X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (30) 30
humans (22) 22
animals (17) 17
lipids (17) 17
biochemistry & molecular biology (16) 16
inflammation (16) 16
male (14) 14
cell biology (10) 10
female (9) 9
mice (9) 9
enzymes (8) 8
article (7) 7
research (7) 7
adult (6) 6
arachidonate 12-lipoxygenase - metabolism (6) 6
chemistry (6) 6
expression (6) 6
oxidation-reduction (6) 6
physiological aspects (6) 6
rodents (6) 6
signal transduction (6) 6
arachidonic-acid (5) 5
enzyme inhibitors - pharmacology (5) 5
ligands (5) 5
lipidomics (5) 5
metabolites (5) 5
nf-kappa b - metabolism (5) 5
oncology (5) 5
resolution (5) 5
aerosol (4) 4
arachidonic acid - metabolism (4) 4
cell line, tumor (4) 4
cyclooxygenase (4) 4
docosahexaenoic acid (4) 4
eicosanoid (4) 4
eicosanoids (4) 4
eicosanoids - metabolism (4) 4
endothelium (4) 4
fatty acids - metabolism (4) 4
lc-ms (4) 4
lipid metabolism - physiology (4) 4
mass spectrometry (4) 4
medicine (4) 4
mice, inbred c57bl (4) 4
multidisciplinary sciences (4) 4
nebulizer (4) 4
omega-3 fatty acids (4) 4
physiology (4) 4
platelet-type 12-lipoxygenase (4) 4
pregnancy (4) 4
prostaglandin-endoperoxide synthases - metabolism (4) 4
prostaglandins (4) 4
proteins (4) 4
rats (4) 4
science (4) 4
sheep (4) 4
12-hydroxy-5,8,10,14-eicosatetraenoic acid - metabolism (3) 3
12-lipoxygenase (3) 3
amniotic fluid - metabolism (3) 3
analysis (3) 3
arachidonic acid (3) 3
biology (3) 3
biosynthesis (3) 3
carcinoma-cells (3) 3
cardiovascular system (3) 3
cells (3) 3
chromatography, high pressure liquid (3) 3
development and progression (3) 3
diabetes (3) 3
dosage and administration (3) 3
eicosapentaenoic acid (3) 3
epoxy fatty acids (3) 3
epoxyeicosatrienoic acids (3) 3
exercise (3) 3
fatty acids (3) 3
fatty acids, unsaturated - metabolism (3) 3
gene expression (3) 3
gene-expression (3) 3
genetic aspects (3) 3
health aspects (3) 3
homeostasis (3) 3
kinase (3) 3
lipid mediators (3) 3
lipid metabolism (3) 3
lipoxygenase (3) 3
melanoma-cells (3) 3
metabolism (3) 3
nf-kappa b (3) 3
oxidative stress (3) 3
pathway (3) 3
phosphatases (3) 3
phosphorylation (3) 3
polyunsaturated fatty-acids (3) 3
prostate cancer (3) 3
research article (3) 3
seminal vesicles - enzymology (3) 3
signal transduction - drug effects (3) 3
stroke (3) 3
supplementation (3) 3
time factors (3) 3
more...
Library Location Library Location
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Hepatology, ISSN 0270-9139, 04/2012, Volume 55, Issue 4, pp. 1070 - 1082
Journal Article
Journal Article
by Bowden, John A and Heckert, Alan and Ulmer, Candice Z and Jones, Christina M and Koelmel, Jeremy P and Abdullah, Laila and Ahonen, Linda and Alnouti, Yazen and Armando, Aaron M and Asara, John M and Bamba, Takeshi and Barr, John R and Bergquist, Jonas and Borchers, Christoph H and Brandsma, Joost and Breitkopf, Susanne B and Cajka, Tomas and Cazenave-Gassiot, Amaury and Checa, Antonio and Cinel, Michelle A and Colas, Romain A and Cremers, Serge and Dennis, Edward A and Evans, James E and Fauland, Alexander and Fiehn, Oliver and Gardner, Michael S and Garrett, Timothy J and Gotlinger, Katherine H and Han, Jun and Huang, Yingying and Neo, Aveline Huipeng and Hyötyläinen, Tuulia and Izumi, Yoshihiro and Jiang, Hongfeng and Jiang, Houli and Jiang, Jiang and Kachman, Maureen and Kiyonami, Reiko and Klavins, Kristaps and Klose, Christian and Köfeler, Harald C and Kolmert, Johan and Koal, Therese and Koster, Grielof and Kuklenyik, Zsuzsanna and Kurland, Irwin J and Leadley, Michael and Lin, Karen and Maddipati, Krishna Rao and McDougall, Danielle and Meikle, Peter J and Mellett, Natalie A and Monnin, Cian and Moseley, M. Arthur and Nandakumar, Renu and Oresic, Matej and Patterson, Rainey and Peake, David and Pierce, Jason S and Post, Martin and Postle, Anthony D and Pugh, Rebecca and Qiu, Yunping and Quehenberger, Oswald and Ramrup, Parsram and Rees, Jon and Rembiesa, Barbara and Reynaud, Denis and Roth, Mary R and Sales, Susanne and Schuhmann, Kai and Schwartzman, Michal Laniado and Serhan, Charles N and Shevchenko, Andrej and Somerville, Stephen E and St John-Williams, Lisa and Surma, Michal A and Takeda, Hiroaki and Thakare, Rhishikesh and Thompson, J. Will and Torta, Federico and Triebl, Alexander and Trötzmüller, Martin and Ubhayasekera, S. J. Kumari and Vuckovic, Dajana and Weir, Jacquelyn M and Welti, Ruth and Wenk, Markus R and Wheelock, Craig E and Yao, Libin and Yuan, Min and Zhao, Xueqing Heather and Zhou, Senlin and Teknisk-naturvetenskapliga vetenskapsområdet and Uppsala universitet and Analytisk kemi and Institutionen för kemi - BMC and Kemiska sektionen
Journal of Lipid Research, ISSN 0022-2275, 2017, Volume 58, Issue 12, pp. 2275 - 2288
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e57254
The purpose of the current study was to evaluate the effect of 12/15-lipoxygenase (12/15-LOX) metabolites on retinal endothelial cell (REC) barrier function.... 
