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by Seddon, Alistair W. R and Mackay, Anson W and Baker, Ambroise G and Birks, H. John B and Breman, Elinor and Buck, Caitlin E and Ellis, Erle C and Froyd, Cynthia A and Gill, Jacquelyn L and Gillson, Lindsey and Johnson, Edward A and Jones, Vivienne J and Juggins, Stephen and Macias‐Fauria, Marc and Mills, Keely and Morris, Jesse L and Nogués‐Bravo, David and Punyasena, Surangi W and Roland, Thomas P and Tanentzap, Andrew J and Willis, Kathy J and Aberhan, Martin and Asperen, Eline N and Austin, William E. N and Battarbee, Rick W and Bhagwat, Shonil and Belanger, Christina L and Bennett, Keith D and Birks, Hilary H and Bronk Ramsey, Christopher and Brooks, Stephen J and Bruyn, Mark and Butler, Paul G and Chambers, Frank M and Clarke, Stewart J and Davies, Althea L and Dearing, John A and Ezard, Thomas H. G and Feurdean, Angelica and Flower, Roger J and Gell, Peter and Hausmann, Sonja and Hogan, Erika J and Hopkins, Melanie J and Jeffers, Elizabeth S and Korhola, Atte A and Marchant, Robert and Kiefer, Thorsten and Lamentowicz, Mariusz and Larocque‐Tobler, Isabelle and López‐Merino, Lourdes and Liow, Lee H and McGowan, Suzanne and Miller, Joshua H and Montoya, Encarni and Morton, Oliver and Nogué, Sandra and Onoufriou, Chloe and Boush, Lisa P and Rodriguez‐Sanchez, Francisco and Rose, Neil L and Sayer, Carl D and Shaw, Helen E and Payne, Richard and Simpson, Gavin and Sohar, Kadri and Whitehouse, Nicki J and Williams, John W and Witkowski, Andrzej and McGlone, Matt
Journal of Ecology, ISSN 0022-0477, 01/2014, Volume 102, Issue 1, pp. 256 - 267
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2009, Volume 360, Issue 4, pp. 354 - 362
The antiplatelet drug clopidogrel requires activation by cytochrome P-450 (CYP) enzymes. This study shows that CYP polymorphisms that reduce clopidogrel... 
VARIABILITY | MEDICINE, GENERAL & INTERNAL | PERCUTANEOUS CORONARY INTERVENTION | PHARMACOKINETICS | STENT THROMBOSIS | INCREASED RISK | PLATELET INHIBITION | PRASUGREL | PHARMACODYNAMICS | INDIVIDUAL RESPONSIVENESS | ATHEROTHROMBOTIC EVENTS | Ticlopidine - pharmacology | Ticlopidine - therapeutic use | Area Under Curve | Humans | Aryl Hydrocarbon Hydroxylases - genetics | Male | Cardiovascular Diseases - genetics | Angioplasty, Balloon, Coronary | Ticlopidine - adverse effects | Ticlopidine - metabolism | Cardiovascular Diseases - epidemiology | Platelet Aggregation Inhibitors - pharmacology | Adult | Female | Platelet Aggregation - drug effects | Platelet Aggregation Inhibitors - metabolism | Platelet Aggregation Inhibitors - therapeutic use | Stents | Platelet Aggregation Inhibitors - adverse effects | Genotype | Thrombosis - epidemiology | Combined Modality Therapy | Ticlopidine - analogs & derivatives | Polymorphism, Genetic | Randomized Controlled Trials as Topic | Cytochrome P-450 CYP2C19 | Acute Coronary Syndrome - therapy | Heterozygote | Thrombosis - genetics | Mutation | Usage | Genetic variation | Cytochrome P-450 | Physiological aspects | Causes of | Clopidogrel | Cardiovascular diseases | Health aspects | Risk factors | Studies | Cardiovascular disease | Heart attacks | Drug therapy | Index Medicus | Abridged Index Medicus
Journal Article
by Estrada Gil, Karol and Styrkarsdottir, Unnur and Evangelou, Evangelos and Hsu, Yi-Hsiang and Duncan, Emma and Ntzani, Evangelia and Oei, Ling and Albagha, Omar M and Amin, Najaf and Kemp, John and Koller, Daniel and Li, Guo and Liu, Ching-Ti and Minster, Ryan and Moayyeri, Alireza and Vandenput, Liesbeth and Willner, Dana and Xiao, Su-Mei and Yerges-Armstrong, Laura and Zheng, Hou-Feng and Alonso, Nerea and Eriksson, Joel and Kammerer, Candace and Kaptoge, Stephen and Leo, Paul and Thorleifsson, Gudmar and Wilson, Scott and Wilson, James and Aalto, Ville and Alen, Theo and Aragaki, Aaron and Aspelund, Thor and Center, Jacqueline and Dailiana, Zoe and Duggan, C and Garcia, Melissa and Garcia-Giralt, Natàlia and Giroux, Sylvie and Hallmans, Göran and Hocking, Lynne and Husted, Lise Bjerre and Jameson, Karen and Khusainova, Rita and Kim, Ghi Su and Kooperberg, Charles and Koromila, Theodora and Kruk, Marcin and Laaksonen, Marika and LaCroix, Anea and Lee, Seung and Leung, Ping and Lewis, Joshua and Masi, Laura and Mencej-Beac, Simona and Nguyen, Tuan and Nogues, Xavier and Patel, Millan and Prezelj, Janez and Rose, Lynda and Scollen, Serena and Siggeirsdottir, Kristin and Smith, Davey and Svensson, Olle and Trompet, Stella and Trummer, Olivia and Schoor, Natasja and Woo, Margaret M and Zhu, Kun and Balcells, Susana and Brandi, M.L and Buckley, Brendan M and Cheng, Sulin and Christiansen, C and Cooper, Charles and Dedoussis, George and Ford, Ian and Frost, Morten and Goltzman, David and González-Macías, Jesús and Kähönen, Mika and Karlsson, Magnus and Khusnutdinova, Elza and Koh, Jung-Min and Kollia, Panagoula and Langdahl, Bente and Leslie, William and Lips, Paul and Ljunggren, Östen and Lorenc, Roman and Marc, Janja and Mellström, Dan and Obermayer-Pietsch, Barbara and Olmos, David and Pettersson-Kymmer, Ulrika and Reid, David and Riancho, José and Ridker, Paul and Rousseau, Francois and Lagboom, P Eline and Tang, Nelson L and ... and Medicinska fakulteten and Umeå universitet and Institutionen för folkhälsa och klinisk medicin and Institutionen för farmakologi och klinisk neurovetenskap and Klinisk farmakologi and Näringsforskning and Institutionen för kirurgisk och perioperativ vetenskap
Nature Genetics, ISSN 1061-4036, 05/2012, Volume 44, Issue 5, pp. 491 - 501
textabstractBone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and... 
