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1. High-dose ursodeoxycholic acid is associated with the development of colorectal neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis
by Eaton, John E and Silveira, Marina G and Pardi, Darrell S and Sinakos, Emmanouil and Kowdley, Kris V and Luketic, Velimir A. C and Harrison, M Edwyn and McCashland, Timothy and Befeler, Alex S and Harnois, Denise and Jorgensen, Roberta and Petz, Jan and Lindor, Keith D
The American journal of gastroenterology, ISSN 0002-9270, 09/2011, Volume 106, Issue 9, pp. 1638 - 1645
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Cholangitis, Sclerosing - drug therapy | Ursodeoxycholic Acid - administration & dosage | Follow-Up Studies | Humans | Middle Aged | Cholangitis, Sclerosing - complications | Male | Risk | Ursodeoxycholic Acid - adverse effects | Cholagogues and Choleretics - adverse effects | Cholagogues and Choleretics - therapeutic use | Ursodeoxycholic Acid - therapeutic use | Young Adult | Adult | Female | Retrospective Studies | Colitis, Ulcerative - drug therapy | Colitis, Ulcerative - complications | Lithocholic Acid - blood | Cholagogues and Choleretics - administration & dosage | Colorectal Neoplasms - blood | Proportional Hazards Models | Chenodeoxycholic Acid - blood | Colorectal Neoplasms - chemically induced | Adolescent | Aged | Colorectal Neoplasms - complications | Colorectal Neoplasms - pathology
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2. Full Text High‐dose ursodeoxycholic acid for the treatment of primary sclerosing cholangitis
by Lindor, Keith D and Kowdley, Kris V and Luketic, Velimir A. C and Harrison, M. Edwyn and McCashland, Timothy and Befeler, Alex S and Harnois, Denise and Jorgensen, Roberta and Petz, Jan and Keach, Jill and Mooney, Jody and Sargeant, Carol and Braaten, Julie and Bernard, Tamara and King, Debra and Miceli, Ellen and Schmoll, Jeff and Hoskin, Tanya and Thapa, Prabin and Enders, Felicity
Hepatology (Baltimore, Md.), ISSN 0270-9139, 09/2009, Volume 50, Issue 3, pp. 808 - 814
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Biological and medical sciences | Medical sciences | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Other diseases. Semiology | Liver Function Tests | Cholangitis, Sclerosing - drug therapy | Ursodeoxycholic Acid - administration & dosage | Liver Transplantation | Double-Blind Method | Humans | Middle Aged | Kaplan-Meier Estimate | Male | Treatment Outcome | Ursodeoxycholic Acid - adverse effects | Cholagogues and Choleretics - therapeutic use | Ursodeoxycholic Acid - therapeutic use | Bilirubin - blood | Aspartate Aminotransferases - blood | Adult | Female | Aged | Alkaline Phosphatase - blood | Cholangitis, Sclerosing - mortality | Index Medicus
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3. Full Text A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis
by Nevens, Frederik and Andreone, Pietro and Mazzella, Giuseppe and Strasser, Simone I and Bowlus, Christopher and Invernizzi, Pietro and Drenth, Joost P.H and Pockros, Paul J and Regula, Jaroslaw and Beuers, Ulrich and Trauner, Michael and Jones, David E and Floreani, Annarosa and Hohenester, Simon and Luketic, Velimir and Shiffman, Mitchell and van Erpecum, Karel J and Vargas, Victor and Vincent, Catherine and Hirschfield, Gideon M and Shah, Hemant and Hansen, Bettina and Lindor, Keith D and Marschall, Hanns-Ulrich and Kowdley, Kris V and Hooshmand-Rad, Roya and Marmon, Tonya and Sheeron, Shawn and Pencek, Richard and MacConell, Leigh and Pruzanski, Mark and Shapiro, David and POISE Study Grp and POISE Study Group and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
The New England journal of medicine, ISSN 0028-4793, 08/2016, Volume 375, Issue 7, pp. 631 - 643
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Liver Cirrhosis - etiology | Bile Acids and Salts - blood | Double-Blind Method | Humans | Middle Aged | Liver Cirrhosis, Biliary - drug therapy | Male | Chenodeoxycholic Acid - analogs & derivatives | Bone Density - drug effects | Chenodeoxycholic Acid - adverse effects | Fibroblast Growth Factors - blood | Chenodeoxycholic Acid - therapeutic use | Adult | Female | Aged | Liver Cirrhosis, Biliary - complications | Liver Cirrhosis, Biliary - blood | Alkaline Phosphatase - blood | Pruritus - chemically induced | Clinical trials | Ursodiol | Care and treatment | Usage | Dosage and administration | Cholangitis | Primary biliary cirrhosis | Alkaline phosphatase | Liver diseases | Syngeneic grafts | Liver | Bilirubin | Pruritus | Phosphatase | Patients | Cirrhosis | Allografts | Acids | Fibrosis | Drug therapy | Bile | Liver transplantation | Index Medicus | Abridged Index Medicus | Alkaline Phosphatase | Chenodeoxycholic Acid | Fibroblast Growth Factors | Gastroenterology and Hepatology | Bone Density | drug therapy | chemically induced | complications | Gastroenterologi | drug effects | Liver Cirrhosis | blood | Bile Acids and Salts | etiology | Biliary | analogs & derivatives | adverse effects | therapeutic use
