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The New England Journal of Medicine, ISSN 0028-4793, 07/2012, Volume 367, Issue 1, pp. 11 - 19
Journal Article
British Journal of Haematology, ISSN 0007-1048, 02/2012, Volume 156, Issue 3, pp. 295 - 302
Monogenic hereditary diseases, such as haemophilia A and B, are ideal targets for gene therapeutic approaches. While these diseases can be treated with protein... 
haemophilia | factor VIII (FVIII) | factor IX (FIX) | gene therapy | immune tolerance | Haemophilia | Factor IX (FIX) | Factor VIII (FVIII) | Gene therapy | Immune tolerance | ANTIGEN-SPECIFIC EFFECTOR | A MICE | IMMUNOLOGICAL-TOLERANCE | HUMAN-FACTOR-VIII | HEMATOPOIETIC STEM-CELLS | FACTOR-IX | REGULATORY T-CELLS | TRANSGENE PRODUCT | NEPHROTIC SYNDROME | HEMATOLOGY | IMMUNE TOLERANCE INDUCTION | Hemophilia B - therapy | Recombinant Fusion Proteins - immunology | Dependovirus - genetics | Factor IX - antagonists & inhibitors | Factor VIII - immunology | Isoantibodies - biosynthesis | Factor IX - therapeutic use | Humans | Recombinant Fusion Proteins - therapeutic use | Genetic Vectors - adverse effects | Male | Genetic Vectors - therapeutic use | T-Lymphocytes, Regulatory - immunology | Recombinant Fusion Proteins - antagonists & inhibitors | Retroviridae - genetics | Factor VIII - antagonists & inhibitors | Female | Factor VIII - therapeutic use | Recombinant Fusion Proteins - biosynthesis | Gene Transfer Techniques | Factor IX - immunology | Genetic Vectors - immunology | Gene Expression Regulation | Genes, Synthetic | Factor VIII - genetics | Immune Tolerance | Cell Transplantation | Dependovirus - immunology | Factor IX - genetics | Hemophilia B - genetics | Hemophilia A - therapy | Forecasting | Genetic Vectors - genetics | Recombinant Fusion Proteins - genetics | Hemophilia A - genetics | Factor VIII - biosynthesis | Clinical Trials, Phase I as Topic | Factor IX - biosynthesis | Genetic Therapy - methods | Prevention | Anopheles | Care and treatment | Blood coagulation factor VIII | Genes | Hemophilia | Health aspects | Prothrombin complex concentrate | inhibitors | vectors | factor VIII (F8) | factor IX (F9)
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2012, Volume 366, Issue 3, pp. 280 - 281
To the Editor: Delyon et al. (Nov. 3 issue) 1 describe a patient with acquired hemophilia A after treatment with ipilimumab for melanoma. Ipilimumab is a... 
MEDICINE, GENERAL & INTERNAL | Melanoma - complications | Male | Humans | Antibodies, Monoclonal - adverse effects | Hemophilia A - chemically induced | Coagulation factors | Proteins | Hemophilia | Melanoma | Amino acid sequence | Coagulation factor VIII | Patients
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 23, pp. 4452 - 4453
Journal Article
American Journal of Medical Genetics Part A, ISSN 1552-4825, 09/2017, Volume 173, Issue 9, pp. 2359 - 2365
Patients with overgrowth and complex vascular malformation syndromes, including Proteus syndrome have an increased risk of thromboembolism. Proteus syndrome is... 
