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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2010, Volume 107, Issue 30, pp. 13426 - 13431
Diabetes mellitus is characterized by either the inability to produce insulin (type 1 diabetes) or as insensitivity to insulin secreted by the body (type 2... 
Beta cells | Hyperglycemia | Diabetes complications | Somatic cells | Induced pluripotent stem cells | Transplantation | Type 2 diabetes mellitus | Insulin | Cellular differentiation | Type 1 diabetes mellitus | Diabetes | Somatic cell programming | Cellular therapy | Stem cells | stem cells | SOMATIC-CELLS | DEFINED FACTORS | ISLETS | MULTIDISCIPLINARY SCIENCES | INDUCTION | cellular therapy | TRANSPLANTATION | THERAPY | MOLECULAR PHYSIOLOGY | somatic cell programming | INSULIN-PRODUCING CELLS | GENERATION | DIFFERENTIATION | diabetes | Glycated Hemoglobin A - analysis | Insulin - analysis | Diabetes Mellitus, Type 1 - surgery | Humans | Hyperglycemia - complications | Green Fluorescent Proteins - genetics | Diabetes Mellitus, Type 1 - complications | Insulin-Secreting Cells - metabolism | Mice, Inbred DBA | Cell Differentiation | Insulin-Secreting Cells - cytology | Induced Pluripotent Stem Cells - cytology | Insulin Secretion | Diabetes Mellitus, Type 2 - complications | Diabetes Mellitus, Type 2 - surgery | Disease Models, Animal | Induced Pluripotent Stem Cells - metabolism | Green Fluorescent Proteins - metabolism | Hyperglycemia - prevention & control | Blood Glucose - analysis | Induced Pluripotent Stem Cells - transplantation | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Insulin - metabolism | Animals | Hyperglycemia - blood | Mice, Nude | Fluorescent Antibody Technique | Mice | Insulin-Secreting Cells - transplantation | Cell Transplantation - methods | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e14062
Background: The cancer stem cell theory hypothesizes that cancers are perpetuated by cancer stem cells (CSC) or tumor initiating cells (TIC) possessing... 
COLON-CANCER | POPULATION | MARKER | MULTIDISCIPLINARY SCIENCES | GROWTH | HYALURONAN | PLURIPOTENCY | FLOW-CYTOMETRY | IDENTIFICATION | CD133(+) | TUMORS | Immunohistochemistry | Humans | Lung Neoplasms - metabolism | Middle Aged | Glycoproteins - metabolism | Peptides - genetics | Immunoblotting | Lung Neoplasms - pathology | Male | Transplantation, Heterologous | Gene Expression Profiling | Antigens, CD - genetics | Antigens, CD - metabolism | Neoplasms, Experimental - pathology | Octamer Transcription Factor-3 - genetics | Flow Cytometry | Peptides - metabolism | Neoplastic Stem Cells - metabolism | Hyaluronan Receptors - metabolism | Neoplasms, Experimental - genetics | Neoplastic Stem Cells - pathology | Female | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Glycoproteins - genetics | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | AC133 Antigen | Hyaluronan Receptors - genetics | Animals | Polycomb Repressive Complex 1 | Mice, Nude | Octamer Transcription Factor-3 - metabolism | Cell Line, Tumor | Aged | Mice | Neoplasms, Experimental - metabolism | Squamous cell carcinoma | Lung cancer, Non-small cell | Analysis | Stem cells | Flow cytometry | Biotechnology | Laboratories | Heart surgery | Oct-4 protein | Lung cancer | Colorectal cancer | Stem cell transplantation | Proteins | Allografts | Epidermal growth factor | CD44 antigen | Xenografts | Cell cycle | CD34 antigen | Subpopulations | Cell survival | Tumor cells | Non-small cell lung carcinoma | Tumor cell lines | Cisplatin | Studies | Polymerase chain reaction | Pathology | Cytometry | Properties (attributes) | Medical prognosis | Biomarkers | In vivo methods and tests | Pluripotency | Tumors | Apoptosis | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 5, p. e10766
Background: SALL4 is a member of the SALL gene family that encodes a group of putative developmental transcription factors. Murine Sall4 plays a critical role... 
