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1. Full Text Pediatric Rheumatology Collaborative Study Group - over four decades of pivotal clinical drug research in pediatric rheumatology
by Brunner, Hermine I and Rider, Lisa G and Kingsbury, Daniel J and Co, Dominic and Schneider, Rayfel and Goldmuntz, Ellen and Onel, Karen B and Giannini, Edward H and Lovell, Daniel J and Colbert, Robert and McNamara, James and Peng, Suzette and Yim, Sarah and PRCSG Advisory Council and for the PRCSG Advisory Council
Pediatric Rheumatology, ISSN 1546-0096, 07/2018, Volume 16, Issue 1, pp. 45 - 9
Importance: Specialized research networks are essential to achieve drug approvals for rare pediatric diseases. Such networks help realize the potential of... 
Clinical trials | PRCSG | Networks | Pediatrics | JIA | Drug approvals | SYSTEMIC-LUPUS-ERYTHEMATOSUS | JUVENILE IDIOPATHIC ARTHRITIS | PRELIMINARY DEFINITION | RHEUMATOLOGY | DISEASE-ACTIVITY | LONG-TERM SAFETY | INACTIVE DISEASE | QUALITY-OF-LIFE | USSR DOUBLE-BLIND | STANDARD METHODOLOGY | SEGMENT-II | Drugs | Analysis | Dosage and administration | Children | Research | Drug therapy | Pediatric research | Drug approval | Diseases
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2. Epipolymorphisms associated with the clinical outcome of autoimmune arthritis affect CD4+ T cell activation pathways
by Roberto Spreafico and Maura Rossetti and John W Whitaker and Wei Wang and Daniel J Lovell and Salvatore Albani
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 48, p. 13845
  Multifactorial diseases, including autoimmune juvenile idiopathic arthritis (JIA), result from a complex interplay between genetics and environment.... 
Immunotherapy | DNA methylation | Tumor necrosis factor-TNF | T cell receptors | Arthritis | Clinical outcomes | Polymorphism
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3. Full Text Multimetallic Catalysis Enabled Cross-Coupling of Aryl Bromides with Aryl Triflates
by Ackerman, Laura K.G and Lovell, Matthew M and Weix, Daniel J
Nature, ISSN 0028-0836, 8/2015, Volume 524, Issue 7566, pp. 454 - 457
Transition metal-catalyzed strategies for the formation of new C-C bonds have revolutionized the field of organic chemistry, enabling the efficient synthesis... 
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4. Describing the process and quantifying the outcomes of the Cuyahoga County sexual assault kit initiative
by Rachel Lovell and Misty Luminais and Daniel J Flannery and Richard Bell and Brett Kyker
Journal of Criminal Justice, ISSN 0047-2352, 07/2018, Volume 57, p. 106
Purpose: This is a case study of an early adopter jurisdiction addressing its large number of previously unsubmitted sexual assault kits (SAKs) and the first... 
Policy making | Case studies | Jurisdiction | Assaults | Rape | DNA | Sex offenders | Criminal proceedings | Repeated | Forecasting | Sexual assault
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5. Full Text Multimetallic catalysed cross-coupling of aryl bromides with aryl triflates
by Ackerman, Laura K. G and Lovell, Matthew M and Weix, Daniel J
Nature, ISSN 0028-0836, 08/2015, Volume 524, Issue 7566, pp. 454 - 457
The advent of transition-metal catalysed strategies for forming new carbon-carbon bonds has revolutionized the field of organic chemistry, enabling the... 
