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1. Full Text Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance
by Hu, Yunwen, MD and Lu, Shuihua, MD and Song, Zhigang, MS and Wang, Wei, PhD and Hao, Pei, PhD and Li, Jianhua, PhD and Zhang, Xiaonan, PhD and Yen, Hui-Ling, PhD and Shi, Bisheng, MS and Li, Tao, MD and Guan, Wencai, BA and Xu, Lei, BA and Liu, Yi, BA and Wang, Sen, PhD and Zhang, Xiaoling, BA and Tian, Di, MS and Zhu, Zhaoqin, PhD and He, Jing, MS and Huang, Kai, PhD and Chen, Huijie, PhD and Zheng, Lulu, PhD and Li, Xuan, PhD and Ping, Jie, PhD and Kang, Bin, PhD and Xi, Xiuhong, MD and Zha, Lijun and Li, Yixue, PhD and Zhang, Zhiyong, MD and Peiris, Malik, Dr and Yuan, Zhenghong, Dr
Lancet, The, ISSN 0140-6736, 2013, Volume 381, Issue 9885, pp. 2273 - 2279
Summary Background On March 30, a novel influenza A subtype H7N9 virus (A/H7N9) was detected in patients with severe respiratory disease in eastern China.... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | MUTATIONS | Influenza A virus - physiology | Antiviral Agents - therapeutic use | Oseltamivir - therapeutic use | Humans | Influenza A virus - genetics | Middle Aged | Drug Resistance, Viral | Molecular Sequence Data | Influenza, Human - epidemiology | Male | Virus Shedding | China - epidemiology | RNA, Viral - genetics | Base Sequence | Aged, 80 and over | Cyclopentanes - therapeutic use | Female | Influenza, Human - virology | Aged | Influenza, Human - drug therapy | Influenza A virus - drug effects | Guanidines - therapeutic use | Antiviral agents | Medical colleges | Biosafety | Influenza | Patient outcomes | Pneumonia | Respiratory distress syndrome | Microbiology | Genes | Viruses | Ventilation | Chronic obstructive pulmonary disease | Genomes | Mutation | Patients | Binding sites
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2. Full Text Latent tuberculosis infection in rural China: baseline results of a population-based, multicentre, prospective cohort study
by Gao, Lei, PhD and Lu, Wei, PhD and Bai, Liqiong, PhD and Wang, Xinhua, PhD and Xu, Jinsheng, MD and Catanzaro, Antonino, PhD and Cárdenas, Vicky, PhD and Li, Xiangwei, MD and Yang, Yu, PhD and Du, Jiang, MD and Sui, Hongtao, MPH and Xia, Yinyin, PhD and Li, Mufei, BS and Feng, Boxuan, BS and Li, Zhen, BS and Xin, Henan, BS and Zhao, Rong, PhD and Liu, Jianmin, MD and Pan, Shouguo, MD and Shen, Fei, MPH and He, Jian, PhD and Yang, Shumin, MPH and Si, Hongyan, MPH and Wang, Yi, MPH and Xu, Zuhui, MPH and Tan, Yunhong, MPH and Chen, Tianzhu, MD and Xu, Weiguo, MD and Peng, Hong, MD and Wang, Zhijian, MPH and Zhu, Tao, MPH and Zhou, Feng, PhD and Liu, Haiying, PhD and Zhao, Yanlin, Prof and Cheng, Shiming, Prof and Jin, Qi, Prof and LATENTTB-NSTM Study Team and LATENTTB-NSTM study team
Lancet Infectious Diseases, The, ISSN 1473-3099, 2015, Volume 15, Issue 3, pp. 310 - 319
Summary Background Prophylactic treatment of individuals with latent Mycobacterium tuberculosis infection is an essential component of tuberculosis control in... 
