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1. Full Text Reply to “Mitochondrial DNA deletions discriminate affected from unaffected LRRK 2 mutation carriers”
by Bakshi, Rachit and Macklin, Eric A and Schwarzschild, Michael A
Annals of Neurology, ISSN 0364-5134, 08/2019, Volume 86, Issue 2, pp. 326 - 327
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2. Full Text Reply to “Mitochondrial DNA deletions discriminate affected from unaffected LRRK2 mutation carriers”
by Bakshi, Rachit and Macklin, Eric A and Schwarzschild, Michael A
Annals of Neurology, ISSN 0364-5134, 08/2019, Volume 86, Issue 2, pp. 326 - 327
Mitochondrial DNA | Mutation | LRRK2 protein | Deoxyribonucleic acid--DNA
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3. Full Text Sulforaphane treatment of autism spectrum disorder (ASD)
by Kanwaljit Singh and Susan L. Connors and Eric A. Macklin and Kirby D. Smith and Jed W. Fahey and Paul Talalay and Andrew W. Zimmerman
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 43, pp. 15550 - 15555
Autism spectrum disorder (ASD), characterized by both impaired communication and social interaction, and by Stereotypie behavior, affects about 1 in 68,... 
Acute stress disorders | Oxidative stress | Broccoli | Autistic disorder | Atrial heart septal defects | Sprouts | Social interaction | Pervasive child development disorders | Placebos | Fever | ACTIVATION | CLINICAL-TRIAL | BROCCOLI | ENZYMES | CHINA | MULTIDISCIPLINARY SCIENCES | CHEMOPREVENTION | STRESS | CANCER | CHILDREN | Young Adult | Isothiocyanates - therapeutic use | Social Behavior | Humans | Adolescent | Adult | Male | Treatment Outcome | Child Development Disorders, Pervasive - drug therapy | Isothiocyanates - adverse effects | Care and treatment | Usage | Phytochemicals | Pervasive developmental disorders | Dosage and administration | Health aspects | Organosulfur compounds | Biological Sciences
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4. Full Text An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study
by Miller, Timothy M, Dr and Pestronk, Alan, Prof and David, William, MD and Rothstein, Jeffrey, Prof and Simpson, Ericka, MD and Appel, Stanley H, Prof and Andres, Patricia L, MS and Mahoney, Katy, BA and Allred, Peggy, DPT and Alexander, Katie, BA and Ostrow, Lyle W, MD and Schoenfeld, David, Prof and Macklin, Eric A, PhD and Norris, Daniel A, PhD and Manousakis, Georgios, MD and Crisp, Matthew, BS and Smith, Richard, MD and Bennett, C Frank, PhD and Bishop, Kathie M, PhD and Cudkowicz, Merit E, Prof
Lancet Neurology, The, ISSN 1474-4422, 2013, Volume 12, Issue 5, pp. 435 - 442
Summary Background Mutations in SOD1 cause 13% of familial amyotrophic lateral sclerosis. In the SOD1 Gly93Ala rat model of amyotrophic lateral sclerosis, the... 
Neurology | WILD-TYPE | THERAPIES | SUPEROXIDE-DISMUTASE | CLINICAL NEUROLOGY | DISEASE | Injections, Spinal | Superoxide Dismutase - genetics | Double-Blind Method | Oligodeoxyribonucleotides, Antisense - administration & dosage | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Oligodeoxyribonucleotides, Antisense - therapeutic use | Male | Treatment Outcome | Amyotrophic Lateral Sclerosis - drug therapy | Adult | Female | Superoxide Dismutase-1 | Amyotrophic lateral sclerosis | Genetic aspects | RNA | Analysis | Index Medicus
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5. Full Text Randomized multicenter investigation of folate plus vitamin B 12 supplementation in schizophrenia
by Roffman, Joshua L and Lamberti, J. Steven and Achtyes, Eric and Macklin, Eric A and Galendez, Gail C and Raeke, Lisa H and Silverstein, Noah J and Smoller, Jordan W and Hill, Michele and Goff, Donald C
JAMA Psychiatry, ISSN 2168-622X, 2013, Volume 70, Issue 5, pp. 481 - 489
Importance: More effective treatments are needed for negative symptoms of schizophrenia, which are typically chronic, disabling, and costly. Negative symptoms... 