HALIDES | TRANSITION | IODOARENES | MULTIDISCIPLINARY SCIENCES | ARYLATION | UNACTIVATED ARENES | BIARYLS | COBALT | Phosphines - chemistry | Nickel - chemistry | Propane - analogs & derivatives | Bromides - chemistry | Substrate Specificity | Indicators and Reagents | Catalysis | Hydrogen - chemistry | Palladium - chemistry | Carbon - chemistry | Propane - chemistry | Bromides | Arylation | Research | Properties | Chemical research | Hydrocarbons | Ligands | Fluorides | Potassium
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6. Full Text Abatacept in children with juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled withdrawal trial
by Ruperto, Nicolino, MD and Lovell, Daniel J, Prof and Quartier, Pierre, MD and Paz, Eliana, MD and Rubio-Pérez, Nadina, MD and Silva, Clovis A, MD and Abud-Mendoza, Carlos, MD and Burgos-Vargas, Ruben, Prof and Gerloni, Valeria, MD and Melo-Gomes, Jose A, MD and Saad-Magalhães, Claudia, MD and Sztajnbok, Flavio, MD and Goldenstein-Schainberg, Claudia, MD and Scheinberg, Morton, MD and Penades, Immaculada Calvo, MD and Fischbach, Michael, MD and Orozco, Javier, MD and Hashkes, Philip J, MD and Hom, Christine, MD and Jung, Lawrence, MD and Lepore, Loredana, MD and Oliveira, Sheila, MD and Wallace, Carol A, Prof and Sigal, Leonard H, Prof and Block, Alan J, PhD and Covucci, Allison, MS and Martini, Alberto, Prof and Giannini, Edward H, Prof and PRCSG and PRINTO and Pediatric Rheumatology Collaborative Study Group and Paediatric Rheumatology INternational Trials Organization
Lancet, The, ISSN 0140-6736, 2008, Volume 372, Issue 9636, pp. 383 - 391
Summary Background Some children with juvenile idiopathic arthritis either do not respond, or are intolerant to, treatment with disease-modifying antirheumatic... 
Internal Medicine | RHEUMATOID-ARTHRITIS | MEDICINE, GENERAL & INTERNAL | INHIBITION | EFFICACY | METHOTREXATE | PRELIMINARY DEFINITION | QUALITY-OF-LIFE | ETANERCEPT | Severity of Illness Index | Double-Blind Method | Humans | Male | Treatment Outcome | Arthritis, Juvenile - drug therapy | Abatacept | Arthritis, Juvenile - classification | Adolescent | Range of Motion, Articular | Antirheumatic Agents - adverse effects | Immunoconjugates - therapeutic use | Female | Infusions, Intravenous | Child | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Antirheumatic Agents - therapeutic use | Immunoconjugates - adverse effects | Drug therapy | Juvenile arthritis | Research | Hospitals | Rheumatology | Data collection | Arthritis | Pharmaceutical industry | Autoimmune diseases | Patients | Placebo effect | Quality of life
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7. Full Text Neurotypical Peers are Less Willing to Interact with Those with Autism based on Thin Slice Judgments
by Sasson, Noah J and Faso, Daniel J and Nugent, Jack and Lovell, Sarah and Kennedy, Daniel P and Grossman, Ruth B
Scientific Reports, ISSN 2045-2322, 02/2017, Volume 7, Issue 1, p. 40700
Individuals with autism spectrum disorder (ASD), including those who otherwise require less support, face severe difficulties in everyday social interactions.... 
INDIVIDUALS | EXPRESSIONS | 1ST IMPRESSIONS | METAANALYSIS | ADOLESCENTS | MULTIDISCIPLINARY SCIENCES | SPECTRUM DISORDERS | ADULTS | HIGH-FUNCTIONING AUTISM | CHILDREN | PERCEPTIONS | Humans | Middle Aged | Child, Preschool | Peer Group | Infant | Male | Autism Spectrum Disorder - psychology | Case-Control Studies | Emotions | Young Adult | Social Behavior | Adult | Female | Speech | Interpersonal Relations | Autism Spectrum Disorder - diagnosis | Judgment | Autism | Visual stimuli | Social interactions | Social behavior | Social interaction | Cognitive ability
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8. Full Text Adalimumab with or without Methotrexate in Juvenile Rheumatoid Arthritis
by Lovell, Daniel J and Ruperto, Nicolino and Goodman, Steven and Reiff, Andreas and Jung, Lawrence and Jarosova, Katerina and Nemcova, Dana and Mouy, Richard and Sandborg, Christy and Bohnsack, John and Elewaut, Dirk and Foeldvari, Ivan and Gerloni, Valeria and Rovensky, Jozef and Minden, Kirsten and Vehe, Richard K and Weiner, L. Wagner and Horneff, Gerd and Huppertz, Hans-Iko and Olson, Nancy Y and Medich, John R and Carcereri-De-Prati, Roberto and McIlraith, Melissa J and Giannini, Edward H and Martini, Alberto and Pediat Rheumatology Collaborative and Pediat Rheumatology Int Trials Org and Pediatric Rheumatology Collaborative Study Group and Pediatric Rheumatology International Trials Organisation
The New England Journal of Medicine, ISSN 0028-4793, 08/2008, Volume 359, Issue 8, pp. 810 - 820
In this randomized, placebo-controlled trial of 133 children with polyarticular juvenile rheumatoid arthritis who had a response to a 16-week course of... 
