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1. Full Text eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies
by Boussemart, Lise and Malka-Mahieu, Hélène and Girault, Isabelle and Allard, Delphine and Hemmingsson, Oskar and Tomasic, Gorana and Thomas, Marina and Basmadjian, Christine and Ribeiro, Nigel and Thuaud, Frédéric and Mateus, Christina and Routier, Emilie and Kamsu-Kom, Nyam and Agoussi, Sandrine and Eggermont, Alexander M and Désaubry, Laurent and Robert, Caroline and Vagner, Stéphan
Nature (London), ISSN 0028-0836, 2014, Volume 513, Issue 7516, pp. 105 - 109
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Triterpenes - pharmacology | Humans | Eukaryotic Initiation Factor-4E - metabolism | Eukaryotic Initiation Factor-4G - metabolism | Eukaryotic Initiation Factor-4F - metabolism | Melanoma - genetics | Protein Binding - drug effects | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Phosphorylation - drug effects | Eukaryotic Initiation Factor-4F - antagonists & inhibitors | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Melanoma - pathology | Sulfonamides - pharmacology | Eukaryotic Initiation Factor-4A - antagonists & inhibitors | Drug Synergism | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | MAP Kinase Signaling System - drug effects | Eukaryotic Initiation Factor-4F - chemistry | Signal Transduction - drug effects | Proto-Oncogene Proteins B-raf - genetics | Colonic Neoplasms - pathology | Melanoma - drug therapy | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Eukaryotic Initiation Factor-4A - metabolism | Drug Resistance, Neoplasm - drug effects | Thyroid Neoplasms - pathology | Antimitotic agents | Pharmaceutical research | Vemurafenib | Protein research | Research | Antineoplastic agents | Drug resistance | Phosphorylation | Biopsy | Melanoma | Mutation | Metastasis | Cancer therapies | Tumors | Cancer | Index Medicus
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2. Full Text Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma
by Cerezo, Michaël and Guemiri, Ramdane and Druillennec, Sabine and Girault, Isabelle and Malka-Mahieu, Hélène and Shen, Shensi and Allard, Delphine and Martineau, Sylvain and Welsch, Caroline and Agoussi, Sandrine and Estrada, Charlène and Adam, Julien and Libenciuc, Cristina and Routier, Emilie and Roy, Séverine and Désaubry, Laurent and Eggermont, Alexander M and Sonenberg, Nahum and Scoazec, Jean Yves and Eychène, Alain and Vagner, Stéphan and Robert, Caroline
Nature medicine, ISSN 1078-8956, 12/2018, Volume 24, Issue 12, pp. 1877 - 1886
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Tumor Escape - drug effects | Protein Biosynthesis | Humans | B7-H1 Antigen - therapeutic use | Eukaryotic Initiation Factor-4F - genetics | Gene Expression Regulation, Neoplastic - immunology | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Melanoma - pathology | STAT1 Transcription Factor - genetics | B7-H1 Antigen - genetics | B7-H1 Antigen - immunology | Animals | B7-H1 Antigen - antagonists & inhibitors | Signal Transduction - drug effects | Melanoma - genetics | Melanoma - immunology | Immunotherapy | Interferon-gamma - immunology | Cell Line, Tumor | Mice | Programmed Cell Death 1 Receptor - therapeutic use | Interferon-gamma - genetics | Melanoma - therapy | Tumor Escape - immunology | Prevention | Usage | Care and treatment | Analysis | Oncology, Experimental | Melanoma | Research | Biological response modifiers | Apoptosis | Cancer | Complex formation | PD-1 protein | Drug development | Immunosuppressive agents | Anticancer properties | DNA helicase | Antitumor agents | Stat1 protein | Initiation complex | Translation | Tumor cells | Translation initiation | Pharmacology | Ribonucleic acid--RNA | Immune checkpoint | PD-L1 protein | Biomarkers | Antitumor activity | Interferon | RNA helicase | Tumors | Index Medicus | Life Sciences