Infectious Disease | UNITED-STATES | DIAGNOSIS | INFECTIOUS DISEASES | METAANALYSIS | SKIN-TEST | SMOKE | PREVALENCE | GAMMA RELEASE ASSAYS | Prevalence | Prospective Studies | Interferon-gamma Release Tests | Humans | Middle Aged | Latent Tuberculosis - epidemiology | Child, Preschool | Male | China - epidemiology | Tuberculin Test | Young Adult | Rural Population | Adolescent | Aged, 80 and over | Adult | Female | Aged | Child | Cohort Studies | Prevention | Tuberculosis | Health aspects | Analysis | Prevalence studies (Epidemiology) | Studies | Disease prevention | Disease | Family income | Laboratories | Households | Rural areas | Skin | Infections | Multivariate analysis | Epidemiology
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3. Full Text Biotinylated liposomes as potential carriers for the oral delivery of insulin
by Zhang, Xingwang, PhD and Qi, Jianping, PhD and Lu, Yi, PhD and He, Wei, PhD and Li, Xiaoyang, MSc and Wu, Wei, PhD
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2014, Volume 10, Issue 1, pp. 167 - 176
Abstract This study aimed to explore biotinylated liposomes (BLPs) as novel carriers to enhance the oral delivery of insulin. Biotinylation was achieved by... 
Internal Medicine | Biotin | Liposomes | Receptor-mediated endocytosis | Insulin | Oral delivery | MEDICINE, RESEARCH & EXPERIMENTAL | SITE | SYSTEMS PREPARATION | VEHICLE | PROTEIN | PERORAL DELIVERY | NANOSCIENCE & NANOTECHNOLOGY | BIOAVAILABILITY | NANOPARTICLES | IN-VITRO | GLUCAGON-LIKE PEPTIDE-1 | DRUGS | Diabetes Mellitus - pathology | Diabetes Mellitus, Experimental - drug therapy | Administration, Oral | Liposomes - administration & dosage | Humans | Diabetes Mellitus - drug therapy | Rats | Blood Glucose | Insulin - administration & dosage | Drug Carriers | Drug Delivery Systems | Liposomes - chemistry | Animals | Insulin - chemistry | Membrane lipids | Blood lipids
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4. Full Text Consensus guidelines for implementing pencil beam scanning proton therapy for thoracic malignancies on behalf of PTCOG thoracic and lymphoma subcommittee
by Chang, Joe Y., MD, PhD and Zhang, Xiaodong, PhD and Knopf, Antje, PhD and Li, Heng, PhD and Mori, Shinichiro, PhD and Dong, Lei, PhD and Lu, Hsiao-Ming, PhD and Liu, Wei, PhD and Badiyan, Shahed N., MD and Both, Stephen, PhD and Meijers, Arturs and Lin, Liyong, PhD and Flampouri, Stella, PhD and Li, Zuofeng, DSc and Umegaki, Kikuo, PhD and Simone, Charles B., MD and Zhu, Xiaorong R., PhD
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2017, Volume 99, Issue 1, pp. 41 - 50
Abstract Pencil beam scanning (PBS) proton therapy (PT), particularly intensity-modulated proton therapy, represents the latest advanced proton therapy... 
