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Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 06/2010, Volume 339, Issue 1-2, p. 253
We have previously reported that the increase in c-Jun expression induced by quercetin inhibited androgen receptor (AR) transactivation, and Sp1 was involved... 
Infection | Luciferase | Cancer cells | Kallikrein | Prostate cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2014, Volume 9, Issue 4, p. e93567
GPBAR1/TGR5 is a novel plasma membrane-bound G protein-coupled bile acid (BA) receptor. BAs are known to induce the expression of inflammatory cytokines in the... 
HYDROXYLASE | TARGETED DISRUPTION | ACTIVATION | RECEPTOR TGR5 | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | NECROSIS-FACTOR-ALPHA | MICE | CHOLESTEROL 7-ALPHA-HYDROXYLASE | NF-KAPPA-B | EPAC | Bile Acids and Salts - pharmacology | Liver - enzymology | Receptors, G-Protein-Coupled - metabolism | Humans | Tumor Necrosis Factor-alpha - genetics | Oleanolic Acid - pharmacology | JNK Mitogen-Activated Protein Kinases - metabolism | Promoter Regions, Genetic - genetics | HEK293 Cells | Inflammation Mediators - metabolism | Kupffer Cells - metabolism | Phosphorylation - drug effects | Cytokines - genetics | Hepatocytes - drug effects | Cell Line | Cytokines - metabolism | Mice, Inbred C57BL | Activating Transcription Factor 2 - metabolism | Kupffer Cells - drug effects | Gene Expression Regulation - drug effects | Cholesterol 7-alpha-Hydroxylase - genetics | Animals | Cholesterol 7-alpha-Hydroxylase - metabolism | Proto-Oncogene Proteins c-jun - metabolism | Culture Media - pharmacology | Liver - cytology | Hepatocytes - enzymology | Cytokines | Tumor necrosis factor | Analysis | G proteins | Chemical properties | Protein binding | Deoxycholic acid | Phosphorylation | Transcription factors | Liver | Hydroxylase | Interleukin | Kupffer cells | c-Jun protein | Activation | Inflammation | Tumor necrosis factor-α | Cholic acid | IL-1β | Kinases | Macrophages | Cholesterol | Membrane proteins | Acids | Hepatocytes | External stimuli | Rodents | Tumor necrosis factor-TNF | Deoxyribonucleic acid--DNA | Bile | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
World Allergy Organization Journal, ISSN 1939-4551, 2016, Volume 9, p. 14
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2012, Volume 44, Issue 2, pp. 178 - 182
We performed a two-stage genome-wide association study of IgA nephropathy (IgAN) in Han Chinese, with 1,434 affected individuals (cases) and 4,270 controls in... 
GLOMERULONEPHRITIS | URINARY LEVELS | ALLELES | B-CELL | GENETICS & HEREDITY | HAPLOTYPES | IMMUNOGLOBULIN-A NEPHROPATHY | HLA | PROGRESSION | GENETIC-FACTORS | APRIL | IgA glomerulonephritis | Major histocompatibility complex | Demographic aspects | Analysis | Genetic aspects | Research | Risk factors | Studies | Haplotypes | Genes | Genetics | Principal components analysis | Genomes | Methods | Independent sample
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 12/2018, Volume 22, Issue 12, pp. 6314 - 6326
Aim Diabetic cardiomyopathy is an independent cardiac injury that can develop in diabetic individuals. Our previous study showed that C66, a curcumin analogue,... 
apoptosis | JNK2 | C66 | diabetic cardiomyopathy | oxidative stress | curcumin | TRANSCRIPTION FACTORS | MEDICINE, RESEARCH & EXPERIMENTAL | PATHWAY | JUN NH2-TERMINAL KINASE | FOXO3A | CELL BIOLOGY | Heart | Glucose | RNA | Analysis | Body weight | Dextrose | Oxidative stress | Deactivation | Cardiomyopathy | Analogue | Diabetes mellitus | mRNA | Inactivation | Proteins | Rodents | Fibrosis | Mice | Curcumin | Diabetes | Apoptosis | Structure-function relationships | Original
Journal Article
CARCINOGENESIS, ISSN 0143-3334, 10/1994, Volume 15, Issue 10, pp. 2363 - 2370
Expression of c-jun protein (c-Jun) was observed in normally proliferating JB6 cells but not in confluent cells. Reduction of the serum concentration from 5%... 
