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1. Full Text Response to LTE 19-01163
by Goldberg, Rimma and Lord, Graham M
Gastroenterology, ISSN 0016-5085, 10/2019
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2. Full Text Immunomodulatory role of Keratin 76 in oral and gastric cancer
by Sequeira, Inês and Neves, Joana F and Carrero, Dido and Peng, Qi and Palasz, Natalia and Liakath-Ali, Kifayathullah and Lord, Graham M and Morgan, Peter R and Lombardi, Giovanna and Watt, Fiona M
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3437 - 15
Keratin 76 (Krt76) is expressed in the differentiated epithelial layers of skin, oral cavity and squamous stomach. Krt76 downregulation in human oral squamous... 
HEAD | CARCINOGENESIS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | REGULATORY T-CELLS | GENOME-WIDE | SKIN | EXPRESSION | NECK-CANCER | TUMOR MICROENVIRONMENT | T-Lymphocytes, Regulatory - metabolism | Keratins - immunology | Humans | Mice, Inbred C57BL | Apyrase - metabolism | In Situ Hybridization, Fluorescence | Male | Antigens, CD - metabolism | Mice, Knockout | Mouth Neoplasms - immunology | Stomach Neoplasms - immunology | Animals | Flow Cytometry | Mice, Mutant Strains | Fluorescent Antibody Technique | Cell Line, Tumor | Female | Mice | 5'-Nucleotidase - metabolism | In Vitro Techniques | Epithelial cells | Effector cells | Lymphocytes T | Carcinogenesis | Lymph nodes | Keratin | Carcinogens | Lymphocytes | Bioaccumulation | CD73 antigen | Gastric cancer | Immune system | Enlargement | Spleen | Oral carcinoma | Stomach | Cytokines | Immunoregulation | Immunomodulation | Inflammation | Oral squamous cell carcinoma | Ablation | Communications systems | Oral cavity | Skin | Tumors | Index Medicus
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3. Full Text Boosting translational research in the U.K
by Anandagoda, Nelomi and Lord, Graham M
Science Translational Medicine, ISSN 1946-6234, 09/2016, Volume 8, Issue 357, pp. 357fs15 - 357fs15
Investment in national infrastructure is critical for growth in early-phase translational research and experimental medicine. 
MEDICINE, RESEARCH & EXPERIMENTAL | STRATEGY | CELL BIOLOGY | Industry | Delivery of Health Care | Humans | Translational Medical Research | Cooperative Behavior | United Kingdom | Universities
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4. Full Text Allogeneic immunotherapy for malignant diseases
by Barrett, John, 1945 July 20 and Jiang, Yin-Zheng, 1963 and MyiLibrary
2000, Basic and clinical oncology, ISBN 0824767810, Volume 22, 392
This important reference offers a comprehensive review of the graft-versus-leukemia (GVL) or -tumor (GVT) effect following allogeneic stem cell transplantation... 
Hematologic Neoplasms | Leukemia | Immunotherapy | therapy | Bone marrow | Hematopoietic Stem Cell Transplantation | Graft versus host reaction | Graft vs Tumor Effect | Transplantation | Hematopoietic stem cells | Transplantation, Homologous | Cancer | Hematological oncology
eBook
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5. Full Text T-bet: A bridge between innate and adaptive immunity
by Lazarevic, Vanja and Glimcher, Laurie H and Lord, Graham M
Nature Reviews Immunology, ISSN 1474-1733, 11/2013, Volume 13, Issue 11, pp. 777 - 789
Originally described over a decade ago as a T cell transcription factor regulating T helper 1 cell lineage commitment, T-bet is now recognized as having an... 
IFN-GAMMA PRODUCTION | INTERFERON-GAMMA | DENDRITIC CELLS | TRANSCRIPTION FACTOR EOMESODERMIN | V-ALPHA-14I NKT CELLS | PATHOGENIC T(H)17 CELLS | GENE-EXPRESSION | TH1 CELL-DIFFERENTIATION | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | LYMPHOID-CELLS | Adaptive Immunity | T-Box Domain Proteins - physiology | T-Lymphocyte Subsets - immunology | Animals | B-Lymphocytes - immunology | T-Lymphocyte Subsets - cytology | T-Lymphocyte Subsets - metabolism | Humans | Immunologic Memory | Immunity, Innate | Natural immunity | Genetic aspects | Research | T cells | Health aspects | Cell lineage
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6. Aristolochic acid nephropathy
by M Refik Gökmen and Graham M Lord
British Medical Journal, ISSN 0959-8146, 07/2012, Volume 345, Issue 7865, p. 9
Gokmen and Lord discuss the potential risks associated with the unregulated use of herbal medicines. More than 20 years ago a Belgian report described nine... 
