X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (152) 152
Patent (22) 22
Conference Proceeding (10) 10
Publication (10) 10
Book Chapter (2) 2
Magazine Article (2) 2
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (69) 69
index medicus (52) 52
medical and health sciences (48) 48
medicin och hälsovetenskap (48) 48
male (35) 35
female (30) 30
asthma (29) 29
animals (28) 28
risk factors (23) 23
adult (21) 21
clinical medicine (21) 21
klinisk medicin (21) 21
prevalence (21) 21
lungmedicin och allergi (20) 20
respiratory medicine and allergy (20) 20
biochemistry & molecular biology (19) 19
basic medicine (17) 17
medicinska och farmaceutiska grundvetenskaper (17) 17
research (17) 17
immunology (16) 16
child (15) 15
epidemiology (15) 15
human necessities (14) 14
hygiene (14) 14
medical or veterinary science (14) 14
preparations for medical, dental, or toilet purposes (14) 14
proteins (14) 14
allergy (13) 13
chemistry, medicinal (13) 13
middle aged (13) 13
enzyme inhibitors - pharmacology (12) 12
medicine (12) 12
specific therapeutic activity of chemical compounds ormedicinal preparations (12) 12
cells (11) 11
chemistry (11) 11
physiological aspects (11) 11
structure-activity relationship (11) 11
sweden - epidemiology (11) 11
thermodynamics (11) 11
cancer (10) 10
mice (10) 10
natural sciences (10) 10
naturvetenskap (10) 10
protein binding (10) 10
young adult (10) 10
aged (9) 9
asthma - epidemiology (9) 9
binding sites (9) 9
cohort studies (9) 9
identification (9) 9
molecular sequence data (9) 9
molecular structure (9) 9
multidisciplinary sciences (9) 9
physics (9) 9
skin tests (9) 9
testing (9) 9
adolescent (8) 8
allergies (8) 8
analysis (8) 8
biochemical research methods (8) 8
drug discovery (8) 8
enzyme inhibitors - chemistry (8) 8
health aspects (8) 8
health sciences (8) 8
hälsovetenskaper (8) 8
ligands (8) 8
measuring (8) 8
medicinal chemistry (8) 8
metallurgy (8) 8
models, molecular (8) 8
northern sweden (8) 8
organic chemistry (8) 8
risk-factors (8) 8
stability (8) 8
sweden (8) 8
air pollution (7) 7
base sequence (7) 7
children (7) 7
crystal-structure (7) 7
dna - metabolism (7) 7
double-blind method (7) 7
embedded systems (7) 7
exposure (7) 7
inhibitors (7) 7
läkemedelskemi (7) 7
pyrophosphatases - antagonists & inhibitors (7) 7
questionnaires (7) 7
respiratory symptoms (7) 7
respiratory system (7) 7
air-pollution (6) 6
allergic sensitization (6) 6
amino acid sequence (6) 6
arbetsmedicin och miljömedicin (6) 6
article (6) 6
asthma - immunology (6) 6
biological sciences (6) 6
cell biology (6) 6
cells, cultured (6) 6
cross-over studies (6) 6
gene expression (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Assay and drug development technologies, ISSN 1540-658X, 05/2016, Volume 14, Issue 4, pp. 221 - 225
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 6, pp. 1582 - 1590
Journal Article
Nature Medicine, ISSN 1078-8956, 02/2017, Volume 23, Issue 2, pp. 256 - 263
The cytostatic deoxycytidine analog cytarabine (ara-C) is the most active agent available against acute myelogenous leukemia (AML). Together with... 