Radiology | Hematology, Oncology and Palliative Medicine | CELL LUNG-CANCER | ONCOLOGY | MOVING TARGETS | PARTICLE THERAPY | POLYMER GEL DOSIMETER | RESPIRATORY MOTION | TUMOR MOTION | MOTION MITIGATION | TREATMENT UNCERTAINTIES | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ROBUST OPTIMIZATION | RADIATION-THERAPY | Uncertainty | Movement | Humans | Lung | Radiotherapy, Intensity-Modulated - methods | Thoracic Neoplasms - pathology | Breath Holding | Organs at Risk | Tumor Burden | Thoracic Neoplasms - diagnostic imaging | Four-Dimensional Computed Tomography | Esophagus | Thoracic Neoplasms - radiotherapy | Quality Improvement | Simulation Training - methods | Proton Therapy - methods | Respiration | Practice Guidelines as Topic | Medical research | Medical colleges | CT imaging | Care and treatment | Radiation | Medicine, Experimental | Lymphomas | Radiotherapy | Cancer | Index Medicus | LYMPHOMAS | PLATINUM | RADIOLOGY AND NUCLEAR MEDICINE | PROTON BEAMS | RADIATION DOSES | RADIOTHERAPY | COMPUTERIZED TOMOGRAPHY
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5. Full Text HIV prevalence in China: integration of surveillance data and a systematic review
by Zhang, Lei, Dr and Chow, Eric P F, MPH and Jing, Jun, Prof and Zhuang, Xun, Prof and Li, Xiaoshan, BMed and He, Meiqi, BMed and Sun, Huamin, BMed and Li, Xiaoyan, BMed and Gorgens, Marelize, MPH and Wilson, David, PhD and Wang, Lan, PhD and Guo, Wei, PhD and Li, Dongming, PhD and Cui, Yan, MD and Wang, Lu, PhD and Wang, Ning, Prof and Wu, Zunyou, Prof and Wilson, David P, PhD
Lancet Infectious Diseases, The, ISSN 1473-3099, 2013, Volume 13, Issue 11, pp. 955 - 963
Summary Background Asian HIV epidemics are concentrated among particular behavioural groups, but large variations exist in epidemic types, timing, and... 
Infectious Disease | DRUG-USERS | INFECTIOUS DISEASES | MAINTENANCE TREATMENT CLINICS | METAANALYSIS | SYPHILIS | SEX | MEN | INFECTION | HARM REDUCTION | EFFECTIVE RESPONSE | HIV/AIDS EPIDEMIC | Epidemics | Prevalence | HIV Infections - epidemiology | HIV Infections - virology | Humans | Male | HIV - isolation & purification | China - epidemiology | Substance-Related Disorders - epidemiology | Female | HIV Infections - transmission | Homosexuality, Male - statistics & numerical data | Sentinel Surveillance | Sex Workers - statistics & numerical data | Substance-Related Disorders - virology | HIV (Viruses) | Public health | Prevalence studies (Epidemiology)
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6. Full Text Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003–11): a national observational cohort study
by Jia, Zhongwei, PhD and Mao, Yurong, PhD and Zhang, Fujie, PhD and Ruan, Yuhua, Prof and Ma, Ye, PhD and Li, Jian, PhD and Guo, Wei, PhD and Liu, Enwu, PhD and Dou, Zhihui, MS and Zhao, Yan, MD and Wang, Lu, PhD and Li, Qianqian and Xie, Peiyan, BS and Tang, Houlin, MS and Han, Jing, MS and Jin, Xia, MS and Xu, Juan, PhD and Xiong, Ran, MS and Zhao, Decai, MS and Li, Ping and Wang, Xia, MPH and Wang, Liyan, PhD and Qing, Qianqian, MD and Ding, Zhengwei, BS and Chen, Ray Y, MD and Liu, Zhongfu, Prof and Shao, Yiming, Prof
Lancet, The, ISSN 0140-6736, 2013, Volume 382, Issue 9899, pp. 1195 - 1203
Summary Background On the basis of the results of the randomised clinical trial HPTN 052 and observational studies, WHO has recommended that antiretroviral... 
Internal Medicine | VIRAL LOAD | MORTALITY | MEDICINE, GENERAL & INTERNAL | INFECTED INDIVIDUALS | SEROCONVERSION | METAANALYSIS | HETEROSEXUAL TRANSMISSION | DRUG-RESISTANCE | HUMAN-IMMUNODEFICIENCY-VIRUS | SEXUAL TRANSMISSION | DISCORDANT COUPLES | HIV Infections - prevention & control | Heterosexuality - statistics & numerical data | HIV Seronegativity - drug effects | HIV Infections - epidemiology | Humans | Middle Aged | Male | China - epidemiology | Socioeconomic Factors | Feasibility Studies | Incidence | Young Adult | Adolescent | Adult | Anti-HIV Agents - therapeutic use | Female | Aged | Retrospective Studies | Sexual Partners | Prevention | Antiviral agents | Complications and side effects | Dosage and administration | Drug therapy | HIV infection | Antiretroviral drugs | Disease transmission | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV
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7. Full Text Environment-responsive aza-BODIPY dyes quenching in water as potential probes to visualize the in vivo fate of lipid-based nanocarriers
by Hu, Xiongwei, PhD and Zhang, Jian, BSc and Yu, Zhou, BSc and Xie, Yunchang, BSc and He, Haisheng, BSc and Qi, Jianping, PhD and Dong, Xiaochun, PhD and Lu, Yi, PhD and Zhao, Weili, PhD and Wu, Wei, PhD
Nanomedicine: Nanotechnology, Biology, and Medicine, ISSN 1549-9634, 2015, Volume 11, Issue 8, pp. 1939 - 1948
Abstract Environment-responsive near-infrared (NIR) aza-BODIPY dyes capable of fluorescence quenching in water were explored to visualize the in vivo fate of... 
