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Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1408 - 1413
Neuroblastoma is a tumor of the peripheral sympathetic nervous system(1), derived from multipotent neural crest cells (NCCs). To define core regulatory... 
HUMAN GENOME | SUPER-ENHANCERS | GENE | GENETICS & HEREDITY | N-MYC | NEURONAL DIFFERENTIATION | ALK KINASE | REARRANGEMENTS | ACTIVATING MUTATIONS | PHOX2B | NEURAL CREST CELLS | Homeodomain Proteins - metabolism | Humans | Cell Lineage - drug effects | Cell Line, Tumor - classification | RNA Interference | HEK293 Cells | Gene Expression Regulation, Neoplastic - drug effects | Single-Cell Analysis | Cell Lineage - genetics | Gene Expression Regulation, Neoplastic - genetics | Neuroblastoma - genetics | Gene Expression Profiling - methods | Transcription Factors - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Xenograft Model Antitumor Assays - methods | Blotting, Western | Genetic Heterogeneity | Homeodomain Proteins - genetics | Mice, Knockout | Transcription Factors - metabolism | Animals | Neuroblastoma - drug therapy | Doxycycline - pharmacology | Mice, Inbred NOD | Neuroblastoma - metabolism | RNAi Therapeutics | Cancer cells | Physiological aspects | Development and progression | Genetic aspects | Neuroblastoma | Research | Genetic transcription | Transcription factors | Modules | Activator protein 1 | Principal components analysis | Genomes | Gene expression | Neural crest | Heterogeneity | Chemotherapy | Addiction | Cell lines | Cell cycle | GATA-3 protein | Norepinephrine | Mutation | Bioinformatics | Phox2b protein | Deoxyribonucleic acid--DNA | Cancer | Tumors | Index Medicus | Life Sciences | Neurons and Cognition | Biochemistry, Molecular Biology | Genomics | Neurobiology
Journal Article
Journal Article
International journal of cancer, ISSN 0020-7136, 04/2019
In neuroblastoma (NB), genetic alterations in chromatin remodeling (CRGs) and epigenetic modifier genes (EMGs) have been described. We sought to determine... 
Journal Article
Cancer Research, ISSN 0008-5472, 10/2018, Volume 78, Issue 19 Supplement, pp. B20 - B20
Journal Article
Modern Pathology, ISSN 0893-3952, 05/2011, Volume 24, Issue 5, pp. 624 - 637
Low-grade osteosarcoma is a rare malignancy that may be subdivided into two main subgroups on the basis of location in relation to the bone cortex, that is,... 
MDM2 | immunohistochemistry | CDK4 | parosteal osteosarcoma | low-grade osteosarcoma | H-RAS GENES | INTRAOSSEOUS OSTEOSARCOMA | 12Q13-15 GENES | PATHOLOGY | FIBROUS DYSPLASIA | RESEMBLING PAROSTEAL OSTEOSARCOMA | MOLECULAR ANALYSIS | OSTEOGENIC-SARCOMA | CYTOGENETIC FINDINGS | COMPARATIVE GENOMIC HYBRIDIZATION | OF-THE-LITERATURE | Proto-Oncogene Proteins c-mdm2 - genetics | Cyclin-Dependent Kinase 4 - genetics | Humans | Middle Aged | Male | Osteosarcoma - diagnosis | Bone Neoplasms - metabolism | Young Adult | Biomarkers, Tumor - metabolism | Adult | Female | Bone Neoplasms - genetics | DNA, Neoplasm - analysis | Child | Proto-Oncogene Proteins c-mdm2 - metabolism | Osteosarcoma - metabolism | Fibrous Dysplasia of Bone - genetics | Gene Expression | Bone Neoplasms - diagnosis | In Situ Hybridization, Fluorescence | Comparative Genomic Hybridization - methods | Cyclin-Dependent Kinase 4 - metabolism | Fibrous Dysplasia of Bone - diagnosis | Fibrous Dysplasia of Bone - metabolism | Gene Amplification | Immunoenzyme Techniques - methods | Adolescent | Aged | Biomarkers, Tumor - genetics | Osteosarcoma - genetics | MDM2 protein | Sarcoma | Benign | Stroma | Bone tumors | Cyclin-dependent kinase 4 | Polymerase chain reaction | Biopsy | Osteosarcoma | Fibrous dysplasia | Fluorescence in situ hybridization | Chromosome 12 | genomics | histiocytoma | Bone | Immunoreactivity | Bone (cortical) | Chromosomes | Tumors | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, pp. e72182 - e72182
Neuroblastoma is a pediatric cancer of the peripheral nervous system in which structural chromosome aberrations are emblematic of aggressive tumors. In this... 
PATIENT DISRUPTS | REPLICATION | MULTIDISCIPLINARY SCIENCES | GENES | 17Q GAIN | SEQUENCING DATA | CELL-LINES | CANCER | CHROMOSOME BREAKPOINTS | MOLECULAR ANALYSIS | ALIGNMENT TOOL | Chromosome Breakpoints | Humans | Neuroblastoma - genetics | Gene Expression Regulation, Neoplastic | Child, Preschool | Molecular Sequence Data | Sequence Analysis, DNA | Sequence Homology, Nucleic Acid | DNA Copy Number Variations | Membrane Glycoproteins - genetics | Receptor Protein-Tyrosine Kinases - genetics | Acid Anhydride Hydrolases - genetics | Base Sequence | Chromosome Aberrations | Polymerase Chain Reaction | Cell Line, Tumor | Transcription, Genetic | Gene Rearrangement - genetics | Receptor-Like Protein Tyrosine Phosphatases, Class 2 - genetics | Neoplasm Proteins - genetics | Neuroblastoma - pathology | Translocation, Genetic - genetics | Genetic aspects | Neuroblastoma | RNA | Genes | Analysis | Biotechnology | Genomics | Insertion | Homology | Nervous system | Genomes | Chromosome rearrangements | Gene sequencing | Tumorigenesis | Chromosomes | Deoxyribonucleic acid--DNA | Knots | Peripheral nervous system | Breakpoints | Gene expression | Ribonucleic acid--RNA | Chromosome translocations | Cell lines | Non-homologous end joining | Aberration | Chromosome aberrations | Cancer | Tumors | Index Medicus | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2014, Volume 5, Issue 9, pp. 2688 - 2702
Journal Article
Oncotarget, 08/2019, Volume 10, Issue 48, pp. 4937 - 4950
Journal Article
PLoS ONE, 08/2013, Volume 8, Issue 8
Neuroblastoma is a pediatric cancer of the peripheral nervous system in which structural chromosome aberrations are emblematic of aggressive tumors. In this... 
Breakpoints
Journal Article
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