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3. Full Text Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study
by Howard, James F and Utsugisawa, Kimiaki and Benatar, Michael and Murai, Hiroyuki and Barohn, Richard J and Illa, Isabel and Jacob, Saiju and Vissing, John and Burns, Ted M and Kissel, John T and Muppidi, Srikanth and Nowak, Richard J and O'Brien, Fanny and Wang, Jing-Jing and Mantegazza, Renato and Mazia, Claudio Gabriel and Wilken, Miguel and Ortea, Carolina and Saba, Juliet and Rugiero, Marcelo and Bettini, Mariela and Vidal, Gonzalo and Garcia, Alejandra Dalila and Lamont, Phillipa and Leong, Wai-Kuen and Fyfe, Beverly and Roberts, Leslie and Jasinarachchi, Mahi and Wanschitz, Julia and Löscher, Wolfgang and De Bleecker, Jan and de Koning, Kathy and De Mey, Katrien and Mercelis, Rudy and Van Damme, Philip and Smetcoren, Charlotte and Stevens, Olivier and D'Hondt, Ann and Tilkin, Petra and Alves de Siqueira Carvalho, Alzira and Feder, David and Ambrosio, Daniel and Melo, Ana Paula and Rocha, Rosana and Rosa, Bruno and Augusto da Silva, Luiz and Gonçalves Geraldo, Jordana and da Penha Morita Ananias, Maria and Paiva, Gabriel and Pozo, Marina and Prando, Natalia and Dada Martineli Torres, Debora and Fernanda Butinhao, Cristiani and Coelho, Erica and Renata Cubas Volpe, Luciana and Duran, Gustavo and Gomes da Silva, Tamires Cristina and Otavio Maia Gonçalves, Luiz and Souza Duca, Luciana and Suriane Fialho, Tomás Augusto and Guerreiro, Alexandre and Mohr, Henrique and Pereira Martins, Maurer and da Cruz Pacheco, Daiane and de Cassia Santos, Aline and Bulle Oliveira, Acary Souza and Annes, Marcelo and Cavalcante Lino, Valeria and Miranda, Carolina and Souza, Iandra and Genge, Angela and Massie, Rami and Campbell, Natasha and Katzberg, Hans and Soltani, Mehran and Siddiqi, Zaeem and Phan, Celile and Blackmore, Derrick and Vohanka, Stanislav and Chmelikova, Magda and Cierny, Marek and Kurkova, Barbora and Zapletalova, Olga and Pitha, Jiri and Tyblova, Michaela and Wolfova, Marcela and Jurajdova, Ivana and Andersen, Henning and Harbo, Thomas and Vinge, Lotte and Mogensen, Anita and Højgaard, Joan and Witting, Nanna and Autzen, Anne Mette and Pedersen, Jane and Färkkilä, Markus and Atula, Sari and Erälinna, Juha-Pekka and Laaksonen, Mikko and Harrison, Tuula and ... and REGAIN Study Group and REGAIN Study Grp
Lancet neurology, ISSN 1474-4422, 12/2017, Volume 16, Issue 12, pp. 976 - 986
no | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Severity of Illness Index | Antibodies, Monoclonal, Humanized - adverse effects | Double-Blind Method | Myasthenia Gravis - blood | Outcome Assessment (Health Care) | Autoantibodies - blood | Humans | Middle Aged | Male | Antibodies, Monoclonal, Humanized - administration & dosage | Myasthenia Gravis - physiopathology | Antibodies, Monoclonal, Humanized - pharmacology | Adult | Female | Receptors, Cholinergic - immunology | Aged | Myasthenia Gravis - drug therapy | Drug Resistance | Studies | Neurology | Immunoglobulins | Activities of daily living | Myasthenia gravis | Transplants & implants | Neuromuscular junctions | Myasthenia | Patients | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Clinical Management of Argentine Hemorrhagic Fever using Ribavirin and Favipiravir, Belgium, 2020
