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1868, 5,6,2,34 double leaves
Book
Science, ISSN 0036-8075, 7/2001, Volume 293, Issue 5528, pp. 306 - 311
Receptor tyrosine kinases and their ligands mediate cell-cell communication and interaction in many organ systems, but have not been known to act in this... 
T lymphocytes | Spleen | Receptors | Pain | Messenger RNA | B lymphocytes | Lymphocytes | Antibodies | Antigen presenting cells | Reports | Lymph nodes | ANTIBODIES | EXPRESSION ANALYSIS | LIGANDS | C-MER | AXL | CLONING | MULTIDISCIPLINARY SCIENCES | PROTEIN-S | SELECTION | GAS6 | Oncogene Proteins - genetics | Protein Biosynthesis | Immune System - physiology | Spleen - immunology | Dendritic Cells - immunology | Receptor Protein-Tyrosine Kinases - physiology | Homeostasis | Male | Lymphoid Tissue - growth & development | RNA, Messenger - metabolism | Oncogene Proteins - physiology | Lymphoid Tissue - immunology | Autoimmune Diseases - genetics | Lymphocytes - immunology | c-Mer Tyrosine Kinase | Female | Cell Differentiation | Proto-Oncogene Proteins | Protein S - biosynthesis | Autoimmune Diseases - pathology | Macrophages - immunology | Protein S - genetics | Lymphocyte Activation | Intercellular Signaling Peptides and Proteins | Autoimmune Diseases - immunology | Cell Transplantation | Lymphocytes - cytology | Spleen - cytology | Neural Cell Adhesion Molecules - genetics | Antigen-Presenting Cells - immunology | Proteins - genetics | Macrophages - metabolism | Animals | Receptor Protein-Tyrosine Kinases - genetics | Mice | Mutation | Neural Cell Adhesion Molecules - physiology | Research | B cells | T cells | Immune system | Proteins | Genetics | Rodents | Cells
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e115140
Tyro3, Axl and Mertk (TAM) receptor tyrosine kinases play multiple functional roles by either providing intrinsic trophic support for cell growth or regulating... 
NERVOUS-SYSTEM | AXL | MULTIDISCIPLINARY SCIENCES | APOPTOTIC CELLS | ADULT HIPPOCAMPAL NEUROGENESIS | TYROSINE KINASES | TRK RECEPTORS | NEUROTROPHINS | MER | NGF | TYRO-3 FAMILY | Cell Proliferation | Receptor Protein-Tyrosine Kinases - biosynthesis | Apoptosis - genetics | Recombinant Proteins | Proto-Oncogene Proteins - biosynthesis | Neurogenesis - genetics | Receptor, trkA - biosynthesis | c-Mer Tyrosine Kinase | Brain-Derived Neurotrophic Factor - biosynthesis | Proto-Oncogene Proteins - metabolism | Receptors, Nerve Growth Factor - biosynthesis | Cell Survival | Receptor, trkB - biosynthesis | Cells, Cultured | Proto-Oncogene Proteins - genetics | Hippocampus - cytology | Nerve Growth Factors - biosynthesis | Receptor Protein-Tyrosine Kinases - metabolism | Mice, Knockout | Hippocampus - metabolism | Animals | Receptor Protein-Tyrosine Kinases - genetics | Receptor, trkC - biosynthesis | Mice | Neural Stem Cells - metabolism | Brain | Nerve growth factor | Tubulins | Cell differentiation | Neurons | Stem cells | Cell proliferation | Neurosciences | Neurobiology | Central nervous system | Nervous system | Kinases | Neurogenesis | Neuronal-glial interactions | Axl protein | Proteins | Signal transduction | Receptors | Cell activation | Cell growth | Tubulin | Rodents | TrkA protein | Protein-tyrosine kinase receptors | TrkA receptors | Neurotrophins | Growth factors | Tyrosine | Cell survival | Immune response | Axonogenesis | Inflammation | Gene expression | Survival | Medicine | Brain-derived neurotrophic factor | Neural stem cells | TrkB receptors | Differentiation | Hippocampus | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e64812
The Tyro3, Axl and Mertk (TAM) triply knockout (TKO) mice exhibit systemic autoimmune diseases, with characteristics of increased proinflammatory cytokine... 
