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Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A16242 - A16242
IntroductionInflammation reduction with the interleukin (IL)-1β inhibitor canakinumab significantly reduces the first major adverse cardiovascular event in... 
Journal Article
European heart journal, ISSN 0195-668X, 09/2019
The Canakinumab Antiinflammatory Thrombosis Outcomes Study (CANTOS) established that targeting inflammation with interleukin-1β (IL-1β) inhibition can... 
Journal Article
American Heart Journal, ISSN 0002-8703, 2013, Volume 165, Issue 6, pp. 1008 - 1014
Background Carriers of the rs4363657C and rs4149056C alleles in SLCO1B1 have increased myopathic complaints when taking simvastatin. Whether rosuvastatin has a... 
Journal Article
Annals of internal medicine, ISSN 0003-4819, 10/2018, Volume 169, Issue 8, pp. 535 - 542
Although studies have shown that interleukin-1β (IL-1β) inhibitors can shorten gout attacks, whether they can prevent gout attacks is unclear. To examine the... 
Journal Article
Annals of Internal Medicine, ISSN 0003-4819, 10/2018, Volume 169, Issue 8, p. 535
Background: Although studies have shown that interleukin-1[beta] (IL-1[beta]) inhibitors can shorten gout attacks, whether they can prevent gout attacks is... 
Prevention | Clinical trials | Interleukin-1 | Research | Analysis | Gout
Journal Article
CLINICAL CHEMISTRY, ISSN 0009-9147, 05/2012, Volume 58, Issue 5, pp. 877 - 886
BACKGROUND: Although lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) levels are associated with cardiovascular events Lp-PLA(2) is physically linked to... 
C-REACTIVE PROTEIN | BIOMARKERS | MORTALITY | MEN | CARDIOVASCULAR-DISEASE | ATHEROSCLEROSIS | RISK | PRAVASTATIN | MEDICAL LABORATORY TECHNOLOGY | CORONARY-HEART-DISEASE | ROSUVASTATIN | Proteolipids | Lipoproteins | Immunotherapy | Physiological aspects | Cholesterol, LDL | Phospholipases | Research | Blood lipoproteins | Health aspects
Journal Article
Lancet, The, ISSN 0140-6736, 2012, Volume 380, Issue 9841, pp. 565 - 571
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2017, Volume 377, Issue 12, pp. 1119 - 1131
Patients with myocardial infarction and a high-sensitivity CRP level of 2 mg or more per liter were assigned to one of three canakinumab doses or placebo. The... 
C-REACTIVE PROTEIN | MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | MYOCARDIAL-INFARCTION | STATIN THERAPY | CLONAL HEMATOPOIESIS | INFLAMMATION | CARDIOVASCULAR-DISEASE | INTERLEUKIN-1-BETA INHIBITION | RISK | CORONARY-ARTERY-DISEASE | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Secondary Prevention | Infection - etiology | Incidence | Dose-Response Relationship, Drug | Anti-Inflammatory Agents - adverse effects | C-Reactive Protein - metabolism | Lipids - blood | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Anti-Inflammatory Agents - administration & dosage | Female | Neutropenia - chemically induced | Interleukin-1beta - antagonists & inhibitors | Stroke - prevention & control | Atherosclerosis - drug therapy | Double-Blind Method | Interleukin-1beta - immunology | Atherosclerosis - blood | Myocardial Infarction - drug therapy | Antibodies, Monoclonal - administration & dosage | Aged | Myocardial Infarction - prevention & control | Myocardial infarction | Cerebral infarction | Stroke | Heart attacks | C-reactive protein | Cytokines | Clinical trials | Cardiovascular disease | Innate immunity | Inflammation | Angina | Angina pectoris | Thrombosis | Cholesterol | Disease prevention | Proteins | Arteriosclerosis | Atherosclerosis | Cardiovascular diseases | Health risk assessment | Drug therapy | Drug dosages | Klinisk medicin | Clinical Medicine
Journal Article