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1. Full Text EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC
by Krishnamoorthy, Gnana P and Davidson, Natalie R and Leach, Steven D and Zhao, Zhen and Lowe, Scott W and Lee, Gina and Landa, Iňigo and Nagarajah, James and Saqcena, Mahesh and Singh, Kamini and Wendel, Hans-Guido and Dogan, Snjezana and Tamarapu, Prasanna P and Blenis, John and Ghossein, Ronald A and Knauf, Jeffrey A and Rätsch, Gunnar and Fagin, James A
Cancer discovery, ISSN 2159-8274, 02/2019, Volume 9, Issue 2, pp. 264 - 281
Translation initiation is orchestrated by the cap binding and 43S preinitiation complexes (PIC). Eukaryotic initiation factor 1A (EIF1A) is essential for... 
TRANSFORMATION | CELLS | ACTIVATION | ONCOLOGY | PATHWAY | START CODON SELECTION | GENE-EXPRESSION | TRANSLATION | STRESS | CANCER | BINDING
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2. Full Text Genome-wide associations for birth weight and correlations with adult disease
by Horikoshi, Momoko and Beaumont, R.N and Day, Felix and Warrington, Nicole and Kooijman, Marjolein and Fernandez-Tajes, Juan and Feenstra, Bjarke and Van Zuydam, Natalie R and Gaulton, Kyle and Grarup, Niels and Bradfield, Jonathan and Strachan, David and Li-Gao, R and Ahluwalia, Tarunveer Singh and Kreiner, E and Rueedi, R and Lyytikäinen, Leo-Pekka and Cousminer, Diana and Wu, Ying and Thiering, Elisabeth and Wang, Carol A and Have, Christian T and Hottenga, Jouke Jan and Vilor-Tejedor, Natàlia and Joshi, Peter and Boh, E.T.H and Ntalla, Ioanna and Pitkanen, Niina and Mahajan, Anubha and Leeuwen, Elisa and Joro, Raimo and Lagou, Vasiliki and Nodzenski, Michael and Diver, L.A and Zondervan, Krina and Bustamante, Mariona and Marques-Vidal, Peo and Mercader, Josep and Bennett, Amanda and Rahmioglu, Nilufer and Nyholt, Dale and Ma, R.C.W and Tam, C.H.T and Tam, W.H and Ganesh, Santhi and Rooij, Frank and Jones, Samuel E and Loh, Po-Ru and Ruth, Katherine S and Tuke, M.A and Tyrrell, A.W.R and Wood, Anew and Yaghootkar, Hanieh and Scholtens, Denise M and Paternoster, Lavinia and Prokopenko, Inga and Kovacs, Peter and Atalay, Mustafa and Willems, Sara and Panoutsopoulou, K and Wang, Xu and Carstensen, Lisbeth and Geller, Frank and Schraut, K.E and Murcia, Mario and Beijsterveldt, Toos and Willemsen, Gonneke and Appel, E.V.R and Fonvig, C.E and Trier, C and Tiesler, C.M.T and Standl, Eberhard and Kutalik, Zoltán and Bonàs-Guarch, Silvia and Hougaard, David and Sánchez, F and Torrents, David and Waage, Johannes and Hollegaard, Mads V and Haan, Hugoline and Rosendaal, Frits and Medina-Gomez, C and Ring, Susan and Hemani, G and Mcmahon, George and Robertson, Neil and Groves, Christopher and Langenberg, Claudia and Luan, Jian'An and Scott, Robert and Zhao, Jing Hua and Mentch, Frank and MacKenzie, S.M and Reynolds, Rebecca and Lowe, William and Tönjes, Anke and Stumvoll, Michael and Lindi, Virpi and Lakka, Timo and Duijn, Cornelia and ... and EGG Consortium and CHARGE Consortium Hematology Worki and CHARGE Consortium Hematology Working Group and Early Growth Genetics (EGG) Consortium
Nature: international weekly journal of science, ISSN 0028-0836, 01/2016, Volume 538, Issue 7624, pp. 248 - 252
textabstractBirth weight (BW) has been shown to be influenced by both fetal and maternal factors and in observational studies is reproducibly associated with... 