Herbal medicine | Nephrology | Kidney diseases | Patients | Risk factors
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7. Identification evidence
: a psychological evaluation
by Shepherd, John W and Ellis, Hadyn and Davies, Graham (Graham M.)
1982, ISBN 9780080284415, xii, 155
Identification | Identification (Psychology)
Book
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8. Full Text The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor+ Innate Lymphoid Cells
by Powell, Nick and Walker, Alan W and Stolarczyk, Emilie and Canavan, James B and Gökmen, M. Refik and Marks, Ellen and Jackson, Ian and Hashim, Ahmed and Curtis, Michael A and Jenner, Richard G and Howard, Jane K and Parkhill, Julian and MacDonald, Thomas T and Lord, Graham M
Immunity, ISSN 1074-7613, 10/2012, Volume 37, Issue 4, pp. 674 - 684
Mice lacking the transcription factor T-bet in the innate immune system develop microbiota-dependent colitis. Here, we show that interleukin-17A... 
COLITIS | DATABASE | TYPHLITIS | LOCI | MUCOSAL | IMMUNOLOGY | DEFICIENCY | ADULT | IL-7 | DNA-Binding Proteins - immunology | Signal Transduction | T-Box Domain Proteins - deficiency | Cells, Cultured | Helicobacter - immunology | Colitis, Ulcerative - pathology | T-Box Domain Proteins - immunology | Immunity, Innate | Colitis, Ulcerative - immunology | DNA-Binding Proteins - deficiency | Mice, Knockout | Animals | Lymphocytes - immunology | Colitis, Ulcerative - microbiology | Mice | Mice, Inbred BALB C | Chronic Disease | Receptors, Interleukin-7 - immunology | Inflammatory bowel disease | Medical research | Cytokines | Rodents | Immune system
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9. Full Text Immune biomarkers: The promises and pitfalls of personalized medicine
by Willis, Joanna C.D and Lord, Graham M
Nature Reviews Immunology, ISSN 1474-1733, 04/2015, Volume 15, Issue 5, pp. 323 - 329
Substantial progress in molecular immunology, coupled with an increasing focus on translational research and an enthusiasm for personalized medicine, has... 
SURROGATE END-POINTS | THERAPY | TOLERANCE | DISEASE | REGULATORY T-CELLS | ANTIBODY | MICRORNAS | IMMUNOLOGY | STEM-CELL TRANSPLANTATION | CANCER | SIGNATURE | Biological markers | Analysis
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10. How might a diagnostic microRNA signature be used to speed up the diagnosis of sepsis?
by Shankar-Hari, Manu and Lord, Graham M
Expert Review of Molecular Diagnostics, ISSN 1473-7159, 04/2014, Volume 14, Issue 3, pp. 249 - 251
Sepsis is a heterogeneous illness characterised by inflammation secondary to suspected or proven infection. A clinical and research challenge in this area is... 
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11. Full Text T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements
by Kanhere, Aditi and Hertweck, Arnulf and Bhatia, Urvashi and Gökmen, M. Refik and Perucha, Esperanza and Jackson, Ian and Lord, Graham M and Jenner, Richard G
Nature Communications, ISSN 2041-1723, 2012, Volume 3, Issue 1, p. 1268
T-bet and GATA3 regulate the CD4+ T cell Th1/Th2 cell fate decision but little is known about the interplay between these factors outside of the murine Ifng... 
HELPER TYPE-1 CELLS | COMMITMENT | CHROMATIN | MULTIDISCIPLINARY SCIENCES | ENCODING INTERFERON-GAMMA | TRANSCRIPTION FACTOR GATA-3 | CYTOKINE GENE-EXPRESSION | LOCUS | COORDINATED EXPRESSION | GENOME | IL4 SILENCER | T-Box Domain Proteins - physiology | Th1 Cells - physiology | Th2 Cells - physiology | Oligonucleotide Array Sequence Analysis | Humans | Regulatory Sequences, Nucleic Acid | GATA3 Transcription Factor - physiology | CD4-Positive T-Lymphocytes - physiology | Animals | Binding Sites - physiology | Mice | Mice, Inbred BALB C | Cell Differentiation - physiology | Gene Expression Regulation, Developmental - physiology
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12. Full Text Communicable Ulcerative Colitis Induced by T-bet Deficiency in the Innate Immune System
by Garrett, Wendy S and Lord, Graham M and Punit, Shivesh and Lugo-Villarino, Geanncarlo and Mazmanian, Sarkis K and Ito, Susumu and Glickman, Jonathan N and Glimcher, Laurie H
Cell, ISSN 0092-8674, 2007, Volume 131, Issue 1, pp. 33 - 45
Inflammatory bowel disease (IBD) has been attributed to overexuberant host immunity or the emergence of harmful intestinal flora. The transcription factor... 
