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Science, ISSN 0036-8075, 07/2017, Volume 357, Issue 6349, pp. 409 - 413
The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of somatic mutations. In a proof-of-concept study, we previously showed... 
CELL LUNG-CANCER | SURVIVAL | COLORECTAL CARCINOMAS | RECEIVING NIVOLUMAB | IMMUNOTHERAPY | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | NEOANTIGENS | CHECKPOINT BLOCKADE | LYMPHOCYTES | Neoplastic Syndromes, Hereditary - immunology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Neoplastic Syndromes, Hereditary - mortality | Young Adult | Colorectal Neoplasms - therapy | Brain Neoplasms - immunology | DNA Mismatch Repair | Aged, 80 and over | Adult | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Biomarkers, Tumor - antagonists & inhibitors | Colorectal Neoplasms - mortality | Antibodies, Monoclonal, Humanized - therapeutic use | Antigens, Neoplasm - immunology | Brain Neoplasms - genetics | Disease-Free Survival | Colorectal Neoplasms - immunology | Cell Cycle Checkpoints - drug effects | Brain Neoplasms - therapy | Neoplastic Syndromes, Hereditary - therapy | T-Lymphocytes - immunology | Aged | Mutation | Programmed Cell Death 1 Receptor - immunology | Colorectal cancer | Genetic aspects | Nucleotide sequencing | Health aspects | DNA repair | Methods | Tumors | DNA sequencing | Yeast | PD-1 protein | Antibodies | Clinical trials | Genomes | Functional analysis | Lymphocytes T | Patients | Survival | Colon cancer | Immune checkpoint | Immunotherapy | Mismatch repair | Pancreatic cancer | Biomarkers | Bioindicators | Colon | Solid tumors | Genetic recombination | Repair | Cancer | Apoptosis | Index Medicus
Journal Article
Science, ISSN 0036-8075, 02/2018, Volume 359, Issue 6378, pp. 926 - 930
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e93102 - e93102
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 48, pp. E7769 - E7777
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e78127 - e78127
Head and neck squamous cell carcinoma (HNSCC) is largely divided into two groups based on their etiology, human papillomavirus (HPV)-positive and -negative.... 
EXPRESSION DIFFERENCES | SURVIVAL | HEAD | METHYLATION | MULTIDISCIPLINARY SCIENCES | RESISTANCE | PATTERNS | HUMAN-PAPILLOMAVIRUS | NECK-CANCER | DISCOVERY | REVEALS | Head and Neck Neoplasms - virology | Oligonucleotide Array Sequence Analysis | DNA, Neoplasm - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Carcinoma, Squamous Cell - virology | Epigenesis, Genetic | Humans | Gene Expression Regulation, Neoplastic | Hedgehog Proteins - metabolism | Male | Papillomavirus Infections - pathology | DNA Methylation | Squamous Cell Carcinoma of Head and Neck | Hedgehog Proteins - genetics | Female | Papillomavirus Infections - virology | Papillomaviridae - physiology | Papillomavirus Infections - complications | Signal Transduction | Transcription Factors - genetics | Head and Neck Neoplasms - pathology | Papillomavirus Infections - genetics | Papillomaviridae - pathogenicity | Transcription Factors - metabolism | Carcinoma, Squamous Cell - complications | Head and Neck Neoplasms - complications | Head and Neck Neoplasms - genetics | Zinc Finger Protein GLI1 | DNA, Neoplasm - genetics | Neoplasm Staging | Cluster Analysis | Epigenetic inheritance | Squamous cell carcinoma | Analysis | Genes | Genetic research | Development and progression | Genetic transcription | Methylation | Papillomavirus infections | Deregulation | Head | Transcription | Otolaryngology | Oncology | Genomes | Gene expression | Human papillomavirus | Pathways | Etiology | Transcription activation | Cell cycle | DNA methylation | Epigenetics | Tumor suppressor genes | Head and neck cancer | Neck | Mutation | Head & neck cancer | Arrays | Deoxyribonucleic acid--DNA | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
by Hill, Steven M and Heiser, Laura M and Cokelaer, Thomas and Linger, Michael and Nesser, Nicole K and Carlin, Daniel E and Zhang, Yang and Sokolov, Artem and Paull, Evan O and Wong, Chris K and Graim, Kiley and Bivol, Adrian and Wang, Haizhou and Zhu, Fan and Afsari, Bahman and Danilova, Ludmila V and Favorov, Alexander V and Lee, Wai Shing and Taylor, Dane and Hu, Chenyue W and Long, Byron L and Noren, David P and Bisberg, Alexander J and Mills, Gordon B and Gray, Joe W and Kellen, Michael and Norman, Thea and Friend, Stephen and Qutub, Amina A and Fertig, Elana J and Guan, Yuanfang and Song, Mingzhou and Stuart, Joshua M and Spellman, Paul T and Koeppl, Heinz and Stolovitzky, Gustavo and Saez-Rodriguez, Julio and Mukherjee, Sach and Al-Ouran, Rami and Anton, Bernat and Arodz, Tomasz and Sichani, Omid Askari and Bagheri, Neda and Berlow, Noah and Bohler, Anwesha and Bonet, Jaume and Bonneau, Richard and Budak, Gungor and Bunescu, Razvan and Caglar, Mehmet and Cai, Binghuang and Cai, Chunhui and Carlon, Azzurra and Chen, Lujia and Ciaccio, Mark F and Cooper, Gregory and Coort, Susan and Creighton, Chad J and Daneshmand, Seyed-Mohammad-Hadi and De La Fuente, Alberto and Di Camillo, Barbara and Dutta-Moscato, Joyeeta and Emmett, Kevin and Evelo, Chris and Fassia, Mohammad-Kasim H and Finotello, Francesca and Finkle, Justin D and Gao, Xi and Garcia-Garcia, Javier and Ghosh, Samik and Giaretta, Alberto and Großeholz, Ruth and Guinney, Justin and Hafemeister, Christoph and Hahn, Oliver and Haider, Saad and Hase, Takeshi and Hodgson, Jay and Hoff, Bruce and Hsu, Chih Hao and Hu, Ying and Huang, Xun and Jalili, Mahdi and Jiang, Xia and Kacprowski, Tim and Kaderali, Lars and Kang, Mingon and Kannan, Venkateshan and Kikuchi, Kaito and Kim, Dong-Chul and Kitano, Hiroaki and Knapp, Bettina and Komatsoulis, George and Krämer, Andreas and Kursa, Miron Bartosz and Kutmon, Martina and Li, Yichao and Liang, Xiaoyu and Liu, Zhaoqi and Liu, Yu and ... and HPN-DREAM Consortium and The HPN-DREAM Consortium
Nature Methods, ISSN 1548-7091, 03/2016, Volume 13, Issue 4, pp. 310 - 322
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15544 - 15549
Journal Article