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by Lotta, Luca A and Gulati, Pawan and Day, Felix R and Payne, Felicity and Ongen, Halit and van de Bunt, Martijn and Gaulton, Kyle J and Eicher, John D and Sharp, Stephen J and Luan, Jian'an and de Lucia Rolfe, Emanuella and Stewart, Isobel D and Wheeler, Eleanor and Willems, Sara M and Adams, Claire and Yaghootkar, Hanieh and Forouhi, Nita G and Khaw, Kay-Tee and Johnson, Anew D and Semple, Robert K and Frayling, Timothy and Perry, John R. B and Dermitzakis, Emmanouil and McCarthy, Mark I and Barroso, Inês and Wareham, Nicholas J and Savage, David B and Langenberg, Claudia and O'Rahilly, Stephen and Scott, Robert A and Kerrison, Nicola D and Sims, Matt and Lucarelli, Debora M. E and Deloukas, Panos and Arriola, Larraitz and Balkau, Beverley and Barricarte, Aurelio and Boeing, Heiner and Franks, Paul W and Gonzalez, Carlos and Grioni, Sara and Kaaks, Rudolf and Key, Timothy J and Navarro, Carmen and Nilsson, Peter M and Overvad, Kim and Palli, Domenico and Panico, Salvatore and Quirós, J. Ramón and Rolandsson, Olov and Sacerdote, Carlotta and Salamanca-Fernández, Elena and Slimani, Nadia and Tjonneland, Anne and Tumino, Rosario and Spijkerman, Annemieke M. W and van der A, Daphne L and van der Schouw, Yvonne T and Riboli, Elio and Stears, Anna and George, Stella and Walker, Mark and Gurnell, Ellie and Maguire, Deire and Mukhtar, Rasha and Nag, Sath and Adler, Amanda and Soeters, Maarten R and Laji, Ken and Watt, Alistair and Aylwin, Simon and Johnson, Anew and Rayman, Gerry and Hanna, Fahmy and Ellard, Sian and Ross, Richard and Blaslov, Kristina and Duvnjak, Lea Smirčić and Cambridge FPLD1 Consortium and EPIC-InterAct Consortium and Lund University and EpiHealth: Epidemiology for Health and Institutionen för kliniska vetenskaper, Malmö and Genetic and Molecular Epidemiology and Genetisk och molekylär epidemiologi and Lunds universitet and EXODIAB: Excellence in Diabetes Research in Sweden and Department of Clinical Sciences, Malmö
Nature genetics, ISSN 1061-4036, 2017, Volume 49, Issue 1, pp. 17 - 26
Journal Article
by Wessel, Jennifer and Chu, Auey Y and Willems, Sara and Wang, Shuai and Yaghootkar, Hanieh and Brody, Jennifer and Dauriz, Marco and Hivert, Marie-France and Raghavan, Sridharan and Lipovich, Leonard and Hidalgo, Bertha and Fox, Keolu and Huffman, Jennifer and An, Ping and Lu, Yingchang and Rasmussen-Torvik, Laura and Grarup, Niels and Ehm, Margaret G and Li, Li and Balidge, Abigail S and Stancáková, Alena and Abrol, Ravinder and Besse, Céline and Boland, Anne and Bork-Jensen, Jette and Fornage, Myriam and Freitag, Christine and Garcia, Melissa and Guo, Xiuqing and Hara, Kazuo and Isaacs, Aaron and Jakobsdottir, Margret and Lange, Leslie and Layton, Jill C and Li, Man and Zhao, Jing Hua and Meidtner, Karina and Morrison, Alanna and Nalls, Michael and Peters, Marjolein and Sabater-Lleal, Maria and Schurmann, Claudia and Silveira, Angela and Smith, G.D and Southam, Lorraine and Stoiber, Marcus H and Strawbridge, Rona and Taylor, Kent and Varga, Tibor V and Allin, Kristine H and Amin, Najaf and Aponte, Jennifer L and Aung, Tin and Barbieri, Caterina and Bihlmeyer, Nathan A and Boehnke, Michael and Bombieri, Cristina and Bowden, Donald and Burns, Sean M and Chen, Yuning and Chen, Yii-Deri and Cheng, Ching-Yu and Correa, D.D and Czajkowski, Jacek and Dehghan, Abbas and Ehret, Georg and Eiriksdottir, Gudny and Escher, Stefan A and Farmaki, Aliki-Eleni and Frånberg, Mattias and Gambaro, Giovanni and Giulianini, Franco and Goddard, William A and Goel, Anuj and Gottesman, Rebecca and Grove, Megan and Gustafsson, Stefan and Hai, Yang and Hallmans, Göran and Heo, Jiyoung and Hoffmann, Per and Ikram, Kamran and Jensen, Richard and Jørgensen, Marit and Jorgensen, Torben and Karaleftheri, Maria and Khor, C.C and Kirkpatrick, Anea and Kraja, Aldi and Kuusisto, Johanna and Lange, Ethan and Lee, I.T and Lee, Wen-Jane and Leong, Aaron and Liao, Jie and Liu, Chunyu and Liu, Yongmei and Lindgren, Cecilia and Linneberg, Allan and Malerba, Giovanni and ... and The EPIC-InterAct Consortium and EPIC-InterAct Consortium and Numerisk analys och datalogi (NADA) and Naturvetenskapliga fakulteten and Stockholms universitet and Science for Life Laboratory (SciLifeLab)
Nature Communications, ISSN 2041-1723, 01/2015, Volume 6, Issue 1, p. 5897
Journal Article