HUMAN HEIGHT | POPULATION | ALTITUDE ADAPTATION | METAANALYSIS | VARIANTS | GENOTYPE IMPUTATION | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | LOCI | TRAITS | BLOOD-PRESSURE | Blood Pressure - genetics | Anthropometry | Diabetes Mellitus, Type 2 - genetics | Humans | Fetus - metabolism | Genetic Loci - genetics | Male | Aging - genetics | Glycogen - biosynthesis | Adult | Female | Genetic Predisposition to Disease | Genome-Wide Association Study | Datasets as Topic | Signal Transduction | Chromatin Assembly and Disassembly | Genotype | Birth Weight - genetics | Genomic Imprinting - genetics | Insulin - metabolism | Phenotype | Coronary Artery Disease - genetics | Glucose - metabolism | Genetic Variation - genetics | Cohort Studies | Genome-wide association studies | Birth size | Metabolic diseases | Genetic aspects | Birth weight | Cardiovascular diseases | Health aspects | Risk factors | Studies | Genomes | Disease | Correlation analysis
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3. Full Text Linkage maps of the Atlantic salmon (Salmo salar) genome derived from RAD sequencing
by Gonen, Serap and Lowe, Natalie R and Cezard, Timothé and Gharbi, Karim and Bishop, Stephen C and Houston, Ross D
BMC Genomics, ISSN 1471-2164, 02/2014, Volume 15, Issue 1, pp. 166 - 166
Background: Genetic linkage maps are useful tools for mapping quantitative trait loci (QTL) influencing variation in traits of interest in a population.... 
RECOMBINATION | DE-NOVO | RAINBOW-TROUT | EVOLUTION | SNP DISCOVERY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENES | GENETICS & HEREDITY | MARKERS | FISHES | HYBRIDIZATION | REVEALS | Gene Duplication | Reproducibility of Results | Physical Chromosome Mapping | Genomics | Synteny | Genotype | Male | Chromosome Mapping | Genetic Markers | Sequence Analysis, DNA | Salmo salar - genetics | Animals | Recombination, Genetic | Female | Polymorphism, Single Nucleotide | Genome | Quantitative Trait Loci | Microsatellite Repeats | Genetic Linkage | Quantitative genetics | Genetic aspects | Linkage (Genetics) | Research | Salmon | Analysis | Fishes | Genes | Genetic research | Genomes | Single nucleotide polymorphisms | Nucleotide sequencing | DNA sequencing | Studies | Enzymes | Fish | Software | Males | Females | Aquaculture
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4. Full Text Development and validation of a high density SNP genotyping array for Atlantic salmon (Salmo salar)
by Houston, Ross D and Taggart, John B and Cézard, Timothé and Bekaert, Michaël and Lowe, Natalie R and Downing, Alison and Talbot, Richard and Bishop, Stephen C and Archibald, Alan L and Bron, James E and Penman, David J and Davassi, Alessandro and Brew, Fiona and Tinch, Alan E and Gharbi, Karim and Hamilton, Alastair
BMC Genomics, ISSN 1471-2164, 02/2014, Volume 15, Issue 1, pp. 90 - 90
Background: Dense single nucleotide polymorphism (SNP) genotyping arrays provide extensive information on polymorphic variation across the genome of species of... 
Array | Next-generation sequencing | Genome duplication | Genomics | Salmo salar | Single nucleotide polymorphism, SNP | Atlantic salmon | Mapping | Polymorphism | LINKAGE MAP | RECOMBINATION | READ ALIGNMENT | RAINBOW-TROUT | INFECTIOUS PANCREATIC NECROSIS | RAD MARKERS | DISCOVERY | MAJOR QTL | SNP | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENOMIC SELECTION | GENETICS & HEREDITY | Single nucleotide polymorphism | TROUT ONCORHYNCHUS-MYKISS | Gene Library | Gene Frequency | Genotype | Male | Salmo salar - genetics | Haploidy | Animals | Alleles | Contig Mapping | High-Throughput Nucleotide Sequencing | Polymorphism, Single Nucleotide | Genome | Cluster Analysis | Genetic Linkage | Animal genetics | Fish-culture | Genetic research | Genetic aspects | Research | Single nucleotide polymorphisms | Aquaculture | RNA sequencing | Usage | RNA | Salmon | Fishes | Aquaculture industry | Genomes | Chromosomes | Studies | Fish
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5. Full Text Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy
by Scholtens, Denise M and Muehlbauer, Michael J and Daya, Natalie R and Stevens, Robert D and Dyer, Alan R and Lowe, Lynn P and Metzger, Boyd E and Newgard, Christopher B and Bain, James R and Lowe, William L and HAPO Study Cooperative Res Grp and HAPO Study Cooperative Research Group and for the HAPO Study Cooperative Research Group
Diabetes Care, ISSN 0149-5992, 01/2014, Volume 37, Issue 1, pp. 158 - 166
OBJECTIVETo characterize metabolites across the range of maternal glucose by comparing metabolomic profiles of mothers with high and low fasting plasma glucose... 