SALL1 | GENE | RADIAL RAY SYNDROME | TOWNES-BROCKS-SYNDROME | BIOLOGY | OKIHIRO-SYNDROME | KIDNEY DEVELOPMENT | NANOG | MUTATIONS | RENAL-OCULAR SYNDROME | MURINE HOMOLOG | Multigene Family - genetics | Cell Line | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Pluripotent Stem Cells - cytology | Humans | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Promoter Regions, Genetic - genetics | DNA-Binding Proteins - metabolism | Octamer Transcription Factor-3 - genetics | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Cell Differentiation - genetics | Feedback, Physiological | Animals | Gene Expression Regulation, Developmental | Octamer Transcription Factor-3 - metabolism | Transcription, Genetic | Mice | Models, Genetic | Binding Sites | Genetic aspects | Infants | Genetic transcription | DNA binding proteins | Embryonic stem cells | Patient outcomes | Transcription factors | Laboratories | Leukemia | Genes | Gene regulation | Oct-4 protein | Embryo cells | Stem cell transplantation | Feedback loops | Positive feedback | Cell growth | Feedback | Transgenic animals | Rodents | Transcription activation | Deoxyribonucleic acid--DNA | Cloning | Gene expression | Embryos | Molecular modelling | Womens health | Stem cells | Epigenetics | Control theory | Pluripotency | SALL gene | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 485 - 485
Abstract Introduction The myeloproliferative neoplasms (MPNs), including essential thrombocythemia (ET), are characterized by unregulated hematopoietic stem... 
Journal Article
Journal Article
Combustion Science and Technology, ISSN 0010-2202, 01/2020, pp. 1 - 22
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 50, pp. 19756 - 19761
Embryonic stem cells have potential utility in regenerative medicine because of their pluripotent characteristics. Sall4, a zinc-finger transcription factor,... 
Transcription factors | Somatic cells | Genes | Stem cells | Cell lines | Antibodies | Promoter regions | Gene expression regulation | Embryonic stem cells | Pluripotent stem cells | Oct4 | Sox2 | Epigenetic regulation | Nanog | Induced pluripotent stem cells | DEVELOPMENTAL REGULATORS | MULTIDISCIPLINARY SCIENCES | COMPLEXES | SELF-RENEWAL | GENE SPALT | PROLIFERATION | epigenetic regulation | POLYCOMB | FIBROBLASTS | induced pluripotent stem cells | OKIHIRO-SYNDROME | MUTATIONS | EXPRESSION | Embryonic Stem Cells - metabolism | Epigenesis, Genetic | SOXB1 Transcription Factors - metabolism | DNA-Binding Proteins - metabolism | Octamer Transcription Factor-3 - genetics | DNA Methylation | Chromatin Immunoprecipitation | SOXB1 Transcription Factors - genetics | Gene Expression Regulation, Developmental | Kruppel-Like Transcription Factors - metabolism | Protein Structure, Tertiary | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Pluripotent Stem Cells - physiology | Embryonic Development - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Embryonic Stem Cells - physiology | Pluripotent Stem Cells - metabolism | Transcription Factors - metabolism | Animals | Octamer Transcription Factor-3 - metabolism | Mice | Proto-Oncogene Proteins c-myc - genetics | Genome | Kruppel-Like Transcription Factors - genetics | Epigenetic inheritance | Cellular control mechanisms | Genetic aspects | Genomes | Research | DNA binding proteins | Properties | Biological Sciences
Journal Article
Leukemia, ISSN 0887-6924, 06/2018, Volume 32, Issue 6, pp. 1317 - 1326
Acute myeloid leukemia (AML) bears heterogeneous cells that can consequently offset killing by single-CAR-based therapy, which results in disease relapse.... 
TRIALS | ONCOLOGY | MALIGNANCIES | ALPHA | CHIMERIC ANTIGEN RECEPTOR | HEMATOLOGY | EXPRESSION | CD123 | CD33 | Antigens | Therapy | Animal models | Myeloid leukemia | Toxicity | Leukemia | Stem cell transplantation | Cytotoxicity | Lymphocytes T | Anticancer properties | Antitumor agents | Stem cells | Monoclonal antibodies | CD123 antigen | Biocompatibility | Acute myeloid leukemia
Journal Article
Hepatology, ISSN 0270-9139, 07/2014, Volume 60, Issue 1, pp. 419 - 421
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2881 - 2881
Background CD19 CAR T cell ther