by Veliziotis, Ioannis and Roman, Alain and Martiny, Delphine and Schuldt, Gerlind and Claus, Marc and Dauby, Nicolas and Van den Wijngaert, Sigi and Martin, Charlotte and Nasreddine, Rakan and Perandones, Claudia and Mahieu, Romain and Swaan, Corien and Van Praet, Serge and Konopnicki, Deborah and Morales, Maria A and Malvy, Denis and Stevens, Etienne and Dechamps, Philippe and Vlieghe, Erika and Vandenberg, Olivier and Guenther, Stephan and Gerard, Michele
Emerging infectious diseases, ISSN 1080-6040, 07/2020, Volume 26, Issue 7, pp. 1562 - 1566
Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | Hemorrhagic fever | Lassa fever | Vaccines | Tazobactam | Ribavirin | Levetiracetam | Personal protective equipment | Medical personnel | Plasma | Intensive care | Laboratories | Infections | Hospitalization | Fever | Airway management | Infectious diseases | Hospitals | Illnesses | Influenza | Drug dosages | Public health | Index Medicus | Argentine hemorrhagic fever | clinical management | viruses | ribavirin | Clinical Management of Argentine Hemorrhagic Fever using Ribavirin and Favipiravir, Belgium, 2020 | antiviral drugs | Dispatch | Junin virus | JUNV | containment | Belgium | New World arenaviruses | travel | favipiravir | public health
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5. Full Text Paediatric optic neuritis: factors leading to unfavourable outcome and relapses
by Averseng-Peaureaux, Delphine and Mizzi, Marie and Colineaux, Helene and Mahieu, Laurence and Pera, Maria Carmela and Brassat, David and Chaix, Yves and Berard, Emilie and Deiva, Kumaran and Cheuret, Emmanuel and Kidbiosep Study Grp and Kidbiosep study group
British journal of ophthalmology, ISSN 0007-1161, 06/2018, Volume 102, Issue 6, pp. 808 - 813
Life Sciences & Biomedicine | Ophthalmology | Science & Technology | Multivariate Analysis | Optic Nerve - pathology | Recurrence | Humans | Risk Factors | Kaplan-Meier Estimate | Male | Multiple Sclerosis - complications | Magnetic Resonance Imaging | Optic Neuritis - physiopathology | Adolescent | Adult | Female | Retrospective Studies | Child | Visual Acuity - physiology | Studies | Neurology | Pediatrics | Multiple sclerosis | Optic nerve | Pain | Glycoproteins | Patients | Index Medicus
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6. Full Text Streptococcus pyogenes infections with limited emm-type diversity in the homeless population of Brussels, 2016–2018
by Dauby, Nicolas and Miendje Deyi, Véronique Yvette and Delforge, Valérie and Martiny, Delphine and Mekkaoui, Leila and Hallin, Marie and Mahieu, Romain and Bossuyt, Nathalie and Botteaux, Anne and Smeesters, Pierre R
International journal of infectious diseases, ISSN 1201-9712, 04/2019, Volume 81, pp. 52 - 56
Homeless persons | Streptococcus pyogenes | Skin infections | Epidemiology | Streptococcal m protein | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Homelessness | Medical research | Analysis | Abscess | Medicine, Experimental | Skin | Health aspects | Index Medicus
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7. Full Text Screening and infectious diseases of new migrants in France: A retrospective cross-sectional study
by Douillet, Delphine and Mahieu, Rafaël and Delori, Maud and Baudry, Emmanuel and Griffiths, Karolina and Roy, Pierre-Marie and Vandamme, Yves-Marie
Travel medicine and infectious disease, ISSN 1477-8939, 2017, Volume 17, pp. 64 - 65
