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1. Full Text Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: a population-based surveillance in Spain
by Puig-Asensio, M and Padilla, B and Garnacho-Montero, J and Zaragoza, O and Aguado, J.M and Zaragoza, R and Montejo, M and Muñoz, P and Ruiz-Camps, I and Cuenca-Estrella, M and Almirante, B and on behalf of the CANDIPOP Project and GEIH-GEMICOMED (SEIMC) and REIPI and GEIH-GEMICOMED SEIMC and REIPI and CANDIPOP Project and GEIH-GEMICOMED (SEIMC)
Clinical microbiology and infection, ISSN 1198-743X, 04/2014, Volume 20, Issue 4, pp. O245 - O254
Antifungal resistance | early mortality | epidemiology | prognostic factors | surveillance | Candida bloodstream infections | Early mortality | Surveillance | Epidemiology | Prognostic factors | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Prevalence | Prognosis | Prospective Studies | Humans | Middle Aged | Child, Preschool | Infant | Male | Candidemia - mortality | Urban Population | Incidence | Young Adult | Candida - classification | Aged, 80 and over | Adult | Female | Child | Drug Resistance, Fungal | Risk Factors | Candidemia - epidemiology | Candida - isolation & purification | Epidemiological Monitoring | Candidemia - drug therapy | Spain - epidemiology | Adolescent | Survival Analysis | Aged | Candida - drug effects | Septic shock | Fluconazole | Health aspects | Analysis | Mortality | Index Medicus
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2. Full Text Clinical validation of blood/brain glutamate grabbing in acute ischemic stroke
: Blood/Brain Glutamate Grabbing
by da Silva-Candal, Andrés and Pérez-Díaz, Amparo and Santamaría, María and Correa-Paz, Clara and Rodríguez-Yáñez, Manuel and Ardá, Ana and Pérez-Mato, María and Iglesias-Rey, Ramón and Brea, José and Azuaje, Jhonny and Sotelo, Eddy and Sobrino, Tomás and Loza, M. Isabel and Castillo, José and Campos, Francisco
Annals of neurology, ISSN 0364-5134, 08/2018, Volume 84, Issue 2, pp. 260 - 273
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3. Full Text Epidemiology and prognosis of candidaemia in elderly patients
by Ramos‐Martínez, Antonio and Vicente‐López, Natalia and Sánchez‐Romero, Isabel and Padilla, Belén and Merino‐Amador, Paloma and Garnacho‐Montero, José and Ruiz‐Camps, Isabel and Montejo, Miguel and Salavert, Miguel and Mensa, José and Cuenca‐Estrella, Manuel and Muñoz, Patricia and Guinea, Jesús and Paño Pardo, José Ramón and García‐Rodríguez, Julio and Cerrada, Carlos García and Fortún, Jesús and Martín, Pilar and Gómez, Elia and Ryan, Pablo and Campelo, Carolina and Santos Gil, Ignacio and Buendía, Ventura and Gorricho, Beatriz Perez and Alonso, Mercedes and Sanz, Francisca Sanz and Aguado, José María and Romo, Fernando González and Gorgolas, Miguel and Gadea, Ignacio and Losa, Juan Emilio and Delgado‐Iribarren, Alberto and Romero, Yolanda and Zaragoza, Oscar and Rodriguez‐Baño, Jesús and Suarez, Ana Isabel and Loza, Ana and Aller García, Ana Isabel and Martín‐Mazuelos, Estrella and Pérez de Pipaón, Maite Ruiz and Ortiz, Carlos and Chávez, Mónica and Maroto, Fernando L and Salavert, Miguel and Pemán, Javier and Blanquer, José and Navarro, David and Camarena, Juan José and Zaragoza, Rafael and Abril, Vicente and Gimeno, Concepción and Hernáez, Silvia and Ezpeleta, Guillermo and Bereciartua, Elena and Hernández Almaraz, José L and Montejo, Miguel and Rivas, Rosa Ana and Ayarza, Rafael and Planes, Ana Mª and Almirante, Benito and Almela, Manel and Gurgui, Mercè and Sánchez‐Reus, Ferran and Martinez‐Montauti, Joaquin and Sierra, Montserrat and Horcajada, Juan Pablo and Sorli, Luisa and Gómez, Julià and Gené, Amadeu and Urrea, Mireia and Valerio, Maricela and Díaz‐Martín, Ana and Puchades, Francesc and Mularoni, Alessandra and CANDIPOP Project GEIH-GEMICOMED and Members of the CANDIPOP Project from GEIH-GEMICOMED (SEIMC) and REIPI and the Members of the CANDIPOP Project from GEIH-GEMICOMED (SEIMC) and REIPI
Mycoses, ISSN 0933-7407, 12/2017, Volume 60, Issue 12, pp. 808 - 817
aged | central venous catheters | mortality | candidaemia | antifungal agents | Life Sciences & Biomedicine | Dermatology | Mycology | Science & Technology | Candida - genetics | Prognosis | Prospective Studies | Humans | Middle Aged | Male | Candidemia - epidemiology | Candida - isolation & purification | Antifungal Agents - therapeutic use | Candidemia - diagnosis | Young Adult | Candida - classification | Spain - epidemiology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Candida - drug effects | Aged patients | Epidemiology | Analysis | Immunotherapy | Mortality | Middle age | Kidneys | Parenteral nutrition | Immunosuppressive agents | Catheters | Renal failure | Candidemia | Neutropenia | Geriatrics | Kidney transplantation | Index Medicus
