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Nature Protocols, ISSN 1754-2189, 08/2010, Volume 5, Issue 8, pp. 1470 - 1479
Limbal stem cells (LSCs) have an important role in the maintenance of the corneal surface epithelium, and autologous cultured limbal epithelial cell... 
STEM-CELLS | RECONSTRUCTION | BIOCHEMICAL RESEARCH METHODS | OCULAR SURFACE DISEASE | CORNEAL EPITHELIUM | HUMAN AMNIOTIC MEMBRANE | DIFFERENTIATION | EQUIVALENTS | AUTOLOGOUS SERUM | EX-VIVO | TRANSPLANTATION | Amnion | Cell Culture Techniques | Culture Media | Epithelium, Corneal - cytology | Humans | Physiological aspects | Cornea | Research | Epithelial cells
Journal Article
Tissue Engineering Part A, ISSN 1937-3341, 02/2014, Volume 20, Issue 3-4, pp. 646 - 655
Extensive damage to the limbal region of the cornea leads to a severe form of corneal blindness termed as limbal stem cell deficiency (LSCD). Whereas most... 
Original Articles
Journal Article
Journal Article
Journal Article
Journal of Biosciences, ISSN 0250-5991, 3/2013, Volume 38, Issue 1, pp. 123 - 134
Millions of people world over suffer visual disability due to retinal dystrophies which can be age-related or a genetic disorder resulting in gradual... 
Life Sciences | Life Sciences, general | Microbiology | mouse embryonic fibroblasts (MEFs) | Zoology | retinal pigmented epithelium (RPE) | Plant Sciences | Biomedicine general | Cell Biology | Induced pluripotent stem cells (iPSCs) | SYSTEM | MOUSE | INDUCTION | TRANSPLANTATION | VISUAL FUNCTION | BIOLOGY | HUMAN FIBROBLASTS | GENERATION | EFFICIENT | PHOTORECEPTORS | Retinal Pigment Epithelium - metabolism | Epithelial Cells - metabolism | Epigenesis, Genetic | SOXB1 Transcription Factors - metabolism | Embryoid Bodies - metabolism | Octamer Transcription Factor-3 - genetics | DNA Methylation | Embryoid Bodies - cytology | Retroviridae - genetics | SOXB1 Transcription Factors - genetics | Gene Expression Regulation, Developmental | Kruppel-Like Transcription Factors - metabolism | Cell Differentiation | Eye Proteins - genetics | Epithelial Cells - cytology | Induced Pluripotent Stem Cells - cytology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Biomarkers - metabolism | Promoter Regions, Genetic | Proto-Oncogene Proteins c-myc - metabolism | Animals | Eye Proteins - metabolism | Octamer Transcription Factor-3 - metabolism | Fibroblasts - cytology | Mice | Proto-Oncogene Proteins c-myc - genetics | Primary Cell Culture | Genetic Vectors | Kruppel-Like Transcription Factors - genetics | Retinal Pigment Epithelium - cytology | Stem cell research | Tracers (Biology) | Methylation | Embryonic stem cells | Analysis | Retina | Eye diseases | Gene expression | Rodents | Stem cells
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 06/2013, Volume 131, Issue 6, pp. 731 - 736
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 05/2008, Volume 325, Issue 2, pp. 588 - 594
G protein-coupled P2Y receptors (P2Y-R) are activated by adenine and uracil nucleotides. The P2Y(14) receptor (P2Y(14)-R) is activated by at least four... 
Animals | Transfection | Humans | Receptors, Purinergic P2 - genetics | Cercopithecus aethiops | Purinergic P2 Receptor Antagonists | Rats | Receptors, Purinergic P2Y | Purinergic P2 Receptor Agonists | Uridine Diphosphate - metabolism | COS Cells
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 2006, Volume 69, Issue 6, pp. 2068 - 2075
Journal Article
JAMA Ophthalmology, ISSN 2168-6165, 06/2013, Volume 131, Issue 6, p. 731
  Although several reports are available on the use of conventional and cultured limbal epithelium using various substrates in the treatment of limbal stem... 
Transplants & implants | Medical treatment | Stem cells | Eye diseases | Children & youth
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2005, Volume 48, Issue 26, pp. 8108 - 8111
Combining molecular dynamics (MD) in a hydrated phospholipids (DOPC) bilayer, Monte Carlo search, and synthesis of locked nucleotide analogues we discovered... 
Journal Article
STEM CELLS Translational Medicine, ISSN 2157-6564, 11/2014, Volume 3, Issue 11, pp. 1331 - 1341
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 05/2008, Volume 47, Issue 5, pp. 326 - 337
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2006, Volume 49, Issue 18, pp. 5532 - 5543
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 02/2006, Volume 71, Issue 4, pp. 540 - 549
With the long-term goal of developing receptor subtype-selective high affinity agonists for the uracil nucleotide-activated P2Y receptors we have carried out a... 
G protein-coupled receptor | Pyrimidines | Structure activity relationship | Homology modeling | Nucleotides | Phospholipase C
Journal Article
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