BIOMARKERS | MATERNAL URINE | INSULIN-RESISTANCE | AMINO-ACIDS | ENDOCRINOLOGY & METABOLISM | WEIGHT-LOSS | DISORDERS | GESTATIONAL DIABETES-MELLITUS | IDENTIFICATION | GLUCOSE-TOLERANCE | LIPIDS | Glucose Tolerance Test | Humans | Metabolomics - methods | Mothers | Triglycerides - metabolism | Hyperglycemia - metabolism | Pregnancy | Amino Acids - metabolism | 3-Hydroxybutyric Acid - metabolism | Adult | Female | Pregnancy Complications - metabolism | Blood Glucose - metabolism | C-Peptide - metabolism | Infant, Newborn | Pregnancy Outcome | Food | Glucose metabolism | Hyperglycemia | Metabolites | Pregnant women | Analysis | Amino acids | Glucose | Glucose tolerance tests | Dextrose | Epidemiology | Health Services Research
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6. Full Text Characterisation of QTL-linked and genome-wide restriction site-associated DNA (RAD) markers in farmed Atlantic salmon
by Houston, Ross D and Davey, John W and Bishop, Stephen C and Lowe, Natalie R and Mota-Velasco, Jose C and Hamilton, Alastair and Guy, Derrick R and Tinch, Alan E and Thomson, Marian L and Blaxter, Mark L and Gharbi, Karim and Bron, James E and Taggart, John B
BMC Genomics, ISSN 1471-2164, 06/2012, Volume 13, Issue 1, pp. 244 - 244
Background: Restriction site-associated DNA sequencing (RAD-Seq) is a genome complexity reduction technique that facilitates large-scale marker discovery and... 
Paralogous sequence variant | Recombination | Atlantic salmon | Infectious pancreatic necrosis | Single nucleotide polymorphism | RAD sequencing | Aquaculture | LINKAGE MAP | RAINBOW-TROUT | SUSCEPTIBILITY | CONFIRMATION | TRAIT | DISCOVERY | MAJOR QTL | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | RESISTANCE | SALAR REVEALS | Animals | Genetic Markers - genetics | Alleles | Chromosome Mapping | Polymorphism, Single Nucleotide | Genome | Quantitative Trait Loci | Fish Diseases - genetics | Microsatellite Repeats | Genetic Linkage | Pancreatic Diseases - genetics | Salmo salar - genetics | Quantitative trait loci | Genetic aspects | Genomes | Research | Fish-culture | Enzymes | Salmon | Genomics | Quantitative genetics | Genetic markers | Analysis | Fishes | DNA | Aquaculture industry | Single nucleotide polymorphisms | Nucleotide sequencing | Applications programming | DNA sequencing | Fish | Trout | Nucleotide sequence | Breeding | Mortality | Data processing | Single-nucleotide polymorphism | Survival | Genotyping | genomics | Gene mapping | Genotypes
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7. Full Text Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
by Warrington, Nicole M and Beaumont, Robin N and Horikoshi, Momoko and Day, Felix R and Helgeland, Øyvind and Laurin, Charles and Bacelis, Jonas and Peng, Shouneng and Hao, Ke and Feenstra, Bjarke and Wood, Anew R and Mahajan, Anubha and Tyrrell, Jessica and Robertson, Neil R and Rayner, N. William and Qiao, Zhen and Moen, Gunn-Helen and Vaudel, Marc and Marsit, Carmen J and Chen, Jia and Nodzenski, Michael and Schnurr, Theresia M and Zafarmand, Mohammad H and Bradfield, Jonathan P and Grarup, Niels and Kooijman, Marjolein N and Li-Gao, Ruifang and Geller, Frank and Ahluwalia, Tarunveer S and Paternoster, Lavinia and Rueedi, Rico and Huikari, Ville and Hottenga, Jouke-Jan and Lyytikäinen, Leo-Pekka and Cavadino, Alana and Metrustry, Sarah and Cousminer, Diana L and Wu, Ying and Thiering, Elisabeth and Wang, Carol A and Have, Christian T and Vilor-Tejedor, Natalia and Joshi, Peter K and Painter, Jodie N and Ntalla, Ioanna and van Leeuwen, Elisabeth M and van Kampen, Antoine H. C and van Schaik, Barbera D. C and Rosendaal, Frits R and Vrijkotte, Tanja G. M and EGG Consortium and Institutionen för kliniska vetenskaper, Avdelningen för obstetrik och gynekologi and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Institute of Clinical Sciences, Department of Obstetrics and Gynecology and Sahlgrenska Academy