MEDICINE, RESEARCH & EXPERIMENTAL | CYTOSINE-ARABINOSIDE | CELLS | ARA-C SENSITIVITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACUTE MYELOID-LEUKEMIA | DRUG-RESISTANCE | CELL BIOLOGY | IN-VITRO | DNA | CHRONIC LYMPHOCYTIC-LEUKEMIA | MUTATIONS | EXPRESSION | Cytarabine - pharmacology | Prognosis | Apoptosis - drug effects | Cytarabine - therapeutic use | Humans | Leukemia, Myeloid, Acute - metabolism | SAM Domain and HD Domain-Containing Protein 1 | Child, Preschool | Infant | Male | Viral Regulatory and Accessory Proteins - pharmacology | Molecular Targeted Therapy | Monomeric GTP-Binding Proteins - drug effects | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Adult | Antimetabolites, Antineoplastic - pharmacology | Female | Child | Disease Models, Animal | Arabinofuranosylcytosine Triphosphate - metabolism | Antimetabolites, Antineoplastic - therapeutic use | Animals | Monomeric GTP-Binding Proteins - metabolism | Adolescent | Aged | Mice | In Vitro Techniques | Cellular proteins | Molecular targeted therapy | Care and treatment | Cytarabine | Patient outcomes | Drug interactions | Innovations | Development and progression | Genetic aspects | Blood diseases | Health aspects | Biomarkers | Cytotoxicity | Chemotherapy | Gene expression | Leukemia | Biological Sciences | Clinical Medicine | Naturvetenskap | Medical and Health Sciences | Hematology | Hematologi | Medicin och hälsovetenskap | Biologiska vetenskaper | Natural Sciences | Klinisk medicin
Journal Article
by Gad, Helge and Gad, Helge and Koolmeister, Tobias and Koolmeister, Tobias and Jemth, Ann-Sofie and Jemth, Ann-Sofie and Eshtad, Saeed and Eshtad, Saeed and Jacques, Sylvain A and Jacques, Sylvain A and Ström, Cecilia E and Ström, Cecilia E and Svensson, Linda M and Svensson, Linda M and Schultz, Niklas and Schultz, Niklas and Lundbäck, Thomas and Lundbäck, Thomas and Einarsdottir, Berglind Osk and Einarsdottir, Berglind Osk and Saleh, Aljona and Saleh, Aljona and Göktürk, Camilla and Göktürk, Camilla and Baranczewski, Pawel and Baranczewski, Pawel and Svensson, Richard and Svensson, Richard and Berntsson, Ronnie P-A and Berntsson, Ronnie P.-A and Gustafsson, Robert and Gustafsson, Robert and Strömberg, Kia and Strömberg, Kia and Sanjiv, Kumar and Sanjiv, Kumar and Jacques-Cordonnier, Marie-Caroline and Jacques-Cordonnier, Marie-Caroline and Desroses, Matthieu and Desroses, Matthieu and Gustavsson, Anna-Lena and Gustavsson, Anna-Lena and Olofsson, Roger and Olofsson, Roger and Johansson, Fredrik and Johansson, Fredrik and Homan, Evert J and Homan, Evert J and Loseva, Olga and Loseva, Olga and Bräutigam, Lars and Bräutigam, Lars and Johansson, Lars and Johansson, Lars and Höglund, Andreas and Höglund, Andreas and Hagenkort, Anna and Hagenkort, Anna and Pham, Therese and Pham, Therese and Altun, Mikael and Altun, Mikael and Gaugaz, Fabienne Z and Gaugaz, Fabienne Z and Vikingsson, Svante and Vikingsson, Svante and Evers, Bastiaan and Evers, Bastiaan and Henriksson, Martin and Henriksson, Martin and Vallin, Karl S A and Vallin, Karl S.A and Wallner, Olov A and Wallner, Olov A and Hammarström, Lars G.J and Hammarström, Lars G J and Wiita, Elisee and Wiita, Elisee and Almlöf, Ingrid and Almlöf, Ingrid and Kalderén, Christina and Kalderén, Christina and Axelsson, Hanna and Axelsson, Hanna and Djureinovic, Tatjana and Djureinovic, Tatjana and Puigvert, Jordi Carreras and Puigvert, Jordi Carreras and Häggblad, Maria and Häggblad, Maria and Jeppsson, Fredrik and Jeppsson, Fredrik and Martens, Ulf and Martens, Ulf and Lundin, Cecilia and Lundin, Cecilia and Lundgren, B and Lundgren, Bo and Granelli, Ingrid and Granelli, Ingrid and ... and Institutionen för medicin och hälsa and Avdelningen för läkemedelsforskning and Linköpings universitet and Hälsouniversitetet
Nature, ISSN 0028-0836, 2014, Volume 508, Issue 7495, pp. 215 - 221
Cancers have dysfunctional redox regulation resulting in reactive oxygen species production, damaging both DNA and free dNTPs. The MTH1 protein sanitizes... 
