X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (41) 41
humans (38) 38
male (23) 23
female (21) 21
article (19) 19
neurosciences (19) 19
middle aged (18) 18
adult (17) 17
clinical neurology (17) 17
genetic aspects (14) 14
aged (13) 13
genotype (13) 13
mutation (13) 13
research (13) 13
neurology (12) 12
amyotrophic lateral sclerosis (11) 11
genetics (10) 10
risk factors (10) 10
amyotrophic lateral sclerosis - genetics (9) 9
case-control studies (9) 9
parkinson's disease (9) 9
proteins - genetics (9) 9
abridged index medicus (8) 8
adolescent (8) 8
alzheimer's disease (8) 8
c9orf72 protein (8) 8
cohort studies (8) 8
dementia (8) 8
genetic predisposition to disease - genetics (8) 8
genetics & heredity (8) 8
parkinson disease - genetics (8) 8
phenotype (8) 8
aged, 80 and over (7) 7
amyotrophic-lateral-sclerosis (7) 7
animals (7) 7
child (7) 7
dna mutational analysis (7) 7
frontotemporal dementia (7) 7
frontotemporal dementia - genetics (7) 7
gene (7) 7
geriatrics & gerontology (7) 7
internal medicine (7) 7
mutation - genetics (7) 7
mutations (7) 7
pedigree (7) 7
young adult (7) 7
age of onset (6) 6
gene mutations (6) 6
genes (6) 6
genetic predisposition to disease (6) 6
genome-wide association (6) 6
nervous system diseases (6) 6
neurodegenerative diseases (6) 6
proteins (6) 6
age (5) 5
alleles (5) 5
alzheimer disease - genetics (5) 5
c9orf72 (5) 5
cancer (5) 5
deletions (5) 5
gene frequency (5) 5
genetic variation (5) 5
identification (5) 5
physiological aspects (5) 5
prevalence (5) 5
aging (4) 4
alzheimers-disease (4) 4
association (4) 4
common variants (4) 4
diagnosis (4) 4
dna repeat expansion (4) 4
dna repeat expansion - genetics (4) 4
dna-binding proteins - genetics (4) 4
exome (4) 4
gene expression (4) 4
genetic testing (4) 4
haplotypes (4) 4
health aspects (4) 4
identifies variants (4) 4
inflammation (4) 4
life sciences (4) 4
mental disorders (4) 4
molecular genetics (4) 4
neurodegeneration (4) 4
neurofibromatosis 1 - genetics (4) 4
neurons (4) 4
original (4) 4
parkinson’s disease (4) 4
population (4) 4
protein (4) 4
risk (4) 4
tdp-43 (4) 4
ubiquitin-protein ligases - genetics (4) 4
alpha-synuclein (3) 3
als (3) 3
alzheimers disease (3) 3
amyotrophic lateral sclerosis - epidemiology (3) 3
bioinformatics (3) 3
biological sciences (3) 3
cerebellum (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 7, pp. 2626 - 2631
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD.... 
Proteins | Neurites | Transfection | Neurons | Medical genetics | Parkinson disease | Disease risk | Genetic loci | Gene expression regulation | Genetic mutation | GAK | Trans-Golgi | BAG5 | Autophagy | RECRUITMENT | autophagy | PROTEIN | VARIANTS | LRRK2 | MULTIDISCIPLINARY SCIENCES | SEQUENCE | trans-Golgi | CLATHRIN | Cell Fractionation | Immunoprecipitation | Humans | Genetic Loci - genetics | Multiprotein Complexes - genetics | DNA Primers - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Brain - metabolism | Multiprotein Complexes - metabolism | Mass Spectrometry | HEK293 Cells | Plasmids - genetics | Golgi Apparatus - ultrastructure | Protein-Serine-Threonine Kinases - metabolism | rab GTP-Binding Proteins - metabolism | Genetic Predisposition to Disease - genetics | Protein-Serine-Threonine Kinases - genetics | Blotting, Western | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Microscopy, Confocal | Protein Interaction Mapping - methods | Analysis of Variance | Transport Vesicles - metabolism | Parkinson Disease - enzymology | Adaptor Proteins, Signal Transducing - metabolism | Genome-Wide Association Study - methods | Genetic aspects | Parkinson's disease | Leucine | Gene mutations | Health aspects | Phosphotransferases | Mutation | Kinases | Genes | Parkinsons disease | Index Medicus | Biological Sciences
Journal Article
