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Molecular Therapy, ISSN 1525-0016, 09/2017, Volume 25, Issue 9, pp. 2176 - 2188
Anti-tumor efficacy of T cells engineered to express chimeric antigen receptors (CARs) is dependent on their specificity, survival, and in vivo expansion... 
CD40 | inducible | costimulation | T cell | chimeric antigen receptor | dimerizer | MyD88 | MEDICINE, RESEARCH & EXPERIMENTAL | EFFECTOR FUNCTIONS | TOLL-LIKE RECEPTOR | ANTITUMOR-ACTIVITY | CUTTING EDGE | THERAPY | MEMORY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | CPG-OLIGODEOXYNUCLEOTIDES | LYMPHODEPLETION | COSTIMULATION | EXPRESSION | Cell Proliferation | Humans | Gene Expression Profiling | Leukemia - metabolism | Recombinant Fusion Proteins | CD28 Antigens - metabolism | Lymphocyte Activation - immunology | CD40 Antigens - metabolism | CD28 Antigens - genetics | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | CD40 Antigens - genetics | Toll-Like Receptors - metabolism | Leukemia - genetics | Disease Models, Animal | Immunotherapy, Adoptive - methods | Receptors, Antigen, T-Cell - metabolism | Signal Transduction | Cell Survival | Leukemia - therapy | Xenograft Model Antitumor Assays | Animals | Leukemia - immunology | Lymphocyte Activation - drug effects | T-Lymphocytes - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Cluster Analysis | Cell proliferation | Antigens | Graft-versus-host reaction | CD40 antigen | Cell survival | Cytokines | CD8 antigen | Cytotoxicity | T cell receptors | Lymphocytes T | Gene expression | Kinases | Adoptive transfer | CD4 antigen | Cell growth | Cell activation | Lymphocytes | Toll-like receptors | MyD88 protein | Tumor necrosis factor-TNF | Ligands | Software | Tumors | Original
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. LB-141 - LB-141
Journal Article
Journal Article
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 1121 - 1121
Abstract Introduction: Adoptive transfer of T cells genetically engineered to express chimeric antigen receptors (CARs) has begun to show impressive clinical... 
Journal Article
Oncotarget, ISSN 1949-2553, 03/2019, Volume 10, Issue 24, p. 2369
After unprecedented successes in B-cell malignancies, chimeric antigen receptor T cells have recently been investigated for the treatment of multiple myeloma.... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 4551 - 4551
Abstract Introduction: Promising clinical results with CD19-specific chimeric antigen receptor (CAR)-directed T cells for the treatment of B cell leukemia and... 
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2016, Volume 34, Issue 15_suppl, pp. 3050 - 3050
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2015, Volume 33, Issue 15_suppl, pp. 3064 - 3064
Journal Article
by Lundqvist, Andreas and van Hoef, Vincent and Zhang, Xiaonan and Wennerberg, Erik and Lorent, Julie and Witt, Kristina and Sanz, Laia Masvidal and Liang, Shuo and Murray, Shannon and Larsson, Ola and Kiessling, Rolf and Mao, Yumeng and Sidhom, John-William and Bessell, Catherine A and Havel, Jonathan and Schneck, Jonathan and Chan, Timothy A and Sachsenmeier, Eliot and Woods, David and Berglund, Anders and Ramakrishnan, Rupal and Sodre, Andressa and Weber, Jeffrey and Zappasodi, Roberta and Li, Yanyun and Qi, Jingjing and Wong, Philip and Sirard, Cynthia and Postow, Michael and Newman, Walter and Koon, Henry and Velcheti, Vamsidhar and Callahan, Margaret K and Wolchok, Jedd D and Merghoub, Taha and Lum, Lawrence G and Choi, Minsig and Thakur, Archana and Deol, Abhinav and Dyson, Gregory and Shields, Anthony and Haymaker, Cara and Uemura, Marc and Murthy, Ravi and James, Marihella and Wang, Daqing and Brevard, Julie and Monaghan, Catherine and Swann, Suzanne and Geib, James and Cornfeld, Mark and Chunduru, Srinivas and Agrawal, Sudhir and Yee, Cassian and Wargo, Jennifer and Patel, Sapna P and Amaria, Rodabe and Tawbi, Hussein and Glitza, Isabella and Woodman, Scott and Hwu, Wen-Jen and Davies, Michael A and Hwu, Patrick and Overwijk, Willem W and Bernatchez, Chantale and Diab, Adi and Massarelli, Erminia and Segal, Neil H and Ribrag, Vincent and Melero, Ignacio and Gangadhar, Tara C and Urba, Walter and Schadendorf, Dirk and Ferris, Robert L and Houot, Roch and Morschhauser, Franck and Logan, Theodore and Luke, Jason J and Sharfman, William and Barlesi, Fabrice and Ott, Patrick A and Mansi, Laura and Kummar, Shivaani and Salles, Gilles and Carpio, Cecilia and Meier, Roland and Krishnan, Suba and McDonald, Dan and Maurer, Matthew and Gu, Xuemin and Neely, Jaclyn and Suryawanshi, Satyendra and Levy, Ronald and Khushalani, Nikhil and Wu, Jennifer and Zhang, Jinyu and Basher, Fahmin and Rubinstein, Mark and Bucsek, Mark and Qiao, Guanxi and ...
Journal for ImmunoTherapy of Cancer, ISSN 2051-1426, 11/2016, Volume 4, Issue S1
Journal Article
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