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BMC Bioinformatics, ISSN 1471-2105, 2012, Volume 13, Issue 230
BackgroundRoche 454 sequencing is the leading sequencing technology for producing long read high throughput sequence data. Unlike most methods where sequencing... 
Naturvetenskap | Natural Sciences
Journal Article
Nature, ISSN 0028-0836, 05/2013, Volume 497, Issue 7451, pp. 579 - 584
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, pp. e30875 - e30875
The human respiratory tract is heavily exposed to microorganisms. Viral respiratory tract pathogens, like RSV, influenza and rhinoviruses cause major morbidity... 
POLYOMAVIRUS | COMMON COLD | RNA | MULTIDISCIPLINARY SCIENCES | RHINOVIRUS SPECIES C | SAMPLES | VIRUS TTV | SYNCYTIAL VIRUS | IDENTIFICATION | YOUNG-CHILDREN | GENOME | Metagenomics | Picornaviridae - genetics | Humans | Influenza A virus - genetics | Middle Aged | Paramyxoviridae Infections - genetics | Phylogeny | Paramyxoviridae Infections - diagnosis | Respiratory Tract Infections - genetics | Picornaviridae Infections - virology | Young Adult | Metagenome - genetics | Paramyxoviridae Infections - virology | Nasopharynx - virology | Aged, 80 and over | Adult | Influenza, Human - diagnosis | Influenza, Human - virology | Picornaviridae Infections - genetics | Respiratory Tract Infections - virology | Child | Picornaviridae - isolation & purification | Influenza A virus - isolation & purification | Paramyxoviridae - genetics | Picornaviridae Infections - diagnosis | Respiratory Tract Infections - diagnosis | Influenza, Human - genetics | Adolescent | Aged | Paramyxoviridae - isolation & purification | Care and treatment | Diseases | Library collections | Pathogens | Laboratories | Fragments | Science | Viruses | Infections | Genomes | Tissues | Disease control | Patients | Morbidity | Pathogenicity | Respiratory tract | Microorganisms | Disease transmission | Influenza | Respiratory tract diseases | Molecular biology | Bioinformatics | Deoxyribonucleic acid--DNA | Index Medicus | Biological Sciences | Naturvetenskap | Natural Sciences | Bioinformatik och systembiologi | Bioinformatics and Systems Biology | Biologiska vetenskaper | Deoxyribonucleic acid | DNA
Journal Article
BMC Research Notes, ISSN 1756-0500, 2011, Volume 4, Issue 1, pp. 449 - 449
Roche 454 is one of the major 2nd generation sequencing platforms. The particular characteristics of 454 sequence data pose new challenges for bioinformatic... 
Physiological aspects | Research | Nucleotide sequencing | Polymers | Computational biology | Studies | Algorithms | Normal distribution | C plus plus | Titanium | Standard deviation | Random variables | Syntax | Bioinformatics | Manuscripts | Programming languages
Journal Article
Injury Epidemiology, ISSN 2197-1714, 12/2015, Volume 2, Issue 1, pp. 1 - 8
The injury spectrum published in the literature has mainly been presented for a certain age group, as elderly or for a certain type of injury, as fracture and... 
Biostatistics | Public Health | Statistics for Life Sciences, Medicine, Health Sciences | Injury | Statistical Theory and Methods | Contusion | Fracture | Fall | Statistics | Epidemiology | Wound | Strain | Emergency medical care | Injuries
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2015, Volume 10, Issue 12, pp. e0145013 - e0145013
Background The AKT/mTORC1/S6K pathway is frequently overstimulated in breast cancer, constituting a promising therapeutic target. The benefit from mTOR... 
ENDOCRINE RESISTANCE | LOCALIZATION | AMPLIFICATION | MECHANISM | PHOSPHORYLATION | CLONING | PATHWAY | POOR-PROGNOSIS | MULTIDISCIPLINARY SCIENCES | KINASE | GENE LISTS | Humans | RNA, Messenger - genetics | Models, Molecular | Ribosomal Protein S6 Kinases, 70-kDa - genetics | Survival Rate | Gene Expression Profiling | Reverse Transcriptase Polymerase Chain Reaction | Ribosomal Protein S6 Kinases, 90-kDa - chemistry | Ribosomal Protein S6 Kinases, 70-kDa - chemistry | Breast Neoplasms - genetics | TOR Serine-Threonine Kinases - genetics | Breast Neoplasms - pathology | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Breast Neoplasms - mortality | Female | Protein Conformation | Biomarkers, Tumor - genetics | High-Throughput Nucleotide Sequencing | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Breast cancer | Genomes | Health aspects | Analysis | Genomics | TOR protein | Phosphorylation | Insulin-like growth factor I | Genes | Oncology | Homology | AKT protein | Biology | Insulin-like growth factors | Kinases | Cancer therapies | Proteins | Cell growth | Next-generation sequencing | Cell cycle | Trends | Localization | Medical research | Endocrine therapy | siRNA | Gene expression | ErbB-2 protein | Physics | Medicine | Studies | Gene amplification | Inhibitors | Medical prognosis | Breast | Tumors | Cancer | Structural analysis | Index Medicus | Clinical Medicine | Biological Sciences | Naturvetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Kemi | Biologiska vetenskaper | Natural Sciences | Klinisk medicin | Chemical Sciences
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 07/2011, Volume 12, Issue 1, pp. 293 - 293
Background: High throughput pyrosequencing (454 sequencing) is the major sequencing platform for producing long read high throughput data. While most other... 
BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SEQUENCE | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Search Engine | Sequence Alignment - methods | Software | Algorithms | Sequence Analysis, DNA - methods | Usage | Nucleotide sequencing | Applications software | Genetic algorithms | Index Medicus
Journal Article
The European Journal of Health Economics, ISSN 1618-7598, 12/2013, Volume 14, Issue 6, pp. 863 - 873
Objective The objective was to estimate the cost-effectiveness of TNF-inhibitors for the treatment of rheumatoid arthritis in Swedish clinical practice, both... 
Health care costs | Capital costs | Medical practice | Disease models | Utilities costs | Rheumatoid arthritis | Comparators | Biological treatment | Cost analysis | Production costs | Cost-effectiveness analysis | Sweden | Etanercept | Disease progression | Registry data | Anti-TNF | Clinical practice | Retrospective | ANTIBODIES | SOUTHERN SWEDEN | MANAGEMENT | ADALIMUMAB | FOLLOW-UP | HEALTH POLICY & SERVICES | ECONOMICS | QUALITY-OF-LIFE | INFLIXIMAB | ANTAGONISTS | BIOLOGICS REGISTRY | Quality-Adjusted Life Years | Antibodies, Monoclonal, Humanized - therapeutic use | Age Factors | Humans | Immunoglobulin G - therapeutic use | Antibodies, Monoclonal - therapeutic use | Disease Progression | Receptors, Tumor Necrosis Factor - therapeutic use | Antibodies, Monoclonal, Humanized - economics | Infliximab | Arthritis, Rheumatoid - drug therapy | Immunoglobulin G - economics | Cost-Benefit Analysis | Sex Factors | Antirheumatic Agents - economics | Retrospective Studies | Adalimumab | Drug Therapy, Combination | Antibodies, Monoclonal - economics | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Antirheumatic Agents - therapeutic use | Rheumatoid factor | Development and progression | Arthritis | Antirheumatic agents | Tumor necrosis factor | Studies | Economic models | Prescription drugs | Health economics | Economic theory | Medical treatment | Drug therapy | Economic statistics | Health care delivery | Quality of life | Index Medicus | Hälsovetenskap | Medical and Health Sciences | Medicin och hälsovetenskap | Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi | Health Care Service and Management, Health Policy and Services and Health Economy | Health Sciences
Journal Article
Injury epidemiology, ISSN 2197-1714, 12/2016, Volume 3, Issue 1, pp. 22 - 22
To inform targeted prevention, we studied patterns of trauma recidivism and whether a first injury predicts the risk for a recurrent injury. In a... 
Studies | Emergency medical care | Epidemiology | Trauma | Recidivism
Journal Article
Scientific Reports, ISSN 2045-2322, 2018, Volume 8
Massive amounts of metagenomics data are currently being produced, and in all such projects a sizeable fraction of the resulting data shows no or little... 
Biological Sciences | Genome informatics | Naturvetenskap | Biologiska vetenskaper | Natural Sciences | Genetics research | Virology
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 2011, Volume 12, Issue 293
Background: High throughput pyrosequencing (454 sequencing) is the major sequencing platform for producing long read high throughput data. While most other... 
TEKNIKVETENSKAP | Engineering and Technology | Teknik och teknologier | TECHNOLOGY
Journal Article
Journal Article
BMC Research Notes, ISSN 1756-0500, 2011, Volume 4, Issue 449
BackgroundRoche 454 is one of the major 2nd generation sequencing platforms. The particular characteristics of 454 sequence data   pose new challenges for... 
Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
Virus infections impose a huge disease burden on humanity and new viruses are continuously found. As most studies of viral disease are limited to... 
Dissertation
Virology, ISSN 0042-6822, 2012, Volume 432, Issue 2, pp. 427 - 434
Abstract Infections during pregnancy have been suggested to be involved in childhood leukemias. We used high-throughput sequencing to describe the viruses most... 
Infectious Disease | TT virus | High throughput sequencing | Childhood leukemia | INTRAGENOMIC REARRANGEMENT | EBV INFECTION | DNA GENOME | IDENTIFICATION | HODGKINS-DISEASE | PATHOGENICITY | VIROLOGY | RELATEDNESS | ACUTE LYMPHOBLASTIC-LEUKEMIA | GENERATION | Pregnancy Complications, Infectious - virology | Humans | Child, Preschool | Molecular Sequence Data | Phylogeny | Torque teno virus - isolation & purification | Polymerase Chain Reaction | Female | Torque teno virus - genetics | Child | Leukemia - epidemiology | Amino Acid Sequence | Leukemia - virology | Pregnancy Complications, Infectious - epidemiology | DNA Virus Infections - transmission | Infectious Disease Transmission, Vertical | Sequence Analysis, DNA | DNA, Viral - blood | Pregnancy | DNA Virus Infections - epidemiology | Viremia - virology | Viremia - epidemiology | DNA Virus Infections - virology | High-Throughput Nucleotide Sequencing | Torque teno virus - classification | Viremia - transmission | Virus diseases | Virus diseases in pregnancy | Pregnant women | Leukemia | Index Medicus | Infection | Polymerase chain reaction | Primers | Viremia | Genomes | Children | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Natural Sciences | Childhood leukemia; TTvirus; High throughput sequencing | Bioinformatik och systembiologi | Bioinformatics and Systems Biology
Journal Article