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4. Full Text The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids
by Puri, Puneet and Daita, Kalyani and Joyce, Andrew and Mirshahi, Faridoddin and Santhekadur, Prasanna K and Cazanave, Sophie and Luketic, Velimir A and Siddiqui, Mohammad S and Boyett, Sherry and Min, Hae‐Ki and Kumar, Divya P and Kohli, Rohit and Zhou, Huiping and Hylemon, Phillip B and Contos, Melissa J and Idowu, Michael and Sanyal, Arun J
Hepatology (Baltimore, Md.), ISSN 0270-9139, 02/2018, Volume 67, Issue 2, pp. 534 - 548
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Bile acids | Liver diseases | Liver | Diabetes mellitus | Mass spectroscopy | Liquid chromatography | Chenodeoxycholate | Steatosis | Cirrhosis | Body mass index | Fatty liver | Acids | Biopsy | Taurolithocholate | Fibrosis | Diabetes | Diabetes mellitus (non-insulin dependent) | Bile | Index Medicus | Cyp 27α hydroxylase | liver fibrosis | Nonalcoholic steatohepatitis | NAFLD activity score | Type 2 Diabetes | Farsenoid X receptor | Cyp 7α hydroxylase | Insulin resistance | Nonalcoholic fatty liver disease | hepatic steatosis
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5. Full Text A randomized trial of obeticholic acid monotherapy in patients with primary biliary cholangitis
by Kowdley, Kris V and Luketic, Velimir and Chapman, Roger and Hirschfield, Gideon M and Poupon, Raoul and Schramm, Christoph and Vincent, Catherine and Rust, Christian and Parés, Albert and Mason, Andrew and Marschall, Hanns‐Ulrich and Shapiro, David and Adorini, Luciano and Sciacca, Cathi and Beecher‐Jones, Tessa and Böhm, Olaf and Pencek, Richard and Jones, David and Obeticholic Acid PBC Monotherapy and Obeticholic Acid PBC Monotherapy Study Group and Sahlgrenska akademin and Institute of Medicine, Department of Molecular and Clinical Medicine and Institutionen för medicin, avdelningen för molekylär och klinisk medicin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy
Hepatology (Baltimore, Md.), ISSN 0270-9139, 05/2018, Volume 67, Issue 5, pp. 1890 - 1902
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Double-Blind Method | Follow-Up Studies | Humans | Middle Aged | Liver Cirrhosis, Biliary - drug therapy | Male | Treatment Outcome | Receptors, Cytoplasmic and Nuclear - agonists | Chenodeoxycholic Acid - analogs & derivatives | Chenodeoxycholic Acid - adverse effects | Cholestasis - etiology | Chenodeoxycholic Acid - therapeutic use | Adult | Female | Cholestasis - drug therapy | Alkaline Phosphatase - blood | Receptors, Cytoplasmic and Nuclear - metabolism | Immunoglobulin M | Alkaline phosphatase | Alanine | g-Glutamyltransferase | Cholangitis | Bilirubin | Pruritus | Phosphatase | Patients | Ursodeoxycholic acid | Acids | Risk assessment | Alanine transaminase | Receptor mechanisms | Cholestasis | Biochemical markers | Index Medicus | Original | Clinical Medicine | Klinisk medicin | Gastroenterology and Hepatology | Gastroenterologi
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6. The multi-dimensional burden of cirrhosis and hepatic encephalopathy on patients and caregivers
by Bajaj, Jasmohan S and Wade, James B and Gibson, Douglas P and Heuman, Douglas M and Thacker, Leroy R and Sterling, Richard K and Stravitz, R. Todd and Luketic, Velimir and Fuchs, Michael and White, Melanie B and Bell, Debulon E and Gilles, Hochong and Morton, Katherine and Noble, Nicole and Puri, Puneet and Sanyal, Arun J
The American journal of gastroenterology, ISSN 0002-9270, 09/2011, Volume 106, Issue 9, pp. 1646 - 1653
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Caregivers - economics | Humans | Middle Aged | Cost of Illness | Male | Liver Cirrhosis - economics | Employment - economics | Adult | Female | Surveys and Questionnaires | Quality of Life - psychology | Cognition Disorders - psychology | Hepatic Encephalopathy - economics | Cross-Sectional Studies | Liver Cirrhosis - complications | Caregivers - psychology | Anxiety - psychology | Veterans - psychology | Hepatic Encephalopathy - complications | Regression Analysis | Cognition Disorders - economics | Depression - psychology | Aged | Employment - psychology | Hepatic Encephalopathy - psychology | Patient Compliance - psychology | Liver Cirrhosis - psychology
