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1. Full Text MicroRNA‐151 and its hosting gene FAK (focal adhesion kinase) regulate tumor cell migration and spreading of hepatocellular carcinoma
by Luedde, Tom
Hepatology, ISSN 0270-9139, 09/2010, Volume 52, Issue 3, pp. 1162 - 1164
Recurrent chromosomal aberrations are often observed in hepatocellular carcinoma (HCC), but little is known about the functional non‐coding sequences,... 
Liver cancer | Metastasis | MicroRNAs | Cell adhesion & migration
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2. Full Text Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
by Galluzzi, Lorenzo and Vitale, Ilio and Aaronson, Stuart A and Abrams, John M and Adam, Dieter and Agostinis, Patrizia and Alnemri, Emad S and Altucci, Lucia and Amelio, Ivano and Anews, David W and Annicchiarico-Petruzzelli, Margherita and Antonov, Alexey V and Arama, Eli and Baehrecke, Eric H and Barlev, Nickolai A and Bazan, Nicolas G and Bernassola, Francesca and Bertrand, Mathieu J. M and Bianchi, Katiuscia and Blagosklonny, Mikhail V and Blomgren, Klas and Borner, Christoph and Boya, Patricia and Brenner, Catherine and Campanella, Michelangelo and Candi, Eleonora and Carmona-Gutierrez, Didac and Cecconi, Francesco and Chan, Francis K.-M and Chandel, Navdeep S and Cheng, Emily H and Chipuk, Jerry E and Cidlowski, John A and Ciechanover, Aaron and Cohen, Gerald M and Conrad, Marcus and Cubillos-Ruiz, Juan R and Czabotar, Peter E and D'Angiolella, Vincenzo and Dawson, Ted M and Dawson, Valina L and de Laurenzi, Vincenzo and de Maria, Ruggero and Debatin, Klaus-Michael and DeBerardinis, Ralph J and Deshmukh, Mohanish and Di Daniele, Nicola and Di Virgilio, Francesco and Dixit, Vishva M and Dixon, Scott J and Duckett, Colin S and Dynlacht, Brian D and El-Deiry, Wafik S and Elrod, John W and Fimia, Gian Maria and Fulda, Simone and García-Sáez, Ana J and Garg, Abhishek D and Garrido, Carmen and Gavathiotis, Evripidis and Golstein, Pierre and Gottlieb, Eyal and Green, Douglas R and Greene, Lloyd A and Gronemeyer, Hinrich and Gross, Atan and Hajnoczky, Gyorgy and Hardwick, J. Marie and Harris, Isaac S and Hengartner, Michael O and Hetz, Claudio and Ichijo, Hidenori and Jäättelä, Marja and Joseph, Bertrand and Jost, Philipp J and Juin, Philippe P and Kaiser, William J and Karin, Michael and Kaufmann, Thomas and Kepp, Oliver and Kimchi, Adi and Kitsis, Richard N and Klionsky, Daniel J and Knight, Richard A and Kumar, Sharad and Lee, Sam W and Lemasters, John J and Levine, Beth and Linkermann, Aneas and Lipton, Stuart A and Lockshin, Richard A and López-Otín, Carlos and Lowe, Scott W and Luedde, Tom and Lugli, Enrico and MacFarlane, Marion and Madeo, Frank and Malewicz, Michal and Malorni, Walter and Manic, Gwenola and ...
Cell death and differentiation, ISSN 1350-9047, 2018, Volume 25, Issue 3, pp. 486 - 541
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated guidelines for the definition and interpretation of cell death from... 
BCL-2 FAMILY-MEMBER | MITOCHONDRIAL PERMEABILITY TRANSITION | TUMOR-NECROSIS-FACTOR | NEUTROPHIL EXTRACELLULAR TRAPS | LYSOSOMAL MEMBRANE PERMEABILIZATION | GLUTATHIONE-PEROXIDASE 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | MIXED LINEAGE KINASE | NONCANONICAL INFLAMMASOME ACTIVATION | CYTOCHROME-C RELEASE | NF-KAPPA-B | CELL BIOLOGY | Mitochondrial Membrane Transport Proteins - metabolism | Animals | Lysosomes - metabolism | Humans | Cell Death | Lysosomes - pathology | Necrosis - metabolism | Necrosis - pathology | Mitochondria | Senescence | Molecular modelling | Immunogenicity | Cell death | Nomenclature | Mitochondrial DNA | Permeability | Autophagy | Phagocytosis | Apoptosis | Life Sciences | Cancer | Review
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3. Full Text Life is fragile: FMRP controls cell death in liver disease
by Vucur, Mihael and Luedde, Tom
Gut, ISSN 0017-5749, 9/2019, p. gutjnl-2019-319534
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4. Full Text Elevated serum levels of bone sialoprotein (BSP) predict long-term mortality in patients with pancreatic adenocarcinoma
by Loosen, Sven H and Hoening, Pia and Puethe, Niklas and Luedde, Mark and Spehlmann, Martina and Ulmer, Tom F and Cardenas, David V and Roy, Sanchari and Tacke, Frank and Trautwein, Christian and Neumann, Ulf P and Luedde, Tom and Roderburg, Christoph
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1489 - 8
Patients with pancreatic adenocarcinoma (PDAC) still face a very limited prognosis. At early stage, surgical tumor resection might offer long-term survival but... 