TRIAL | MEDICINE, GENERAL & INTERNAL | THERAPY | EFFICACY | SAFETY | PLUS METHOTREXATE | DOUBLE-BLIND | IMPROVEMENT | IDIOPATHIC ARTHRITIS | ETANERCEPT | CHILDREN | Double-Blind Method | Antirheumatic Agents - administration & dosage | Humans | Antibodies, Monoclonal - adverse effects | Child, Preschool | Antibodies, Monoclonal - therapeutic use | Male | Methotrexate - therapeutic use | Arthritis, Juvenile - drug therapy | Antibodies, Monoclonal, Humanized | Antibodies, Monoclonal - administration & dosage | Adolescent | Antirheumatic Agents - adverse effects | Female | Adalimumab | Drug Therapy, Combination | Child | Antibodies, Monoclonal - immunology | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Antirheumatic Agents - therapeutic use | Rheumatism | Pharmaceutical industry | Drug dosages | Rheumatoid arthritis | Rheumatic diseases
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9. Full Text The authors reply
by Lovell, Daniel J and Ruperto, Nicolino
New England Journal of Medicine, ISSN 0028-4793, 12/2008, Volume 359, Issue 23, pp. 2496 - 2497
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10. Full Text Overview of the JET results in support to ITER
by Litaudon, X and Abduallev, S and Abhangi, M and Abreu, P and Afzal, M and Aggarwal, K.M and Ahlgren, T and Ahn, J.H and Aho-Mantila, L and Aiba, N and Airila, M and Albanese, R and Aldred, V and Alegre, D and Alessi, E and Aleynikov, P and Alfier, A and Alkseev, A and Allinson, M and Alper, B and Alves, E and Ambrosino, G and Ambrosino, R and Amicucci, L and Amosov, V and Andersson Sundén, E and Angelone, M and Anghel, M and Angioni, C and Appel, L and Appelbee, C and Arena, P and Ariola, M and Arnichand, H and Arshad, S and Ash, A and Ashikawa, N and Aslanyan, V and Asunta, O and Auriemma, F and Austin, Y and Avotina, L and Axton, M.D and Ayres, C and Bacharis, M and Baciero, A and Baiáo, D and Bailey, S and Baker, A and Balboa, I and Balden, M and Balshaw, N and Bament, R and Banks, J.W and Baranov, Y.F and Barnard, M.A and Barnes, D and Barnes, M and Barnsley, R and Baron Wiechec, A and Barrera Orte, L and Baruzzo, M and Basiuk, V and Bassan, M and Bastow, R and Batista, A and Batistoni, P and Baughan, R and Bauvir, B and Baylor, L and Bazylev, B and Beal, J and Beaumont, P.S and Beckers, M and Beckett, B and Becoulet, A and Bekris, N and Beldishevski, M and Bell, K and Belli, F and Bellinger, M and Belonohy, É and Ben Ayed, N and Benterman, N.A and Bergsåker, H and Bernardo, J and Bernert, M and Berry, M and Bertalot, L and Besliu, C and Beurskens, M and Bieg, B and Bielecki, J and Biewer, T and Bigi, M and Bílková, P and Binda, F and Bisoffi, A and Bizarro, J.P.S and Björkas, C and ... and Jet Contributors and JET Contributors and Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States) and Fusionsplasmafysik and Skolan för elektro- och systemteknik (EES) and KTH
Nuclear Fusion, ISSN 0029-5515, 06/2017, Volume 57, Issue 10, p. 102001
The 2014-2016 JET results are reviewed in the light of their significance for optimising the ITER research plan for the active and non-active operation. More... 
