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Islets, ISSN 1938-2014, 03/2014, Volume 6, Issue 2, pp. e28686 - e28686-5
Regenerative therapy in diabetes with the capacity to reconstitute a functional β-cell mass sufficient for glycemic control holds the promise to effectively... 
betatrophin | RIFL | Lipasin | AGNPTL8 | diabetes | MOUSE | RECEPTOR | HYPERPLASIA | IDENTIFICATION | METABOLISM | GLUCOSE | ENDOCRINOLOGY & METABOLISM | INSULIN-RESISTANT STATES | GROWTH-FACTOR
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2016, Volume 126, Issue 3, pp. 1109 - 1113
It has been reported that endogenous retroviruses can contaminate human cell lines that have been passaged as xenotransplants in immunocompromised mice. We... 
Pancreatic beta cells | Usage | Xenotropic murine leukemia virus-related virus | Analysis | Xenotransplantation | Risk factors | Hostages | T cells | Leukemia | Cells | Proteins | Antigens | Propagation | Laboratories | Genes | Viruses | Genomes | Scientific imaging | Diabetes | Experiments | Mass spectrometry | Molecular weight
Journal Article
Islets, 2014, Volume 6, Issue 2, pp. e28686 - e28686
Regenerative therapy in diabetes with the capacity to reconstitute a functional β-cell mass sufficient for glycemic control holds the promise to effectively... 
Peptide Hormones - metabolism | Insulin-Secreting Cells - metabolism | Animals | Cell Proliferation | Humans | Pancreas - cytology | Female | Male | Index Medicus
Journal Article
Ugeskrift for Laeger, ISSN 0041-5782, 09/2010, Volume 172, Issue 38, pp. 2608 - 2612
Journal Article
Academie des Sciences. Comptes Rendus. Biologies, ISSN 1631-0691, 06/2007, Volume 330, Issue 6-7, pp. 534 - 537
Blood glucose regulation has likely evolved during early vertebrate evolution to allow and secure the concurrent evolution of complex brains and nervous... 
Journal Article
Diabetes, ISSN 0012-1797, 12/2015, Volume 64, Issue 12, p. 4148
  Insulin-like growth factor 2 (IGF2), produced and secreted by adult ...-cells, functions as an autocrine activator of the ...-cell insulin-like growth factor... 
Rodents | Adults | Insulin-like growth factors | Glucose | Metabolism | Cells
Journal Article
Diabetes, ISSN 0012-1797, 12/2015, Volume 64, Issue 12, pp. 4148 - 4157
Journal Article
Developmental Biology, ISSN 0012-1606, 2003, Volume 260, Issue 2, pp. 426 - 437
Mice carrying loss-of-function mutations in certain Notch pathway genes display increased and accelerated pancreatic endocrine development, leading to... 
Duct | Embryology | Notch | Gut | PDX1 | Development | Endocrine | Exocrine | Nkx6.1 | Pancreas | PDXI | exocrine | development | gut | BETA-CELLS | LOOP | MAMMALIAN NOTCH | DEVELOPMENTAL BIOLOGY | duct | PDX-1 | GENE | SIGNALING PATHWAY | pancreas | notch | embryology | NKX 6.1 | TRANSCRIPTION FACTOR | EXPRESSION | endocrine | INTRACELLULAR DOMAIN
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 01/2016, Volume 30, Issue 1, pp. 133 - 143
Diabetes is characterized by insulin insufficiency due to a relative paucity of functional [beta]-cell mass. Thus, strategies for increasing [beta]-cell mass... 
Journal Article
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 01/2016, Volume 30, Issue 1, pp. 133 - 143
Diabetes is characterized by insulin insufficiency due to a relative paucity of functional β-cell mass. Thus, strategies for increasing β-cell mass in situ are... 
CYCLOPHILIN-B | PROLACTIN RECEPTOR | PANCREATIC-ISLETS | RNA | INSULIN-SECRETION | GROWTH | MOUSE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | PROLIFERATION | PREGNANCY | Pregnancy | Insulin-Secreting Cells - metabolism | Animals | Islets of Langerhans - metabolism | Cell Proliferation - physiology | Female | Mice | Proteomics - methods | Index Medicus | Research Resource
Journal Article
Developmental Biology, ISSN 0012-1606, 2005, Volume 286, Issue 1, pp. 217 - 224
Recently, the expression of the peptide hormone ghrelin was detected in α-cells of the islets of Langerhans as well as in ε-cells, a newly discovered endocrine... 
Glucagon | Ghrelin | Arx | Neurogenin3 | Pax4 | Development | Endocrine | Pax6 | Pancreas | HOMEODOMAIN TRANSCRIPTION FACTOR | development | ALPHA-CELLS | MOUSE PANCREAS | BETA-CELLS | INSULIN-SECRETION | ISLET-CELL | DEVELOPMENTAL BIOLOGY | ghrelin | HORMONE | pancreas | glucagon | DIFFERENTIATION | neurogenin3 | endocrine | Paired Box Transcription Factors - genetics | Paired Box Transcription Factors - deficiency | Homeodomain Proteins - metabolism | Nerve Tissue Proteins - deficiency | Transcription Factors - deficiency | Green Fluorescent Proteins - genetics | Peptide Hormones - genetics | Peptide Hormones - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Islets of Langerhans - metabolism | Mice, Mutant Strains | Islets of Langerhans - cytology | Eye Proteins - genetics | Basic Helix-Loop-Helix Transcription Factors - deficiency | Repressor Proteins - metabolism | Recombinant Proteins - metabolism | Green Fluorescent Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Repressor Proteins - genetics | Mice, Transgenic | PAX6 Transcription Factor | Recombinant Proteins - genetics | Transcription Factors - genetics | Nerve Tissue Proteins - genetics | Homeodomain Proteins - genetics | Nerve Tissue Proteins - metabolism | Transcription Factors - metabolism | Animals | Eye Proteins - metabolism | Glucagon - metabolism | Islets of Langerhans - growth & development | Mice | Paired Box Transcription Factors - metabolism | Index Medicus | Green Fluorescent Proteins | Paired Box Transcription Factors | Repressor Proteins | Biochemistry, Molecular Biology | Nerve Tissue Proteins | Recombinant Proteins | Life Sciences | Peptide Hormones | Homeodomain Proteins | Transcription Factors | Islets of Langerhans | Molecular biology | Eye Proteins | Basic Helix-Loop-Helix Transcription Factors
Journal Article
Development, ISSN 0950-1991, 01/2012, Volume 139, Issue 1, pp. 33 - 45
Neurog3-induced Dll1 expression in pancreatic endocrine progenitors ostensibly activates Hes1 expression via Notch and thereby represses Neurog3 and endocrine... 
Neurog3 | Mouse | Notch | Hes1 | Pancreas | Dll1 | Ptf1a | TRANSCRIPTION FACTORS | DELTA | DEVELOPMENTAL BIOLOGY | ENDOCRINE DEVELOPMENT | GENE-EXPRESSION | PANCREATIC PROGENITORS | CELL-DIFFERENTIATION | MONOCLONAL-ANTIBODIES