INTERCELLULAR-ADHESION MOLECULE-1 | RECEPTOR TYROSINE KINASES | MRL-LPR MICE | MULTIPLE-SCLEROSIS | TYRO-3 FAMILY RECEPTORS | MULTIDISCIPLINARY SCIENCES | LUPUS-PRONE MICE | NECROSIS-FACTOR-ALPHA | CENTRAL-NERVOUS-SYSTEM | BLOOD-BRAIN | HUMAN ENDOTHELIAL-CELLS | Autoantibodies - blood | Tumor Necrosis Factor-alpha - blood | Microvessels - metabolism | Capillary Permeability - immunology | Mice, 129 Strain | Microvessels - immunology | Brain Damage, Chronic - genetics | Gene Knockdown Techniques | Autoimmune Diseases - genetics | Dentate Gyrus - immunology | Dentate Gyrus - blood supply | c-Mer Tyrosine Kinase | Inflammation Mediators - metabolism | Neurons - physiology | Female | Inclusion Bodies - metabolism | Autoimmune Diseases - pathology | Brain Damage, Chronic - pathology | Ubiquitinated Proteins - metabolism | Cytokines - metabolism | Endothelial Cells - metabolism | Mice, Inbred C57BL | Autoimmune Diseases - immunology | Cells, Cultured | Proto-Oncogene Proteins - genetics | Blood-Brain Barrier - metabolism | Mice, Knockout | CA3 Region, Hippocampal - blood supply | Endothelial Cells - immunology | Animals | CA3 Region, Hippocampal - immunology | Receptor Protein-Tyrosine Kinases - genetics | Lipopolysaccharides - pharmacology | Brain Damage, Chronic - immunology | T-Lymphocytes - immunology | Mice | CA3 Region, Hippocampal - pathology | Dentate Gyrus - pathology | Apoptosis | Ubiquitin | Dextran | Autoimmunity | Brain | Autoantibodies | Cytokines | Neurons | Cell death | Biochemistry | Permeability | T cells | Neurosciences | Multiple sclerosis | Disease | Laboratories | Cognitive ability | Fluorescence | Smooth muscle | Nervous system | Lymphocytes T | Kinases | Blood | Axl protein | Cell adhesion & migration | Fibers | Proteins | Blood-brain barrier | Neurodegeneration | Lymphocytes | Rodents | Animal tissues | Protein-tyrosine kinase receptors | Tumor necrosis factor-TNF | Lupus | Antigens | Immunoglobulins | Mortality | Blood vessels | Inflammation | Tumor necrosis factor-α | Ligands | Brain damage | Infiltration | Autoimmune diseases | Mossy fibers | Brain injury | Hippocampus | Animal cognition
Journal Article
by Xu, Q and Lu, Z and Wang, XG and Zhu, QX and Wu, HR
JOURNAL OF INVESTIGATIVE MEDICINE, ISSN 1081-5589, 08/2019, Volume 67, Issue 6, pp. 1009 - 1017
Secreted frizzled-related protein 5 (SFRP5) has been reported to be downregulated in prostate cancer. However, its biological role in this malignancy has not... 
TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | ANTAGONIST | cell proliferation | SURVIVIN | PROLIFERATION | MEDICINE, GENERAL & INTERNAL | SFRP5 | GENES | cancer | CELL-CYCLE | EXPRESSION | PROGRESSION | BLOOD
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2010, Volume 392, Issue 4, pp. 593 - 598
14-3-3σ (also called stratifin) is specifically expressed in the stratified squamous epithelium and its function was recently shown to be linked to epidermal... 
Corneal epithelial | Proliferation | 14-3-3σ | Differentiation | Notch | differentiation | proliferation | corneal epithelial
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2015, Volume 10, Issue 1, p. e0117787
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e87530
Journal Article
Development, ISSN 0950-1991, 1997, Volume 124, Issue 20, pp. 4121 - 4131
Journal Article
STEM CELLS, ISSN 1066-5099, 07/2013, Volume 31, Issue 7, pp. 1350 - 1362
In this study, we demonstrate that sphere formation triggers immortalization and stable reprogramming of mouse fibroblasts. Cell contact signaling in spheres... 