Nature genetics, ISSN 1061-4036, 2019, Volume 51, Issue 5, pp. 804 - 814
Birth weight variation is influenced by fetal and maternal genetic and non-genetic factors, and has been reproducibly associated with future cardio-metabolic... 
DIABETES-MELLITUS | ORIGINS | GROWTH | DISEASE | GENETICS & HEREDITY | MENDELIAN RANDOMIZATION | LD SCORE REGRESSION | IDENTIFICATION | ASSOCIATION | BLOOD-PRESSURE | LIFE | Maternal Inheritance - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Blood Pressure - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Risk Factors | Male | Maternal-Fetal Exchange - genetics | Birth Weight - genetics | Body Height - genetics | Pregnancy | Heart Diseases - etiology | Metabolic Diseases - etiology | Metabolic Diseases - genetics | Adult | Diabetes Mellitus, Type 2 - etiology | Female | Fetal Development - genetics | Models, Genetic | Polymorphism, Single Nucleotide | Heart Diseases - genetics | Infant, Newborn | Hypertension | Hyperglycemia | Prenatal influences | Growth | Birth size | Fetus | Genetic aspects | Birth weight | Health aspects | Risk factors | Disease | Fetuses | Genomes | Metabolism | Risk analysis | Intrauterine exposure | Mothers | Weight | Meta-analysis | Childbirth & labor | Genetic effects | Progeny | Offspring | Alleles | Gene loci | Blood pressure | Diabetes | Genetic factors | Bioinformatics | Genotypes | Clinical Medicine | Obstetrics, Gynecology and Reproductive Medicine | Reproduktionsmedicin och gynekologi | Klinisk medicin
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8. Full Text Balancing selection at a premature stop mutation in the myostatin gene underlies a recessive leg weakness syndrome in pigs
by Matika, Oswald and Robledo, Diego and Pong-Wong, Ricardo and Bishop, Stephen C and Riggio, Valentina and Finlayson, Heather and Lowe, Natalie R and Hoste, Annabelle E and Walling, Grant A and Del-Pozo, Jorge and Archibald, Alan L and Woolliams, John A and Houston, Ross D
PLoS genetics, ISSN 1553-7404, 01/2019, Volume 15, Issue 1, p. e1007759
Balancing selection provides a plausible explanation for the maintenance of deleterious alleles at moderate frequency in livestock, including lethal recessives... 
LANDRACE | QUANTITATIVE TRAIT LOCI | ARTIFICIAL SELECTION | DUROC | BOARS | OSTEOCHONDROSIS | GENETICS & HEREDITY | PROMOTER REGION | MUSCLE | GENERATION | Gene mutations | Swine | Myostatin | Genetic aspects | Health aspects | Chromosomes | Risk factors | Diseases | Phenotypes | Nonsense mutation | Stop codon | Heredity | Genomes | Leg | Hogs | Hypotheses | Gene frequency | Cattle | Alleles | Genetic engineering | Livestock | Mutation | Gene mapping | Chromosome 15 | Bioinformatics | Hyperthermia | Genotypes
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9. Full Text Sequencing and Characterisation of an Extensive Atlantic Salmon (Salmo salar L.) MicroRNA Repertoire
by Bekaert, Michaël and Lowe, Natalie R and Bishop, Stephen C and Bron, James E and Taggart, John B and Houston, Ross D
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e70136
Atlantic salmon (Salmo salar L.), a member of the family Salmonidae, is a totemic species of ecological and cultural significance that is also economically... 
