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Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. SCI-9 - SCI-9
Abstract Over the past decade, the metabolic alterations that occur during tumorigenesis have been recognized as a key feature required for the transformation... 
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2018, Volume 28, Issue 6, pp. 811 - 813
Metabolic reprogramming is a hallmark of cancer cell metabolism. Recently, in , reported that leukemic cells have the capacity to modulate glucose metabolism... 
ENDOCRINOLOGY & METABOLISM | CELL BIOLOGY | Physiological aspects | Glucose metabolism | Leukemia
Journal Article
Immunity, ISSN 1074-7613, 07/2015, Volume 43, Issue 1, pp. 9 - 11
Passenger mutations specific to particular mouse strains can distort experimental outcomes. In this issue of , demonstrate that passenger mutations are... 
MICE | IMMUNOLOGY | Mice, Inbred C57BL - genetics | Genetic Variation - genetics | Animals | Genome - genetics | Genetic aspects | Genetically modified organisms | Proteins | Studies | Laboratories | Genes | Rodents | Stem cells | Genomes | Mutation | Research | Bioinformatics | Informatics | Deoxyribonucleic acid--DNA
Journal Article
Molecular Oncology, ISSN 1574-7891, 10/2019, Volume 13, Issue 10, pp. 2033 - 2048
Autophagy is a conserved self‐eating process that delivers cytoplasmic material to the lysosome to allow degradation of intracellular components, including... 
HECT E3 ubiquitin ligases | autophagy | proteasomal degradation | ubiquitylation | Biodegradation | Ubiquitin | Proteins | Enzymes | Neurodegeneration | Regulation | Kinases | Organelles | Autophagy | Neuromodulation | Phagocytosis | Cancer | Index Medicus | Review
Journal Article
Biographical Memoirs of Fellows of the Royal Society, ISSN 0080-4606, 04/2018, Volume 64, pp. 317 - 339
Journal Article
Molecular Immunology, ISSN 0161-5890, 11/2013, Volume 56, Issue 1-2, pp. 38 - 47
The continued global burden wrought by chronic infectious disease is unrelenting. Current therapies have curbed the severity of disease for patients, but Human... 
Journal Article
PLoS Pathogens, ISSN 1553-7366, 01/2014, Volume 10, Issue 1
  To be able to colonize its host, invading Salmonella enterica serovar Typhimurium must disrupt and severely affect host-microbiome homeostasis. Here we... 
Salmonella | Microbiological research | Physiological aspects | Homeostasis | Host-parasite relationships | Colitis | Research | Health aspects | Inflammatory bowel disease | Transcription factors | Rodents | Ligands | Infections
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 23, pp. 9572 - 9577
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 131, Issue 6, pp. 1027 - 1031
The 2007 Nobel Prize in Physiology or Medicine has been awarded to Mario Capecchi, Martin Evans, and Oliver Smithies for developing specific gene modification... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | PLURIPOTENTIAL CELLS | MOUSE EMBRYOS | LINE | CELL BIOLOGY | Gene Targeting | Nobel Prize | Sweden | Animals | Recombination, Genetic | Humans | Mice | Embryonic Stem Cells | Disease Models, Animal | Mice, Knockout | Embryonic stem cells | Analysis
Journal Article
Genes and Development, ISSN 0890-9369, 09/2012, Volume 26, Issue 18, pp. 2038 - 2049
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 4696 - 4696
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2010, Volume 120, Issue 11, pp. 4065 - 4076
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 11/2011, Volume 108, Issue 46, pp. 18766 - 18771
Mice deficient for interferon regulatory factor (Irf)2 (Irf2-/- mice) exhibit immunological abnormalities and cannot survive lymphocytic choriomeningitis virus... 
Acinar cells | Animal models | Transcription | Double-stranded RNA | Pancreatitis | Inflammation | Pattern recognition | TLR3 protein | Infection | Polymerase chain reaction | Trypsin | Cell death | Transcription activation | Toll-like receptors | alpha -Interferon | Interferon | Pancreas | Interferon regulatory factor
Journal Article
细胞研究:英文版, ISSN 1001-0602, 2012, Volume 22, Issue 3, pp. 447 - 449
Pyruvate kinase catalyzes the transfer of a high-energy phosphate group from phosphoenol pyruvate (PEP) to generate pyruvate and ATP, a reaction that is the... 
丙酮酸 | 磷酸盐 | 存活 | PEP | 酶催化 | ATP | 生长 | 细胞增殖 | CELLS | PYRUVATE-KINASE M2 | TARGETS | ISOFORM | TUMOR-GROWTH | CANCER | NUCLEAR TRANSLOCATION | CELL BIOLOGY | Neoplasms - metabolism | Carrier Proteins - metabolism | Cell Proliferation | Cell Survival | Thyroid Hormones - metabolism | Membrane Proteins - metabolism | Neoplasms - pathology | Research Highlight
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2004, Volume 113, Issue 12, pp. 1774 - 1783
Journal Article
Journal Article
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