fusion | JET | ITER | plasma | COLLISIONALITY | DISRUPTION PREDICTION | ELMY H-MODES | PHYSICS, FLUIDS & PLASMAS | PEDESTAL | PLASMA-FACING COMPONENTS | OPERATION | CARBON WALL | DENSITY PEAKING | EDGE LOCALIZED MODES | DIAGNOSTICS | Mechanics | Engineering Sciences | Fluids mechanics | 70 PLASMA PHYSICS AND FUSION TECHNOLOGY | Fusion, Plasma and Space Physics | Fysik | Fusion, plasma och rymdfysik | Physical Sciences | Naturvetenskap | Natural Sciences
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11. Full Text Rilonacept for colchicine-resistant or -intolerant familial Mediterranean fever: A randomized trial
by Hashkes, Philip J and Spalding, Steven J and Giannini, Edward H and Huang, Bin and Johnson, Anne and Park, Grace and Barron, Karyl S and Weisman, Michael H and Pashinian, Noune and Reiff, Andreas O and Samuels, Jonathan and Wright, Dowain A and Kastner, Daniel L and Lovell, Daniel J
Annals of Internal Medicine, ISSN 0003-4819, 10/2012, Volume 157, Issue 8, pp. 533 - 541
Background: Currently, there is no proven alternative therapy for patients with familial Mediterranean fever (FMF) that is resistant to or intolerant of... 
MEDICINE, GENERAL & INTERNAL | THERAPY | PROTEIN | EFFICACY | AMYLOIDOSIS | DOUBLE-BLIND | PATIENT | ANAKINRA | MUTATIONS | PYRIN | ADOLESCENT | Double-Blind Method | Recombinant Fusion Proteins - adverse effects | Colchicine - therapeutic use | Humans | Recombinant Fusion Proteins - therapeutic use | Child, Preschool | Receptors, Interleukin-1 Type I - therapeutic use | Male | Treatment Outcome | Colchicine - adverse effects | Familial Mediterranean Fever - drug therapy | Young Adult | Adolescent | Adult | Female | Child | Drug Resistance | Interleukin-1 | Familial Mediterranean fever | Research | Drug therapy
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12. Full Text Subcutaneous golimumab for children with active polyarticular-course juvenile idiopathic arthritis: results of a multicentre, double-blind, randomised-withdrawal trial
by Brunner, Hermine I and Ruperto, Nicolino and Tzaribachev, Nikolay and Horneff, Gerd and Chasnyk, Vyacheslav G and Panaviene, Violeta and Abud-Mendoza, Carlos and Reiff, Andreas and Alexeeva, Ekaterina and Rubio-Pérez, Nadina and Keltsev, Vladimir and Kingsbury, Daniel J and del Rocio Maldonado Velázquez, Maria and Nikishina, Irina and Silverman, Earl D and Joos, Rik and Smolewska, Elzbieta and Bandeira, Márcia and Minden, Kirsten and van Royen-Kerkhof, Annet and Emminger, Wolfgang and Foeldvari, Ivan and Lauwerys, Bernard R and Sztajnbok, Flavio and Gilmer, Keith E and Xu, Zhenhua and Leu, Jocelyn H and Kim, Lilianne and Lamberth, Sarah L and Loza, Matthew J and Lovell, Daniel J and Martini, Alberto and Paediat Rheumatology Int and Pediat Rheumatology Collaborative and Paediatric Rheumatology International Trials Organisation (PRINTO) and the Pediatric Rheumatology Collaborative Study Group (PRCSG)
Annals of the Rheumatic Diseases, ISSN 0003-4967, 01/2018, Volume 77, Issue 1, pp. 21 - 29
ObjectiveThis report aims to determine the safety, pharmacokinetics (PK) and efficacy of subcutaneous golimumab in active polyarticular-course juvenile... 