OSTEOPONTIN | CANCER-ASSOCIATED FIBROBLASTS | TUMOR-MARKERS | MULTIDISCIPLINARY SCIENCES | GROWTH | SIBLINGS | PROTEINS | Adenocarcinoma | Serum levels | Medical prognosis | Bone sialoprotein | Bone (long) | Pancreas | Bone surgery | Survival | Enzyme-linked immunosorbent assay | Tumors
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5. Full Text Tracheobronchial transplantation with a stem-cell-seeded bioartificial nanocomposite: a proof-of-concept study
by Jungebluth, Philipp, MD and Alici, Evren, MD and Baiguera, Silvia, PhD and Blomberg, Pontus, PhD and Bozóky, Béla, MD and Crowley, Claire, MSc and Einarsson, Oskar, MD and Gudbjartsson, Tomas, Prof and Le Guyader, Sylvie, PhD and Henriksson, Gert, MD and Hermanson, Ola, PhD and Juto, Jan Erik, MD and Leidner, Bertil, MD and Lilja, Tobias, PhD and Liska, Jan, MD and Luedde, Tom, MD and Lundin, Vanessa, MS and Moll, Guido, MS and Roderburg, Christoph, MD and Strömblad, Staffan, Prof and Sutlu, Tolga, BSc and Watz, Emma, MD and Seifalian, Alexander, Prof and Macchiarini, Paolo, Prof and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Klinisk immunologi and Uppsala universitet
Lancet, The, ISSN 0140-6736, 2011, Volume 378, Issue 9808, pp. 1997 - 2004
Summary Background Tracheal tumours can be surgically resected but most are an inoperable size at the time of diagnosis; therefore, new therapeutic options are... 
Internal Medicine | AIRWAY COMPLICATIONS | MEDICINE, GENERAL & INTERNAL | LUNG TRANSPLANTATION | MANAGEMENT | MOBILIZATION | RESECTION | BONE-MARROW | GRAFT | TUMORS | Recombinant Proteins - therapeutic use | Leukocytes, Mononuclear - metabolism | Cell Proliferation | Nanocomposites - chemistry | Erythropoietin - therapeutic use | Humans | Male | MicroRNAs - metabolism | Transplantation, Autologous | Blood Vessel Prosthesis | Neoplasm Recurrence, Local - surgery | Tissue Scaffolds | Polyethylene Terephthalates | Flow Cytometry | Bone Marrow Transplantation | Leukocytes, Mononuclear - transplantation | Adult | Bronchial Neoplasms - surgery | Epoetin Alfa | Bronchoscopy | Tissue Engineering - methods | Carcinoma, Mucoepidermoid - surgery | Hematopoietic Stem Cells - metabolism | Granulocyte Colony-Stimulating Factor - therapeutic use | Regeneration | Bioreactors | Tracheal Neoplasms - surgery | Neovascularization, Physiologic | Care and treatment | Diagnosis | Research | Tumors | Transplantation | Analysis | Nanotechnology | Stem cells | Studies | Bone marrow | Postoperative period | Mortality | Medical and Health Sciences | Medicin och hälsovetenskap
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6. Full Text Apoptosis and necroptosis in the liver: a matter of life and death
by Schwabe, Robert F and Luedde, Tom
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 12/2018, Volume 15, Issue 12, pp. 738 - 752
Cell death represents a basic biological paradigm that governs outcomes and long-term sequelae in almost every hepatic disease condition. Acute liver failure... 
PROGRAMMED CELL-DEATH | HEPATOCYTE APOPTOSIS | TUMOR-NECROSIS-FACTOR | HEPATOCELLULAR-CARCINOMA | CLINICAL-TRIAL | NLRP3 INFLAMMASOME ACTIVATION | MIXED LINEAGE KINASE | NONALCOHOLIC STEATOHEPATITIS | PAN-CASPASE INHIBITOR | MURINE MODELS | GASTROENTEROLOGY & HEPATOLOGY
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7. Full Text Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance
by Luedde, Tom and Kaplowitz, Neil and Schwabe, Robert F
Gastroenterology, ISSN 0016-5085, 2014, Volume 147, Issue 4, pp. 765 - 783.e4
Hepatocellular death is present in almost all types of human liver disease and is used as a sensitive parameter for the detection of acute and chronic liver... 
Gastroenterology and Hepatology | DILI | Clinical Trial | Necrosome | Viral Hepatitis | NASH | Necrosis | Necroptosis | Alcoholic Liver Disease | Caspases | RIP3 | Apoptosis | DAMP | Hepatocellular Carcinoma | RIP Kinases | Necrosis Necroptosis | Necrosome DAMP Viral | DILI Caspases | Hepatitis NASH Clinical | Trial Hepatocellular Carcinoma | RIP3 RIP Kinases | DOMAIN-LIKE PROTEIN | NONALCOHOLIC STEATOHEPATITIS | ENDOPLASMIC-RETICULUM STRESS | SERUM AMINOTRANSFERASE CONCENTRATION | GROUP BOX-1 PROTEIN | MITOCHONDRIAL PERMEABILITY TRANSITION | HEPATOCELLULAR-CARCINOMA | NF-KAPPA-B | HEPATITIS-C VIRUS | ACUTE ALCOHOLIC HEPATITIS | GASTROENTEROLOGY & HEPATOLOGY | Biomarkers - metabolism | Liver - pathology | Signal Transduction | Humans | Liver - metabolism | Liver Diseases - pathology | Liver Diseases - therapy | Hepatocytes - pathology | Hepatocytes - metabolism | Animals | Liver Diseases - metabolism | Liver cancer | Medical colleges | Development and progression | Biochemistry | Cell death | Liver cirrhosis | Index Medicus | Abridged Index Medicus
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