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4. Full Text Targeting PDE10A GAF domain with small molecules: A way for allosteric modulation with anti-inflammatory effects
by García, Ana M and Brea, José and González-García, Alejandro and Pérez, Concepción and Cadavid, María Isabel and Loza, María Isabel and Martinez, Ana and Gil, Carmen
Molecules (Basel, Switzerland), ISSN 1420-3049, 09/2017, Volume 22, Issue 9, p. 1472
Allosteric modulators | GAF domain | Anti-inflammatory | CAMP | PDE10 inhibitors | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Phosphoric Diester Hydrolases - metabolism | Anti-Inflammatory Agents - pharmacology | Cell Survival | Allosteric Regulation | Models, Molecular | Nitrites - metabolism | Phosphoric Diester Hydrolases - chemistry | Animals | Anti-Inflammatory Agents - chemistry | Databases, Chemical | Lipopolysaccharides - pharmacology | Protein Binding | Protein Domains | Mice | Enzyme Activation | Phosphodiesterase Inhibitors - chemistry | Binding Sites | Allosteric properties | Antiinflammatory agents | Cyclic nucleotides | Cyclic GMP | Inflammation | Nucleotides | Modulators | Crystal structure | Phosphodiesterase | Lipopolysaccharides | Index Medicus | anti-inflammatory | cAMP | allosteric modulators
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5. Full Text Epidemiology and outcome of candidaemia in patients with oncological and haematological malignancies: results from a population-based surveillance in Spain
by Puig-Asensio, M and Ruiz-Camps, I and Fernández-Ruiz, M and Aguado, J.M and Muñoz, P and Valerio, M and Delgado-Iribarren, A and Merino, P and Bereciartua, E and Fortún, J and Cuenca-Estrella, M and Almirante, B and the CANDIPOP Project, GEIH-GEMICOMED (SEIMC), and REIPI and GEIH-GEMICOMED SEIMC and REIPI and CANDIPOP Project
Clinical microbiology and infection, ISSN 1198-743X, 05/2015, Volume 21, Issue 5, pp. 491.e1 - 491.e10
epidemiology | haematological malignancies | Candidiasis | fluconazole | Antifungal agents | cancer | drug resistance | Fluconazole | Drug resistance | Haematological malignancies | Epidemiology | Cancer | Infectious Diseases | Life Sciences & Biomedicine | Microbiology | Science & Technology | Prospective Studies | Humans | Middle Aged | Male | Candidemia - mortality | Antifungal Agents - therapeutic use | Young Adult | Candida - classification | Neoplasms - complications | Aged, 80 and over | Catheter-Related Infections - mortality | Adult | Female | Catheter-Related Infections - epidemiology | Candidemia - microbiology | Risk Factors | Treatment Outcome | Candidemia - epidemiology | Candida - isolation & purification | Catheter-Related Infections - drug therapy | Epidemiological Monitoring | Candidemia - drug therapy | Spain - epidemiology | Catheter-Related Infections - microbiology | Adolescent | Survival Analysis | Aged | Index Medicus
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6. Full Text Corticosteroid treatment in critically ill patients with severe influenza pneumonia: a propensity score matching study
by Moreno, Gerard and Rodríguez, Alejandro and Reyes, Luis F and Gomez, Josep and Sole-Violan, Jordi and Díaz, Emili and Bodí, María and Trefler, Sandra and Guardiola, Juan and Yébenes, Juan C and Soriano, Alex and Garnacho-Montero, José and Socias, Lorenzo and del Valle Ortíz, María and Correig, Eudald and Marín-Corral, Judith and Vallverdú-Vidal, Montserrat and Restrepo, Marcos I and Torres, Antoni and Martín-Loeches, Ignacio and GETGAG Study Grp and GETGAG Study Group and on behalf of the GETGAG Study Group
Intensive care medicine, ISSN 0342-4642, 9/2018, Volume 44, Issue 9, pp. 1470 - 1482
Pediatrics | Pain Medicine | Pneumonia | Emergency Medicine | Pneumology/Respiratory System | Corticosteroids | Medicine & Public Health | Influenza | Mortality | Intensive / Critical Care Medicine | ICU | Anesthesiology | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Critical Care - methods | Prospective Studies | Humans | Middle Aged | Pneumonia, Viral - drug therapy | Anti-Infective Agents - therapeutic use | Critical Illness | Male | Treatment Outcome | Influenza, Human - complications | Adrenal Cortex Hormones - therapeutic use | Propensity Score | Spain - epidemiology | Pneumonia, Viral - complications | Survival Analysis | Influenza, Human - mortality | Adult | Female | Pneumonia, Viral - mortality | Influenza, Human - drug therapy | APACHE | Complications and side effects | Bacterial pneumonia | Dosage and administration | Drug therapy | Medical research | Lung diseases, Obstructive | Care and treatment | Analysis | Medicine, Experimental | Septic shock | Spain | Corticoids | Therapy | Hematology | Lung diseases | Methylprednisolone | Patients | Asthma | Matching | Obstructive lung disease | Ventilation | Chronic obstructive pulmonary disease | Secondary analysis | Hazard assessment | Index Medicus | Original