by Majounie, Elisa, PhD and Renton, Alan E, PhD and Mok, Kin, MSc and Dopper, Elise GP and Waite, Adrian, PhD and Rollinson, Sara, PhD and Chiò, Adriano, MD and Restagno, Gabriella, MD and Nicolaou, Nayia, MSc and Simon-Sanchez, Javier, PhD and van Swieten, John C, Prof and Abramzon, Yevgeniya and Johnson, Janel O, PhD and Sendtner, Michael, Prof and Pamphlett, Roger, MD and Orrell, Richard W, MD and Mead, Simon, MD and Sidle, Katie C, MD and Houlden, Henry, Prof and Rohrer, Jonathan D, MD and Morrison, Karen E, Prof and Pall, Hardev, MD and Talbot, Kevin, Prof and Ansorge, Olaf, MD and Hernandez, Dena G, MSc and Arepalli, Sampath, MS and Sabatelli, Mario, MD and Mora, Gabriele, MD and Corbo, Massimo, MD and Giannini, Fabio, MD and Calvo, Andrea, MD and Englund, Elisabet, MD and Borghero, Giuseppe, MD and Floris, Gian Luca, MD and Remes, Anne M, Prof and Laaksovirta, Hannu, MD and McCluskey, Leo, MD and Trojanowski, John Q, Prof and Van Deerlin, Vivianna M, MD and Schellenberg, Gerard D, Prof and Nalls, Michael A, PhD and Drory, Vivian E, MD and Lu, Chin-Song, Prof and Yeh, Tu-Hsueh, MD and Ishiura, Hiroyuki, MD and Takahashi, Yuji, MD and Tsuji, Shoji, Prof and Le Ber, Isabelle, MD and Brice, Alexis, Prof and Drepper, Carsten, PhD and Williams, Nigel, PhD and Kirby, Janine, PhD and Shaw, Pamela, Prof and Hardy, John, Prof and Tienari, Pentti J, MD and Heutink, Peter, Prof and Morris, Huw R, MD and Pickering-Brown, Stuart, Prof and Traynor, Bryan J, Dr and Chromosome 9-ALS FTD Consortium and French Res Network FTLD FTLD ALS and ITALSGEN Consortium and French research network on FTLD/FTLD/ALS and Chromosome 9-ALS/FTD Consortium and Oncology and Pathology, Kamprad Lab and Lund University and Lunds universitet and Onkologi och Patologi, Kampradlab
Lancet Neurology, The, ISSN 1474-4422, 2012, Volume 11, Issue 4, pp. 323 - 330
Summary Background We aimed to accurately estimate the frequency of a hexanucleotide repeat expansion in C9orf72 that has been associated with a large... 
Neurology | PREVALENCE | MUTATIONS | LOBAR DEGENERATION | GENETICS | TDP-43 | CLINICAL NEUROLOGY | Frontotemporal Dementia - genetics | Cross-Sectional Studies | DNA Repeat Expansion - genetics | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Child, Preschool | Genotype | Male | Genetic Loci | Open Reading Frames - genetics | Young Adult | Chromosomes, Human, Pair 9 - genetics | Adolescent | Age of Onset | Aged, 80 and over | Adult | Female | Aged | Child | Cohort Studies | Medical research | Medical colleges | Care and treatment | Nervous system diseases | Neurosciences | Molecular genetics | Oncology, Experimental | Questions and answers | Amyotrophic lateral sclerosis | Research | Medicine, Experimental | Agriculture | Physicians (General practice) | Alzheimer's disease | Dementia | Cancer | Biomedical engineering | Index Medicus | Haplotypes | Polymerase chain reaction | Neurodegenerative diseases | Ethnic groups | Data processing | Mutation | Frontotemporal dementia | Genetic counselling | Islands | Age | Toll-Like Receptor 4 | Open Reading Frames | Adaptor Proteins, Vesicular Transport | Lipopolysaccharides | Life Sciences | DNA Repeat Expansion | Interferon Regulatory Factor-3 | Transfection | Amyotrophic Lateral Sclerosis | RNA Interference | HEK293 Cells | Membrane Glycoproteins | Vesicular Transport Proteins | Protein Structure, Tertiary | Cell Line | Chemokine CCL5 | Frontotemporal Dementia | Signal Transduction | Myeloid Differentiation Factor 88 | Chromosomes, Human, Pair 9 | Protein Transport | Adaptor Proteins, Signal Transducing | Santé publique et épidémiologie | RNA, Small Interfering | Endosomes | Neurologi | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 01/2013, Volume 368, Issue 2, pp. 117 - 127
Journal Article
by Sims, Rebecca and Van Der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and EADI and GERAD PERADES and ARUKConsortium and CHARGE and ADGC and GERAD/PERADES, CHARGE, ADGC, EADI and ARUK Consortium and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1373 - 1384
Journal Article
Journal of Neurology, ISSN 0340-5354, 4/2011, Volume 258, Issue 4, pp. 647 - 655
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 16890 - 12
Aging is a biologically universal event, and yet the key events that drive aging are still poorly understood. One approach to generate new hypotheses about... 
HIPPOCAMPUS | PATHWAYS | LONGEVITY | MULTIDISCIPLINARY SCIENCES | DISEASE | NEURONS | COEXPRESSION NETWORKS | PREFRONTAL CORTEX | CEREBRAL-CORTEX | AGE | Brain | Life span | Cortex (frontal) | Aging | Gene expression | Ribonucleic acid--RNA | Age | Index Medicus
Journal Article