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Glia, ISSN 0894-1491, 09/2014, Volume 62, Issue 9, pp. 1486 - 1501
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, pp. e49635 - e49635
Journal Article
Journal of Physiology, ISSN 0022-3751, 05/2012, Volume 590, Issue 10, pp. 2285 - 2304
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2017, Volume 141, Issue 3, pp. 436 - 448
Journal Article
Frontiers in Cellular Neuroscience, ISSN 1662-5102, 08/2017, Volume 11, pp. 227 - 227
Inflammatory responses play a key role in many neural pathologies, with localized signaling from the non-immune cells making critical contributions. The NLRP3... 
Glaucoma | NFκB | Pannexin | Astrocytes | ATP release | NLRP3 | Caspase 1 | IL-1β | EXTRACELLULAR ATP | OPTIC-NERVE HEAD | glaucoma | caspase 1 | IL-1 beta | NEUROSCIENCES | RETINAL GANGLION-CELLS | PANNEXIN HEMICHANNELS | TRAUMATIC BRAIN-INJURY | ACUTE GLAUCOMA | P2X RECEPTOR | astrocytes | pannexin | NF-KAPPA-B | SUSTAINED ELEVATION | UP-REGULATION | NF kappa B | Cornea | Optic nerve | Cytokines | Retina | Inflammation | Pressure | Trauma | Ischemia | Apyrase | Mechanical stimuli | Laboratory animals
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 5726 - 14
Cross-reactions between innate immunity, lysosomal function, and purinergic pathways may link signaling systems in cellular pathologies. We found activation of... 
EXTRACELLULAR ATP | CLEARANCE | ACTIVATION | EXOCYTOSIS | RAT | CALCIUM HOMEOSTASIS | CULTURED HUMAN | MULTIDISCIPLINARY SCIENCES | RPE CELLS | NERVE HEAD ASTROCYTES | RECEPTORS | Starvation | Calcium | Phenylalanine | Astrocytes | Epithelial cells | Chloroquine | Lysosomes | Retina | Innate immunity | siRNA | Poly (I:C) | Rapamycin | Phosphatase | TLR3 protein | Signal transduction | Acids | Toll-like receptors | Apyrase | Acid phosphatase
Journal Article
Journal of neurochemistry, ISSN 0022-3042, 5/2017, Volume 141, Issue 3, pp. 436 - 448
Upregulation of IL-6 by mechanical strain involves pannexin-mediated ATP release and autostimulation of P2X7 receptors. Increased expression of IL-6 mRNA and... 
stretch | Cytokines | P2X7 | retina | glaucoma | ATP release | mechanical strain | TBI | astrocytes | IOP | neurons | IL-6
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 08/2019
Journal Article
Investigative Opthalmology & Visual Science, ISSN 1552-5783, 07/2019, Volume 60, Issue 8, pp. 3046 - 3053
PurposeAccumulation of lysosomal waste is linked to neurodegeneration in multiple diseases, and pharmacologic enhancement of lysosomal activity is hypothesized... 
retinal dystrophy | Physiology and Pharmacology | protection | drug delivery | lysosome | ABCA4
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