by Lotta, Luca A and Gulati, Pawan and Day, Felix R and Payne, Felicity and Ongen, Halit and Van De Bunt, Martijn and Gaulton, Kyle J and Eicher, John D and Sharp, Stephen J and Luan, Jian'an and De Lucia Rolfe, Emanuella and Stewart, Isobel D and Wheeler, Eleanor and Willems, Sara M and Adams, Claire and Yaghootkar, Hanieh and Forouhi, Nita G and Kerrison, Nicola D and Sims, Matt and Lucarelli, Debora M E and Deloukas, Panos and McCarthy, Mark I and Arriola, Larraitz and Balkau, Beverley and Barricarte, Aurelio and Boeing, Heiner and Franks, Paul W and Gonzalez, Carlos and Grioni, Sara and Kaaks, Rudolf and Key, Timothy J and Navarro, Carmen and Nilsson, Peter M and Overvad, Kim and Palli, Domenico and Panico, Salvatore and Quirós, J. Ramón and Rolandsson, Olov and Sacerdote, Carlotta and Salamanca-Fernández, Elena and Slimani, Nadia and Tjonneland, Anne and Tumino, Rosario and Spijkerman, Annemieke M W and Van Der A, Daphne L and Van Der Schouw, Yvonne T and Riboli, Elio and Semple, Robert K and Stears, Anna and George, Stella and Walker, Mark and Gurnell, Ellie and Maguire, Deire and Mukhtar, Rasha and Nag, Sath and Adler, Amanda and Soeters, Maarten R and Laji, Ken and Watt, Alistair and Aylwin, Simon and Johnson, Anew and Rayman, Gerry and Hanna, Fahmy and Ellard, Sian and Ross, Richard and Blaslov, Kristina and Duvnjak, Lea Smirčić and Khaw, Kay Tee and Johnson, Anew D and Frayling, Timothy and Perry, John R B and Dermitzakis, Emmanouil and Barroso, Inês and Wareham, Nicholas J and Savage, David B and Langenberg, Claudia and O'Rahilly, Stephen and Scott, Robert A
Nature Genetics, ISSN 1061-4036, 01/2017, Volume 49, Issue 1, p. 17
Insulin resistance is a key mediator of obesity-related cardiometabolic disease, yet the mechanisms underlying this link remain obscure. Using an integrative... 
Body Mass Index | Obesity | Cardiovascular Diseases | Genome-Wide Association Study | Humans | Genomics | Metabolic Diseases | Insulin Resistance | Blood Glucose | Male | Cambridge FPLD1 Consortium | Case-Control Studies | EPIC-InterAct Consortium | Phenotype | Animals | Female | Mice | Adipose Tissue | Disease Models, Animal
Journal Article
by Wessel, Jennifer and Chu, Auey Y and Willems, Sara M and Wang, Shuai and Yaghootkar, Hanieh and Brody, Jennifer A and Dauriz, Marco and Hivert, Marie-France and Raghavan, Sridharan and Lipovich, Leonard and Hidalgo, Bertha and Fox, Keolu and Huffman, Jennifer E and An, Ping and Lu, Yingchang and Rasmussen-Torvik, Laura J and Grarup, Niels and Ehm, Margaret G and Li, Li and Balidge, Abigail S and Stancakova, Alena and Abrol, Ravinder and Besse, Celine and Boland, Anne and Bork-Jensen, Jette and Fornage, Myriam and Freitag, Daniel F and Garcia, Melissa E and Guo, Xiuqing and Hara, Kazuo and Isaacs, Aaron and Jakobsdottir, Johanna and Lange, Leslie A and Layton, Jill C and Li, Man and Zhao, Jing Hua and Meidtner, Karina and Morrison, Alanna C and Nalls, Mike A and Peters, Marjolein J and Sabater-Lleal, Maria and Schurmann, Claudia and Silveira, Angela and Smith, Albert V and Southam, Lorraine and Stoiber, Marcus H and Strawbridge, Rona J and Taylor, Kent D and Varga, Tibor V and Allin, Kristine H and Amin, Najaf and Aponte, Jennifer L and Aung, Tin and Barbieri, Caterina and Bihlmeyer, Nathan A and Boehnke, Michael and Bombieri, Cristina and Bowden, Donald W and Burns, Sean M and Chen, Yuning and Chen, Yii-Deri and Cheng, Ching-Yu and Correa, Adolfo and Czajkowski, Jacek and Dehghan, Abbas and Ehret, Georg B and Eiriksdottir, Gudny and Escher, Stefan A and Farmaki, Aliki-Eleni and Franberg, Mattias and Gambaro, Giovanni and Giulianini, Franco and Goddard, William A and Goel, Anuj and Gottesman, Omri and Grove, Megan L and Gustafsson, Stefan and Hai, Yang and Hallmans, Goeran and Heo, Jiyoung and Hoffmann, Per and Ikram, Mohammad K and Jensen, Richard A and Jorgensen, Marit E and Jorgensen, Torben and Karaleftheri, Maria and Khor, Chiea C and Kirkpatrick, Anea and Kraja, Aldi T and Kuusisto, Johanna and Lange, Ethan M and Lee, I. T and Lee, Wen-Jane and Leong, Aaron and Liao, Jiemin and Liu, Chunyu and Liu, Yongmei and Lindgren, Cecilia M and Linneberg, Allan and Malerba, Giovanni and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Enheten för biobanksforskning and Näringsforskning and Umeå universitet and Medicin
Nature Communications [E], ISSN 2041-1723, 01/2015, Volume 6
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants... 
Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
by Wessel, Jennifer and Chu, Audrey Y and Willems, Sara M and Wang, Shuai and Yaghootkar, Hanieh and Brody, Jennifer A and Dauriz, Marco and Hivert, Marie-France and Raghavan, Sridharan and Lipovich, Leonard and Hidalgo, Bertha and Fox, Keolu and Huffman, Jennifer E and An, Ping and Lu, Yingchang and Rasmussen-Torvik, Laura J and Grarup, Niels and Ehm, Margaret G and Li, Li and Baldridge, Abigail S and Stancakova, Alena and Abrol, Ravinder and Besse, Celine and Boland, Anne and Bork-Jensen, Jette and Fornage, Myriam and Freitag, Daniel F and Garcia, Melissa E and Guo, Xiuqing and Hara, Kazuo and Isaacs, Aaron and Jakobsdottir, Johanna and Lange, Leslie A and Layton, Jill C and Li, Man and Zhao, Jing Hua and Meidtner, Karina and Morrison, Alanna C and Nalls, Mike A and Peters, Marjolein J and Sabater-Lleal, Maria and Schurmann, Claudia and Silveira, Angela and Smith, Albert V and Southam, Lorraine and Stoiber, Marcus H and Strawbridge, Rona J and Taylor, Kent D and Varga, Tibor V and Allin, Kristine H and Amin, Najaf and Aponte, Jennifer L and Aung, Tin and Barbieri, Caterina and Bihlmeyer, Nathan A and Boehnke, Michael and Bombieri, Cristina and Bowden, Donald W and Burns, Sean M and Chen, Yuning and Chen, Yii-Deri and Cheng, Ching-Yu and Correa, Adolfo and Czajkowski, Jacek and Dehghan, Abbas and Ehret, Georg B and Eiriksdottir, Gudny and Escher, Stefan A and Farmaki, Aliki-Eleni and Franberg, Mattias and Gambaro, Giovanni and Giulianini, Franco and Goddard, William A., III and Goel, Anuj and Gottesman, Omri and Grove, Megan L and Gustafsson, Stefan and Hai, Yang and Hallmans, Goeran and Heo, Jiyoung and Hoffmann, Per and Ikram, Mohammad K and Jensen, Richard A and Jorgensen, Marit E and Jorgensen, Torben and Karaleftheri, Maria and Khor, Chiea C and Kirkpatrick, Andrea and Kraja, Aldi T and Kuusisto, Johanna and Lange, Ethan M and Lee, I. T and Lee, Wen-Jane and Leong, Aaron and Liao, Jiemin and Liu, Chunyu and Liu, Yongmei and Lindgren, Cecilia M and Linneberg, Allan and Malerba, Giovanni and ... and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Nature Communications, ISSN 2041-1723, 2015, Volume 6
Fasting glucose and insulin are intermediate traits for type 2 diabetes. Here we explore the role of coding variation on these traits by analysis of variants... 
Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Medicin och hälsovetenskap | Klinisk medicin | Endocrinology and Diabetes
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 9859 - 11
The accurate assessment of dietary intake is crucial to investigate the effect of diet on health. Currently used methods, relying on self-reporting and food... 
WOMEN | DIETARY POLYPHENOLS | EPIC-NORFOLK | (-)-EPICATECHIN | PLASMA | MULTIDISCIPLINARY SCIENCES | URINARY-EXCRETION | STANDARDS | END-POINTS | CHEMICAL-SYNTHESIS | COHORT | Wine | Tea | Metabolites | Food intake | Microbiomes | Biomarkers | Food composition | Dietary intake | Epidemiology | Cocoa
Journal Article
Scientific reports, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 13108 - 10
Data from dietary intervention studies suggest that intake of (-)-epicatechin mediates beneficial vascular effects in humans. However, population-based... 
VALIDATION | CHEMICAL-SYNTHESIS | GLUCURONIDES | EPICATECHIN | MULTIDISCIPLINARY SCIENCES | Urine | Metabolites | Biomarkers | Dietary intake | Sulfate | Cocoa | Epicatechin
Journal Article