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1. Sharing cities
: a case for truly smart and sustainable cities
by McLaren, Duncan, 1965 and Agyeman, Julian, author
2015, Urban and industrial environments, ISBN 9780262029728, x, 445
Urban economics | Sharing | Urbanization | Municipal government | Sustainable urban development | Technological innovations | Social aspects | Environmental | Public Policy | SCIENCE | City Planning & Urban Development | Environmental Science (see also Chemistry | POLITICAL SCIENCE | Sharing - Social aspects
Book
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2. The new visual neurosciences
by Werner, John Simon editor of compilation and Chalupa, Leo M. editor of compilation
2014, The MIT Press, ISBN 9780262019163, xiii, 1675 pages
Visual cortex | Neurosciences | Vision | Visual pathways
Book
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3. Full Text CRISPR-Cas9 DNA Base-Editing and Prime-Editing
by Kantor, Ariel and McClements, Michelle E and MacLaren, Robert E
International journal of molecular sciences, ISSN 1422-0067, 09/2020, Volume 21, Issue 17, p. 6240
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Tropism | CRISPR | Enzymes | DNA damage | Adenine | Insertion | Editing | Transversion | Genomes | Gene deletion | Double-strand break repair | Proteins | Toolkits | Engineering | Immunogenicity | Efficiency | Editors | Serotypes | Cytosine | Mutation | Gene therapy | Molecular biology | Deoxyribonucleic acid--DNA | Index Medicus | gene therapy | CRISPR/Cas9 | genome engineering | prime-editing | base-editing | adeno-associated vector
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4. Hard choices, soft law
: voluntary standards in global trade, environment, and social governance
by Kirton, John J and Trebilcock, Michael J., 1941
2004, Global environmental governance series, ISBN 0754609669, xviii, 372
International trade | International agencies | International cooperation | Standardization | Commercial policy | Environmental aspects | Social responsibility of business | Social aspects | Sustainable development | Public-private sector cooperation | Environmental Policy | International Trade (incl. trade agreements & tariffs) | Global Governance | International Law - Law
Book
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5. Full Text CRISPR Interference-Potential Application in Retinal Disease
by Peddle, Caroline F and Fry, Lewis E and McClements, Michelle E and MacLaren, Robert E
International journal of molecular sciences, ISSN 1422-0067, 04/2020, Volume 21, Issue 7, p. 2329
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Transcription factors | Transcription | Clinical trials | Amino acids | Retina | Genomes | Transplantation | Proteins | Gene disruption | DNA methylation | Deoxyribonucleic acid--DNA | CRISPR | RNA-mediated interference | Interference | RNA polymerase | Ribonucleic acid--RNA | Gene expression | Gene silencing | In vivo methods and tests | Genetic engineering | Mutation | Disruption | Gene therapy | Binding sites | Inhibitory postsynaptic potentials | Index Medicus | gene therapy | RNAi | CRISPR interference | CRISPRi | CRISPR/Cas9 | knock-down
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6. Full Text Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial
by MacLaren, Robert E, Prof and Groppe, Markus, PhD and Barnard, Alun R, PhD and Cottriall, Charles L, PhD and Tolmachova, Tanya, PhD and Seymour, Len, Prof and Clark, K Reed, PhD and During, Matthew J, Prof and Cremers, Frans P M, Prof and Black, Graeme C M, Prof and Lotery, Andrew J, Prof and Downes, Susan M, FRCOphth and Webster, Andrew R, Prof and Seabra, Miguel C, Prof
The Lancet (British edition), ISSN 0140-6736, 2014, Volume 383, Issue 9923, pp. 1129 - 1137
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Ophthalmology | Retinopathies | Choroideremia - physiopathology | Gene Transfer Techniques | Genetic Vectors - administration & dosage | Retinal Detachment - therapy | Humans | Middle Aged | Transgenes - genetics | Fluorescence | Male | Adaptor Proteins, Signal Transducing - genetics | Retinal Detachment - physiopathology | Adenoviridae - genetics | Adult | Aged | Choroideremia - therapy | Visual Acuity - physiology | Injections, Intraocular | Adaptor Proteins, Signal Transducing - administration & dosage | Genetic Therapy - methods | Care and treatment | Gene therapy | Patient outcomes | Choroideremia | Methods | Macular degeneration | Aging | Retina | Index Medicus | Abridged Index Medicus
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7. Full Text A 2020 vision of ocular gene therapy
by MacLaren, Robert E
Gene therapy, ISSN 0969-7128, 06/2020
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Genetics & Heredity | Biotechnology & Applied Microbiology | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Index Medicus
