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2003, 2. Aufl., Blackwell handbooks in linguistics, ISBN 9781405132817, Volume 14., ix, 888
The Handbook of Second Language Acquisitionpresents an integrated discussion of key, and sometimes controversial, issues in second language acquisition... 
Second language acquisition
Book
中国电化教育, ISSN 1006-9860, 2017, Issue 5, pp. 73 - 79
Journal Article
by 王赛 and 杨明 and 王佩 and 黄龙江
化学与生物工程, ISSN 1672-5425, 2017, Volume 34, Issue 3, pp. 27 - 30
TQ463;... 
Journal Article
Xiàndài huàgōng, ISSN 0253-4320, 2017, Volume 37, Issue 12, pp. 153 - 157
TQ031.2%TQ032.42; 设计合成了一类多氢键供体的硫脲类小分子催化剂.该催化剂对丙二腈与硝基苯乙烯的不对称Michael加成反应具有一定的催化性能,收率可达79%,ee值为11%.该催化剂在催化不对称Michael加成反应时表现出酶催化的特性,对反应底物具有一定的专一性,且催化剂中手性中心构型一致时才具有... 
Journal Article
by Sokolov, Artem and Gentles, Andrew J and Burzykowski, Tomasz and Poisson, Laila and Weinstein, John N and Huelsken, Joerg and Omberg, Larsson and Colaprico, Antonio and Czerwińska, Patrycja and Mazurek, Sylwia and Krasnitz, Alex and Godwin, Andrew K and Lazar, Alexander J and Stuart, Joshua M and Hoadley, Katherine A and Laird, Peter W and Noushmehr, Houtan and Wiznerowicz, Maciej and Demchok, John A and Kasapi, Melpomeni and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Chudamani, Sudha and Liu, Jia and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Getz, Gad and Heiman, David I and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Zhang, Hailei and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Liu, Yuexin and Miller, Michael and Reynolds, Sheila and Thorsson, Vesteinn and Zhang, Wei and Hegde, Apurva M and Ju, Zhenlin and Korkut, Anil and Li, Jun and Ling, Shiyun and Liu, Wenbin and Lu, Yiling and Mills, Gordon B and Abeshouse, Adam and Chakravarty, Debyani and Chatila, Walid K and de Bruijn, Ino and Gao, Jianjiong and Gross, Benjamin E and Heins, Zachary J and Kundra, Ritika and La, Konnor and Ladanyi, Marc and Luna, Augustin and Nissan, Moriah G and Ochoa, Angelica and Sander, Chris and Sun, Yichao and Zhang, Hongxin and Anur, Pavana and Peto, Myron and Spellman, Paul and Benz, Christopher and Yau, Christina and Hayes, D. Neil and Parker, Joel S and Balasundaram, Miruna and Bowlby, Reanne and Brooks, Denise and Carlsen, Rebecca and Dhalla, Noreen and Holt, Robert and Jones, Steven J.M and Kasaian, Katayoon and Lee, Darlene and Ma, Yussanne and Mayo, Michael and Mungall, Andrew J and Mungall, Karen and ... and The Cancer Genome Atlas Research Network and Cancer Genome Atlas Res Network
Cell (Cambridge), ISSN 0092-8674, 04/2018, Volume 173, Issue 2, pp. 338 - 354.e15
Cancer progression involves the gradual loss of a differentiated phenotype and acquisition of progenitor and stem-cell-like features. Here, we provide novel... 
pan-cancer | genomic | stemness | epigenomic | dedifferentiation | cancer stem cells | machine learning | The Cancer Genome Atlas | Biochemistry, Genetics and Molecular Biology(all) | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
Journal Article
Organic letters, ISSN 1523-7060, 05/2014, Volume 16, Issue 9, pp. 2438 - 2441
Application of indolin-3-one derivatives in a cascade reaction for efficient assembly of complex molecules is a much less explored research area. It is... 
Piperidines - chemistry | Magnetic Resonance Spectroscopy | Stereoisomerism | Indoles - chemical synthesis | Molecular Structure | Catalysis | Piperidines - chemical synthesis | Indoles - chemistry | Index Medicus
Journal Article
by 刘玉龙 and 李华 and 王谢 and 何炜
He cheng hua xue, ISSN 1005-1511, 2013, Volume 21, Issue 3, pp. 272 - 275
O623.736%O623.627; 奎宁和手性氨基醇通过硫脲片段组合,合成了4个新型的具有多氢键供体的双功能手性硫脲类小分子催化剂(5a-5d),其结构经1H NMR,13C NMR,IR和HR-MS表征.以查尔酮为底物,硝基甲烷为亲核试剂,考察了5a ~ 5d在Michael加成反应中的催化活性和对映选择性.结果... 