METHYLENETETRAHYDROFOLATE REDUCTASE | FOLIC-ACID FORTIFICATION | HOMOCYSTEINE LEVELS | CONTROLLED-TRIAL | CATECHOL-O-METHYLTRANSFERASE | RISK-FACTOR | MYOCARDIAL-INFARCTION | NEGATIVE SYMPTOMS | PSYCHIATRY | PLASMA HOMOCYSTEINE | VASCULAR-DISEASE
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6. Full Text Virtual mind-body treatment for geographically diverse youth with neurofibromatosis: A pilot randomized controlled trial
by Lester, Ethan and DiStefano, Sofia and Mace, Ryan and Macklin, Eric A and Plotkin, Scott and Vranceanu, Ana-Maria
General Hospital Psychiatry, ISSN 0163-8343, 12/2019
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7. Full Text Reply to "Mitochondrial DNA deletions discriminate affected from unaffected LRRK2 mutation carriers"
by Bakshi, R and Macklin, EA and Schwarzschild, MA
ANNALS OF NEUROLOGY, ISSN 0364-5134, 08/2019, Volume 86, Issue 2, pp. 326 - 327
NEUROSCIENCES | DAMAGE | CLINICAL NEUROLOGY
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8. Full Text Mind-body therapy via videoconferencing in patients with neurofibromatosis
by Vranceanu, Ana-Maria and Riklin, Eric and Merker, Vanessa L and Macklin, Eric A and Park, Elyse R and Plotkin, Scott R
Neurology, ISSN 0028-3878, 08/2016, Volume 87, Issue 8, pp. 806 - 814
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9. Full Text Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial
by Wills, Anne-Marie, Dr and Hubbard, Jane, RD and Macklin, Eric A, PhD and Glass, Jonathan, Prof and Tandan, Rup, Prof and Simpson, Ericka P, MD and Brooks, Benjamin, Prof and Gelinas, Deborah, MD and Mitsumoto, Hiroshi, Prof and Mozaffar, Tahseen, Prof and Hanes, Gregory P, MD and Ladha, Shafeeq S, MD and Heiman-Patterson, Terry, Prof and Katz, Jonathan, MD and Lou, Jau-Shin, MD and Mahoney, Katy, BA and Grasso, Daniela, BA and Lawson, Robert, BS and Yu, Hong, MS and Cudkowicz, Merit, Prof and MDA Clinical Res Network and MDA Clinical Research Network
Lancet, The, ISSN 0140-6736, 2014, Volume 383, Issue 9934, pp. 2065 - 2072
Summary Background Amyotrophic lateral sclerosis is a fatal neurodegenerative disease with few therapeutic options. Mild obesity is associated with greater... 
Internal Medicine | SURVIVAL | MEDICINE, GENERAL & INTERNAL | BENEFIT | ENERGY-EXPENDITURE | MANAGEMENT | PREDICTOR | NEUROLOGY | BODY-MASS INDEX | DEATH | ALS PATIENTS | DYSLIPIDEMIA | Enteral Nutrition - methods | Double-Blind Method | Amyotrophic Lateral Sclerosis - therapy | Cholesterol - blood | Humans | Middle Aged | Kaplan-Meier Estimate | Diet, High-Fat - adverse effects | Male | Amyotrophic Lateral Sclerosis - blood | Energy Intake | Enteral Nutrition - adverse effects | Pilot Projects | Adult | Female | Aged | Diet, High-Fat - methods | Amyotrophic lateral sclerosis | Diet therapy | Research | Health aspects | Tube feeding | Enteral feeding | Clinical trials | Care and treatment | Analysis | Nutrition research | Carbohydrates | Diet | Mortality | Metabolism
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10. Full Text Complications of β-thalassemia major in North America
by Cunningham, Melody J and Macklin, Eric A and Neufeld, Ellis J and Cohen, Alan R and Thalassemia Clinical Res Network and Thalassemia Clinical Research Network and the Thalassemia Clinical Research Network
Blood, ISSN 0006-4971, 07/2004, Volume 104, Issue 1, pp. 34 - 39
Treatment of patients with beta-thalassemia major has improved dramatically during the past 40 years; however, the current clinical status of these patients... 