DIABETIC-RETINOPATHY | OXIDATIVE STRESS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | KINASE | ANGIOTENSIN-II | GROWTH-FACTOR | ADHESION MOLECULES | VASCULAR NAD(P)H OXIDASE | EXPRESSION | PROTEIN-TYROSINE-PHOSPHATASE | Retina - drug effects | Diabetic Retinopathy - drug therapy | Retina - metabolism | Reactive Oxygen Species - metabolism | Arachidonate 12-Lipoxygenase - metabolism | Gene Expression - drug effects | Membrane Glycoproteins - metabolism | NADPH Oxidases - metabolism | Diabetic Retinopathy - pathology | Vascular Endothelial Growth Factor Receptor-2 - genetics | Dextrans | Hydroxyeicosatetraenoic Acids - pharmacology | NADPH Oxidases - genetics | Vascular Endothelial Growth Factor Receptor-2 - agonists | Biological Transport - drug effects | Zonula Occludens-1 Protein - metabolism | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid - pharmacology | Zonula Occludens-1 Protein - genetics | Endothelial Cells - metabolism | Flavanones - pharmacology | Enzyme Inhibitors - pharmacology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Fluorescein-5-isothiocyanate - analogs & derivatives | Mice, Transgenic | Electric Impedance | Arachidonate 15-Lipoxygenase - metabolism | NADPH Oxidase 2 | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - genetics | Diabetic Retinopathy - metabolism | Diabetic Retinopathy - genetics | Membrane Glycoproteins - genetics | Animals | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - metabolism | Signal Transduction - drug effects | Cell Membrane Permeability - drug effects | Protein Tyrosine Phosphatase, Non-Receptor Type 6 - antagonists & inhibitors | Mice | Endothelial Cells - pathology | Retina - pathology | Endothelial Cells - drug effects | Oxidases | Dextran | Phosphatases | Metabolites | Permeability | Vascular endothelial growth factor | Monomolecular films | Endothelium | Multiplexing | Health sciences | Diabetic retinopathy | Immunoassay | Reactive oxygen species | Vascular cell adhesion molecule 1 | Oxidase | Retina | Biology | Kinases | Phosphatase | NAD(P)H oxidase | Interleukin 6 | Proteins | Hyperglycemia | Cell growth | Rodents | CYBB protein | Age | Tyrosine | Intercellular adhesion molecule 1 | Diabetes mellitus | Inflammation | Dentistry | Fatty acids | Zonula occludens-1 protein | Substrates | Endothelial cells | Vascular endothelial growth factor receptors | Medicine | Inhibitors | Arachidonate 12-lipoxygenase | Liquid oxygen | In vivo methods and tests | Diabetes | Lipoxygenase | Protein-tyrosine-phosphatase
Journal Article
Breast Cancer Research, ISSN 1465-5411, 06/2018, Volume 20, Issue 1, pp. 55 - 17
Background: Altered lipid metabolism is an emerging hallmark of aggressive breast cancers. The N-myc downstream regulated gene (NDRG1) gene plays a critical... 
Metabolomics | Marker | Metabolism | Lipogenic | Aggressiveness | SURVIVAL | QUANTIFICATION | TRAFFICKING | QUADRUPOLE | AUTOPHAGY | METASTASIS SUPPRESSOR | ONCOLOGY | TUMOR-METASTASIS | GROWTH | GENE-EXPRESSION | DRG-1 | Care and treatment | Cancer cells | Breast cancer | Research | Lipid metabolism | Gene expression | Health aspects
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0182534
Journal Article
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology, ISSN 0363-6119, 11/2011, Volume 301, Issue 5, pp. 1307 - 1317
Studies suggest that soluble epoxide hydrolase (sEH) inhibition reduces end-organ damage in cardiovascular diseases. We hypothesize that sEH gene (Ephx2)... 
