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by Kim, Min-Sik and Pinto, Sneha M and Getnet, Derese and Nirujogi, Raja Sekhar and Manda, Srikanth S and Chaerkady, Raghothama and Madugundu, Anil K and Kelkar, Dhanashree S and Isserlin, Ruth and Jain, Shobhit and Thomas, Joji K and Muthusamy, Babylakshmi and Leal-Rojas, Pamela and Kumar, Praveen and Sahasrabuddhe, Nandini A and Balakrishnan, Lavanya and Advani, Jayshree and George, Bijesh and Renuse, Santosh and Selvan, Lakshmi Dhevi N and Patil, Arun H and Nanjappa, Vishalakshi and Radhakrishnan, Aneesha and Prasad, Samarjeet and Subbannayya, Tejaswini and Raju, Rajesh and Kumar, Manish and Sreenivasamurthy, Sreelakshmi K and Marimuthu, Arivusudar and Sathe, Gajanan J and Chavan, Sandip and Datta, Keshava K and Subbannayya, Yashwanth and Sahu, Apeksha and Yelamanchi, Soujanya D and Jayaram, Savita and Rajagopalan, Pavithra and Sharma, Jyoti and Murthy, Krishna R and Syed, Nazia and Goel, Renu and Khan, Aafaque A and Ahmad, Sartaj and Dey, Gourav and Mudgal, Keshav and Chatterjee, Aditi and Huang, Tai-Chung and Zhong, Jun and Wu, Xinyan and Shaw, Patrick G and Freed, Donald and Zahari, Muhammad S and Mukherjee, Kanchan K and Shankar, Subramanian and Mahadevan, Anita and Lam, Henry and Mitchell, Christopher J and Shankar, Susarla Krishna and Satishchandra, Parthasarathy and Schroeder, John T and Sirdeshmukh, Ravi and Maitra, Anirban and Leach, Steven D and Drake, Charles G and Halushka, Marc K and Prasad, T. S. Keshava and Hruban, Ralph H and Kerr, Candace L and Bader, Gary D and Iacobuzio-Donahue, Christine A and Gowda, Harsha and Pandey, Akhilesh
Nature, ISSN 0028-0836, 2014, Volume 509, Issue 7502, pp. 575 - 581
Journal Article
Molecular Systems Biology, ISSN 1744-4292, 2011, Volume 7, Issue 1, pp. 500 - n/a
The simultaneous utilization of efficient respiration and inefficient fermentation even in the presence of abundant oxygen is a puzzling phenomenon commonly... 
membrane occupancy | respiro‐fermentation | flux balance analysis | overflow metabolism | constraint‐based modeling | constraint-based modeling | overflowmetabolism | respiro-fermentation | YIELD | RECONSTRUCTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | SACCHAROMYCES-CEREVISIAE | EVOLUTION | OXIDASE | EXPRESSION | MICROBIAL-POPULATIONS | GROWTH-CONDITIONS | Anaerobiosis | Glucose Transport Proteins, Facilitative - metabolism | Genes, Bacterial | Electron Transport | Phosphorylation | Aerobiosis | Models, Molecular | Electron Transport Complex IV - genetics | Fermentation | Gene Knockout Techniques | Oxygen - metabolism | Electron Transport Complex IV - metabolism | Adenosine Triphosphate - metabolism | Glucose - metabolism | Cell Membrane - metabolism | Membrane Proteins - metabolism | Glucose Transport Proteins, Facilitative - genetics | Gene Expression Regulation, Bacterial | Escherichia coli - physiology | Cytochrome | Tricarboxylic acid cycle | Aerobic conditions | Escherichia coli | Glucose | Heterotrophs | Cell morphology | Proteins | Eukaryotes | Mitochondria | Microorganisms | Constraint modelling | Physiology | Economics | Enzymes | Computer simulation | Anaerobic conditions | Metabolism | Gene expression | Substrates | Membrane proteins | Physical fitness | Numerical analysis | Morphology | Predictions | Cytochromes | Acetic acid | Stoichiometry | Growth rate | Theory | Cytology | Genomes | Optimization | Overflow | Reduction | E coli | Evolution | Bacteria | Oxygen | Prokaryotes | Oxygen consumption | Oxygen uptake | Hypotheses | Protein expression | Surface area | Electron transport | Respiration | ATP | Cancer | Fitness | Index Medicus | oxidase | expression | saccharomyces-cerevisiae | escherichia-coli | evolution | microbial-populations | growth-conditions | Biokemi och molekylärbiologi | yield | Biochemistry and Molecular Biology | reconstruction
Journal Article
Journal Article
Bioinformatics (Oxford, England), ISSN 1367-4803, 06/2019
In kinetic models of metabolism, the parameter values determine the dynamic behaviour predicted by these models. Estimating parameters from in vivo... 
Journal Article
Nature Communications, ISSN 2041-1723, 05/2017, Volume 8, Issue 1, pp. 1 - 11
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2007, Volume 282, Issue 39, pp. 28791 - 28799
In this report, a genome-scale reconstruction of Bacillus subtilis metabolism and its iterative development based on the combination of genomic, biochemical,... 
RIBOFLAVIN | CARBON | ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | GROWTH | GLYCINE OXIDASE | OPERON | MODEL | IDENTIFICATION | D-ALANINE | Phenotype | Models, Biological | Computer Simulation | Bacterial Proteins - genetics | Bacterial Proteins - metabolism | Genome, Bacterial - physiology | Bacillus subtilis - metabolism | Bacillus subtilis - genetics | Index Medicus
Journal Article
Computers and Chemical Engineering, ISSN 0098-1354, 11/2019, Volume 130
Cardiovascular disease (CVD) is the leading cause of death worldwide. Studies have found that abnormally high low-density lipoprotein cholesterol (LDL-C)... 
Journal Article