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NATURE COMMUNICATIONS, ISSN 2041-1723, 08/2019, Volume 10, Issue 1, pp. 3799 - 15
Synthetic biology efforts for the production of valuable chemicals are frequently hindered by the structure and regulation of the native metabolic pathways of... 
SYNTHASE | PRECURSOR | DYNAMIC PATHWAY REGULATION | CDNA ISOLATION | ESSENTIAL OILS | FUNCTIONAL EXPRESSION | DIPHOSPHATE | MULTIDISCIPLINARY SCIENCES | MICROBIAL SYNTHESIS | SYNTHETIC BIOLOGY | GLANDULAR TRICHOMES | Chassis | Yeasts | Enzymes | Yeast | Biosynthesis | Selectivity | Metabolism | Substrates | Organic chemistry | Metabolic flux | Precursors | Metabolic pathways | Monoterpenes | Viability | Saccharomyces cerevisiae
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2016, Volume 113, Issue 13, p. 3681
  Synthetic biology approaches achieving the reconstruction of specific plant natural product biosynthetic pathways in dedicated microbial "chassis" have... 
Antioxidants | Enzymes | Yeast | Genomics | Biosynthesis | Oxidation
Journal Article
Nature chemical biology, ISSN 1552-4450, 12/2018, Volume 14, Issue 12, pp. 1090 - 1098
One application of synthetic biology is the redesign of existing biological systems to acquire new functions. In this context, expanding the chemical code... 
PELTATE GLANDS | CDNA ISOLATION | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | VOLATILES | STREPTOMYCES-COELICOLOR | DIPHOSPHATE SYNTHASE | FUNCTIONAL-ANALYSIS | DIVERSITY | IDENTIFICATION | 2-METHYLISOBORNEOL SYNTHASE | Proteins | Organic chemistry | Protein engineering | Yeast | Metabolites | Metabolic engineering | Terpenes | Chemical synthesis | Carbon | Redesign
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0124106
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 3110 - 3110
Abstract Recent evidence indicates that TAp63, the prevalent isoform of TP63 in Chronic Lymphocytic Leukemia (CLL), is implicated in disease pathogenesis. In... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1843 - 1843
Abstract We and others recently reported mutations within the RPS15 gene, encoding a component of the 40S ribosomal subunit, in clinically aggressive chronic... 
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, p. 8855
Plants synthesize numerous specialized metabolites (also termed natural products) to mediate dynamic interactions with their surroundings. The complexity of... 
PISIFERIC ACID | COMBINATORIAL BIOSYNTHESIS | CARNOSIC ACID | CHAMAECYPARIS-PISIFERA | CONIFER DEFENSE | PROMISCUITY | MULTIDISCIPLINARY SCIENCES | DIPHOSPHATE SYNTHASE | DIVERSITY | CYTOCHROME B | EXPRESSION | Acids | Metabolites | Natural products | Plasticity | Diterpenes | Metabolic engineering | Biosynthesis | Metabolism | Biological activity | Amino acid substitution
Journal Article
Computational and Structural Biotechnology Journal, ISSN 2001-0370, 10/2012, Volume 3, Issue 4
Technological developments over the past century have made microbes the work-horses of large scale industrial production processes. Current efforts focus on... 
Journal Article
Journal Article
Microbial Cell Factories, 01/2016, Volume 15
  Background Several plant diterpenes have important biological properties. Among them, forskolin is a complex labdane-type diterpene whose biological activity... 
Journal Article
Journal Article
Metabolic Engineering, ISSN 1096-7176, 01/2015, Volume 27, pp. 65 - 75
Terpenes have numerous applications, ranging from pharmaceuticals to fragrances and biofuels. With increasing interest in producing terpenes sustainably and... 
Protein engineering | Terpene synthase | Yeast |