CELLS | ZEBRAFISH | BIOGENESIS | ANNOTATION | MULTIDISCIPLINARY SCIENCES | GENES | TARGETS | ANIMAL DEVELOPMENT | EXPRESSION | GENOME | PREDICTION | Animals | Base Sequence | Computational Biology | Gene Expression Regulation | Transcriptome | Conserved Sequence | Repetitive Sequences, Nucleic Acid | Gene Dosage | High-Throughput Nucleotide Sequencing | MicroRNAs - genetics | Genetic Markers | Salmo salar - genetics | MicroRNA | Salmon | Fishes | Genes | Genomics | Aquaculture industry | Genomes | Genetic aspects | Research | Genetic transcription | International economic relations | Post-transcription | Target recognition | Nucleotide sequence | Copy number | Trout | Gene regulation | Spatial discrimination | MiRNA | Fisheries | Zebrafish | Homology | Gene expression | Gene sequencing | Next-generation sequencing | Ribonucleic acids | Salmonids | Fish | Non-coding RNA | Species | Aquaculture
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10. Full Text Construction and annotation of a high density SNP linkage map of the Atlantic salmon (Salmo salar) genome
by Tsai, Hsin Y and Robledo, Diego and Lowe, Natalie R and Bekaert, Michael and Taggart, John B and Bron, James E and Houston, Ross D
G3: Genes, Genomes, Genetics, ISSN 2160-1836, 07/2016, Volume 6, Issue 7, pp. 2173 - 2179
High density linkage maps are useful tools for fine-scale mapping of quantitative trait loci, and characterization of the recombination landscape of a species'... 
Linkage map | Recombination | SNP array | RNA-Seq | Salmo salar | POPULATION | recombination | PREDICTION | GENE | ALIGNMENT | SEX-SPECIFIC RECOMBINATION | GENETICS & HEREDITY | RESISTANCE | GENERATION | WIDE ASSOCIATION | linkage map | SINGLE NUCLEOTIDE POLYMORPHISMS | REVEALS | Molecular Sequence Annotation | Genotype | Male | Genetic Loci | Genetic Markers | Salmo salar - genetics | Animals | Recombination, Genetic | Chromosome Mapping - methods | Female | Polymorphism, Single Nucleotide | Genome | Microsatellite Repeats | Genetic Linkage
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11. Full Text Development of a medium density combined-species SNP array for pacific and european oysters (Crassostrea gigas and Ostrea edulis)
by Gutierrez, Alejandro P and Turner, Frances and Gharbi, Karim and Talbot, Richard and Lowe, Natalie R and Peñaloza, Carolina and McCullough, Mark and Prodöhl, Paulo A and Bean, Tim P and Houston, Ross D
G3: Genes, Genomes, Genetics, ISSN 2160-1836, 07/2017, Volume 7, Issue 7, pp. 2209 - 2218
SNP arrays are enabling tools for high-resolution studies of the genetic basis of complex traits in farmed and wild animals. Oysters are of critical importance... 
Array | Pacific oyster | Flat oyster | Single nucleotide polymorphism (SNP) | Aquaculture | GENOTYPING ASSAY | TOOL SET | VALIDATION | MICROSATELLITE DNA MARKERS | EXPRESSED SEQUENCE TAGS | aquaculture | GENETIC-VARIATION | HATCHERY POPULATIONS | array | single nucleotide polymorphism (SNP) | GENETICS & HEREDITY | flat oyster | SINGLE NUCLEOTIDE POLYMORPHISMS | GENOME-WIDE ASSOCIATION | LINKAGE MAPS | Crassostrea - genetics | Polymorphism, Single Nucleotide |