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8. Full Text Function of human pluripotent stem cell-derived photoreceptor progenitors in blind mice
by Barnea-Cramer, Alona O and Wang, Wei and Lu, Shi-Jiang and Singh, Mandeep S and Luo, Chenmei and Huo, Hongguang and McClements, Michelle E and Barnard, Alun R and MacLaren, Robert E and Lanza, Robert
Scientific reports, ISSN 2045-2322, 07/2016, Volume 6, Issue 1, pp. 29784 - 29784
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Induced Pluripotent Stem Cells - pathology | Human Embryonic Stem Cells - metabolism | Blindness - metabolism | Humans | Blindness - pathology | Retinitis Pigmentosa - metabolism | Human Embryonic Stem Cells - pathology | Photoreceptor Cells, Vertebrate - transplantation | Animals | Heterografts | Retinitis Pigmentosa - therapy | Cell Differentiation | Mice | Blindness - therapy | Photoreceptor Cells, Vertebrate - metabolism | Photoreceptor Cells, Vertebrate - pathology | Retinitis Pigmentosa - pathology | Induced Pluripotent Stem Cells - metabolism | Index Medicus
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9. Full Text Benefits of gene therapy for both eyes
by MacLaren, Robert E
The Lancet (British edition), ISSN 0140-6736, 2016, Volume 388, Issue 10045, pp. 635 - 636
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Genetic Therapy | Genetic Vectors | Visual Acuity | Humans | Genetic research | Gene therapy | Retina | Genomes | Congenital diseases | Blindness | Index Medicus | Abridged Index Medicus
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10. Full Text The Location of Exon 4 Mutations in RP1 Raises Challenges for Genetic Counseling and Gene Therapy
by Nanda, Anika and McClements, Michelle E and Clouston, Penny and Shanks, Morag E and MacLaren, Robert E
American journal of ophthalmology, ISSN 0002-9394, 06/2019, Volume 202, pp. 23 - 29
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Genetic Testing | Microtubule-Associated Proteins - genetics | Exons | Microtubule-Associated Proteins - metabolism | Humans | Middle Aged | Genetic Counseling - methods | Retinitis Pigmentosa - genetics | Male | Retinitis Pigmentosa - diagnosis | DNA - genetics | Phenotype | Retinitis Pigmentosa - therapy | DNA Mutational Analysis | Pedigree | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Mutation | Genetic Therapy - methods | Medical research | Genes | Amino acids | Genetic screening | Proteins | Genetic counseling | Hospitals | Medical genetics | Genetic research | Medicine, Experimental | Genetic aspects | Nucleotide sequencing | Gene therapy | DNA sequencing | Medical imaging | Family medical history | Patients | Consultants | Custom design | Tomography | Photoreceptors | Genetic engineering | Age | Index Medicus | Abridged Index Medicus
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11. Full Text Analysis of Early Cone Dysfunction in an In Vivo Model of Rod-Cone Dystrophy
by Hassall, Mark M and McClements, Michelle E and Barnard, Alun R and Patricio, Maria and Aslam, Sher A and Maclaren, Robert E
International journal of molecular sciences, ISSN 1422-0067, 09/2020, Volume 21, Issue 17, p. 6055
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Retinitis pigmentosa | Retina | Gene expression | Phototransduction | Cones | Retinal degeneration | Photoreceptors | Retinitis | In vivo methods and tests | Degeneration | Mutation | Dystrophy | Supplementation | Gene therapy | Apoptosis | Index Medicus | retinitis pigmentosa | rod-cone dystrophy | gene therapy | cone photoreceptors | retina
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12. Full Text AAV Induced Expression of Human Rod and Cone Opsin in Bipolar Cells of a Mouse Model of Retinal Degeneration
by McClements, Michelle E and Staurenghi, Federica and Visel, Meike and Flannery, John G and MacLaren, Robert E and Cehajic-Kapetanovic, Jasmina
BioMed research international, ISSN 2314-6133, 2/2021, Volume 2021, pp. 1 - 8
Enzymes | Rhodopsin | Retinal cells | Clinical trials | Recovery of function | Visual signals | Retina | Vectors (Biology) | Success | Visual perception | Proteins | Capsids | Toolkits | Opsins | Vision | Bipolar cells | Information processing | Signal processing | Retinal degeneration | Photoreceptors | Degeneration | Supplementation | Gene therapy
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13. Full Text Gene therapy for age-related macular degeneration
by MacLaren, Robert E
The Lancet (British edition), ISSN 0140-6736, 2015, Volume 386, Issue 10011, pp. 2369 - 2370
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Wet Macular Degeneration - therapy | Female | Male | Vascular Endothelial Growth Factor Receptor-1 - administration & dosage | Humans | Genetic Therapy - methods | Macular degeneration | Physiological aspects | Care and treatment | Gene therapy | Proteins | Cytomegalovirus | Clinical trials | Kinases | Gene expression | Age | Index Medicus | Abridged Index Medicus
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