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Tetrahedron Letters, ISSN 0040-4039, 09/2017, Volume 58, Issue 38, p. 3730
Display Omitted 
Arginine | Glycine
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 09/2018, Volume 59, Issue 38, pp. 3458 - 3460
The CuSO /ascorbate-mediated ‘click’ reaction of 2-(2-azidophenyl)-4,5-diaryloxazoles and arylacetylenes proceeded through an alternate pathway whereby... 
Azides | Nitrenes | Reduction | Amines | Click chemistry | CHEMISTRY | CHEMISTRY, ORGANIC | INHIBITORS | Oxazoles
Journal Article
ARKIVOC, ISSN 1551-7004, 2019, pp. 298 - 306
3-Alkoxy-2-phenylethylisoindolinones are conveniently prepared by reacting the corresponding hydroxylactams with diethylaminosulfur trifluoride (DAST) in the... 
DAST | imides | CATALYZED REDUCTIVE ALKOXYLATION | CHEMISTRY, ORGANIC | INHIBITORS | isoindolinones | iminium ions | ACCESS
Journal Article
Journal of Natural Products, ISSN 0163-3864, 08/2018, Volume 81, Issue 8, pp. 1905 - 1929
Annonacin (1) was isolated from the North American pawpaw (Asimina triloba), as reported earlier from these laboratories. Natural 1 was submitted to the rat... 
OXYGEN SPECIES PRODUCTION | ATYPICAL PARKINSONISM | CHEMISTRY, MEDICINAL | ALZHEIMERS-DISEASE | MEMBRANE-PERMEABILITY ASSAY | BLOOD-BRAIN-BARRIER | DISCOVERY | CELL-DEATH | PLANT SCIENCES | MITOCHONDRIAL COMPLEX-I | UPLC-MS/MS | PHARMACOLOGY & PHARMACY | INHIBITOR
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 11/2016, Volume 81, Issue 21, pp. 10521 - 10526
Journal Article
Synlett, ISSN 0936-5214, 09/2017, Volume 28, Issue 14, pp. 1729 - 1732
Abstract A novel tert -butyl 2-(1-oxoisoindolin-2-yl)acetate derivative is selectively alkylated with propargyl bromide in the presence of lithium... 
cluster | metal complexes | triazoles | click chemistry | peptides | histidine | amino acids | AZIDE-ALKYNE CYCLOADDITION | CATALYSIS | ASYMMETRIC-SYNTHESIS | HYDROGENATION | COMPLEXES | CHEMISTRY, ORGANIC | SCIENCES | ALKYLATIONS | SIDE-CHAINS | SCAFFOLDS
Journal Article
Tetrahedron, ISSN 0040-4020, 07/2017, Volume 73, Issue 29, pp. 4206 - 4213
The synthesis and utilization of all carbon-chain ‘carbocontiguous’ azidoalkynyl precursors for an intramolecular click reaction is described. The substrates... 
Cyclic carbohydrates | Click chemistry | 1,2,3-Triazole | Cyclic peptides | Dipolar cycloaddition | CYCLOADDITION | MACROCYCLES | CHEMISTRY, ORGANIC | Triazoles | cyclic carbohydrates | cyclic peptides | click chemistry | dipolar cycloaddition | 1,2,3-triazole
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 09/2017, Volume 58, Issue 38, pp. 3730 - 3733
The interchangeability of the isoindolinone group as a nitrogen protecting group for amino acid intermediates is demonstrated by the preparation of several... 
Amino acids | Oxidation | Isoindolinones | Protecting groups | Non-proteinogenic | CHEMISTRY | CHEMISTRY, ORGANIC | Protecting Groups
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2012, Volume 53, Issue 42, pp. 5641 - 5644
A series of azidoaryl- and azidoalkyl(diphenyl)oxazole scaffolds were warranted for biofilm inhibition studies. Cyclization of azidoaryl- or azidoalkyl esters... 
Azides | Biofilms | Click chemistry | Oxazoles | Peptidomimetics | Ammonium acetate | Chlorides | Tetrahedrons | Esters | Acetic acid | Scaffolds | Benzoin
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 03/2017, Volume 58, Issue 13, pp. 1280 - 1282
An array of 2-substituted-4,5-diphenyloxazoles were found to be cleaved to triacylamines and diacylamines (imides) using a reagent system composed of... 