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7. Full Text Initial Use of Echinocandins Does Not Negatively Influence Outcome in Candida parapsilosis Bloodstream Infection: A Propensity Score Analysis
by Mario Fernández-Ruiz and José María Aguado and Benito Almirante and David Lora-Pablos and Belén Padilla and Mireia Puig-Asensio and Miguel Montejo and Julio García-Rodríguez and Javier Pemán and Maite Ruiz Pérez de Pipaón and Manuel Cuenca-Estrella and GEIH-GEMICOMED SEIMC and REIPI and CANDIPOP Project and GEIH-GEMICOMED (SEIMC)
Clinical infectious diseases, ISSN 1058-4838, 5/2014, Volume 58, Issue 10, pp. 1413 - 1421
Antifungals | Health outcomes | Azoles | Hospitals | Infectious diseases | Infections | Candidemia | Fungal infections | ARTICLES AND COMMENTARIES | Blood culture | Central venous catheterization | Echinocandin | Propensity score | Treatment | Bloodstream infection | Candida parapsilosis | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Biological and medical sciences | Medical sciences | Bacterial diseases | Human bacterial diseases | Bacterial sepsis | Prospective Studies | Humans | Middle Aged | Infant | Male | Antifungal Agents - therapeutic use | Microbial Sensitivity Tests | Adult | Female | Drug Resistance, Fungal | Echinocandins - pharmacology | Antifungal Agents - pharmacology | Candidemia - microbiology | Risk Factors | Treatment Outcome | Candidemia - epidemiology | Candida - isolation & purification | Sequence Analysis, DNA | Spain | Propensity Score | Candidemia - drug therapy | Echinocandins - therapeutic use | Aged | Candida - drug effects | Population Surveillance | Echinocandins | Septic shock | Usage | Health aspects | DNA | Testing | Bacteria | Regression analysis | Deoxyribonucleic acid--DNA | Risk factors | Index Medicus
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8. Pharmacological tools based on imidazole scaffold proved the utility of PDE10A inhibitors for Parkinson's disease
by García, Ana M and Salado, Irene G and Perez, Daniel I and Brea, José and Morales-García, Jose A and González-García, Alejandro and Cadavid, María Isabel and Loza, María Isabel and Luque, Francisco Javier and Perez-Castillo, Ana and Martinez, Ana and Gil, Carmen
Future medicinal chemistry, ISSN 1756-8919, 05/2017, Volume 9, Issue 8, pp. 731 - 748
Parkinson's | imidazoles | PDE10 inhibitors | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Cell Survival - drug effects | Phosphoric Diester Hydrolases - metabolism | Humans | Imidazoles - chemistry | Models, Molecular | Phosphodiesterase Inhibitors - pharmacology | Imidazoles - pharmacology | Parkinson Disease - drug therapy | Cell Line, Tumor | Phosphodiesterase Inhibitors - chemical synthesis | Molecular Structure | Parkinson Disease - metabolism | Imidazoles - chemical synthesis | Phosphodiesterase Inhibitors - chemistry
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9. Full Text Candida tropicalis bloodstream infection: Incidence, risk factors and outcome in a population-based surveillance
by Fernández-Ruiz, Mario and Puig-Asensio, Mireia and Guinea, Jesús and Almirante, Benito and Padilla, Belén and Almela, Manuel and Díaz-Martín, Ana and Rodríguez-Baño, Jesús and Cuenca-Estrella, Manuel and Aguado, José María and REIPI and CANDIPOP Project and GEIH-GEMICOMED (SEIMC) and GEIH-GEMICOMED SEIMC
The Journal of infection, ISSN 0163-4453, 2015, Volume 71, Issue 3, pp. 385 - 394
Infectious Disease | Treatment | Candida tropicalis bloodstream infection | Epidemiology | Outcome | Minimum inhibitory concentration | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Prospective Studies | Age Factors | Voriconazole - pharmacology | Humans | Middle Aged | Male | Candidemia - mortality | Candida tropicalis - drug effects | Fluconazole - therapeutic use | Antifungal Agents - therapeutic use | Incidence | Microbial Sensitivity Tests | Time Factors | Aged, 80 and over | Adult | Female | Drug Resistance, Fungal | Leukemia - epidemiology | Antifungal Agents - pharmacology | Candidemia - microbiology | Comorbidity | Risk Factors | Voriconazole - therapeutic use | Central Venous Catheters - adverse effects | Candidemia - epidemiology | Spain - epidemiology | Aged | Population Surveillance | Cross infection | Nosocomial infections | Health aspects | Emergency medicine | Risk factors | Index Medicus
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