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ISSN 1534-4827, 2018
Abstract Purpose of the review: Causality has been demonstrated for few of the many putative risk factors for type 2 diabetes (T2D) emerging from observational... 
Journal Article
Haematologica, ISSN 0390-6078, 02/2019, p. haematol.2018.204990
Primary platelet secretion defects are heterogeneous group of functional defects characterized by reduced platelet granule secretion upon stimulation by... 
Journal Article
ISSN 2213-8587, 2017
The focus of cardiovascular disease prevention has shifted from normalisation of risk factors to absolute risk reduction. Reducing low-density lipoprotein... 
Humans | Cholesterol, LDL | Diabetes Mellitus, Type 2 | Proprotein Convertase 9
Journal Article
Journal Article
JAMA, ISSN 0098-7484, 10/2016, Volume 316, Issue 13, pp. 1383 - 1391
Journal Article
by Lotta, Luca A and Gulati, Pawan and Day, Felix R and Payne, Felicity and Ongen, Halit and van de Bunt, Martijn and Gaulton, Kyle J and Eicher, John D and Sharp, Stephen J and Luan, Jian'an and de Lucia Rolfe, Emanuella and Stewart, Isobel D and Wheeler, Eleanor and Willems, Sara M and Adams, Claire and Yaghootkar, Hanieh and Forouhi, Nita G and Khaw, Kay-Tee and Johnson, Anew D and Semple, Robert K and Frayling, Timothy and Perry, John R. B and Dermitzakis, Emmanouil and McCarthy, Mark I and Barroso, Inês and Wareham, Nicholas J and Savage, David B and Langenberg, Claudia and O'Rahilly, Stephen and Scott, Robert A and Kerrison, Nicola D and Sims, Matt and Lucarelli, Debora M. E and Deloukas, Panos and Arriola, Larraitz and Balkau, Beverley and Barricarte, Aurelio and Boeing, Heiner and Franks, Paul W and Gonzalez, Carlos and Grioni, Sara and Kaaks, Rudolf and Key, Timothy J and Navarro, Carmen and Nilsson, Peter M and Overvad, Kim and Palli, Domenico and Panico, Salvatore and Quirós, J. Ramón and Rolandsson, Olov and Sacerdote, Carlotta and Salamanca-Fernández, Elena and Slimani, Nadia and Tjonneland, Anne and Tumino, Rosario and Spijkerman, Annemieke M. W and van der A, Daphne L and van der Schouw, Yvonne T and Riboli, Elio and Stears, Anna and George, Stella and Walker, Mark and Gurnell, Ellie and Maguire, Deire and Mukhtar, Rasha and Nag, Sath and Adler, Amanda and Soeters, Maarten R and Laji, Ken and Watt, Alistair and Aylwin, Simon and Johnson, Anew and Rayman, Gerry and Hanna, Fahmy and Ellard, Sian and Ross, Richard and Blaslov, Kristina and Duvnjak, Lea Smirčić and Cambridge FPLD1 Consortium and EPIC-InterAct Consortium and Lund University and EpiHealth: Epidemiology for Health and Institutionen för kliniska vetenskaper, Malmö and Genetic and Molecular Epidemiology and Genetisk och molekylär epidemiologi and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden and Department of Clinical Sciences, Malmö
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 1, pp. 17 - 26
Journal Article
by Gusarova, Viktoria and O'Dushlaine, Colm and Teslovich, Tanya M and Benotti, Peter N and Mirshahi, Tooraj and Gottesman, Omri and Van Hout, Cristopher V and Murray, Michael F and Mahajan, Anubha and Nielsen, Jonas B and Fritsche, Lars and Wulff, Anders Berg and Gudbjartsson, Daniel F and Sjögren, Marketa and Emdin, Connor A and Scott, Robert A and Lee, Wen-Jane and Small, Aeron and Kwee, Lydia C and Dwivedi, Om Prakash and Prasad, Rashmi B and Bruse, Shannon and Lopez, Alexander E and Penn, John and Marcketta, Anthony and Leader, Joseph B and Still, Christopher D and Kirchner, H. Lester and Mirshahi, Uyenlinh L and Wardeh, Amr H and Hartle, Cassandra M and Habegger, Lukas and Fetterolf, Samantha N and Tusie-Luna, Teresa and Morris, Andrew P and Holm, Hilma and Steinthorsdottir, Valgerdur and Sulem, Patrick and Thorsteinsdottir, Unnur and Rotter, Jerome I and Chuang, Lee-Ming and Damrauer, Scott and Birtwell, David and Brummett, Chad M and Khera, Amit V and Natarajan, Pradeep and Orho-Melander, Marju and Flannick, Jason and Lotta, Luca A and Willer, Cristen J and Holmen, Oddgeir L and Ritchie, Marylyn D and Ledbetter, David H and Murphy, Andrew J and Borecki, Ingrid B and Reid, Jeffrey G and Overton, John D and Hansson, Ola and Groop, Leif and Shah, Svati H and Kraus, William E and Rader, Daniel J and Chen, Yii-Der I and Hveem, Kristian and Wareham, Nicholas J and Kathiresan, Sekar and Melander, Olle and Stefansson, Kari and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and Abecasis, Goncalo R and Altshuler, David and Florez, Jose C and Boehnke, Michael and McCarthy, Mark I and Yancopoulos, George D and Carey, David J and Shuldiner, Alan R and Baras, Aris and Dewey, Frederick E and Gromada, Jesper and Diabetes - Cardiovascular Disease and Kardiovaskulär forskning - hypertoni and Cardiovascular Research - Hypertension and Diabetes - kardiovaskulär sjukdom and Lund University and Genomics, Diabetes and Endocrinology and EpiHealth: Epidemiology for Health and Genomik, diabetes och endokrinologi and Institutionen för kliniska vetenskaper, Malmö and Lunds universitet and Department of Clinical Sciences, Malmö
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2252 - 11
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient... 
HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | MULTIDISCIPLINARY SCIENCES | MICE | ANGIOPOIETIN-LIKE PROTEIN-4 | LIPOPROTEIN-LIPASE | HAN CHINESE | CHINESE POPULATION | GENOME-WIDE ASSOCIATION | ADIPOSE-TISSUE | Diabetes Mellitus, Type 2 - genetics | Humans | Homeostasis | Male | Diabetes Mellitus, Type 2 - metabolism | Case-Control Studies | Genetic Variation | Diabetes Mellitus, Type 2 - etiology | Female | Lipoprotein Lipase - metabolism | Genetic Association Studies | Mice, Inbred C57BL | Risk Factors | Gene Silencing | Angiopoietin-like 4 Protein - deficiency | Mice, Knockout | Whole Exome Sequencing | Animals | Insulin Resistance - genetics | Angiopoietin-like 4 Protein - metabolism | Heterozygote | Mice | Blood Glucose - metabolism | Amino Acid Substitution | Angiopoietin-like 4 Protein - genetics | Deactivation | Angiopoietin | Diabetes mellitus | Health risks | Risk reduction | Risk | Lipoprotein lipase | Glucose | Lipase | Inactivation | Insulin | Proteins | Confidence intervals | Sensitivity | Nutrient loss | Rodents | Arteriosclerosis | Atherosclerosis | Genetics | Diabetes | Diabetes mellitus (non-insulin dependent) | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Klinisk medicin | Endocrinology and Diabetes
Journal Article
The Lancet Diabetes & Endocrinology, ISSN 2213-8587, 12/2017, Volume 5, Issue 12, pp. 926 - 927
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 09/2015, Volume 107, Issue 9, p. 1
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 2014, Volume 63, Issue 12, pp. 4378 - 4387
We aimed to validate genetic variants as instruments for insulin resistance and secretion, to characterize their association with intermediate phenotypes, and... 
FASTING GLUCOSE | ENDOCRINOLOGY & METABOLISM | GLYCEMIC TRAITS | SENSITIVITY | RISK | LOCI | MECHANISMS | PROINSULIN | ASSOCIATION | RECEPTOR SUBSTRATE-1 | PATHOPHYSIOLOGY | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | Genetic Variation | Overweight - metabolism | Body Composition - genetics | Adult | Female | Body Fat Distribution | Insulin Secretion | Waist Circumference - genetics | Body Mass Index | Genetic Predisposition to Disease | Glucose Tolerance Test | gamma-Glutamyltransferase - metabolism | Obesity - metabolism | Insulin - metabolism | Insulin Resistance - genetics | Aged | Polymorphism, Single Nucleotide | Alanine Transaminase - metabolism | Glucose Clamp Technique | Cohort Studies | Type 2 diabetes | Genetic variation | Analysis | Insulin resistance | Genetic aspects | Research | Risk factors | Genotype & phenotype | Obesity | Body mass index | Glucose | Weight | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | 2007 | V87 | 2003 | V46 | JOURNAL OF CLINICAL INVESTIGATION | 1979 | PE214 thelius B | P220 ms EAH | AMERICAN JOURNAL OF PHYSIOLOGY | V117 | V237 | 2001 | INTERNATIONAL JOURNAL OF EPIDEMIOLOGY | P507 iderman Allan D | P1499 | V50 | P2155 vage David B | DIABETOLOGIA | V36 | METABOLISM-CLINICAL AND EXPERIMENTAL | FRONZO RA | P20 ssenko Valeriya | PHYSIOLOGICAL REVIEWS
Journal Article
Journal Article