Infectious Disease | New migrants | Screening | Infectious diseases | Public, Environmental & Occupational Health | Infectious Diseases | Life Sciences & Biomedicine | Science & Technology | Public Health | Mass Screening | Cross-Sectional Studies | Humans | Adult | Communicable Diseases - diagnosis | Female | Male | Retrospective Studies | France | Emigrants and Immigrants | Medical screening | Emergency medicine | Communicable diseases | Aliens | Migrants | Tuberculosis | Migrant workers | Human immunodeficiency virus--HIV | Public health | Index Medicus
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8. Full Text Validity of the French version of the Core Outcome Measures Index for low back pain patients: a prospective cohort study
by Genevay, Stéphane and Marty, Marc and Courvoisier, Delphine S and Foltz, Violaine and Mahieu, Geneviève and Demoulin, Christophe and Fontana, Agnieszka Gierasimowicz and Norberg, Michael and de Goumoëns, Pierre and Cedraschi, Christine and Rozenberg, Sylvie and Sect Rachisde Soc Francaise and Section Rachisde la Société Française de Rhumatologie
European spine journal, ISSN 0940-6719, 10/2014, Volume 23, Issue 10, pp. 2097 - 2104
Surgical Orthopedics | Medicine & Public Health | Multidimensional assessment | Self-report questionnaire | Low back pain | Psychometrics | Neurosurgery | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Orthopedics | Science & Technology | Disability Evaluation | Reproducibility of Results | Prospective Studies | Humans | Middle Aged | Self Report | Male | Low Back Pain - diagnosis | Outcome Assessment (Health Care) - standards | Language | Employment | Psychometrics - standards | Psychometrics - methods | Adult | Female | ROC Curve | Sick Leave | Surveys and Questionnaires - standards | Medicine, Experimental | Medical research | Backache | Analysis | Patient outcomes | Index Medicus
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9. Full Text Impact of faecal microbiota transplantation on mouse digestive colonization with two extensively resistant bacteria
by Mahieu, Rafael and Cassisa, Viviane and Hilliquin, Delphine and Coron, Noémie and Pailhoriès, Hélène and Kempf, Marie and Joly-Guillou, Marie-Laure and Eveillard, Matthieu
The Journal of infection, ISSN 0163-4453, 2017, Volume 75, Issue 1, pp. 75 - 77
Infectious Disease | Digestive colonization | Faecal microbiota transplantation | Mouse model | Carbapenem-producing Enterobacteriaceae | Vancomycin-resistant Enterococcus faecium | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Enterococcus faecium | Anti-Bacterial Agents | Gram-Positive Bacterial Infections | Animals | Mice | Feces | Fecal Microbiota Transplantation | Microbiota (Symbiotic organisms) | Bacteria | Index Medicus | Life Sciences | Cancer
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10. Full Text Outpatient management or hospitalization of patients with proven or suspected SARS-CoV-2 infection: the HOME-CoV rule
by Douillet, Delphine and Mahieu, Rafaël and Boiveau, Violette and Vandamme, Yves-Marie and Armand, Aurore and Morin, Francois and Savary, Dominique and Dubée, Vincent and Annweiler, Cédric and Roy, Pierre-Marie and Andrianjafy, H and Annweiler, C and Armand, A and Baudin, L and Bekhir, L and Benezit, F and Benhammouda, K and Bissolokele, P and Blanchi, S and Boiveau, Violette and Bouiller, K and Bouillon, J.-B and Brice, C and Brunel, A.-S and Cayeux, C and Cazenave, B and Chauvin, A and Claessens, Y.-E and Cormier, H and Coustilleres, F and Crochette, N and Acqua, D. Dall and Douillet, Delphine and Dupriez, F and Friou, E and Gangloff, C and Gennai, S and Joly, L.-M and Karam, H.-H and Le Bot, A and Lemaignen, A and Leroy, A and Mahieu, Rafaël and Marchant, N and Marjanovic, N and Montassier, E and Morin, F and Pasquier, J and Patrat-Delon, S and Penaloza, A and Plantefeve, G and Roy, P.-M and Sanderink, D and Savary, D and Schmidt, J and Schotte, T and Soulie, C and Tchangai-Kao, S and Thiebaud, P.-C and Timsit, E and Trabattoni, E and Turmel, J.-M and Vandamme, Yves-Marie and Violeau, M and Yombi, J.-C and HOME-CoV Expert Grp and HOME-CoV expert group