HUMDISEASE | MICROBIO | CELLIMMUNO | ACTIVATION | HOMEOSTASIS | INFLAMMATORY-BOWEL-DISEASE | COLONY-STIMULATING FACTOR | DENDRITIC CELLS | CROHNS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GUT | MUTUALISM | HUMAN INTESTINE | CULTURES | CELL BIOLOGY | Colon - cytology | Dendritic Cells - immunology | Humans | Colitis, Ulcerative - immunology | CD4-Positive T-Lymphocytes - immunology | DNA-Binding Proteins - metabolism | Intestinal Mucosa - immunology | Tumor Necrosis Factor-alpha - immunology | Female | Interleukin-2 Receptor alpha Subunit - immunology | Colon - pathology | Gene Expression Regulation | Colitis, Ulcerative - pathology | Intestinal Mucosa - microbiology | DNA-Binding Proteins - genetics | Immunity, Innate | T-Box Domain Proteins - genetics | Colon - metabolism | T-Box Domain Proteins - metabolism | Mice, Knockout | Animals | Colitis, Ulcerative - microbiology | Dendritic Cells - cytology | Mice | Colitis, Ulcerative - physiopathology | Intestinal Mucosa - pathology | Immune system | Ulcerative colitis | Life Sciences | Immunology
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13. Full Text Retinoic Acid Is Essential for Th1 Cell Lineage Stability and Prevents Transition to a Th17 Cell Program
by Brown, Chrysothemis C and Esterhazy, Daria and Sarde, Aurelien and London, Mariya and Pullabhatla, Venu and Osma-Garcia, Ines and al-Bader, Raya and Ortiz, Carla and Elgueta, Raul and Arno, Matthew and de Rinaldis, Emanuele and Mucida, Daniel and Lord, Graham M and Noelle, Randolph J
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 499 - 511
CD4 T cells differentiate into phenotypically distinct T helper cells upon antigenic stimulation. Regulation of plasticity between these CD4 T-cell lineages is... 
IMMUNITY | TRANSCRIPTIONAL ACTIVATION | TGF-BETA | INTERFERON-GAMMA | CHROMATIN | EMBRYONIC STEM-CELLS | T(H)17 | DIFFERENTIATION | IMMUNOLOGY | T-CELLS | PLASTICITY | Gene Regulatory Networks | Th1 Cells - immunology | Cell Lineage - drug effects | Receptors, Retinoic Acid - genetics | T-Lymphocytes, Helper-Inducer - drug effects | Th17 Cells - drug effects | T-Lymphocytes, Helper-Inducer - immunology | Receptors, Retinoic Acid - immunology | T-Lymphocytes, Helper-Inducer - cytology | Integrases - metabolism | Th17 Cells - cytology | Homeostasis - drug effects | Tretinoin - pharmacology | Th1 Cells - drug effects | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Homeostasis - immunology | Tretinoin - immunology | Mice, Knockout | Cell Differentiation - immunology | Animals | Cell Differentiation - drug effects | Th17 Cells - immunology | Mice | Th1 Cells - cytology | Integrases - genetics | Retinoic Acid Receptor alpha | Cell Lineage - immunology | T cells | Tretinoin | Studies | Medical research | Antigens | Biomedical research | Lymphocytes | Rodents | Stem cells | Epigenetics | T cell receptors | Gene expression
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14. Full Text Longitudinal Magnetic Resonance Imaging Study of Cortical Development through Early Childhood in Autism
by Schumann, Cynthia M and Bloss, Cinnamon S and Barnes, Cynthia Carter and Wideman, Graham M and Carper, Ruth A and Akshoomoff, Natacha and Pierce, Karen and Hagler, Donald and Schork, Nicholas and Lord, Catherine and Courchesne, Eric
Journal of Neuroscience, ISSN 0270-6474, 03/2010, Volume 30, Issue 12, pp. 4419 - 4427
Cross-sectional magnetic resonance imaging (MRI) studies have long hypothesized that the brain in children with autism undergoes an abnormal growth trajectory... 
SURFACE-BASED ANALYSIS | 2ND YEAR | MRI | HEAD CIRCUMFERENCE GROWTH | SPECTRUM DISORDERS | 1ST YEAR | NEUROANATOMY | BRAIN SIZE | NEUROSCIENCES | LIFE | CHILDREN | Severity of Illness Index | Autistic Disorder - pathology | Humans | Cerebral Cortex - pathology | Child, Preschool | Magnetic Resonance Imaging - methods | Infant | Male | Reference Values | Image Processing, Computer-Assisted | Sex Factors | Brain Mapping | Cerebral Cortex - growth & development | Female | Child Development | Longitudinal Studies
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