WOMEN | GENE | VARIANTS | DISEASE | GENETICS & HEREDITY | OSTEOPOROTIC FRACTURES | LRP5 | PATTERNS | EXPRESSION | BURDEN | HIP | Glycoproteins - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Low Density Lipoprotein Receptor-Related Protein-5 - genetics | Extracellular Matrix Proteins - genetics | Humans | Risk Factors | Computational Biology | Intercellular Signaling Peptides and Proteins - genetics | European Continental Ancestry Group | Genotype | Male | Bone Density - genetics | Gene Expression Profiling | Phosphoproteins - genetics | Fractures, Bone - genetics | Mitochondrial Membrane Transport Proteins - genetics | Polymorphism, Single Nucleotide - genetics | Female | Femur Neck - physiopathology | Osteoporosis - genetics | Spectrin - genetics | Quantitative Trait Loci | Lumbar Vertebrae - physiopathology | Quantitative trait loci | Measurement | Fractures | Bones | Genetic aspects | Identification and classification | Density | Risk factors | Medical research | Osteoporosis | Genomics | Bone density | Gene loci | Vèrtebres lumbars | Gens | Femur | Genes | Bone densitometry | Densitometria òssia | Fèmur | Lumbar vertebrae | Basic Medicine | Medical Genetics | Medicinsk genetik | ortopedi | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | genetik | Genetics | Orthopaedics
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2018, Volume 128, Issue 7, pp. 3041 - 3052
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 03/2016, Volume 374, Issue 13, pp. 1243 - 1252
Journal Article
by Oei, Ling and Hsu, Yi-Hsiang and Styrkarsdottir, Unnur and Eussen, Bert H and de Klein, Annelies and Peters, Marjolein J and Halldorsson, Bjarni and Liu, Ching-Ti and Alonso, Nerea and Kaptoge, Stephen K and Thorleifsson, Gudmar and Hallmans, Göran and Hocking, Lynne J and Husted, Lise Bjerre and Jameson, Karen A and Kruk, Marcin and Lewis, Joshua R and Patel, Millan S and Scollen, Serena and Svensson, Olle and Trompet, Stella and van Schoor, Natasja M and Zhu, Kun and Buckley, Brendan M and Cooper, Cyrus and Ford, Ian and Goltzman, David and González-Macías, Jesús and Langdahl, Bente Lomholt and Leslie, William D and Lips, Paul and Lorenc, Roman S and Olmos, José M and Pettersson-Kymmer, Ulrika and Reid, David M and Riancho, José A and Slagboom, P Eline and Garcia-Ibarbia, Carmen and Ingvarsson, Thorvaldur and Johannsdottir, Hrefna and Luben, Robert and Medina-Gómez, Carolina and Arp, Pascal and Nandakumar, Kannabiran and Palsson, Stefan Th and Sigurdsson, Gunnar and van Meurs, Joyce B J and Zhou, Yanhua and Hofman, Albert and Jukema, J Wouter and Pols, Huibert A P and Prince, Richard L and Cupples, L Adrienne and Marshall, Christian R and Pinto, Dalila and Sato, Daisuke and Scherer, Stephen W and Reeve, Jonathan and Thorsteinsdottir, Unnur and Karasik, David and Richards, J Brent and Stefansson, Kari and Uitterlinden, André G and Ralston, Stuart H and Ioannidis, John P A and Kiel, Douglas P and Rivadeneira, Fernando and Estrada, Karol and Medicinska fakulteten and Umeå universitet and Institutionen för folkhälsa och klinisk medicin and Institutionen för farmakologi och klinisk neurovetenskap and Ortopedi and Klinisk farmakologi and Enheten för biobanksforskning and Näringsforskning and Institutionen för kirurgisk och perioperativ vetenskap
Journal of Medical Genetics, ISSN 0022-2593, 02/2014, Volume 51, Issue 2, pp. 122 - 131
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 02/2017, Volume 376, Issue 7, pp. 652 - 662
Journal Article