaho, Euripide F G A and Awasthi, Ashish and Ayala Quintanilla, Beatriz Paulina and Ayer, Rakesh and Azzopardi, Peter S and Babazadeh, Arefeh and Badali, Hamid and Badawi, Alaa and Bali, Ayele Geleto and ... and GBD 2017 Dis Injury Incidence Pr and GBD 2017 Disease and Injury Incidence and Prevalence Collaborators and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
The Lancet, ISSN 0140-6736, 11/2018, Volume 392, Issue 10159, pp. 1789 - 1858
The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived... 
no | WOMEN | MEDICINE, GENERAL & INTERNAL | DEMENTIA | VISION IMPAIRMENT | HOSPITAL CARDIAC-ARREST | INFLUENZA VACCINATION | OXYGEN-THERAPY | MATERNAL MORTALITY | HEPATITIS-C | ECONOMIC BURDEN | CHILDREN | Age Distribution | Prevalence | Global Burden of Disease - statistics & numerical data | Humans | Middle Aged | Child, Preschool | Infant | Male | Wounds and Injuries - epidemiology | Socioeconomic Factors | Incidence | Young Adult | Life Expectancy | Global Health - trends | Global Health - statistics & numerical data | Aged, 80 and over | Adult | Disabled Persons - statistics & numerical data | Female | Child | Infant, Newborn | Morbidity - trends | Wounds and Injuries - mortality | Global Burden of Disease - trends | Adolescent | Sex Distribution | Aged | Low back pain | Disorders | Mental depression | Males | Risk factors | Tropical diseases | Hepatitis | Acquired immune deficiency syndrome--AIDS | Fertility | Aging | Injury analysis | Nutrient deficiency | Violence | Anemia | Mortality | Regression analysis | Weight | Diseases | Studies | Charities | Domains | Substance use | Tuberculosis | Diet | Poisoning | Bayesian analysis | Headache | Mental disorders | Iron | Heterogeneity | Demographics | Pain | Remission | Mathematical models | Trends | Injuries | Age | Self-injury | Complications | Health | Aggression | Health risks | Fatal | Estimates | Life span | Kidney diseases | Diabetes | Females | Cancer | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
Journal Article