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Current medicinal chemistry, ISSN 0929-8673, 09/2015, Volume 22, Issue 26, pp. 3040 - 3053
Journal Article
Journal Article
Journal Article
Journal Article
Biochemical pharmacology, ISSN 0006-2952, 01/2013, Volume 85, Issue 2, pp. 234 - 244
(a) PAK1 orchestrates mesalamine activity, (b) mesalamine inhibits PAK1; increases membranous E-cadherin and β-catenin; modulates cell adhesion Mesalamine... 
Mesalamine | PAK1 | Beta-catenin | E-cadherin | Cell adhesion | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Cadherins - metabolism | Colonic Neoplasms - prevention & control | Humans | p21-Activated Kinases - antagonists & inhibitors | Male | Neoplasm Proteins - antagonists & inhibitors | Gene Expression Profiling | Neoplasm Proteins - metabolism | Colonic Neoplasms - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | RNA Interference | Intestinal Polyps - prevention & control | Female | Cadherins - genetics | Neoplasm Proteins - genetics | Anticarcinogenic Agents - pharmacology | Anticarcinogenic Agents - therapeutic use | p21-Activated Kinases - genetics | Cell Adhesion - drug effects | Down-Regulation - drug effects | p21-Activated Kinases - metabolism | beta Catenin - metabolism | beta Catenin - genetics | Mesalamine - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Wnt Signaling Pathway - drug effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Colonic Neoplasms - pathology | Intestinal Polyps - pathology | Cell Line, Tumor | Mesalamine - therapeutic use | Mice | Intestinal Polyps - metabolism | Medical colleges | Antifungal agents | Colorectal cancer | Ulcerative colitis | Index Medicus | UC, ulcerative colitis | IBD, inflammatory bowel diseases | CRC, colorectal cancer | PAK1, p21 activated kinase 1 | AJ, adherens junction
Journal Article
Cancer letters, ISSN 0304-3835, 04/2020, Volume 474, pp. 106 - 117
The cancer stem cell (CSC) model defines tumors as hierarchically organized entities, containing a small population of tumorigenic CSC, or tumour-initiating... 
Radioresistance | DNA damage and repair | Tumour-initiating cells | Chemoresistance | Life Sciences & Biomedicine | Oncology | Science & Technology | Index Medicus
Journal Article