NF-κB | Afferent arteriolar relaxation | HO-1 | Albuminuria | NADPH oxidase | PHYSIOLOGY | RATS | 11,12-EPOXYEICOSATRIENOIC ACID | NEPHROPATHY | BLOOD-PRESSURE | albuminuria | GROWTH-FACTOR-BETA | NF-kappa B | SALT-SENSITIVE HYPERTENSION | IN-VIVO | HEME OXYGENASE-1 | afferent arteriolar relaxation | EPOXYEICOSATRIENOIC ACIDS | Heme Oxygenase-1 - metabolism | Kidney - blood supply | Kidney - pathology | Oxidative Stress | Diabetic Nephropathies - etiology | Kidney - enzymology | Diabetes Mellitus, Experimental - genetics | NADPH Oxidases - metabolism | Endothelium, Vascular - drug effects | Male | Nephritis - prevention & control | Membrane Proteins - urine | Time Factors | Collagen - urine | Diabetes Mellitus, Experimental - complications | Diabetic Nephropathies - prevention & control | Diabetes Mellitus, Experimental - physiopathology | Kidney - drug effects | Diabetes Mellitus, Type 1 - pathology | Nephritis - etiology | Epoxide Hydrolases - genetics | Mice, Knockout | Mice | Vasodilation - drug effects | Diabetic Nephropathies - enzymology | Phosphorylation | Diabetes Mellitus, Experimental - enzymology | Nephritis - genetics | Nephritis - pathology | Diabetes Mellitus, Type 1 - complications | Dose-Response Relationship, Drug | Diabetic Nephropathies - physiopathology | I-kappa B Kinase - metabolism | Inflammation Mediators - metabolism | Membrane Proteins - metabolism | Diabetes Mellitus, Type 1 - enzymology | Epoxide Hydrolases - deficiency | Nephritis - enzymology | Diabetic Nephropathies - pathology | Vasodilator Agents - pharmacology | Diabetes Mellitus, Type 1 - physiopathology | Mice, Inbred C57BL | Endothelium, Vascular - physiopathology | Diabetes Mellitus, Type 1 - genetics | Diabetic Nephropathies - genetics | Thiobarbituric Acid Reactive Substances - metabolism | Albuminuria - prevention & control | Albuminuria - enzymology | Animals | Transcription Factor RelA - metabolism | Chemokine CCL2 - urine | Diabetes Mellitus, Experimental - pathology | Prevention | Enzymes | Type 1 diabetes | Streptozocin | Physiological aspects | Hydrolases | Genetic aspects | Inflammation | Health aspects | Endothelium | Translational Physiology
Journal Article
Clinical Science, ISSN 0143-5221, 10/2013, Volume 125, Issue 7, pp. 349 - 359
We have shown previously that inhibition of sEH (soluble epoxide hydrolase) increased EETs (epoxyeicosatrienoic acids) levels and reduced renal injury in... 
Inflammation | Diabetic renal injury | Albuminuria | Soluble epoxide hydrolase (SEH) | Haem oxygenase | haem oxygenase | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | soluble epoxide hydrolase (sEH) | 11,12-EPOXYEICOSATRIENOIC ACID | diabetic renal injury | LOWERS BLOOD-PRESSURE | GLOMERULAR INJURY | NEPHROPATHY | albuminuria | GROWTH-FACTOR-BETA | inflammation | RENAL INFLAMMATION | GENE-EXPRESSION | EPOXYEICOSATRIENOIC ACIDS | MEDULLARY INTERSTITIAL-CELLS | Diabetes Mellitus, Experimental - drug therapy | Diabetic Nephropathies - enzymology | Heme Oxygenase-1 - metabolism | Benzoates - therapeutic use | Diabetes Mellitus, Experimental - enzymology | Epoxide Hydrolases - physiology | Kidney Cortex - metabolism | Actins - metabolism | Male | Membrane Proteins - urine | Metalloporphyrins - pharmacology | Urea - analogs & derivatives | Heme Oxygenase-1 - physiology | Blood Pressure - drug effects | Blood Pressure - physiology | Heme Oxygenase (Decyclizing) - antagonists & inhibitors | Heme Oxygenase (Decyclizing) - metabolism | Diabetic Nephropathies - prevention & control | Diabetes Mellitus, Experimental - physiopathology | Rats, Inbred SHR | Drug Evaluation, Preclinical - methods | Heme Oxygenase (Decyclizing) - physiology | Diabetic Nephropathies - metabolism | Enzyme Inhibitors - pharmacology | Rats | Albuminuria - prevention & control | Creatinine - urine | Enzyme Inhibitors - therapeutic use | Heme Oxygenase-1 - antagonists & inhibitors | Benzoates - antagonists & inhibitors | Disease Progression | Urea - antagonists & inhibitors | Urea - therapeutic use | Animals | Benzoates - pharmacology | Epoxide Hydrolases - metabolism | Epoxide Hydrolases - antagonists & inhibitors | Urea - pharmacology
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 2
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Intravenous administration | Supplementation
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 18050 - 13
Journal Article
Diabetes, ISSN 0012-1797, 02/2011, Volume 60, Issue 2, pp. 614 - 624
Journal Article
Medicine & Science in Sports & Exercise, ISSN 0195-9131, 05/2018, Volume 50, pp. 112 - 113
Journal Article