ESTER TUMOR PROMOTERS | PROTEIN-KINASE-C | NIH 3T3 CELLS | ONCOGENE | ACTIVATION | ONCOLOGY | FIBROBLAST CELLS | INDUCTION | PHORBOL ESTER | SIGNAL TRANSDUCTION PATHWAYS | DNA-BINDING ACTIVITY
Journal Article
Biochimica et Biophysica Acta - Bioenergetics, ISSN 0005-2728, 10/2010, Volume 1797, Issue 10, pp. 1705 - 1715
Glutaredoxin 2 (Grx2) belongs to the oxidoreductase family and is an isozyme of glutaredoxin 1 (Grx1) present in the mitochondria, however its function is not... 
Mitochondria | Hydrogen peroxide | Glutaredoxin2 | Reactive oxygen species (ROS) | Complex I | Free radical | Apoptosis | JUN | THIOLTRANSFERASE | GRX2 | LENS EPITHELIAL-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOXORUBICIN | BIOPHYSICS | REDOX REGULATION | THIOREDOXIN REDUCTASE | PROTEINS | EXPRESSION
Journal Article
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 04/2017, Volume 201, pp. 108 - 116
The Qingchangligan formula, a traditional Chinese medicine comprising five herbs, is useful for treatment of patients with liver failure; however, its... 
ERKextracellular regulated protein kinase | H&Ehematoxylin and eosin | ALFacute liver failure | IL-12p40interleukin-12p40 | PAGEpolyacrylamide gel electrophoresis | Autophagy | D-GalND-galactosamine | BMDMsmurine bone marrow-derived macrophages | DAPI49,6-diamino-2-phenylindole | MAPKmitogen-activated protein kinase | Atgautophagy-related gene | NF-kBtranscription factor nuclear factor-kB | PBSphosphate-buffered saline | Acute liver failure | LPSlipopolysaccharide | CXCL-10chemokine (C-X-C motif) ligand-10 | ASTaspartate aminotransferase | IL-1βinterleukin-1β | TUNELtransferase-mediated dUTP nick-end labeling | ERendoplasmic reticulum | Inflammation | JNKc-jun-N-terminal kinase | TNF-αtumor necrosis factor-α | ALTalanine aminotransferase | PVDFpolyvinylidene difluoride | TBSTTris-buffered saline with Tween-20 | Qingchangligan formula | qRT-PCRquantitative reverse transcription-polymerase chain reaction | Apoptosis | CHEMISTRY, MEDICINAL | INJURY | ALPHA | MECHANISMS | MODEL | AUTOPHAGY PROTECTS | CELL-DEATH | PLANT SCIENCES | PATHOGENESIS | INTEGRATIVE & COMPLEMENTARY MEDICINE | PHARMACOLOGY & PHARMACY | FULMINANT HEPATIC-FAILURE | GALACTOSAMINE-SENSITIZED MICE | Galactosamine | Microtubule-Associated Proteins - genetics | Anti-Inflammatory Agents - pharmacology | Apoptosis - drug effects | Liver - metabolism | Mice, Inbred C57BL | Drugs, Chinese Herbal - pharmacology | Liver Failure, Acute - chemically induced | Male | Alanine Transaminase - blood | Lipopolysaccharides | Animals | Aspartate Aminotransferases - blood | Liver - drug effects | Anti-Inflammatory Agents - therapeutic use | Liver Failure, Acute - drug therapy | Phytotherapy | Drugs, Chinese Herbal - therapeutic use | Hepatocytes - drug effects | Cytokines - blood | Mitogen-Activated Protein Kinases - metabolism | Medicine, Herbal | Liver diseases | Liver | Medicine, Botanic | Analysis
Journal Article
Molecular Medicine Reports, ISSN 1791-2997, 03/2018, Volume 17, Issue 3, pp. 4573 - 4580
Propofol postconditioning (P-PostC) offers cardioprotection in mice, and the upregulation of autophagy protects cardiac cells against ischemia/reperfusion... 
Myocardial ischemia | Cardioprotection | Ischemic postconditioning | Autophagy | MEDICINE, RESEARCH & EXPERIMENTAL | ischemic postconditioning | autophagy | INDUCED APOPTOSIS | JNK | MYOCARDIAL-ISCHEMIA | REPERFUSION | DEATH | INHIBITION | ONCOLOGY | cardioprotection | myocardial ischemia | DIFFERENTIATION | LC3 | MOLECULAR-MECHANISMS
Journal Article