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1. Full Text Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders
by Mahley, Robert W
Journal of molecular medicine (Berlin, Germany), ISSN 0946-2716, 7/2016, Volume 94, Issue 7, pp. 739 - 746
Human Genetics | Biomedicine | Alzheimer’s disease | Atherosclerosis | Internal Medicine | Molecular Medicine | ApoE | Cholesterol | Small-molecule structure correctors | Genetics & Heredity | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Phosphorylation | Apolipoprotein E4 - genetics | Lipoproteins, HDL - genetics | Humans | Lipoproteins, HDL - metabolism | tau Proteins - metabolism | Cardiovascular Diseases - pathology | Lipoproteins, LDL - genetics | Cardiovascular Diseases - genetics | tau Proteins - genetics | Lipoproteins, LDL - metabolism | Protein Interaction Domains and Motifs | Receptors, LDL - genetics | Apolipoprotein E4 - metabolism | Neurodegenerative Diseases - pathology | Cardiovascular Diseases - metabolism | Signal Transduction | Apolipoprotein E2 - genetics | Gene Expression Regulation | Models, Molecular | Receptors, LDL - metabolism | Neurodegenerative Diseases - genetics | Neurodegenerative Diseases - metabolism | Apolipoprotein E3 - metabolism | Cholesterol - metabolism | Apolipoprotein E2 - metabolism | Apolipoprotein E3 - genetics | Apolipoprotein E3 - chemistry | Apolipoprotein E4 - chemistry | Physiological aspects | Development and progression | Nervous system | Genetic aspects | Degeneration | Research | Cardiovascular diseases | Apolipoproteins | Index Medicus | Molecules in Medicine
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2. Full Text Apolipoprotein E Sets the Stage: Response to Injury Triggers Neuropathology
by Mahley, Robert W and Huang, Yadong
Neuron (Cambridge, Mass.), ISSN 0896-6273, 12/2012, Volume 76, Issue 5, pp. 871 - 885
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Humans | Gene Expression Regulation - physiology | Models, Molecular | Brain Injuries - genetics | Brain Injuries - metabolism | Nervous System Diseases - genetics | Apolipoproteins E - metabolism | Apolipoproteins E - chemistry | Protein Transport | Gene Expression Regulation - drug effects | Animals | Apolipoproteins E - genetics | Nervous System Diseases - etiology | Nervous System Diseases - metabolism | Brain Injuries - etiology | Proteins | Enzymes | Lipoproteins | Hypotheses | Neurotoxicity | Disease | Pathogenesis | Neuropathology | Lipids | Apolipoproteins | Cholesterol | Index Medicus | Apolipoprotein E4 | Traumatic brain injury | Neurons | Data processing | Risk factors | Stress | Mitochondria | Reviews | Apolipoprotein E | Proteolysis | Cytoskeleton
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3. Full Text Central nervous system lipoproteins: ApoE and regulation of cholesterol metabolism
by Mahley, Robert W
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 07/2016, Volume 36, Issue 7, pp. 1305 - 1315
HDL | Lipoproteins | Receptors | Neurodegenerative diseases | Alzheimer disease | Astrocytes | LDL | Apolipoproteins E | Cholesterol | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Neurons - pathology | Central Nervous System - metabolism | Neurodegenerative Diseases - pathology | Humans | Astrocytes - pathology | Central Nervous System - pathology | Neurodegenerative Diseases - metabolism | Cholesterol - metabolism | Apolipoproteins E - metabolism | Apolipoproteins E - chemistry | Animals | Neurodegenerative Diseases - physiopathology | Biological Transport | Apolipoproteins E - cerebrospinal fluid | Alzheimer Disease - metabolism | Protein Binding | Models, Animal | Neurons - metabolism | Protein Interaction Domains and Motifs | Central Nervous System - physiopathology | Nerve Degeneration | Astrocytes - metabolism | Cholesterol - cerebrospinal fluid | Index Medicus | neurodegenerative diseases | receptors, LDL | apolipoproteins E | lipoproteins, HDL | cholesterol | astrocytes
