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Trends in Immunology, ISSN 1471-4906, 12/2014, Volume 35, Issue 12, p. 613
* V[delta]1.sup.+ [gamma][delta] T cells engage CD1 molecules using a diverse structural footprint. * The recognition of CD1d-lipid is dominated by the... 
Autoimmunity | T cells | Studies | Antigens | Lymphocytes | Genes | Lipids | Ligands | T cell receptors | Immune system
Journal Article
Science, ISSN 0036-8075, 02/2018, Volume 359, Issue 6377, pp. 770 - 775
Many human cancers are resistant to immunotherapy, for reasons that are poorly understood. We used a genome-scale CRISPR-Cas9 screen to identify mechanisms of... 
IMMUNE-SYSTEM | MELANOMA | MULTIDISCIPLINARY SCIENCES | GENES | ACQUIRED-RESISTANCE | B7 FAMILY | CANCER-IMMUNOTHERAPY | MUTATIONS | ANTITUMOR-ACTIVITY | COMBINATION | BLOCKADE | T-Lymphocytes, Cytotoxic - immunology | Cytotoxicity, Immunologic - genetics | Genetic Testing | Chromosomal Proteins, Non-Histone - metabolism | Skin Neoplasms - immunology | Skin Neoplasms - therapy | Interferon-gamma - therapeutic use | Humans | Melanoma, Experimental - therapy | Transcription Factors - genetics | Bacterial Proteins | Chromosomal Proteins, Non-Histone - genetics | Transcription Factors - metabolism | Animals | Melanoma, Experimental - genetics | Melanoma, Experimental - immunology | Immunotherapy | Skin Neoplasms - genetics | CRISPR-Cas Systems | Endonucleases | HMGB Proteins - genetics | Cell Line, Tumor | HMGB Proteins - metabolism | Mice | Drugs | Toxicity | Genes | Effector cells | Cytotoxicity | Genomes | Lymphocytes T | Remodeling | Inactivation | Immunity | Immunosuppressive agents | Metastases | Lymphocytes | Killing | CRISPR | Deactivation | Cytokines | Secretion | Tumor cells | Melanoma | Gene expression | Patients | Chromatin remodeling | Sensitivity | Inhibitors | Immune checkpoint | SWI/SNF complex | Antitumor activity | Interferon | Mutation | Chemokines | Clear cell-type renal cell carcinoma | Tumors | Cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2013, Volume 110, Issue 19, p. E1771
  Mucosal-associated invariant T (MAIT) cells are an evolutionarily conserved αβ T-cell lineage that express a semi-invariant T-cell receptor (TCR) restricted... 
Proteins | Molecules | Evolution | T cell receptors | Cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 19, pp. 7540 - 7540
Journal Article
Science, ISSN 0036-8075, 03/2018, Volume 359, Issue 6383, pp. 1537 - 1542
MICA and MICB are expressed by many human cancers as a result of cellular stress, and can tag cells for elimination by cytotoxic lymphocytes through natural... 
ACTIVATION | I-RELATED CHAIN | LIGANDS | MULTIDISCIPLINARY SCIENCES | NKG2D RECEPTOR | EXPRESSION | CANCER | CYTOTOXICITY | T-CELLS | CUTTING EDGE | MOLECULES | Humans | Melanoma, Experimental - therapy | Mice, Inbred C57BL | Histocompatibility Antigens Class I - immunology | Melanoma, Experimental - pathology | NK Cell Lectin-Like Receptor Subfamily K - immunology | Antibodies, Monoclonal - therapeutic use | Melanoma - pathology | Receptors, IgG - immunology | Histocompatibility Antigens Class I - chemistry | Neoplasm Metastasis | Animals | Melanoma, Experimental - immunology | Melanoma - immunology | Antibodies, Blocking - immunology | Antibodies, Blocking - therapeutic use | Killer Cells, Natural - immunology | Ligands | Immunocompetence | Mice | Protein Domains - immunology | Melanoma - therapy | Antibodies, Monoclonal - immunology | Health aspects | Killer cells | Genetic aspects | Shedding | Animal models | Lung cancer | Antibodies | Cytotoxicity | Activation | Cell surface | Immunity | Metastases | Proteins | NKG2 antigen | Receptors | Cell activation | Proteolysis | Lymphocytes | Inhibition | Natural killer cells | Immune system | Immunoglobulins | Immunostimulation | Melanoma | Fc receptors | CD16 antigen | Major histocompatibility complex | Lysis | Receptor mechanisms | Cellular stress response | Cancer | Tumors
Journal Article
IMMUNITY, ISSN 1074-7613, 12/2013, Volume 39, Issue 6, pp. 1032 - 1042
The nature of the antigens recognized by gamma delta T cells and their potential recognition of major histocompatibility complex (MHC)-like molecules has... 
NKT CELLS | TCR | MULTIPLE-SCLEROSIS | EPITHELIAL-CELLS | SMALL-INTESTINE | IMMUNOLOGY | CLASS-I MOLECULES | ANTIGEN RECEPTOR | EXPRESSION | CELIAC-DISEASE | LYMPHOCYTES
Journal Article
Journal Article