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Nature, ISSN 0028-0836, 2014, Volume 512, Issue 1, pp. 78 - 81
Myeloproliferative neoplasms (MPNs) are diseases caused by mutations in the haematopoietic stem cell (HSC) compartment. Most MPN patients have a common... 
TYROSINE KINASE JAK2 | JAK2-V617F | ACTIVATING MUTATION | POLYCYTHEMIA-VERA | BONE | MULTIDISCIPLINARY SCIENCES | Neuroprotective Agents - therapeutic use | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Sympathetic Nervous System - drug effects | Humans | Hematopoietic Stem Cells - pathology | Myeloproliferative Disorders - pathology | Sympathetic Nervous System - physiopathology | Adrenergic beta-3 Receptor Agonists - pharmacology | Neuroprotective Agents - pharmacology | Interleukin-1beta - metabolism | Neoplastic Stem Cells - pathology | Female | Sympathetic Nervous System - pathology | Schwann Cells - drug effects | Hematopoietic Stem Cells - drug effects | Nerve Fibers - pathology | Mesenchymal Stromal Cells - drug effects | Stem Cell Niche | Janus Kinase 2 - genetics | Nerve Fibers - drug effects | Schwann Cells - pathology | Myeloproliferative Disorders - drug therapy | Receptors, Adrenergic, beta-3 - metabolism | Disease Progression | Neoplasms - drug therapy | Nestin - metabolism | Adrenergic beta-3 Receptor Agonists - therapeutic use | Animals | Mice | Mesenchymal Stromal Cells - pathology | Neoplasms - pathology | Complications and side effects | Development and progression | Health aspects | Peripheral nerve diseases | Hematopoietic stem cells | Myeloproliferative disorders | Tumors | Studies | Mutation | Kinases | Rodents | Stem cells | Apoptosis
Journal Article
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1475 - 1475
Abstract Mouse xenografts are routinely used for in vivo studies on human acute myeloid leukemia (AML) cells. However, a significant proportion of primary AML... 
Journal Article
New England Journal of Medicine, ISSN 0028-4793, 03/2018, Volume 378, Issue 10, pp. 924 - 930
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2018, Volume 378, Issue 10, p. 924
Familial erythrocytosis with elevated erythropoietin levels is frequently caused by mutations in genes that regulate oxygen-dependent transcription of the gene... 
CRISPR | Peptides | Hematology | Laboratories | Liver | Cloning | Genes | Values | Genomes | Variance analysis | Hospitals | Hypoxia | Standard deviation | Mutation
Journal Article
Journal of Polymer Science Part A: Polymer Chemistry, ISSN 0887-624X, 12/2015, Volume 53, Issue 23, pp. 2685 - 2692
Journal Article
Pathobiology, ISSN 1015-2008, 06/2019, Volume 86, Issue 2-3, pp. 162 - 166
Background: RUNX1 is a crucial transcription factor for hematological stem cells and well-known for its association with acute lymphoblastic leukemia (ALL) and... 
Novel Insights from Research Practice | CD79a | Acute myelogenous leukemia | PAX5 | Acute lymphoblastic leukemia | RUNX1
Journal Article
Nature Protocols, ISSN 1754-2189, 07/2006, Volume 1, Issue 2, pp. 1001 - 1005
More than a decade ago, it was discovered that cationic peptides could traverse the cellular plasma membrane without specific transporter proteins or membrane... 
PROTEIN | BIOCHEMICAL RESEARCH METHODS | Fluoresceins - chemistry | Cations - chemistry | Peptides - metabolism | Peptides - chemistry | Fluoresceins - metabolism | Cell Membrane Permeability | Fluorometry - methods | Cell Membrane - metabolism | Protein Transport
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2018, Volume 378, Issue 10, pp. 924 - 930
This study shows that mutations that confer loss of function of the full-length messenger RNA of EPO simultaneously confer a gain of function on an alternative... 
POLYCYTHEMIA | MEDICINE, GENERAL & INTERNAL | ERYTHROPOIETIN | GENE | MYELOPROLIFERATIVE NEOPLASMS | TRANSLATION | MAMMALIAN EXPRESSION ATLAS | ERYTHROID PROGENITORS | Genetic aspects | Research | Diagnosis | Erythropoietin | Gene mutations | Polycythemia
Journal Article
The Journal of Gene Medicine, ISSN 1099-498X, 10/2006, Volume 8, Issue 10, pp. 1262 - 1273
Journal Article
Macromolecules, ISSN 0024-9297, 11/2006, Volume 39, Issue 23, pp. 7863 - 7871
The structural flexibility and efficacy of thiourea−amine catalysts for the supramolecular activation and ring-opening polymerization (ROP) of lactide are... 
ORGANOCATALYTIC LIVING POLYMERIZATION | POLYMER SCIENCE | BLOCK-COPOLYMERS | FRAGMENTATION CHAIN TRANSFER | ORGANIC CATALYSTS | FREE-RADICAL POLYMERIZATION | RING-OPENING POLYMERIZATION | N-HETEROCYCLIC CARBENES | BIFUNCTIONAL ORGANOCATALYST | DYNAMIC KINETIC RESOLUTION | RAFT POLYMERIZATION
Journal Article
Journal Article
Journal of Polymer Science Part A: Polymer Chemistry, ISSN 0887-624X, 07/2011, Volume 49, Issue 13, pp. 2990 - 2995
Monodisperse high‐molecular weight macrothiols were synthesized and efficiently coupled to various allylic precursors via thiol–ene click chemistry. A... 
click chemistry | macromonomers | dendrimers; dendritic‐linear hybrids | dendronized polymer | thiols | polyesters | dendrimers; dendritic-linear hybrids | ROUTE | POLYMERS | POLYMER SCIENCE | dendrimers | NETWORKS | dendritic-linear hybrids | STRATEGIES | PROBES | FUNCTIONALIZATION | THERMOSET PROPERTIES | MICROARRAYS | EFFICIENT | Chemistry | Naturvetenskap | Kemi | Natural Sciences | Chemical Sciences
Journal Article