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Biochemical Society Symposium, ISSN 0067-8694, 06/2013, Volume 41, Issue 3, pp. 727 - 740
Vertebrate DNA can be chemically modified by methylation of the 5 position of the cytosine base in the context of CpG dinucleotides. This modification creates... 
DNA methylation | Epigenetics | DNA demethylation | Chromatin | Transcription | CpG island | transcription | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING-PROTEIN | TRANSCRIPTIONAL REPRESSION | chromatin | H3-LYS METHYLTRANSFERASE COMPLEX | epigenetics | FINGER PROTEIN-1 | EMBRYONIC STEM-CELLS | MIXED-LINEAGE-LEUKEMIA | GENOME-WIDE ANALYSIS | POSTNATAL-DEVELOPMENT | HISTONE H3 ACETYLATION | Amino Acid Sequence | Chromatin - metabolism | DNA-Binding Proteins - physiology | Humans | Models, Molecular | Molecular Sequence Data | DNA Methylation - genetics | Protein Structure, Tertiary - genetics | DNA - metabolism | CpG Islands - physiology | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | CpG Islands - genetics | Zinc Fingers - genetics | DNA Methylation - physiology | Protein Binding - physiology | MBD, methyl-CpG-binding domain | PRC, polycomb group repressive complex | IDAX, inhibition of the Dvl and axin complex protein | ESC, embryonic stem cell | RING, really interesting new gene | CFP1, CxxC finger protein 1 | JmjC, Jumonji C | PHD, plant homeodomain | Biochemical Society Annual Symposium No. 80 | 5mC, 5-methylcytosine | CGBP, CpG-binding protein | 5hmC, 5-hydroxymethylcytosine | DNMT1, DNA methyltransferase 1 | FBXL19, F-box and leucine-rich repeat protein 19 | RFTS, replication foci-targeting sequence | WDR, WD40 repeat | DPY-30, dosage compensation protein 30 | AF9, ALL1–fused gene from chromosome 9 protein | ChIP-seq, chromatin immunoprecipitation sequencing | HDAC, histone deacetylase | YY1, Yin and Yang 1 | RbBP5, retinoblastoma-binding protein 5 | ZF-CxxC, zinc finger-CxxC | BAH, bromo-adjacent homology | ASH2L, absent, small or homeotic 2-like | SETD1, SET domain 1 | TET, ten-eleven translocation | SEC, super-elongation complex | MLL, mixed lineage leukaemia protein | CGI, CpG island | ENL, eleven-nineteen leukaemia | shRNA, short hairpin RNA | KDM, lysine demethylase | RNAPII, RNA polymerase II
Journal Article
Cell, ISSN 0092-8674, 06/2014, Volume 157, Issue 6, pp. 1445 - 1459
Journal Article
Cell, ISSN 0092-8674, 09/2019, Volume 178, Issue 6, pp. 1421 - 1436.e24
Journal Article
Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7339, pp. 518 - 522
Melanoma is a tumour of transformed melanocytes, which are originally derived from the embryonic neural crest. It is unknown to what extent the programs that... 
CELLS | ZEBRAFISH | GENE | MULTIDISCIPLINARY SCIENCES | KINASE | CARBAMOYL-PHOSPHATE SYNTHETASE | INHIBITOR | LEFLUNOMIDE | EXPRESSION | DISCOVERY | Transcription, Genetic - drug effects | Humans | Neural Crest - pathology | Gene Expression Regulation, Neoplastic | Melanoma - enzymology | Stem Cells - cytology | Zebrafish - embryology | Cell Lineage - drug effects | Oxidoreductases Acting on CH-CH Group Donors - antagonists & inhibitors | Neural Crest - metabolism | Melanoma - genetics | Neural Crest - enzymology | Proto-Oncogene Proteins B-raf - metabolism | Disease Models, Animal | Proto-Oncogene Proteins B-raf - chemistry | Animals, Genetically Modified | Rats | Genes, p53 - genetics | Melanoma - pathology | Zebrafish - genetics | Neural Crest - drug effects | Isoxazoles - pharmacology | Oxidoreductases Acting on CH-CH Group Donors - metabolism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Transcription, Genetic - physiology | Animals | Cell Differentiation - drug effects | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Cell Line, Tumor | Stem Cells - drug effects | Stem Cells - pathology | Mice | Isoxazoles - therapeutic use | Amino Acid Substitution | Care and treatment | Gene mutations | Melanoma | Physiological aspects | Genetic aspects | Research | Tumor proteins | Health aspects | Risk factors | Mutation | Gene expression | Chemicals | Stem cells | Tumors
Journal Article
Journal Article