Internal and emergency medicine, ISSN 1828-0447, 11/2020, Volume 15, Issue 8, pp. 1525 - 1531
COVID-19 | Hospitalization | Outpatient | Delphi method | Rule-based decision-making | Expert consensus | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Pneumonia, Viral - therapy | Humans | Middle Aged | Risk Factors | Ambulatory Care - methods | Hospitalization - statistics & numerical data | Male | Pandemics - statistics & numerical data | Outpatients - statistics & numerical data | Delphi Technique | Coronavirus Infections - epidemiology | Pneumonia, Viral - epidemiology | Coronavirus Infections - therapy | Surveys and Questionnaires | Aged | Ambulatory Care - trends | Literature reviews | Severe acute respiratory syndrome coronavirus 2 | Infectious diseases | Pandemics | Decision making | Management decisions | Coronaviruses | Patients | Index Medicus | Life Sciences | Human health and pathology
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11. Full Text FDXR Mutations Cause Sensorial Neuropathies and Expand the Spectrum of Mitochondrial Fe-S-Synthesis Diseases
by Paul, Antoine and Drecourt, Anthony and Petit, Floriane and Deguine, Delphine Dupin and Vasnier, Christelle and Oufadem, Myriam and Masson, Cécile and Bonnet, Crystel and Masmoudi, Saber and Mosnier, Isabelle and Mahieu, Laurence and Bouccara, Didier and Kaplan, Josseline and Challe, Georges and Domange, Christelle and Mochel, Fanny and Sterkers, Olivier and Gerber, Sylvie and Nitschke, Patrick and Bole-Feysot, Christine and Jonard, Laurence and Gherbi, Souad and Mercati, Oriane and Ben Aissa, Ines and Lyonnet, Stanislas and Rötig, Agnès and Delahodde, Agnès and Marlin, Sandrine
American journal of human genetics, ISSN 0002-9297, 10/2017, Volume 101, Issue 4, pp. 630 - 637
optic atrophy | iron overload | ARH1 | Auditory neuropathy | iron-sulfur cluster | mitochondria | FDXR | Fe-S cluster synthesis | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Ferredoxin-NADP Reductase - metabolism | Mitochondrial Diseases - pathology | Mitochondria - enzymology | Saccharomyces cerevisiae - genetics | Humans | Child, Preschool | Iron-Sulfur Proteins - genetics | Male | Hearing Loss, Central - genetics | Genetic Complementation Test | Optic Atrophy - pathology | Saccharomyces cerevisiae - metabolism | Young Adult | Hearing Loss, Central - enzymology | Mitochondria - genetics | Ferredoxin-NADP Reductase - genetics | Adult | Female | Optic Atrophy - genetics | Mitochondrial Diseases - genetics | Amino Acid Sequence | Mitochondria - pathology | Saccharomyces cerevisiae Proteins - genetics | Iron - metabolism | Mitochondrial Diseases - enzymology | Sequence Alignment | Pedigree | Adolescent | Saccharomyces cerevisiae Proteins - metabolism | Iron-Sulfur Proteins - metabolism | Ferredoxin-NADP Reductase - chemistry | Mutation | Hearing Loss, Central - pathology | Optic Atrophy - enzymology | Saccharomyces cerevisiae - growth & development | Usage | Gene mutations | Analysis | Genetic aspects | Nucleotide sequencing | Research | Children | Gene expression | Health aspects | DNA sequencing | Hearing loss | Index Medicus | Life Sciences | Report
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