SURVIVAL | CLEARANCE | VIRUS | DEFEROXAMINE | MANAGEMENT | DISEASE | DISORDERS | HEPATITIS-C VIREMIA | COOLEYS-ANEMIA | HEMATOLOGY | IRON-CHELATING THERAPY | Liver - pathology | beta-Thalassemia - epidemiology | Age Factors | Humans | Middle Aged | Child, Preschool | Endocrine System Diseases - etiology | Infant | beta-Thalassemia - complications | Deferoxamine - adverse effects | Liver Cirrhosis - epidemiology | Ferritins - blood | Heart Diseases - epidemiology | Adult | Retrospective Studies | Child | beta-Thalassemia - blood | Liver Cirrhosis - etiology | Iron Chelating Agents - therapeutic use | beta-Thalassemia - therapy | Cross-Sectional Studies | Genotype | Iron - metabolism | Liver - chemistry | Endocrine System Diseases - epidemiology | Iron Chelating Agents - adverse effects | Transfusion Reaction | Heart Diseases - etiology | Iron Overload - epidemiology | Adolescent
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11. Full Text Higher urate in LRRK2 mutation carriers resistant to Parkinson disease
by Bakshi, Rachit and Macklin, Eric A and Logan, Robert and Zorlu, Musab M and Xia, Ning and Crotty, Grace F and Zhang, Ellen and Chen, Xiqun and Ascherio, Alberto and Schwarzschild, Michael A
Annals of Neurology, ISSN 0364-5134, 04/2019, Volume 85, Issue 4, pp. 593 - 599
Objective LRRK2 mutations, the most common genetic cause of Parkinson disease (PD), display incomplete penetrance, indicating the importance of other genetic... 
PENETRANCE | G2019S | RISK | SEX-DIFFERENCES | NEUROSCIENCES | CLINICAL NEUROLOGY | Parkinson's disease | Neurodegenerative diseases | Pathogenesis | Parkinsons disease | Sex | Regression analysis | Uric acid | Risk analysis | Risk factors | Carriers | Consortia | Antioxidants | Men | Biomarkers | Sampling methods | Hormone replacement therapy | Mutation | LRRK2 protein | Movement disorders
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12. Full Text Cultivating resiliency in patients with neurofibromatosis 2 who are deafened or have severe hearing loss: a live‑video randomized control trial
by Greenberg, Jonathan and Carter, Sarah and Lester, Ethan and Funes, Christopher J and Macklin, Eric A and Plotkin, Scott and Vranceanu, Ana-Maria
Journal of Neuro-Oncology, ISSN 0167-594X, 12/2019, Volume 145, Issue 3, pp. 561 - 569
Patients with NF2 who are deaf or have significant hearing loss face numerous and unique challenges which lead to poor quality of life, and thus may benefit... 
Mind–body program | Neurology | Medicine & Public Health | Neurofibromatosis | Deaf | Videoconferencing | Oncology | Resiliency | Communication access real-time translation
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13. Full Text Factors Associated with "DSM-5" Severity Level Ratings for Autism Spectrum Disorder
by Mazurek, Micah O and Lu, Frances and Macklin, Eric A and Handen, Benjamin L
Autism: The International Journal of Research and Practice, ISSN 1362-3613, 02/2019, Volume 23, Issue 2, p. 468
The newest edition of the "Diagnostic and Statistical Manual of Mental Disorders" (5th ed., DSM-5) introduced substantial changes to the diagnostic criteria... 
Intelligence Quotient | Diagnostic Tests | Age Differences | Severity (of Disability) | Emotional Problems | Autism | Interpersonal Communication | Behavior Problems | Pervasive Developmental Disorders | Observation | Children | Adolescents | Clinical Diagnosis | Symptoms (Individual Disorders)
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14. Full Text The revised El Escorial criteria “clinically probable laboratory supported ALS”—once a promising now a superfluous category?
by Braun, Nathalie and Macklin, Eric A and Sinani, Ervin and Sherman, Alexander and Weber, Markus and the Pooled Resource Open-Access ALS Clinical Trials Consortium
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, ISSN 2167-8421, 09/2019, pp. 1 - 5
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15. Full Text Mind–body therapy via videoconferencing in patients with neurofibromatosis: An RCT
by Vranceanu, Ana-Maria and Riklin, Eric and Merker, Vanessa L and Macklin, Eric A and Park, Elyse R and Plotkin, Scott R
Neurology, ISSN 0028-3878, 08/2016, Volume 87, Issue 8, pp. 806 - 814
OBJECTIVE:To test, within a single-blind randomized controlled trial, the feasibility, acceptability, efficacy, and durability of a mind–body program (the... 
