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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2015, Volume 65, Issue 10, pp. A2085 - A2085
  [...]specific inhibition of Mac-1's adhesive interaction to its biased agonist CD40L by the novel peptide inhibitor cM7 reduced T cell activation, but hardly... 
Cardiovascular | Internal Medicine | Adipose tissues | Obesity | Employee recruitment | Inflammation | Macrophages | Rodents | Metabolic disorders
Journal Article
PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 7, pp. e101446 - 10 p.
Activated protein C (APC) is a serine protease that has both anticoagulant and cytoprotective properties. The cytoprotective effects are protease activated... 
ACTIVATED PROTEIN-C | LIPID-PEROXIDATION | REDUCED ANTICOAGULANT ACTIVITY | MULTIDISCIPLINARY SCIENCES | ENDOTHELIAL-CELLS | MYOCARDIAL-ISCHEMIA | FACTOR-V | THROMBOTIC DISEASE | DEFICIENT MICE | STROKE MODEL | INTERLEUKIN-6 | Endothelial Protein C Receptor | Receptor, PAR-1 - metabolism | Humans | Reperfusion Injury - drug therapy | Interleukin-10 - blood | Male | Protein C - pharmacology | Antigens, CD - metabolism | Interleukin-6 - blood | Cytoprotection - drug effects | HEK293 Cells | Chemokine CCL2 - metabolism | Interleukin-6 - metabolism | Heart - physiopathology | Cell Line | Atherosclerosis - drug therapy | Mice, Inbred C57BL | Receptors, Cell Surface - metabolism | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Chemokine CCL2 - blood | Mice, Knockout | Animals | Myocardial Infarction - drug therapy | Apolipoproteins E - genetics | Mice | Protein C - genetics | Stroke (Disease) | Ischemia | Analysis | Atherosclerosis | Thrombin | Protein C | Inflammation | Heart attack | Myocardial infarction | Animal models | Serine | Proteinase-activated receptor 1 | Myocardial ischemia | Biochemistry | Catalytic activity | Interleukin 6 | Proteins | Reperfusion | Mouse devices | Apolipoprotein E | Proteolysis | Protease | Rodents | Catalysis | Plaques | Recombinant | Cerebral infarction | Anticoagulants | Phenotypes | Stroke | Cytokines | Neutrophils | Activated protein C | Permeability | Signaling | Injury prevention | Arteriosclerosis | Sepsis | Infarction | Serine proteinase | Monocyte chemoattractant protein 1
Journal Article
Blood, ISSN 0006-4971, 2010, Volume 116, Issue 20, pp. 4317 - 4327
Journal Article
Journal of experimental medicine, ISSN 0022-1007, 2010, Volume 207, Issue 2, pp. 391 - 404
Journal Article
European Heart Journal, ISSN 0195-668X, 10/2018, Volume 39, Issue 38, pp. 3521 - 3527
Abstract A large number of cardiovascular events are not prevented by current therapeutic regimens. In search for additional, innovative strategies, immune... 
Cardiovascular disease | Trained immunity | Immune cells | Chronic inflammatory disease | Epigenetic reprogramming | Clinical Review
Journal Article
Circulation, ISSN 0009-7322, 2004, Volume 109, Issue 11, pp. 1408 - 1414
Journal Article
Cardiovascular Research, ISSN 0008-6363, 07/2019, Volume 115, Issue 9, pp. 1385 - 1392
Abstract Inflammation is an important driver of atherosclerosis, and the favourable outcomes of the Canakinumab Anti-inflammatory Thrombosis Outcome Study... 
Journal Article
International Journal of Cardiology, ISSN 0167-5273, 03/2019, Volume 279, pp. 141 - 144
CD40 signalling is involved in chronic inflammation, a condition that plays an important role in non-ischemic heart failure (HF). Small molecule inhibitors of... 
Heart failure | Basic science research | Animal models cardiovascular disease | Inflammation | OBESITY | CARDIAC & CARDIOVASCULAR SYSTEMS | Heart | Medical research | Analysis | Atherosclerosis | Medicine, Experimental | T cells | Macrophages
Journal Article
Journal Article