Hypoxia | Adult stem cells | Reprogramming | Differentiation | PROLIFERATION | CANCER STEM-CELLS | DNA DEMETHYLATION | PLURIPOTENT | CELL & TISSUE ENGINEERING | CELL BIOLOGY | OXYGEN | GENE | ONCOLOGY | PATHWAY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | COMPONENT | GROWTH-FACTOR | HEMATOLOGY | EXPRESSION | Cell Hypoxia - physiology | Epithelial-Mesenchymal Transition - physiology | Homeodomain Proteins - metabolism | Multipotent Stem Cells - metabolism | Octamer Transcription Factor-3 - biosynthesis | Transcriptome | Stem Cells - cytology | Epithelial-Mesenchymal Transition - genetics | Stem Cells - metabolism | Gene Knockdown Techniques | DNA (Cytosine-5-)-Methyltransferases - metabolism | Octamer Transcription Factor-3 - genetics | Cell Differentiation - genetics | DNA Methylation | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Kruppel-Like Transcription Factors - metabolism | Kruppel-Like Transcription Factors - deficiency | Multipotent Stem Cells - physiology | Cell Differentiation - physiology | Fibroblasts - metabolism | Promoter Regions, Genetic | DNA (Cytosine-5-)-Methyltransferase 1 | Cytidine Deaminase - genetics | Cells, Cultured | Homeodomain Proteins - genetics | Animals | Multipotent Stem Cells - cytology | Cytidine Deaminase - metabolism | Octamer Transcription Factor-3 - metabolism | Stem Cells - physiology | Fibroblasts - cytology | Mice | Cell Hypoxia - genetics | Kruppel-Like Transcription Factors - genetics | Zinc Finger E-box-Binding Homeobox 1 | Methyltransferases | Gene expression | Analysis | Stem cells | Proteins | Spheres | Kinases
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2005, Volume 102, Issue 44, pp. 15977 - 15982
Repeated-epilation (Er) mutation in the mouse is inherited as an autosomal and semidominant mutation. Major defects in heterozygous adults and homozygous... 
Proteins | Biological Sciences | Epidermal cells | Genes | Genomics | Keratinocytes | Epidermis | Skin | Mice | Genetic mutation | Embryos | Genetics | Epidermal development | IKK1 | Stratifin | stratifin | epidermal development | genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, pp. e0121185 - e0121185
The inhibition of NF-kappa B by genetic deletion or pharmacological inhibition of IKK2 significantly reduces laser-induced choroid neovascularization (CNV). To... 
CELLS | MICROSPHERES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | MACULAR DEGENERATION | RETINOPATHY | MICE | MODEL | NF-KAPPA-B | RANIBIZUMAB | BETA | Lactic Acid - chemistry | Macrophages - pathology | Mice, Inbred C57BL | Drug Carriers - administration & dosage | Male | Thiophenes - administration & dosage | Macrophages - cytology | Drug Carriers - chemistry | Protein Kinase Inhibitors - administration & dosage | Protein Kinase Inhibitors - chemistry | Animals | Choroidal Neovascularization - drug therapy | Choroidal Neovascularization - pathology | I-kappa B Kinase - antagonists & inhibitors | Polyglycolic Acid - chemistry | Amides - chemistry | Female | Macrophages - drug effects | Mice | Thiophenes - chemistry | Amides - administration & dosage | Lactic Acid - administration & dosage | Polyglycolic Acid - administration & dosage | Disease Models, Animal | Macular degeneration | Employee recruitment | Neovascularization | Macrophages | Fluorescein | Diabetic retinopathy | Biodegradability | IKK2 protein | Retina | Microparticles | Vascularization | Recruitment | Angiogenesis | Lasers | Biocompatibility | Eye (anatomy) | Inhibition | Polymers | Vascular endothelial growth factor | Medical research | NF-κB protein | Solvents | Stability | Molecular chains | Injury prevention | Inhibitors | Infiltration | Monocyte chemoattractant protein 1 | Drug delivery systems | Toxicity | Medical services | Staining | Kinases | Experiments | Optokinetic response | Polylactide-co-glycolide | Nanoparticles | Clonal deletion | Eye injuries | Rodents | Deletion | Attenuation | Age | Biodegradation | Departments | Inflammation | Histology | Pharmacology | Breast cancer | Evaporation | Medicine | Eye diseases | In vivo methods and tests | Laboratory animals | Index Medicus
Journal Article