TARGET | CELLS | OXIDATIVE STRESS | REPAIR | HMTH1 | PROTEIN | MULTIDISCIPLINARY SCIENCES | DNA-SYNTHESIS | MUTAGENIC SUBSTRATE | CELLULAR SENESCENCE | 8-OXOGUANINE | Neoplasms - metabolism | Humans | Molecular Conformation | Male | Molecular Targeted Therapy | Pyrimidines - chemistry | Pyrophosphatases - antagonists & inhibitors | Enzyme Inhibitors - pharmacokinetics | Enzyme Inhibitors - chemistry | DNA Repair Enzymes - metabolism | Oxidation-Reduction - drug effects | Female | Deoxyguanine Nucleotides - metabolism | Cell Death - drug effects | DNA Repair Enzymes - antagonists & inhibitors | DNA Repair Enzymes - chemistry | Phosphoric Monoester Hydrolases - antagonists & inhibitors | Cell Survival - drug effects | Catalytic Domain | Reproducibility of Results | Crystallization | Enzyme Inhibitors - pharmacology | Models, Molecular | Pyrimidines - pharmacology | Nucleotides - metabolism | Enzyme Inhibitors - therapeutic use | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | Pyrimidines - therapeutic use | Pyrimidines - pharmacokinetics | Mice | DNA Damage | Neoplasms - pathology | Phosphoric Monoester Hydrolases - metabolism | Phosphoric Monoester Hydrolases - chemistry | Prevention | Deoxyribonucleotides | DNA damage | Cancer cells | Physiological aspects | Research | Binding proteins | Cancer | Cytotoxicity | Kinases | Cancer therapies | Defects | Proteins | Genotype & phenotype | Mutagenesis | Rodents | Cell cycle | Mutation | Deoxyribonucleic acid--DNA | Tumors | Apoptosis | Index Medicus | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 250 - 14
With a diverse network of substrates, NUDIX hydrolases have emerged as a key family of nucleotide-metabolizing enzymes. NUDT5 (also called NUDIX5) has been... 
POLY(ADP-RIBOSE) | PROTEIN | STABILITY | MULTIDISCIPLINARY SCIENCES | NUDIX HYDROLASES | HYDROLYSIS | VALIDATION | ENGAGEMENT | MECHANISMS | EXPRESSION | INSIGHTS | Cell Proliferation - genetics | Progestins - metabolism | Enzyme Inhibitors - metabolism | Humans | Adenosine Diphosphate Ribose - metabolism | Enzyme Inhibitors - pharmacology | Pyrophosphatases - genetics | Substrate Specificity | Breast Neoplasms - metabolism | Pyrophosphatases - antagonists & inhibitors | Pyrophosphatases - metabolism | Breast Neoplasms - genetics | Cell Nucleus - metabolism | RNA Interference | Signal Transduction - drug effects | Breast Neoplasms - pathology | Adenosine Triphosphate - metabolism | Enzyme Inhibitors - chemistry | Cell Line, Tumor | HL-60 Cells | Female | Cell Proliferation - drug effects | Molecular Structure | Cell Nucleus - drug effects | Cell proliferation | Chromatin | Gene regulation | Sanitation | Breast cancer | Metabolism | Gene expression | ADP | Substrates | Guanine | Chromatin remodeling | Signaling | Inhibitors | Ribose | Progestin | Breast | Adenosine triphosphate | Cancer | Biological Sciences | Medical Biotechnology | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Biologiska vetenskaper | Medicinsk bioteknologi | Natural Sciences | Cellbiologi | Medical Biotechnology (with a focus on Cell Biology (including Stem Cell Biology), Molecular Biology, Microbiology, Biochemistry or Biopharmacy) | Medicinsk bioteknologi (med inriktning mot cellbiologi (inklusive stamcellsbiologi), molekylärbiologi, mikrobiologi, biokemi eller biofarmaci) | Cell Biology