Single-Blind Method | Follow-Up Studies | Outcome Assessment (Health Care) | Psychotherapy, Group - methods | Humans | Middle Aged | Male | Neurofibromatoses - complications | Feasibility Studies | Depression - etiology | Anxiety - therapy | Mind-Body Therapies - methods | Patient Acceptance of Health Care | Telemedicine - methods | Quality of Life | Videoconferencing | Adult | Female | Depression - therapy | Anxiety - etiology | Neurofibromatoses - therapy
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16. Full Text Factors associated with DSM-5 severity level ratings for autism spectrum disorder
by Mazurek, Micah O and Lu, Frances and Macklin, Eric A and Handen, Benjamin L
Autism, ISSN 1362-3613, 2/2019, Volume 23, Issue 2, pp. 468 - 476
The newest edition of the Diagnostic and Statistical Manual of Mental Disorders (5th ed., DSM-5) introduced substantial changes to the diagnostic criteria for... 
diagnosis | DSM-5 | need for support | autism spectrum disorder | severity level | CRITERIA | PSYCHOLOGY, DEVELOPMENTAL | DIAGNOSTIC OBSERVATION SCHEDULE | Emotional-Behavioural problems | Intelligence | Mental disorders | Decision making | Severity | Diagnostic and Statistical Manual | Stereotypes | Autistic children | Autism | Intelligence tests | Repetitive behaviour | Cognitive functioning | Ratings & rankings | Behavior | Stereotyped behaviour | Behavioural problems
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17. Full Text The impact of a mind–body program on multiple dimensions of resiliency among geographically diverse patients with neurofibromatosis
by Zale, Emily L and Zale, Emily L and Pierre-Louis, Catherine and Pierre-Louis, Catherine and Macklin, Eric A and Macklin, Eric A and Riklin, Eric and Riklin, Eric and Vranceanu, Ana-Maria and Vranceanu, Ana-Maria
Journal of Neuro-Oncology, ISSN 0167-594X, 4/2018, Volume 137, Issue 2, pp. 321 - 329
The neurofibromatoses (NF) are incurable genetic disorders that can cause nerve sheath tumors, chronic pain, and disfiguration. Patients with NF report lower... 
Intervention | Neurology | Medicine & Public Health | Neurofibromatosis | Oncology | Resiliency | Coping | Mindfulness | SCHWANNOMATOSIS | RELAXATION RESPONSE | CLINICAL NEUROLOGY | PILOT | ONCOLOGY | PSYCHOLOGICAL RESILIENCE | SOCIAL SUPPORT | QUALITY-OF-LIFE | STRESS | COPING STRATEGIES | HEALTH OUTCOMES | Medical colleges | Mindfulness meditation | Chronic pain | Social interactions | Pain | Attention | Quality of life | Tumors | Social support
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18. Full Text Prospective relationship of duration of untreated psychosis to psychopathology and functional outcome over 12years
by Hill, Michele and Crumlish, Niall and Clarke, Mary and Whitty, Peter and Owens, Elizabeth and Renwick, Laoise and Browne, Stephen and Macklin, Eric A and Kinsella, Anthony and Larkin, Conall and Waddington, John L and O'Callaghan, Eadbhard
Schizophrenia Research, ISSN 0920-9964, 11/2012, Volume 141, Issue 2-3, pp. 215 - 221
The duration of untreated psychosis is well recognised as an independent predictor of symptomatic and functional outcome in the short term and has facilitated... 
First-episode | Follow-up
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19. Full Text Urate and neuroprotection trials
by Schwarzschild, Michael A and Macklin, Eric A and Ascherio, Alberto and Parkinson Study Grp SURE-PD Invest and Parkinson Study Group SURE-PD Investigators
Lancet Neurology, The, ISSN 1474-4422, 2014, Volume 13, Issue 8, pp. 758 - 758
  In the URICO-ICTUS stroke study, Chamorro and colleagues presented a predefined subgroup analysis of urate effects that showed an increased likelihood of an... 
Neurology | SERUM | URIC-ACID | CLINICAL NEUROLOGY | PARKINSON DISEASE | Female | Male | Antioxidants - therapeutic use | Stroke - drug therapy | Uric Acid - therapeutic use | Humans | Womens health | Parkinsons disease | Men
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20. Full Text Oral Inosine Persistently Elevates Plasma antioxidant capacity in Parkinson's disease
: Inosine Elevates Antioxidant Capacity
by Bhattacharyya, Shamik and Bakshi, Rachit and Logan, Robert and Ascherio, Alberto and Macklin, Eric A and Schwarzschild, Michael A
Movement Disorders, ISSN 0885-3185, 03/2016, Volume 31, Issue 3, pp. 417 - 421
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