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Cell Metabolism, ISSN 1550-4131, 08/2016, Volume 24, Issue 2, pp. 194 - 195
Pro-opiomelanocortin deficiency is a rare cause of severe intractable obesity. Two patients have experienced dramatic weight loss in response to setmelanotide,... 
LEPTIN | HUMANS | OBESITY | MELANOCORTIN-4 RECEPTOR | ENDOCRINOLOGY & METABOLISM | CELL BIOLOGY | Obesity | Receptor, Melanocortin, Type 4 | Pro-Opiomelanocortin - deficiency | Receptors, Melanocortin | Humans | Precision Medicine | Intermedin
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 09/2018, Volume 27, Issue 17, pp. 3099 - 3112
Abstract To explore the genetic determinants of obesity and Type 2 diabetes (T2D), the German Center for Diabetes Research (DZD) conducted crossbreedings of... 
METAANALYSIS | MOUSE GENOME | DIET | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | QTL | PHOSPHOLIPASE A | MICE | TRAITS | IDENTIFICATION | INSULIN SENSITIVITY | METABOLITE PROFILES | Association Studies
Journal Article
International Journal of Molecular Sciences, ISSN 1422-0067, 10/2019, Volume 20, Issue 21, p. 5407
Glucagon’s ability to increase energy expenditure has been known for more than 60 years, yet the mechanisms underlining glucagon’s thermogenic effect still... 
glucagon | fgf21 | brown adipose tissue | energy expenditure | obesity | pharmacology
Journal Article
Obesity, ISSN 1930-7381, 10/2017, Volume 25, Issue 10, pp. 1647 - 1649
Journal Article
Obesity Facts, ISSN 1662-4025, 05/2018, Volume 11, Issue 2, pp. 93 - 108
Objective: We aimed to determine the effect of human SH2B1 variants on leptin and insulin signaling, which are major regulators of energy homeostasis, on the... 
Research Article | Expression genome-wide | STAT | GWAS | JAK | IRS | Locus | SH2B1 | Obesity | Insulin resistance | Mutation | Kinases | Rodents
Journal Article
Diabetologe, ISSN 1860-9716, 03/2019, Volume 15, Issue 2, pp. 177 - 185
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 2019, Volume 29, pp. S1138 - S1138
Journal Article
Der Diabetologe, ISSN 1860-9716, 3/2019, Volume 15, Issue 2, pp. 177 - 185
Glukagon erhöht den Blutzuckerspiegel durch Stimulation der Glukoneogenese und Glykogenolyse. Häufig reduziert auf diese elementare Funktion im... 
Obesity | GLP-1 | Diabetes mellitus | Metabolic Diseases | Proglukagon | General Practice / Family Medicine | Internal Medicine | Angiology | Adipositas | Hyperglycemia | Medicine & Public Health | Diabetes | Hyperglykämie | Endocrinology | Proglucagon
Journal Article
Handbook of Experimental Pharmacology, ISSN 0171-2004, 2015, Volume 233, pp. 437 - 459
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2017, Volume 23, Issue 5, pp. 623 - 630
Journal Article