Journal Article
by Busse, William W and Bleecker, Eugene R and Bleecker, Eugene and FitzGerald, J Mark and Ferguson, Gary T and Ferguson, Gary and Barker, Peter and Sproule, Stephanie and Olsson, Richard F and Martin, James and Martin, Ubaldo J and Goldman, Mitchell and Yañez, Anahí and Fernández, Marcelo and Tolcachier, Alberto and Belloni, Juan and Taborda, Jorge and De Salvo, Maria and Maspero, Jorge and Victorio, Carlos and Navarta, Miguel Chirino and Grilli, Monica and Rodríguez, Pablo and Otaola, María and Cambursano, Víctor and Malamud, Patricia and Stok, Ana and Arce, German and Roza, Osiris and Scherbovsky, Fernando and Elias, Pedro and Saez, Maria Salazan and Peters, Matthew and Phillips, Martin and Upham, John and Gibson, Peter and Thien, Francis and Douglass, Jo and Thomas, Paul and Bardin, Philip and Sajkov, Dimitar and Hew, Mark and Langton, David and Pez, Andreia and Fritscher, Carlos and Hetzel, Jorge and Mattos, Waldo and Stelmach, Rafael and Antila, Martti and Fernandes, Ana Luisa and Metev, Hristo and Ivanov, Yavor and Bogdanova, Aneliya and Markova, Ana Dancheva and Peneva, Marinka and Veselinova, Rumyana and Petkova, Tatyana and Petrova, Vanushka and Petrova, Galina and Shopova, Elena and Ivanova, Yuliya and Yotsova, Rumyana and Kirkova, Ginka and Dachev, Svetoslav and Sotirova, Kostadinka and Stoyanova, Mariyana and Yakov, Oleg and Ilieva-Fartunova, Vanya and Lemiere, Catherine and Laviolette, Michel and Yang, William and Pek, Bonavuth and Killorn, William Patrick and Poirier, Claude and Chouinard, Guy and Melenka, Lyle and Leigh, Richard and Nair, Parameswaran and Dorscheid, Delbert and Pavie, Juana and Rosenblut, Andres and Cartagena, Claudia and Quilodran, Carlos and Muñoz, Silvia and Malkusova, Ivana and Veverka, Josef and Holub, Stanislav and Mares, Jaroslav and Kozel, Radovan and Kopecka, Daniela and Zindr, Vladimir and Cerva, Pavel and Chanez, Pascal and Bourdin, Arnaud and Devouassoux, Gilles and Taille, Camille and De Blay, Frédéric and Goupil, Francois and Leroyer, Christophe and Gourcerol, Delphine and ... and BORA Study Investigators and BORA study investigators
The Lancet Respiratory Medicine, ISSN 2213-2600, 01/2019, Volume 7, Issue 1, pp. 46 - 59
Benralizumab is an interleukin-5 receptor α-directed cytolytic monoclonal antibody that has been shown to safely reduce exacerbations and improve lung function... 
BIOMARKERS | ANTIBODY | RECEPTOR | SIROCCO | RESPIRATORY SYSTEM | CRITICAL CARE MEDICINE | Drug therapy | Research | Asthma | Life Sciences | Human health and pathology | Pulmonology and respiratory tract
Journal Article
Nature Communications, ISSN 2041-1723, 03/2016, Volume 7, Issue 1, p. 11040
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2013, Volume 57, Issue 2, pp. 1012 - 1018
Journal Article