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JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 10/2019, Volume 62, Issue 19, pp. 8784 - 8795
Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the rate-limiting step in the kynurenine pathway of tryptophan metabolism, which is involved in immunity,... 
RESISTANCE MECHANISM | SUPEROXIDE ANION | CHEMISTRY, MEDICINAL | ENZYME | INDOLEAMINE-2,3-DIOXYGENASE IDO | SUBSTRATE-INHIBITION | TRYPTOPHAN DEGRADATION | CYTOCHROME B | POTENT INHIBITORS | BINDING | RATIONAL DESIGN
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2014, Volume 84, pp. 284 - 301
Journal Article
Helvetica Chimica Acta, ISSN 0018-019X, 01/2012, Volume 95, Issue 1, pp. 34 - 42
FK866 (also named APO866 or WK175) is a potent NAMPT inhibitor being evaluated (Phase II) as a potential anticancer drug. The preparation of the... 
Ribofuranoside analogs, C‐imino | Inhibitors | Nicotinamide phosphoribosyltransferase | FK866 | Ribofuranoside analogs, C-imino | TARGET | CYANOGUANIDINE | ENZYMOLOGY | COMBINATION | CHEMISTRY, MULTIDISCIPLINARY | APO866 | POTENT ANTITUMOR-ACTIVITY | IN-VITRO | CHS 828 | Ribofuranoside analogs | VISFATIN | C-imino | NAD BIOSYNTHESIS INHIBITOR
Journal Article
by Bultet, Lisandra Aguilar and Aguilar-Rodríguez, José and Ahrens, Christian H and Ahrné, Erik Lennart and Ai, Ni and Aimo, Lucila and Akalin, Altuna and Aleksiev, Tyanko and Alocci, Davide and Altenhoff, Adrian and Alves, Isabel and Ambrosini, Giovanna and Pedone, Pascale Anderle and Angelino, Paolo and Anisimova, Maria and Appel, Ron and Argoud-Puy, Ghislaine and Arnold, Konstantin and Arpat, Bulak and Artimo, Panu and Ascencao, Kelly and Auchincloss, Andrea and Axelsen, Kristian and Gerritsen, Vivienne Baillie and Bairoch, Amos and Bansal, Parit and Baratin, Delphine and Barbato, Alessandro and Barbié, Valérie and Barras, David and Barreiro, Maria and Barret, Sophie and Bastian, Frederic and Neto, Teresamanuela Batista and Baudis, Michael and Beaudoing, Emmanuel and Beckmann, Jacques S and Bekkar, Amel Kawter and Ben Hamida Cammoun, Leila and Benmohammed, Sara and Bernard, Madeleine and Bertelli, Claire and Bertoni, Martino and Bienert, Stefan and Bignucolo, Olivier and Bilbao, Aivett and Bilican, Adem and Blank, Diana and Blatter, Marie-Claude and Blum, Lorenz and Bocquet, Jocelyne and Boeckmann, Brigitte and Bolleman, Jerven Tjalling and Bordoli, Lorenza and Bosshard, Lars and Bouchet, Gerard and Bougueleret, Lydie and Boutet, Emmanuel and Bovigny, Christophe and Bratulic, Sinisa and Breuza, Lionel and Bridge, Alan James and Britan, Aurore and Brito, Francisco and Frazão, Josias Brito and Bruggmann, Rémy and Bucher, Philipp and Burdet, Frédéric and Burger, Lukas and Cabello, Elena Maria and Gomez, Ruben Martin Cabezon and Calderon, Sandra and Cannarozzi, Gina and Carl, Sarah and Casas, Cristina Casals and Catherinet, Sebastien and Périer, Rouayda Cavin and Charpilloz, Christophe and Chaskar, Prasad Datatray and Chen, Weihua and Pepe, Anush Chiappino and Chopard, Bastien and Chu, Hoi Yee and Civic, Natacha and Claassen, Manfred and Clottu, Sylvie and Colombo, Martino and Cosandier, Isabelle and Coudert, Elisabeth and Crespo, Isaac and Creus, Marc and Cuche, Béatrice and Cuendet, Michel A and Cusin, Isabelle and Daga, Neha and Daina, Antoine and Dauvillier, Jér Ôme and David, Fabrice and Davydov, Iakov and De Sa Ricca Manadelo Ferreira, Mariana and ... and SIB Swiss Inst Bioinformatics
Nucleic Acids Research, ISSN 0305-1048, 2016, Volume 44, Issue 1, pp. D27 - D37
The SIB Swiss Institute of Bioinformatics (www.isb-sib.ch) provides world-class bioinformatics databases, software tools, services and training to the... 
PROTEIN MODELS | QUALITY | REGULATORY SITES | LANDSCAPE | KNOWLEDGEBASE | ARCHIVE | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPOSITORY | EXPRESSION DATA | TOOLS | PREDICTION | Database Issue
Journal Article
Synthesis, ISSN 0039-7881, 11/2007, Volume 2007, Issue 22, pp. 3469 - 3472
Abstract 2-Amino-4-alkyl- and 2-amino-4-arylthiazole-5-carboxylates and their selenazole analogues were synthesized by α-halogenation of β-keto esters with... 
paper | ACID | thiazoles | ANALOGS | CYCLODEXTRIN | CHEMISTRY, ORGANIC | beta-keto esters | NEUTRAL CONDITIONS | selenazoles | cyclodextrins | SELENIUM HETEROCYCLES | 2,4-DISUBSTITUTED THIAZOLES | N-bromosuccinimide | CLEAVABLE SURFACTANTS | 1,3-SELENAZINE DERIVATIVES | EFFICIENT | WATER
Journal Article
Helvetica Chimica Acta, ISSN 0018-019X, 02/2007, Volume 90, Issue 2, pp. 337 - 339
Thiolysis of thiiranes I with thiophenols II is performed efficiently in the presence of β‐cyclodextrin in water with high regioselectivity (Scheme, Table). 
Thiols, α‐(arylsulfanyl) | Thiophenols | β‐Cyclodextrin | Thiiranes | ASYMMETRIC-SYNTHESIS | AZIRIDINES | CHEMISTRY, MULTIDISCIPLINARY | COMPLEXES
Journal Article
Helvetica Chimica Acta, ISSN 0018-019X, 06/2007, Volume 90, Issue 6, pp. 1107 - 1111
A simple and mild procedure was developed for the first time for the C(3)‐selective ring opening of an aromatic 2,3‐epoxy alcohol, i.e., of... 
Alcohol, 2,3‐epoxy | Benzenethiolates | Phenoxide, sodium salt | Ring‐opening reaction | Cyclodextrins | Propane‐1,2‐diol | Thiophenoxide | HALIDES | ETHERS | EPOXY ALCOHOLS | COMPLEXES | NUCLEOPHILIC-SUBSTITUTION REACTIONS | ALPHA-AMINO-ACIDS | AZIDE | CHEMISTRY, MULTIDISCIPLINARY | ZEOLITE CAY
Journal Article
ChemInform, ISSN 0931-7597, 06/2007, Volume 38, Issue 25, pp. no - no
ChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform ,... 
mercaptans, thioethers (benzene compounds) | ring opening reactions
Journal Article
ChemInform, ISSN 0931-7597, 03/2008, Volume 39, Issue 13, pp. no - no
ChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform of an... 
thiazole derivatives | organo‐selenium compounds
Journal Article
ChemInform, ISSN 0931-7597, 10/2007, Volume 38, Issue 42, pp. no - no
ChemInform is a weekly ing Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform ,... 
phenol ethers | mercaptans, thioethers (benzene compounds) | ring opening reactions
Journal Article
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