Internal Medicine | In vivo fate | BODIPY | Drug delivery | Lipid-based nanocarriers | Water-quenching | VITRO | MEDICINE, RESEARCH & EXPERIMENTAL | HIGHLY FLUORESCENT | NANOSCIENCE & NANOTECHNOLOGY | IMPROVED ORAL BIOAVAILABILITY | CARRIERS | DELIVERY | SOLUBLE DRUG | NANOPARTICLES | DIGESTION | FORMULATIONS | ABSORPTION | Boron Compounds - chemistry | Fluorescent Dyes - chemistry | Optical Imaging | Nanoparticles - analysis | Animals | Lipids - pharmacokinetics | Mice, Nude | Water - chemistry | Fluorescence | Drug Carriers - analysis | Drug Carriers - pharmacokinetics | Lipids - analysis | Investigations
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8. Full Text Spatial-Temporal [18 F]FDG-PET Features for Predicting Pathologic Response of Esophageal Cancer to Neoadjuvant Chemoradiation Therapy
by Tan, Shan, PhD and Kligerman, Seth, MD and Chen, Wengen, MD, PhD and Lu, Minh, MD and Kim, Grace, MD and Feigenberg, Steven, MD and D'Souza, Warren D., PhD and Suntharalingam, Mohan, MD and Lu, Wei, PhD
International Journal of Radiation Oncology, Biology, Physics, ISSN 0360-3016, 2013, Volume 85, Issue 5, pp. 1375 - 1382
Purpose To extract and study comprehensive spatial-temporal18 F-labeled fluorodeoxyglucose ([18 F]FDG) positron emission tomography (PET) features for the... 
Radiology | Hematology, Oncology and Palliative Medicine | SURGERY | CHEMORADIOTHERAPY | POSITRON-EMISSION-TOMOGRAPHY | ONCOLOGY | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | FDG PET | Fluorodeoxyglucose F18 - pharmacokinetics | Adenocarcinoma - pathology | Area Under Curve | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Tomography, X-Ray Computed | Carcinoma, Squamous Cell - diagnostic imaging | Positron-Emission Tomography | Cisplatin - administration & dosage | Esophageal Neoplasms - pathology | Adenocarcinoma - metabolism | Fluorouracil - administration & dosage | Esophageal Neoplasms - metabolism | Multimodal Imaging - methods | Female | Spatio-Temporal Analysis | Retrospective Studies | Esophageal Neoplasms - therapy | Radiopharmaceuticals - pharmacokinetics | Carcinoma, Squamous Cell - therapy | Chemoradiotherapy, Adjuvant - methods | Adenocarcinoma - therapy | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoadjuvant Therapy - methods | Adenocarcinoma - diagnostic imaging | Esophageal Neoplasms - diagnostic imaging | PET imaging | Nuclear radiation | Health aspects | Esophageal cancer | Adjuvant treatment | Cancer | IMAGE PROCESSING | THERAPY | NEOPLASMS | ESOPHAGUS | POSITRON COMPUTED TOMOGRAPHY | FLUORODEOXYGLUCOSE | RADIOLOGY AND NUCLEAR MEDICINE | COMPUTERIZED TOMOGRAPHY | FLUORINE 18
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9. Full Text A Meta-Analysis of Miniaturized Versus Conventional Extracorporeal Circulation in Valve Surgery
by Wang, Chuangshi, MM and Hua, Kun, PhD and Yin, Lu, PhD and Wang, Yang, MSc and Li, Wei, PhD
Annals of Thoracic Surgery, ISSN 0003-4975, 2016, Volume 102, Issue 6, pp. 2099 - 2108
The effects of miniaturized extracorporeal circulation in patients operated on for heart valve surgery are still inconsistent. We performed a meta-analysis of... 