Immunology | biologics | Rheumatology | Biochemistry, Genetics and Molecular Biology(all) | juvenile idiopathic arthritis | Immunology and Allergy | anti-tumour necrosis factor | golimumab | RHEUMATOID-ARTHRITIS | CRITERIA | METHOTREXATE | PRELIMINARY DEFINITION | SELECT CATEGORIES | RHEUMATOLOGY | DISEASE-ACTIVITY | REMISSION | Double-Blind Method | Antirheumatic Agents - administration & dosage | Arthritis - pathology | Humans | Child, Preschool | Male | Treatment Outcome | Remission Induction | Arthritis, Juvenile - drug therapy | Symptom Flare Up | Antibodies, Monoclonal - administration & dosage | Injections, Subcutaneous | Adolescent | Arthritis - drug therapy | Female | Methotrexate - administration & dosage | Drug Therapy, Combination | Child | Arthritis, Juvenile - pathology | Pediatrics | Clinical trials | Arthritis | Patients | Collaboration | Rheumatoid arthritis | Tumor necrosis factor-TNF | Remission | Children | Safety | Pharmacokinetics | Methotrexate | Drug dosages | Clinical and Epidemiological Research | 2311 | 1507 | 1506
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13. Full Text Long-term efficacy and safety of infliximab plus methotrexate for the treatment of polyarticular course juvenile rheumatoid arthritis: Findings from an open-label treatment extension (Annals of the Rheumatic Diseases (2010) 69, 3 (585-587))
by Ruperto, Nicolino and Lovell, Daniel J and Cuttica, Ruben
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2012, Volume 71, Issue 6, p. 1106
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14. Full Text Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis
by Ruperto, Nicolino and Brunner, Hermine I and Quartier, Pierre and Constantin, Tamás and Wulffraat, Nico and Horneff, Gerd and Brik, Riva and McCann, Liza and Kasapcopur, Ozgur and Rutkowska-Sak, Lidia and Schneider, Rayfel and Berkun, Yackov and Calvo, Inmaculada and Erguven, Muferet and Goffin, Laurence and Hofer, Michael and Kallinich, Tilmann and Oliveira, Sheila K and Uziel, Yosef and Viola, Stefania and Nistala, Kiran and Wouters, Carine and Cimaz, Rolando and Ferrandiz, Manuel A and Flato, Berit and Gamir, Maria Luz and Kone-Paut, Isabelle and Grom, Alexei and Magnusson, Bo and Ozen, Seza and Sztajnbok, Flavio and Lheritier, Karine and Abrams, Ken and Kim, Dennis and Martini, Alberto and Lovell, Daniel J and PRCSG and PRINTO
The New England Journal of Medicine, ISSN 0028-4793, 12/2012, Volume 367, Issue 25, pp. 2396 - 2406
In two placebo-controlled trials, canakinumab, an anti-interleukin-1β monoclonal antibody, achieved a response, prevented flares, and allowed glucocorticoid... 
RHEUMATOID-ARTHRITIS | CRITERIA | MEDICINE, GENERAL & INTERNAL | RECEPTOR ANTAGONIST ANAKINRA | EFFICACY | DOUBLE-BLIND | PRELIMINARY DEFINITION | FOLLOW-UP | CLASSIFICATION | SELECT CATEGORIES | CHILDREN | Glucocorticoids - therapeutic use | Double-Blind Method | Humans | Antibodies, Monoclonal - adverse effects | Kaplan-Meier Estimate | Child, Preschool | Antibodies, Monoclonal - therapeutic use | Male | Thrombocytopenia - chemically induced | Methotrexate - therapeutic use | Infection - chemically induced | Arthritis, Juvenile - drug therapy | Macrophage Activation Syndrome - etiology | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Adolescent | Arthritis, Juvenile - complications | Female | Drug Therapy, Combination | Neutropenia - chemically induced | Child | Interleukin-1beta - antagonists & inhibitors | Drugs | Dose-response relationship (Biochemistry) | Product/Service Evaluations | Drug therapy | Juvenile arthritis | Pediatrics | Cytokines | Fever | Rheumatology | Index Medicus | Abridged Index Medicus
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