Cleavage | Peroxides | Oxazoles | Oxochromium (VI) | Triacylamines | OXIDATION | ROUTE | ENANTIOSELECTIVE SYNTHESIS | CHEMISTRY, ORGANIC | FULLY SUBSTITUTED ALKOXYOXAZOLES | ENDOPEROXIDES | SINGLET MOLECULAR-OXYGEN | RING | TRANSFORMATIONS | Chemical tests and reagents | cleavage | oxazoles | oxochromium (VI) | peroxides | triacylamines
Journal Article
Tetrahedron, ISSN 0040-4020, 10/2016, Volume 72, Issue 40, pp. 6136 - 6141
Click analogues of thalidomide were prepared from 3-azidoglutarimide and a diverse array of arylacetylenes and -ethynyl/ -propargyl phthalimide derivatives.... 
Teratogenesis | Angiogenesis | TNF-α | EM-12 | Multiple myeloma | Thalidomide | Cancer | MULTIPLE-MYELOMA | ACTIVATION | TNF-alpha | ENANTIOMERS | CHEMISTRY, ORGANIC | PHTHALIMIDINE | CYCLOADDITION | ANTIANGIOGENIC ACTIVITY | METABOLISM | CHEMISTRY | DERIVATIVES | Triazoles | Synthesis | Sodium | Phthalimides | Reagents | Coupling | Derivatives | Arrays
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 02/2016, Volume 57, Issue 7, pp. 757 - 759
2-(Halomethyl)-4,5-diphenyloxazoles are effective, reactive scaffolds which can be utilized for synthetic elaboration at the 2-position. Through substitution... 
Heterocycles | Ligands | Click chemistry | Oxaprozin | Oxazoles | REAGENT | HALIDES | ROOM-TEMPERATURE | ALKYL THIOCYANATES | CHEMISTRY, ORGANIC | CONVENIENT | KETONES | NITRILES | CHEMISTRY | MICROWAVE-ASSISTED SYNTHESIS | DERIVATIVES | ligands | click chemistry | oxazoles | heterocycles
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 07/2018, Volume 62, Issue 7
The interaction of the periodontal pathogen Porphyromonas gingivalis with oral streptococci is important for initial colonization of the oral cavity by P.... 
Porphyromonas gingivalis | Periodontitis | Peptidomimetic | STREPTOCOCCUS-GORDONII | DOMAIN | PROTEIN | ORAL STREPTOCOCCI | RECEPTOR | MICROBIOLOGY | peptidomimetic | ADHERENCE | periodontitis | DISEASE | CHEMISTRY | PHARMACOLOGY & PHARMACY | BIOFILM FORMATION
Journal Article
MedChemComm, ISSN 2040-2503, 01/2019, Volume 10, Issue 2, pp. 268 - 279
Several ‘second-generation’ click inhibitors of the multi-species biofilm propagated by the adherence of the oral pathogen Porphyromonas gingivalis to... 
Product inhibition | Keratinocytes | Cytotoxicity | Chemical reactions | Hydrophobicity | Adhesion | Rings (mathematics) | Lipophilic | Biofilms | Inhibitors | Oxazoles | Aromatic compounds | Triazoles | Spacer | Triazine | Set theory | Telomerase | Scaffolds
Journal Article
Letters in Organic Chemistry, ISSN 1570-1786, 11/2015, Volume 12, Issue 9, pp. 622 - 630
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 06/2015, Volume 56, Issue 23, pp. 3039 - 3041
New routes to 2,4,5-trisubstituted oxazoles were established whereby the substitution pattern was established by the structure of the starting nonsymmetrical... 
Azides | Biofilms | Click chemistry | Oxazoles | Peptidomimetics | DIRECT ARYLATION | ACID | ONE-POT SYNTHESIS | CHEMISTRY, ORGANIC | ALCOHOLS | 2,5-DISUBSTITUTED OXAZOLES | CYCLIZATION | AMIDES | Click Chemistry
Journal Article
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