Journal Article
2017
...原位生成的亚胺离子,这样就大大提高了反应中亚胺离子的活性和浓度。许多传统亚胺离子催化不能实现或者很难实现的反应,在这个催化体系下就可以实现,而且可以降低昂贵的手性催化剂用量,提高反应速率。本论文围绕超分子亚胺离子催化展开,讲述超分子亚胺离子催化在插烯Michael加成反应与对β位有较大位阻的芳基的醛的动力学拆分中的应用... 
Dissertation
西华师范大学学报:自然科学版, ISSN 1673-5072, 2012, Volume 33, Issue 1, pp. 40 - 44
O625.63; 金鸡纳碱衍生的季铵盐催化二苯亚甲基甘氨酸叔丁酯与α,β不饱和酮的不对称Michael加成反应,常温条件下取得99%的产率,达到57%的对映选择性以及高于20∶1的区域选择性.合成了7个未见文献报道的取代的甘氨酸衍生物,其结构得到1H NMR确证. 
Journal Article
2009, Blackwell handbooks in linguistics, ISBN 9781405154895, Volume 67, xix, 803
Bringing together an international and interdisciplinary team of contributors, this Handbook is a wide-ranging and invaluable reference guide to language... 
Language and languages | Second language acquisition | Handbooks, manuals, etc | Study and teaching
Book
济南大学学报(自然科学版), ISSN 1671-3559, 2016, Volume 30, Issue 3, pp. 184 - 189
O625.2;... 
Journal Article
应用化工, ISSN 1671-3206, 2013, Volume 42, Issue 6, pp. 1081 - 1088
TQ463.5; 以甘氨酸和丙烯腈为原料,经过迈克尔加成反应、酯化反应、氨基保护以及Dieckmann环合等4步反应,制备了1-Boc-3-氰基-4-吡咯烷酮,总收率66.4%.对关键的Michael加成和Dieckmann环合反应条件进行了优化,得到较佳反应条件:①迈克尔加成反应:丙烯腈与甘氨酸的摩尔比为1.1∶1... 
Journal Article
by Kanchi, Rupa S and Hegde, Apurva M and Lenoir, Walter and Liu, Wenbin and Liu, Yuexin and Shen, Hui and Rao, Arvind and Schultz, Andre and Li, Xubin and Sumazin, Pavel and Mestdagh, Pieter and Gunaratne, Preethi H and Yau, Christina and Bowlby, Reanne and Robertson, A. Gordon and Tiezzi, Daniel G and Godwin, Andrew K and Sood, Anil K and Adebamowo, Clement and Baggerly, Keith A and Chiu, Hua-Sheng and Liu, Liang and MacKenzie, Karen and Orsulic, Sandra and Roszik, Jason and Shelley, Carl Simon and Song, Qianqian and Vellano, Christopher P and Wentzensen, Nicolas and Weinstein, John N and Mills, Gordon B and Levine, Douglas A and Caesar-Johnson, Samantha J and Kasapi, Melpomeni and Ferguson, Martin L and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Zenklusen, Jean C and Chudamani, Sudha and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Miller, Michael and Reynolds, Sheila and Thorsson, Vesteinn and Broom, Bradley M and Ju, Zhenlin and Li, Jun and Ling, Shiyun and Lu, Yiling and Ryan, Michael and Zhang, Jiexin and Abeshouse, Adam and Armenia, Joshua and Chatila, Walid K and Gross, Benjamin E and Kundra, Ritika and La, Konnor and Luna, Augustin and Ochoa, Angelica and Phillips, Sarah M and Reznik, Ed and Sanchez-Vega, Francisco and Sander, Chris and Schultz, Nikolaus and Sheridan, Robert and Sumer, S. Onur and Taylor, Barry S and Wang, Jioajiao and Wong, Christopher K and Hayes, D. Neil and Parker, Joel S and Wilkerson, Matthew D and Ally, Adrian and Balasundaram, Miruna and Brooks, Denise and Chuah, Eric and Dhalla, Noreen and Lee, Darlene and Marra, Marco A and ... and The Cancer Genome Atlas Research Network and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Cancer cell, ISSN 1535-6108, 04/2018, Volume 33, Issue 4, pp. 690 - 705.e9
We analyzed molecular data on 2,579 tumors from The Cancer Genome Atlas (TCGA) of four gynecological types plus breast. Our aims were to identify shared and... 
omics | ovarian cancer | uterine cancer | gynecologic cancer | breast cancer | uterine carcinosarcoma | pan-gynecologic | cervical cancer | TCGA | The Cancer Genome Atlas | Oncology | Cell Biology | Cancer Research | Life Sciences & Biomedicine | Science & Technology | Index Medicus | molecular features | Pan-Gynecologic | Gynecologic cancer
Journal Article