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4. Full Text Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases
by Huang, Yadong and Mahley, Robert W
Neurobiology of disease, ISSN 0969-9961, 2014, Volume 72, pp. 3 - 12
Neurology | ApoE | Mouse model | Lipid metabolism | Alzheimer's disease | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Brain - metabolism | Animals | Humans | Alzheimer Disease - metabolism | Protein Binding | Lipid Metabolism | Mice | Apolipoproteins E - metabolism | Apolipoproteins E - chemistry | Disease Models, Animal | Physiological aspects | Blood lipids | Apolipoproteins | Neurophysiology | Index Medicus
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5. Full Text Small-Molecule structure correctors target abnormal protein structure and function: Structure corrector rescue of apolipoprotein E4-associated neuropathology
by Mahley, Robert W and Huang, Yadong
Journal of medicinal chemistry, ISSN 0022-2623, 11/2012, Volume 55, Issue 21, pp. 8997 - 9008
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Proteostasis Deficiencies - metabolism | Apolipoprotein E4 - genetics | Apolipoprotein E4 - metabolism | Humans | Alzheimer Disease - drug therapy | Endoplasmic Reticulum - metabolism | Models, Molecular | Lipid Metabolism | Structure-Activity Relationship | Brain Injuries - metabolism | Molecular Targeted Therapy | Protein Transport | Animals | Protein Folding - drug effects | Alzheimer Disease - metabolism | Golgi Apparatus - metabolism | Protein Conformation | Neurons - metabolism | Proteostasis Deficiencies - drug therapy | Apolipoprotein E4 - chemistry | Index Medicus | cholesterol transport | lysosomal storage diseases | neurotoxicity | Alzheimer’s disease | neurotoxic fragments | cystic fibrosis | apoE | ER stress | mitochondrial dysfunction | proteinopathies | p53
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6. Full Text Atherogenic remnant lipoproteins: Role for proteoglycans in trapping, transferring, and internalizing
by Mahley, Robert W and Huang, Yadong
The Journal of clinical investigation, ISSN 0021-9738, 01/2007, Volume 117, Issue 1, pp. 94 - 98
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Atherosclerosis - physiopathology | Humans | Proteoglycans - metabolism | Lipoproteins - physiology | Triglycerides - metabolism | Biological Transport | Heparan Sulfate Proteoglycans - metabolism | Models, Biological | Proteoglycans - physiology | Lipoproteins - metabolism | Liver - physiology | Proteoglycans - pharmacokinetics | Receptors, LDL - physiology | Atherosclerosis - prevention & control | Heparan Sulfate Proteoglycans - physiology | Low density lipoproteins | Proteoglycans | Research | Index Medicus | Abridged Index Medicus
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7. Full Text Apolipoprotein E: Structure determines function, from atherosclerosis to Alzheimer's disease to AIDS
by Mahley, Robert W and Weisgraber, Karl H and Huang, Yadong
Journal of lipid research, ISSN 0022-2275, 04/2009, Volume 50, Issue Suppl, pp. S183 - S188
Infectious diseases | HIV | Neurodegeneration | Heparan sulfate proteoglycans | Evolution | Dysbetalipoproteinemia | Coronary heart disease | Cholesterol | LDL receptor | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Acquired Immunodeficiency Syndrome - metabolism | Atherosclerosis - genetics | Humans | Apolipoproteins E - metabolism | Acquired Immunodeficiency Syndrome - genetics | Atherosclerosis - metabolism | Apolipoproteins E - chemistry | Animals | Apolipoproteins E - genetics | Apolipoproteins E - immunology | Alzheimer Disease - metabolism | Protein Binding | Alzheimer Disease - genetics | Index Medicus | Lipoprotein Metabolism | dysbetalipoproteinemia | infectious diseases | neurodegeneration | cholesterol | coronary heart disease | evolution | heparan sulfate proteoglycans
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