Surgery | Cardiothoracic Surgery | SURGERY | CORONARY SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | AORTIC-VALVE | PUMP | REPLACEMENT | MINIMIZED CARDIOPULMONARY BYPASS | RESPIRATORY SYSTEM | CARDIAC-SURGERY | SYSTEMIC INFLAMMATORY RESPONSE | PERFUSION | MICROEMBOLI | CIRCUIT | Treatment Outcome | Cardiac Surgical Procedures | Heart Valve Diseases - surgery | Humans | Extracorporeal Circulation - instrumentation | Health aspects | Analysis | Cardiac patients
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10. Full Text Association of CASP7 Polymorphisms and Survival of Patients With Non-small Cell Lung Cancer With Platinum-Based Chemotherapy Treatment
by Qian, Ji, PhD and Gu, Shaohua, PhD and Wu, Qihan, PhD and Zhao, Xueying, PhD and Wu, Wenting, PhD and Gao, Zhiqiang, PhD and Zhang, Wei, PhD and Tan, Xiaoming, PhD and Wang, Haijian, PhD and Wang, Jiucun, PhD and Fan, Weiwei, PhD and Chen, Hongyan, PhD and Han, Baohui, PhD and Lu, Daru, PhD and Wei, Qingyi, PhD and Jin, Li, PhD
Chest, ISSN 0012-3692, 2012, Volume 142, Issue 3, pp. 680 - 689
Background CASP7 plays a crucial role in cancer development and chemotherapy efficacy. We, therefore, explored whether single nucleotide polymorphisms (SNPs)... 
Pulmonary/Respiratory | RHEUMATOID-ARTHRITIS | APOPTOSIS | CISPLATIN | RESPIRATORY SYSTEM | RESISTANCE | RISK | SEVERE TOXICITY | CLEAVAGE | CASPASE-7 GENE | EXPRESSION | CHINESE POPULATION | CRITICAL CARE MEDICINE | Lung Neoplasms - drug therapy | Prognosis | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Aged, 80 and over | Adult | Female | Retrospective Studies | Lung Neoplasms - genetics | Pharmacogenetics | Platinum - therapeutic use | Carcinoma, Non-Small-Cell Lung - genetics | Caspase 7 - genetics | Drug Therapy | Kaplan-Meier Estimate | Genotype | Survival Rate | Treatment Outcome | Carcinoma, Non-Small-Cell Lung - mortality | Regression Analysis | Polymorphism, Single Nucleotide - genetics | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Care and treatment | Platinum compounds | Patient outcomes | Physiological aspects | Genetic aspects | Dosage and administration | Research | Lung cancer, Non-small cell | Aspartic proteinases
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11. Full Text Attitudes to personalised versus standardised practice in traditional Chinese medicine: a national cross-sectional survey of practitioners in China
by Liu, Mengyu, Prof and Zhang, Chi, PhD and Zha, Qinglin, Prof and Yang, Wei, PhD and Yuwen, Ya, PhD and Zhong, Linda, MD and Bian, Zhaoxiang, Prof and Han, Xuejie, Prof and Lu, Aiping, Dr Prof
Lancet, The, ISSN 0140-6736, 2016, Volume 388, pp. S59 - S59
Abstract Background Critics argue that traditional Chinese medicine should focus on a personalised patient experience, and that standardised practices risk... 
Internal Medicine | Surveys | Medicine, Chinese
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