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Nature Cell Biology, ISSN 1465-7392, 08/2017, Volume 19, Issue 8, pp. 889 - 890
Mutations in AT rich interactive domain 1A (ARID1A) are common in ovarian cancers. A study now shows that HDAC6 activity is required for survival of ovarian... 
ARID1A | MUTATIONS | CELL BIOLOGY | Ovarian Neoplasms - genetics | Histone Deacetylases - genetics | Humans | Female | Mutation | Transcription Factors - genetics | Nuclear Proteins - genetics | Physiological aspects | Development and progression | Genetic aspects | Research | Gene mutations | Ovarian cancer | Cell survival | Ovarian carcinoma | Inhibition | Apoptosis | Cancer | Index Medicus
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 02/2019, Volume 11, Issue 2, pp. e10116 - n/a
L. Altucci and R. Benedetti discuss the study by Chua et al (in this issue of EMBO Molecular Medicine), in which co‐targeting of FGFR signaling increases the... 
MEDICINE, RESEARCH & EXPERIMENTAL | INHIBITORS | Uveal Neoplasms | Fibroblast Growth Factor 2 | Humans | Melanoma | Medical research | Cell culture | Liver | Clinical trials | Genomes | Metastasis | Kinases | Patients | Ovarian cancer | Metastases | Medical prognosis | Fibroblast growth factor receptors | Tumors | Cancer | Index Medicus | Views
Journal Article
STEM CELLS, ISSN 1066-5099, 01/2014, Volume 32, Issue 1, pp. 279 - 289
Adult mesenchymal stem cells, such as dental pulp stem cells, are of great interest for cell‐based tissue engineering strategies because they can differentiate... 
Valproic acid | DPSC | Osteogenesis | HDAC | ACETYLATION | CRYOPRESERVATION | MATURATION | RUNX2 | CELL & TISSUE ENGINEERING | CELL BIOLOGY | REPRESSES | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | BONE | DIFFERENTIATION | HEMATOLOGY | ACETYLTRANSFERASES | TRANSFORMED-CELLS | Mesenchymal Stromal Cells - enzymology | Apoptosis - drug effects | Humans | Osteocalcin - genetics | Osteopontin - metabolism | Dental Pulp - metabolism | Valproic Acid - pharmacology | Mesenchymal Stromal Cells - cytology | Transfection | Dental Pulp - enzymology | Histone Deacetylase 1 - antagonists & inhibitors | Osteoblasts - cytology | Mesenchymal Stromal Cells - drug effects | Osteocalcin - biosynthesis | Osteoblasts - enzymology | Histone Deacetylase 2 - antagonists & inhibitors | Osteoblasts - drug effects | Dental Pulp - cytology | Mesenchymal Stromal Cells - metabolism | Dental Pulp - drug effects | Down-Regulation - drug effects | Cell Differentiation - drug effects | Histone Deacetylase Inhibitors - pharmacology | Histone Deacetylase 2 - metabolism | Cell Cycle - drug effects | Osteoblasts - metabolism | Histone Deacetylase 1 - metabolism | Enzymes | Divalproex | RNA | Tissue engineering | Analysis | Gene expression | Bone marrow | Stem cells | Index Medicus | Epigenetics, Genomics, Proteomics, and Metabonomics | Stem Cell Technology
Journal Article
Journal Article
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 2012, Volume 3, pp. 4 - 4
Sirtuins represent a promising new class of conserved histone deacetylases, originally identified in yeast. The activity of the sirtuin (SAT) family made up of... 
Sirtuins | Epigenetics | Human diseases | SirT inhibitors | Cancer | LIFE-SPAN | MECHANISM | ACETYLATION | sirtuins | DEACETYLASES | human diseases | SIRT1 ACTIVATION | epigenetics | NAD | INHIBITION | PHARMACOLOGY & PHARMACY | cancer | TUMORIGENESIS | EXPRESSION | Sirt inhibitors
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 49, pp. 19183 - 19187
The overlapping histological and biochemical features underlying the beneficial effect of deacetylase inhibitors and NO donors in dystrophic muscles suggest an... 
Artificial satellites | Duchenne muscular dystrophy | Muscles | Small interfering RNA | Histones | Oxides | Muscular dystrophies | Pharmacology | Skeletal muscle | Myoblasts | Epigenetic | RECRUITMENT | COMPLEX | SKELETAL-MUSCLE MASS | FUSION | epigenetic | MULTIDISCIPLINARY SCIENCES | INDUCTION | MDX MICE | SYNTHASE | SIGNALING PATHWAY | GENE-EXPRESSION | skeletal muscle | FOLLISTATIN | Muscular Dystrophy, Animal - drug therapy | Epigenesis, Genetic | Muscle, Skeletal - cytology | Muscular Dystrophy, Animal - pathology | Repressor Proteins - antagonists & inhibitors | Mice, Inbred mdx | Muscular Dystrophy, Animal - metabolism | Myoblasts - cytology | Benzamides - pharmacology | Repressor Proteins - metabolism | Nitrogen - metabolism | Histone Deacetylases - genetics | Muscular Dystrophy, Duchenne - drug therapy | Mice, Inbred C57BL | Satellite Cells, Skeletal Muscle - cytology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Repressor Proteins - genetics | Histone Deacetylase 2 | Histone Deacetylases - metabolism | Muscular Dystrophy, Duchenne - pathology | Satellite Cells, Skeletal Muscle - enzymology | Animals | Histone Deacetylase Inhibitors | Mice | Muscular Dystrophy, Duchenne - metabolism | Pyridines - pharmacology | RNA, Small Interfering | Nitric Oxide - metabolism | Myoblasts - enzymology | Musculoskeletal system | Biochemistry | Mutation | Gene expression | Rodents | Nitric oxide | Index Medicus | Biological Sciences
Journal Article