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Cell, ISSN 0092-8674, 08/2013, Volume 154, Issue 3, pp. X484 - 489
Recent reports using single-cell profiling have indicated a remarkably dynamic view of pluripotent stem cell identity. Here, we argue that the pluripotent... 
Journal Article
CELL, ISSN 0092-8674, 06/2019, Volume 177, Issue 7, pp. 1679 - 1681
Baryawno et al. provide a comprehensive atlas of the mouse bone marrow stroma based on single-cell RNA-sequencing data. Their analysis reveals a taxonomy of 17... 
HEMATOPOIETIC STEM-CELL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Analysis | Stem cells | Research institutes
Journal Article
Cell Reports, ISSN 2211-1247, 11/2018, Volume 25, Issue 7, pp. 1772 - 1785.e6
During acute myelosuppression or thrombocytopenia, bone marrow (BM) hematopoietic cells respond rapidly to replenish peripheral blood platelets. While the... 
hematopoietic stem cell | megakaryocyte | thrombopoietin | lineage differentiation | mitochondria | PROGENITORS | MITOCHONDRIAL BIOGENESIS | INFLAMMATION | BONE-MARROW | IN-VIVO | GROWTH | STAT3 | THROMBOCYTOPENIA | EXPRESSION | MEGAKARYOPOIESIS | CELL BIOLOGY
Journal Article
Nature, ISSN 0028-0836, 01/2005, Volume 433, Issue 7021, p. 19
Journal Article
Nature Physics, ISSN 1745-2473, 10/2018, Volume 14, Issue 10, pp. 975 - 976
Mapping cell lineages onto a problem in graph theory suggests that physical principles regulate cell positioning during egg development in the fruit fly -... 
PHYSICS, MULTIDISCIPLINARY | Fruit flies | Graph theory
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2014, Volume 1150, pp. 131 - 139
The potential gains from advances in high-throughput experimental molecular biology techniques are commonly not fully realized since these techniques often... 
Gene expression dynamics | Systems biology | Transcriptome correlation | Data visualization | Network analysis | Computer Graphics | Gene Expression Profiling - methods | Software | Biostatistics - methods | Cluster Analysis | Index Medicus
Journal Article
Cell, ISSN 0092-8674, 08/2013, Volume 154, Issue 3, pp. 484 - 489
Recent reports using single-cell profiling have indicated a remarkably dynamic view of pluripotent stem cell identity. Here, we argue that the pluripotent... 
HETEROGENEITY | VARIABILITY | SINGLE-CELL | GROUND-STATE PLURIPOTENCY | BIOCHEMISTRY & MOLECULAR BIOLOGY | EMBRYONIC STEM-CELLS | BIOLOGY | NANOG | NOISE | ES CELLS | TRANSCRIPTOME ANALYSIS | CELL BIOLOGY | Pluripotent Stem Cells - metabolism | Gene Expression | Mice | Statistics as Topic | Animals | Pluripotent Stem Cells - cytology | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 08/2010, Volume 466, Issue 7308, pp. 829 - 834
The cellular constituents forming the haematopoietic stem cell (HSC) niche in the bone marrow are unclear, with studies implicating osteoblasts, endothelial... 
PROGENITOR CELLS | OSTEOBLAST | OSTEOPONTIN | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | SELF-RENEWAL | RECEPTOR | DIFFERENTIATION | NEURAL CREST | COOPERATION | EXPRESSION | Chondrocytes - cytology | Nestin | Multipotent Stem Cells - metabolism | Parathyroid Hormone - pharmacology | Cell Lineage - drug effects | Chondrocytes - drug effects | Mesenchymal Stromal Cells - cytology | Multipotent Stem Cells - drug effects | Sympathetic Nervous System - physiology | Cell Division | Stromal Cells - drug effects | Osteoblasts - cytology | Hematopoietic Stem Cells - drug effects | Mesenchymal Stromal Cells - drug effects | Gene Expression Regulation - genetics | Osteoblasts - drug effects | Stromal Cells - metabolism | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Mice, Transgenic | Hematopoietic Stem Cells - metabolism | Stem Cell Niche - cytology | Nerve Tissue Proteins - metabolism | Granulocyte Colony-Stimulating Factor - pharmacology | Animals | Chemokine CXCL12 - metabolism | Cell Differentiation - drug effects | Multipotent Stem Cells - cytology | Hematopoietic Stem Cells - cytology | Stem Cell Niche - metabolism | Mice | Stem Cell Niche - drug effects | Osteoblasts - metabolism | Intermediate Filament Proteins - metabolism | Mesenchymal Stem Cell Transplantation | Stromal Cells - cytology | Cell Movement | Physiological aspects | Genetic aspects | Research | Bone marrow cells | Gene expression | Osteoblasts | Hematopoietic stem cells | Studies | Proteins | Bone marrow | Rodents | Stem cells | Index Medicus
Journal Article
[Rinsho ketsueki] The Japanese journal of clinical hematology, ISSN 0485-1439, 2017, Volume 58, Issue 8, p. 942
Repeated cell divisions induce DNA damage accumulation, which impairs stem cell function during aging. However, the general molecular mechanisms by which this... 
DNA-Binding Proteins - metabolism | Animals | Cellular Senescence | Humans | Aging | Hematopoietic Stem Cells - metabolism | Telomere - metabolism | DNA Damage | DNA-Binding Proteins - genetics | Telomere - genetics
Journal Article
2012, 1. Aufl., ISBN 9789400743298, 203
The rapidly developing field of systems biology is influencing many aspects of biological research and is expected to transform biomedicine. Some emerging... 
Systems biology | Medicine: General Issues | Biotechnology | Gene Expression | Biomedicine | Proteomics | Systems Biology | Biomedicine general | Cell Biology | Network analysis (Planning)
eBook
FRONTIERS IN GENETICS, ISSN 1664-8021, 01/2019, Volume 10, pp. 2 - 2
The molecular regulatory network underlying stem cell pluripotency has been intensively studied, and we now have a reliable ensemble model for the "average"... 
EPIBLAST | ACTIVATION | regulatory network | GROUND-STATE | pluripotency stem cells | FACE RECOGNITION | single-cell data | SELF-RENEWAL | PRIMITIVE ENDODERM | PLURIPOTENCY | TRANSITION | HETEROGENEITY | stem cell | eigenface approach | GENETICS & HEREDITY | DIFFERENTIATION | machine learning (artificial intelligence) | Usage | Research | Genetic regulation | Machine learning | Stem cells
Journal Article