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7. Full Text The Stroop smartphone application is a short and valid method to screen for minimal hepatic encephalopathy
by Bajaj, Jasmohan S and Thacker, Leroy R and Heuman, Douglas M and Fuchs, Michael and Sterling, Richard K and Sanyal, Arun J and Puri, Puneet and Siddiqui, Mohammad S and Stravitz, Richard T and Bouneva, Iliana and Luketic, Velimir and Noble, Nicole and White, Melanie B and Monteith, Pamela and Unser, Ariel and Wade, James B
Hepatology (Baltimore, Md.), ISSN 0270-9139, 09/2013, Volume 58, Issue 3, pp. 1122 - 1132
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Reproducibility of Results | Outcome Assessment (Health Care) | Humans | Middle Aged | Cell Phone - instrumentation | Male | Mass Screening - methods | Case-Control Studies | Sensitivity and Specificity | Psychometrics - methods | Hepatic Encephalopathy - diagnosis | Female | ROC Curve | Hepatic Encephalopathy - psychology | Smartphones | Liver cirrhosis | Hepatology | Index Medicus
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8. Full Text Simtuzumab for Primary Sclerosing Cholangitis: Phase 2 Study Results With Insights on the Natural History of the Disease
by Muir, Andrew J and Levy, Cynthia and Janssen, Harry L.A and Montano‐Loza, Aldo J and Shiffman, Mitchell L and Caldwell, Stephen and Luketic, Velimir and Ding, Dora and Jia, Catherine and McColgan, Bryan J and McHutchison, John G and Mani Subramanian, G and Myers, Robert P and Manns, Michael and Chapman, Roger and Afdhal, Nezam H and Goodman, Zachary and Eksteen, Bertus and Bowlus, Christopher L and GS-US-321-0102 Investigators and for the GS‐US‐321‐0102 Investigators
Hepatology (Baltimore, Md.), ISSN 0270-9139, 02/2019, Volume 69, Issue 2, pp. 684 - 698
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Cholangitis, Sclerosing - drug therapy | Liver - pathology | Antibodies, Monoclonal, Humanized - therapeutic use | Double-Blind Method | Humans | Liver - metabolism | Middle Aged | Cholangitis, Sclerosing - complications | Male | Collagen - metabolism | Liver - drug effects | Antibodies, Monoclonal, Humanized - pharmacology | Fibrosis | Cholangitis, Sclerosing - blood | Adult | Female | Alkaline Phosphatase - blood | Alkaline phosphatase | Cirrhosis | Collagen (type I) | Liver diseases | Cholangitis | Monoclonal antibodies | Morphometry | Lysyl oxidase | Patients | Index Medicus
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9. Full Text Proton Pump Inhibitor Initiation and Withdrawal affects Gut Microbiota and Readmission Risk in Cirrhosis
by Bajaj, Jasmohan S and Acharya, Chathur and Fagan, Andrew and White, Melanie B and Gavis, Edith and Heuman, Douglas M and Hylemon, Phillip B and Fuchs, Michael and Puri, Puneet and Schubert, Mitchell L and Sanyal, Arun J and Sterling, Richard K and Stravitz, R Todd and Siddiqui, Mohammad S and Luketic, Velimir and Lee, Hannah and Sikaroodi, Masoumeh and Gillevet, Patrick M
The American journal of gastroenterology, ISSN 0002-9270, 08/2018, Volume 113, Issue 8, pp. 1177 - 1186
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Microbiota | Index Medicus
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10. Covert Hepatic Encephalopathy Is Independently Associated With Poor Survival and Increased Risk of Hospitalization
by Patidar, Kavish R and Thacker, Leroy R and Wade, James B and Sterling, Richard K and Sanyal, Arun J and Siddiqui, Mohammad S and Matherly, Scott C and Stravitz, R Todd and Puri, Puneet and Luketic, Velimir A and Fuchs, Michael and White, Melanie B and Noble, Nicole A and Unser, Ariel B and Gilles, HoChong and Heuman, Douglas M and Bajaj, Jasmohan S
The American journal of gastroenterology, ISSN 0002-9270, 09/2014, Volume 109, Issue 11, pp. 1757 - 1763
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Prospective Studies | Liver Cirrhosis - complications | Hepatic Encephalopathy - mortality | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Risk | Survival Rate | Hepatic Encephalopathy - therapy | Liver Transplantation - statistics & numerical data | Adolescent | Hepatic Encephalopathy - diagnosis | Adult | Female | Hepatic Encephalopathy - etiology | Aged
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