thrombosis | pulmonary embolism (PE) | deep vein thrombosis (DVT) | Proteus syndrome | DEEP-VEIN THROMBOSIS | VENOUS MALFORMATIONS | KLIPPEL-TRENAUNAY-SYNDROME | PULMONARY-EMBOLISM | GENETICS & HEREDITY | VASCULAR MALFORMATIONS | THROMBOEMBOLISM | COAGULATION ABNORMALITIES | D-DIMER | ACTIVATING MUTATIONS | CLOVES SYNDROME | Lupus Coagulation Inhibitor - blood | Humans | Middle Aged | Child, Preschool | Male | Antithrombin III Deficiency - genetics | Antithrombin III Deficiency - blood | Proteus Syndrome - blood | Proto-Oncogene Proteins c-akt - genetics | Adult | Female | Thrombosis - blood | Child | Fibrin Fibrinogen Degradation Products - genetics | Protein C Deficiency - blood | Pulmonary Embolism - genetics | Thrombosis - physiopathology | Risk Factors | Pulmonary Embolism - blood | Endothelium, Vascular - metabolism | Proto-Oncogene Proteins c-akt - blood | Adolescent | Endothelium, Vascular - pathology | Proteus Syndrome - physiopathology | Thrombosis - genetics | Aged | Factor V - genetics | Proteus Syndrome - genetics | Protein S Deficiency - blood | Pulmonary Embolism - physiopathology | Thromboembolism | Development and progression | Care and treatment | AKT1 protein | Heterozygotes | Protein C | Thrombosis | Antithrombin | Embolism | Risk factors | Endothelium | Coagulation factors | Factor V | Surgery | Skin | Health risk assessment | Deep vein thrombosis (DVT) | Pulmonary embolism (PE)
Journal Article
Journal Article
British Journal of Haematology, ISSN 0007-1048, 02/2012, Volume 156, Issue 3, pp. 295 - 302
Journal Article
by Sadd, Ben M and Barribeau, Seth M and Bloch, Guy and de Graaf, Dirk C and Dearden, Peter and Elsik, Christine G and Gadau, Jürgen and Grimmelikhuijzen, Cornelis J.P and Hasselmann, Martin and Lozier, Jeffrey D and Robertson, Hugh M and Smagghe, Guy and Stolle, Eckart and Van Vaerenbergh, Matthias and Waterhouse, Robert M and Bornberg-Bauer, Erich and Klasberg, Steffen and Bennett, Anna K and Câmara, Francisco and Guigó, Roderic and Hoff, Katharina and Mariotti, Marco and Munoz-Torres, Monica and Murphy, Terence and Santesmasses, Didac and Amdam, Gro V and Beckers, Matthew and Beye, Martin and Biewer, Matthias and Bitondi, Márcia M.G and Blaxter, Mark L and Bourke, Andrew F.G and Brown, Mark J.F and Buechel, Severine D and Cameron, Rossanah and Cappelle, Kaat and Carolan, James C and Christiaens, Olivier and Ciborowski, Kate L and Clarke, David F and Colgan, Thomas J and Collins, David H and Cridge, Andrew G and Dalmay, Tamas and Dreier, Stephanie and du Plessis, Louis and Duncan, Elizabeth and Erler, Silvio and Evans, Jay and Falcon, Tiago and Flores, Kevin and Freitas, Flávia C.P and Fuchikawa, Taro and Gempe, Tanja and Hartfelder, Klaus and Hauser, Frank and Helbing, Sophie and Humann, Fernanda C and Irvine, Frano and Jermiin, Lars S and Johnson, Claire E and Johnson, Reed M and Jones, Andrew K and Kadowaki, Tatsuhiko and Kidner, Jonathan H and Koch, Vasco and Köhler, Arian and Kraus, F. Bernhard and Lattorff, H. Michael G and Leask, Megan and Lockett, Gabrielle A and Mallon, Eamonn B and Antonio, David S. Marco and Marxer, Monika and Meeus, Ivan and Moritz, Robin F.A and Nair, Ajay and Näpflin, Kathrin and Nissen, Inga and Niu, Jinzhi and Nunes, Francis M.F and Oakeshott, John G and Osborne, Amy and Otte, Marianne and Pinheiro, Daniel G and Rossié, Nina and Rueppell, Olav and Santos, Carolina G and Schmid-Hempel, Regula and Schmitt, Björn D and Schulte, Christina and Simões, Zilá L.P and Soares, Michelle P.M and Swevers, Luc and Winnebeck, Eva C and Wolschin, Florian and Yu, Na and Zdobnov, Evgeny M and Aqrawi, Peshtewani K and Blankenburg, Kerstin P and ...
Genome Biology, ISSN 1474-7596, 04/2015, Volume 16, Issue 1, p. 76
Journal Article